市川 肇 先生のプロフィール

市川 肇 先生

いちかわ はじめ

市川 肇 先生

国立研究開発法人 国立循環器病研究センター 小児心臓外科

専門分野

先天性心疾患全般

紹介

小児心臓外科手術、小児補助循環の専門家。先天性心疾患を専門とする。国内外の心臓病の子供たちを救うプロジェクトの中心となり治療を行うなど、海外への医療支援にも携わっている。心疾患に苦しむ子どもたちの命を救うべく、日々患者とともに疾患と闘っている。日本小児循環器学会理事。日本成人先天性心疾患学会会長。

略歴

1984年 大阪大学医学部附属病院医員(研修医)
1987年 国立循環器病センター心臓血管外科 レジデント
1990年 英国セントトーマス病院レイン研究所研究員
1993年 大阪警察病院副医長
1994年 大阪大学医学部第一外科
1996年 米国ミシガン大学小児病院招聘講師
1998年 大阪大学医学部助手
(2000年~2001年)米国ミシガン大学附属病院心臓肺移植フェロー)
2006年 大阪大学外科学講座人工心臓外科 特任教授 
2009年 国立循環器病研究センター心臓血管外科医長
2010 年 国立循環器病研究センター小児心臓外科部長(~現在)

所属学会・資格・役職など

日本成人先天性心疾患学会 理事
第18回日本成人先天性心疾患学会総会・学術集会 会長
日本小児循環器学会 理事
日本胸部外科学会 評議員・認定医
日本外科学会 専門医
日本心臓血管外科学会 評議員
心臓血管外科専門医・修練指導者
日本人工臓器学会、関西胸部外科学会 評議員
日本移植学会
日本心臓移植研究会
日本心臓病学会
日本循環器学会
ASCVTS
AATS

受賞・著書・論文など

【主要論文】
1. Hoashi T, Ichikawa H, Fukushima N, Ueno T, Kogaki S, Sawa Y: Long-term clinical outcome of atrial isomerism after univentricular repair. J Card Surg, 24: 19-23, 2009.
2. Hoashi T, Ichikawa H, Ueno T, Kogaki S, Sawa Y: Steroid pulse therapy for protein-losing enteropathy after the Fontan operation. Congenit Heart Dis, 4: 284-287, 2009.
3. Hoashi T, Matsumiya G, Miyagawa S, Ichikawa H, Ueno T, Ono M, Saito A, Shimizu T, Okano T, Kawaguchi N, Matsuura N, Sawa Y: Skeletal myoblast sheet transplantation improves the diastolic function of a pressure-overloaded right heart. J Thorac Card

