奥仲 哲弥 おくなか てつや 先生

来歴等

略歴

1985年 東京医科大学卒業
1985年 東京医科大学第一外科入局　同生理学教室大学院入学
1988年 米国オハイオ州ケースウェスタンリザーブ大学に留学
1989年 京医科大学大学院修了 医学博士
1989年 ケースウェスタンリザーブ大学 講師
1997年 英国ロンドン大学医学部国立医用レーザー研究所 研究員
1999年 東京医科大学第一外科 講師
2003年 国際医療福祉大学臨床医学センター 教授
2003年 山王病院呼吸器 センター長
2005年 東京医科大学外科客員 教授
2006年 第16回 日本光線力学学会 会長
2007年 山王病院 副院長

論文

• Early detection of bronchial lesions using system of autofluorescence endoscopy(SAFE-1000)Diagnostic and Therapeutic Endoscopy 5: 85-90 1999

  M. Kakihana, K. Kyong IL, T. Okunaka

• A clinicopathological Study resected adenocarcinoma less than 2 cm in size Lung Cancer 41:50-54 2003

  Kato, H. Okunaka, T.

• Increased cytotoxix effects of photodynamic therapy in IL-6 gean treanfected cells via enhanced apoptosis Int J Cancer, 93:475-480 2001

  J. Usuda, T. Okunaka, K. Furukawa

• Localization of experimental submucosal esophageal tumor in rabbits bu using mono-Laspartyl chlorin e6 and long-wavelength photodynamic excitation Laser Surg Med 21: 83-89 2000

  Tetsuya Okunaka, Ilyar Sheyhedin, Harubumi Kato

• Fibrin plugging as a cause of microcirculatory occulusion during photodynamic therapyLaser Med Sci 14: 129-135 1999

  Yutaka Yamamoto, Hiroshi Shibuya, Tetsuya Okunaka

• Potential applications of photodyamic therapy Rev Contemp Pharmacother 10: 59-68 1999

  T. Okunaka and H. Kato

• Effectivences of photodynamic therapy and Nd-YAG laser treatment for obstructed tracheobronchial malignancies　Diagnostic and Therapeutic Endoscopy 5: 161-166 1999

  K. Furukawa, T. Okunaka, H. Yamamoto

• Lung cancers treated with photodynamic therapy and surgery Diagnostic and Therapeutic Endoscopy 5: 155-160 1999

  T. Okunaka, T. Hiyoshi, K. Furukawa

• Eeary detection of bronchial lesions using lung imaging fluorescence endoscope Diagnostic and Therapeutic Endoscopy 5: 99-104 1999

  N. Ikeda, H. Honda, T. Katsumi, T. Okunaka

• Histopathological evaluation of fluorescence bronchoscopy using resected lungs in cases of lung cancer Lung Cancer 41:303-309 2003

  Kato, H. Okunaka, T.

• vivo fluorescence kinetics of Mono-L-aspartyl chlorin e6 and fluorescence of angiogenesis in fibrosarcoma-bearing miceInt J Clin Oncol 3: 209-215　1998

  Masahiko Harada, K. Aizawa, T. OkunakaIn

• The effects of serum on cellular uptake and phototoxicity of mono-L-aspartyl chlorin e6 in vitroPhotochem and Photobiol 68: 110-114　1998

  Ilyar Sheyhedin, K. Aizawa, T. Okunaka

• Synchronous quadruple lung cancer treated curatively by photodynamic therapy　Diagnostic and Therapeutic Endoscopy 3: 115-119　1996

  M. Saito, H. Kato, T. Okunaka

• Photodynamic therapy for lung cancer with bronchial artery infusion of photofrinDiagnostic and Therapeutic Endoscopy 2: 203-206　1996

  T. Okunaka, H. Kato, C. Konaka

• Photodynamic therapy for early stage bronchogenic carcinoma　J. Clin Laser Medicine and Surgery 14: 235-238　1996

  H. Kato, T. Okunaka, H. Shimatani

• Combined use of photodynamic therapy and surgery　Ann Thorac and Cardiovasc Surg 1: 55-59　1995

  C. Konaka, T. Okunaka, H. Kato

• Photofrin photosensitization. Correlation of Photofrin: erythrocyte binding processes with photolysis　Int J Rad Biol 68: 37-46　1995

  K. Yamada, H. Yamamoto, T. Okunaka

• Photodynamic therapy for lung cancer J Thoracic Oncology 1:489-493 2006

  Usuda, J. Okunaka,T.

• New aspects of photodynamic therapy for central type early stage lung cancer　Lasers in Surgery and Medicine 43:749-754　2011

  Ikeda,N. Okuanaka,T.

• Breast cancer resistant protein (BCRP) is a molecular determinant of the out come of photodyanamic therapy for centrally located early lung cancer 　Lung cancer 67 :198-204 2010

  Usuda, L. Okunaka, T.

• High expression of GADD-45alpha and VEGF induced tumor recurrence via upregulation of IL-2 after photodynamic therapy using NPe6 Int J Oncol 32:397-403 2008

  Ohtani, K. Okunaka, T.

• Tailor-made approach to photodynamic therapy in the treatment of cancer based on Bcl-2 photodamage Int. Nal. J. Oncol. 33 689-696 2008

  Usuda,J. Okunaka, T.　

• Photodynamic therapy for lung cancers based on novel photodynamic diagnosisusing talaporfin sodium and autofluorescence bronchoscopy Lung Cancer 58:317-323 2007

  Usuda, J. Okunaka, T.

• A possible relationship between the anticancer potency of photodynamic therapy using the novel photosensitizer ATX-s10-Na and expression of the vascular endothelial growth factor in vivo Oncol Res 18:689-683 2007

  Usuda, J. Okuanka, T.