【主要論文】
1. Hoashi T, Ichikawa H, Fukushima N, Ueno T, Kogaki S, Sawa Y: Long-term clinical outcome of atrial isomerism after univentricular repair. J Card Surg, 24: 19-23, 2009.
2. Hoashi T, Ichikawa H, Ueno T, Kogaki S, Sawa Y: Steroid pulse therapy for protein-losing enteropathy after the Fontan operation. Congenit Heart Dis, 4: 284-287, 2009.
3. Hoashi T, Matsumiya G, Miyagawa S, Ichikawa H, Ueno T, Ono M, Saito A, Shimizu T, Okano T, Kawaguchi N, Matsuura N, Sawa Y: Skeletal myoblast sheet transplantation improves the diastolic function of a pressure-overloaded right heart. J Thorac Cardiovasc Surg, 138: 460-467, 2009.
4. Nishi H, Takahashi T, Ichikawa H, Matsumiya G, Matsuda H, Sawa Y: Prediction of postoperative hepatic dysfunction after cardiac surgery in patients with chronic congestive heart failure. Gen Thorac Cardiovasc Surg, 57: 357-362, 2009.
5. Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y: Long-term medical control of inflow cuff infection in a patient with a left ventricular assist system. J Artif Organs, 12: 58-60, 2009.
6. Saito S, Matsumiya G, Sakaguchi T, Fujita T, Kuratani T, Ichikawa H, Sawa Y: Fifteen-year experience with Toyobo paracorporeal left ventricular assist system. J Artif Organs, 12: 27-34, 2009.
7. Yamamoto H, Yamamoto F, Ichikawa H: Enhanced coronary vascular turgor effect on post-ischemic diastolic function in hypertrophied hearts. Interact Cardiovasc Thorac Surg, 9: 605-608, 2009.
8. Kitamura S, Yagihara T, Kobayashi J, Nakajima H, Toda K, Fujita T, Ichikawa H, Ogino H, Nakatani and Taniguchi S.: Mid-to long-term outcomes of cardiovascular tissue replacements utilizing homografts harvested and stored at Japanese Institutional tissue banks. Surg Today 41: 500-509, 2011.
9. Ohuchi H, Kagisaki K, Miyazaki A, Kitano M, Yazaki S, Sakaguchi H, Ichikawa H, Yamada O, Yagihara T; Impact of the evolution of the Fontan operation on early and late mortality: a single-center experience of 405 patients over 3 decades. Ann Thorac Surg, 92(4):1457-66, 2011.
10. Hoashi T, Kagisaki K, Sakaguchi H, Ichikawa H; Normalization of pulmonary vascular resistance long after successful primary sutureless repair for congenital pulmonary vein stenosis. Pediatr Cardiol, 32(8): 1209-11, 2011.
11. Adachi I, Ueno T, Ichikawa H, Kagisaki K, Ide H, Hoashi T, Kogaki S, Ohuchi H, Yagihara T, Sawa Y; Effect of ventricular volume before unloading in a systemic ventricle supporting the Fontan circulation. Am J Cardiol, 107(3): 459-65, 2011.
12. Hoashi T, Kagisaki K, Oda T, Ichikawa H; Staged biventricular repair for persistent truncus arteriosus with aortic arch obstruction following bilateral pulmonary artery banding. Interact Cardiovasc Thorac Surg, 12(2): 281-3, 2011.
13. Hoashi T, Kagisaki K, Kitano M, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Late clinical features of patients with pulmonary atresia or critical pulmonary stenosis with intact ventricular septum after biventricular repair. Annals of Thoracic Surgery, 94: 833-841; discussion 841, 2012
14. Murashita T, Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Long-term results of mitral valve repair for severe mitral regurgitation in infants: fate of artificial chordae. Ann Thorac Surg, 94: 581-586, 2012.
15. Oda T, Hoashi T, Kagisaki K, Shiraishi I, Yagihara T, Ichikawa H: Alternative to pulmonary allograft for reconstruction of right ventricular outflow tract in small patients undergoing the Ross procedure. Eur J Cardiothorac Surg, 42: 226-232, 2012.
16. Shimada M, Hoashi T, Kagisaki K, Oda T, Shiraishi I, Kurosaki K, Kitano M, Ichikawa H: One-stage repair with separated cardiopulmonary bypass for coarctation of the aorta with left aortic arch and right thoracic descending aorta. Gen Thorac Cardiovasc Surg, 60: 575-577, 2012.
17. Shimada M, Hoashi T, Kagisaki K, Shiraishi I, Yagihara T, Ichikawa H: Clinical outcomes of prophylactic Damus-Kaye-Stansel anastomosis concomitant with bidirectional Glenn procedure. J Thorac Cardiovasc Surg, 143: 137-143, 2012.
18. Shiraishi I, Kurosaki K, Kanzaki S, Takeda M, Ichikawa H: A new method of manufacturing flexible heart replicas of congenital heart disease for simulation surgery in combination of stereolithography and vacuum casting method. European Heart Journal, 33: 408-408, 2012.
19. Torigoe T, Sakaguchi H, Kitano M, Kurosaki K, Shiraishi I, Kagizaki K, Ichikawa H, Yagihara T: Clinical characteristics of acute mitral regurgitation due to ruptured chordae tendineae in infancy-experience at a single institution. Eur J Pediatr, 171: 259-265, 2012.
20. Ueno T, Fukushima N, Sakaguchi T, Ide H, Ozawa H, Saito S, Ichikawa H, Sawa Y: First pediatric heart transplantation from a pediatric donor heart in Japan. Circulation Journal, 76: 752-754, 2012
21. Fujiyoshi T, Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Ichikawa H: The application of all-autologous three-sinus repair for supravalvular pulmonary stenosis. Pediatr Cardiol, 34: 1711-1715, 2013.
22. Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Late left ventricular function after successful Ross-Konno operation. Ann Thorac Surg, 96: 196-201, 2013.
23. Hoashi T, Kagisaki K, Miyazaki A, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Anatomic repair for corrected transposition with left ventricular outflow tract obstruction. Ann Thorac Surg, 96: 611-620, 2013.
24. Hoashi T, Kagisaki K, Oda T, Kitano M, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Long-term results of treatments for functional single ventricle associated with extracardiac type total anomalous pulmonary venous connection. Eur J Cardiothorac Surg, 43: 965-970, 2013.
25. Hoashi T, Kagisaki K, Okuda N, Shiraishi I, Yagihara T, Ichikawa H: Indication of Takeuchi technique for patients with anomalous origin of the left coronary artery from the pulmonary artery. Circ J, 77: 1202-1207, 2013.
26. Hoashi T, Kagisaki K, Yamashita K, Tatsumi E, Nishigaki T, Yoshida K, Hayashi T, Ichikawa H: Early clinical outcomes of new pediatric extracorporeal life support system (Endumo (2000) in neonates and infants. J Artif Organs, 16: 267-272, 2013.
27. Hoashi T, Kagisaki K, Meng Y, Sakaguchi H, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Long-term outcomes after definitive repair for tetralogy of Fallot with preservation of the pulmonary valve annulus. J Thorac Cardiovasc Surg, 148: 802-808; discussion 808-809, 2014.
28. Hoashi T, Kagisaki K, Nishigaki T, Yoshida K, Hayashi T, Ichikawa H: Efficacy of new pediatric extra-corporeal life support system (Endumo 2000) for postoperative management after Norwood operation. J Artif Organs, 17: 315-320, 2014.
29. Misumi Y, Hoashi T, Kagisaki K, Kitano M, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Long-term outcomes of common atrioventricular valve plasty in patients with functional single ventricle. Interact Cardiovasc Thorac Surg, 18: 259-265, 2014.
30. Morimoto K, Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Ichikawa H: Post-operative left atrioventricular valve function after the staged repair of complete atrioventricular septal defect with tetralogy of Fallot. Gen Thorac Cardiovasc Surg, 62: 602-607, 2014.
31. Shiraishi I, Nishimura K, Sakaguchi H, Abe T, Kitano M, Kurosaki K, Kato H, Nakanishi T, Yamagishi H, Sagawa K, Ikeda Y, Morisaki T, Hoashi T, Kagisaki K, Ichikawa H: Acute rupture of chordae tendineae of the mitral valve in infants: a nationwide survey in Japan exploring a new syndrome. Circulation, 130: 1053-1061, 2014.
32. Yamashita K, Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Yagihara T, Ichikawa H: Midterm outcomes of sutureless technique for postoperative pulmonary venous stenosis. Gen Thorac Cardiovasc Surg, 62: 48-52, 2014.
33. Hoashi T, Kagisaki K, Kurosaki K, Kitano M, Shiraishi I, Ichikawa H: Intrinsic Obstruction in Pulmonary Venous Drainage Pathway is Associated with Poor Surgical Outcomes in Patients with Total Anomalous Pulmonary Venous Connection. Pediatr Cardiol, 36(2): 432-437, 2015.
34. Hoashi T, Yazaki S, Kagisaki K, Kitano M, Kubota SM, Shiraishi I, Ichikawa H: Management of ostium secundum atrial septal defect in the era of percutaneous trans-catheter device closure: 7-Year experience at a single institution. J Cardiol, 65(5): 418-422, 2015.
35. Misumi Y, Hoashi T, Kagisaki K, Yazaki S, Kitano M, Kurosaki K, Shiraishi I, Ichikawa H: The Importance of Hybrid Stage I Palliation for Neonates with Critical Aortic Stenosis and Reduced Left Ventricular Function. Pediatr Cardiol, 36(4): 726-731, 2015.
36. Sakaguchi H, Miyazaki A, Yamada O, Kagisaki K, Hoashi T, Ichikawa H, Ohuchi H: Cardiac resynchronization therapy for various systemic ventricular morphologies in patients with congenital heart disease. Circ J, 79: 649-655, 2015.
37. Morimoto K, Hoashi T, Kagisaki K, Yoshimatsu J, Shiraishi I, Ichikawa H, Kobayashi J, Nakatani T, Yagihara T, Kitamura S, Fujita T: Impact of Ross Operation on Outcome in Young Female Adult Patients Wanting to Have Children. Circ J, 79: 1976-1983, 2015.
38. Moon J, Hoashi T, Kagisaki K, Kurosaki K, Shiraishi I, Ichikawa H: Clinical outcomes of mitral valve replacement with the 16-mm ATS advanced performance valve in neonates and infants. Ann Thorac Surg, 99: 653-659, 2015.
39. Kusajima K, Hoashi T, Kagisaki K, Ohuchi H, Shiraishi I, Ichikawa H: Reoperative double ventricular outflow tract reconstruction in grown-up congenital heart disease patients with conotruncal anomalies. Gen Thorac Cardiovasc Surg, 2015.
40. Ichikawa H, Bang JH, Alsoufi B, Yun TJ, Cameroon D: Anatomic variability of the thoracic duct in pediatric patients with complex congenital heart disease Discussion. Journal of Thoracic and Cardiovascular Surgery, 150: 495-496, 2015.
41. Hoashi T, Miyata H, Murakami A, Hirata Y, Hirose K, Matsumura G, Ichikawa H, Sawa Y, Takamoto S: The current trends of mortality following congenital heart surgery: the Japan Congenital Cardiovascular Surgery Database. Interact Cardiovasc Thorac Surg, 21: 151-156, 2015.
42. Hoashi T, Kagisaki K, Moon J, Takahashi Y, Hayashi T, Ichikawa H: Suspected cold agglutination during mild hypothermic pediatric open heart surgery: a report of two cases. J Artif Organs, 2015.
43. Hoashi T, Shiraishi I, Ichikawa H: Surgical experience for prolapse of both atrioventricular valves in a patient with filamin A mutation. Cardiol Young, 25(2): 365-367, 2015.