• Breast cancer resistant protein (BCRP) affected acquired resistance to gefitinib in a never-smoked female patient with advanced non-small cell lung cancer Lung Cancer 58: 296-299 2007

  Usuda, L. Okunaka, T.

• Basic clinical research on photodynamic therapy at Tokyo Medical University Hospital　Laser Surg Med　38：371-375　2006

  Kato, H, Okunaka,T.　

• Ten Year Disease-Free Survival of a Lung cancer Patient Treated Only by Photodynamic Therapy (PDT)　Laser in the Life Science 6: 9-14　1994

  H. Kato, C. Konaka, T. Okunaka

• Lysosomal cathepsin initiates apoptosisi, which is regulated by photodamage to Bcl-2 at mitochondoria in photodynamic therapy using a novel a novel photosensitizer, ATX-s10(Na) Int J Oncol 29:349-355

  Ichinose, S. Okuanka, T.

• Safety guidelines of PDT for early stage lung cancer Laser Therapy Vol.15 ,No3 101-104 2006

  Tetsuya Okunaka, Harubumi Kato

• Postoperative adjuvant therapy for completely resected early-stage non-small cell lung cancer Int J Clinical Oncology 10:157-164 2005

  Kato, H, Okunaka, T.

• Locally recurrent central-type early lung cancer＜1cm in diameter after complete remission by photodynamic therapy Chest 128:3269-3275 2005

  Furukawa, K. Okuanka, T.

• Photodynamic therapy for peripheral lung cancer, Lung Cancer 43, 77-82, 2004

  Okunaka, T, Kato, H, Furukawa, K, et. Al

• Histopathplogical evaluation of fluorescence bronchology using resected lungd in cases of lung cancer Lung Cancer 41:303-309 2003

  Ikeda, N.,Okunaka, T.

• Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early stage superficial squamous cell carcinoma of the lung Lung Cancer 42:103-111 2003

  Kato, H., Furukawa, K., Okunaka.T

• Hematoporphyrin derivative uptake by atheroma in atherosclerotic rabbits: The fluorescence from HpD demonstrated by an excimer dye laser Photochemistry and Photobiology 46: 769-775　1987

  T. Okunaka, H. Kato, K. Aizawa

• Photodynamic therapy of esophageal　 Endoscopy 4: 150-153 1990

  T. Okunaka, H. Kato, C. Konaka

• Photodynamic therapy for multiple primary bronchogenic carcinoma　Cancer 68: 253-258　1991

  T. Okunaka, H. Kato, C. Konaka

• Detection of experimental atheroma in atherosclerotic rabbits; the fluorescence spectrum of HpD obtained in situ by angioscopic fluorescence spectrophotometryLasers in Medical Science 6: 7-13　1991

  T. Okunaka, K. Aizawa, H. Kato

• Correlation between photodynamic efficacy of differing porphyrins and membrane partitioning behavior　Lasers Surg and Med, 12: 98-103　1992

  T. Okunaka, M. L. Eckhauser, H. Kato

• A Comparison between argon-dye amd excimer dye laser for photodynamic effect in transplanted mouse tumorJpn J cancer Res 83: 226-231　1992

  T. Okunaka, H. Kato, C. Konaka

• Detection of experimental atheroma in vivo with a new excimer laser fluorescence angioscope　Jpn J Thorscic Surg 12: 507-511　1992

  T. Okunaka, H. Kato, C. Konaka

• Primary lung cancer producing alpha-fetoprotein　Ann Thorac Surg. 53: 151-152　1992

  T. Okunaka, H. Kato, C. Konaka

• A prospective phase Ⅱ study on photodynamic therapy with photofrin Ⅱ for centrally located early-stage lung cancer　J. Clin Oncol 11: 1852-1857　1993

  K. Furuse*, M. Fukuoka*, H. Kato, T,Okunaka

• Photodynamic therapy in early stage lung cancerLung Cancer 9: 287-294　1993

  Y. Hayata, H. Kato, T. Okunaka

著書

• 「Thorax Surgery」Photodynamic therapy for central type lung cancer

• 「インフォームドコンセントのための図説シリーズ」　

• 「肺癌診療ニ頁の秘訣」

• 「外科病棟・手術室のリスクマネージメント」

• 「Applied Laser Medicine」

• 「ポストゲノム時代の内視鏡学」

• 「PDTハンドブック」

• 「肺癌、診断・治療の要点」　気管支鏡検査-組織診、細胞診、細径気管支ファイバースコープ

• 「肺癌治療ハンドブック」　レーザー治療

• 「呼吸器系マニュアル」蛍光気管支鏡（肺癌に早期発見）

• 「医師国家試験問題解説書」

• 「禁煙バトルロワイヤル」

• 「がん治療を受ける前に知っておきたい55のこと」

• 「たばこを吸っている人、吸っていた人が健康のためにできること」

• 「図解　がん治療を受ける前に知っておきたい55のこと」

• 「最高のがん治療を受ける方法―病院選びから、三大治療、治療費まで」

• 「長生きしたけりゃ『肺活』しなさい」

• 「『余命3ヶ月』と伝えるときの医者のホンネ」

• がんの早期発見と治療の手引き

• 「肺癌・MDアンダーソン癌センターに学ぶ癌診療」　早期(I期、II期）非小細胞肺癌の治療　

• 「呼吸器専門医テキスト」　気管支内視鏡治療（レーザー等）　奥仲哲弥　（共著）南江堂　2007患者さんの疑問に答える｢胃がん｣｢肺がん｣｢乳がん｣「大腸がん」肺がん

• 「次世代光医療－レーザー技術の臨床への橋渡し-」　光線力学的治療の適応拡大と将来　

• 「肺癌診療Q&A」　禁煙対策　レーザー治療