【総説】
44. Ichikawa H: Controlled reperfusion. Gen Thorac Cardiovasc Surg, 60: 65-67, 2012.
45. Shiraishi I, Ichikawa H: Human heterotaxy syndrome - from molecular genetics to clinical features, management, and prognosis. Circulation Journal, 76: 2066-2075, 2012.

【Case Report】
46. Kondoh H, Ichikawa H, Shintani H: Reduction of atrioventricular valve regurgitation by atrioventricular sequential pacing for an adult with corrected transposition of the great arteries. Pediatr Cardiol, 30: 52-54, 2009.
47. Saito S, Matsumiya G, Ueno T, Sakaguchi T, Kuratani T, Ichikawa H, Sawa Y: Bench replacement of donor aortic valve before orthotopic heart transplantation. J Heart Lung Transplant, 28: 981-983, 2009.
48. Adachi I, Ichikawa H, Ueno T, Hori Y, Kuratani T, Matsumiya G, Sawa Y: Histologic findings in a dilated atrium serving as a Fontan pathway for 23 years. Ann Thorac Surg, 89: 2022-2024, 2010.
49. Inoue M, Minami M, Fukushima N, Ichikawa H, Sawa Y, Okumura M, Date H: Bilateral lung transplantation with closure of ventricular septal defect in a patient with Eisenmenger syndrome. Gen Thorac Cardiovasc Surg, 58: 25-28; discussion 29, 2010.
50. Kondoh H, Ichikawa H, Shintani H: Herniated aortic valve contributes to obstruction in double-chambered right ventricle. Tex Heart Inst J, 37: 608-609, 2010.
51. Matsumoto Y, Hoashi T, Kagisaki K, Ichikawa H: Successful surgical treatment of a gigantic congenital coronary artery fistula immediately after birth. Interact Cardiovasc Thorac Surg, 15: 520-522, 2012
52. Misumi Y, Hoashi T, Kagisaki K, Ichikawa H: Advancing cor triatriatum in Fontan circulation: case report. Ann Thorac Surg, 95(4): 1450-1452, 2013.
53. Sawa Y, Matsumiya G, Shigemura S, Nishi H, Ichikawa H, Minami M, Fukushima N, Inoue M, Ueno T, Sawabatav A, Sakaguchi T, Saito S, Okumura M: The first successful heart-lung transplantation in Japan: report of a case. Surg Today, 43: 1461-1466, 2013.
54. Kusajima K, Hoashi T, Kagisaki K, Yoshida K, Nishigaki T, Hayashi T, Ichikawa H: Clinical experience of more than 2 months usage of extracorporeal membrane oxygenation (Endumo®4000) without circuit exchange. J Artif Organs, 17(1): 99-102, 2014.
55. Matsuda H, Fukushima N, Ichikawa H, Sawa Y: Orthotropic heart transplantation for adult congenital heart disease: a case with heterotaxy and dextrocardia. Gen Thorac Cardiovasc Surg, 2015.
56. Kawamoto N, Hoashi T, Kagisaki K, Watanabe K, Ichikawa H: Myers' 3-sinus reconstruction for supravalvular aortic stenosis involving left coronary ostium: report of a case. Surg Today, 45(8): 1064-1066, 2015.

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