岩田 猛 いわた たける 先生

来歴等

略歴

1980年 愛媛大学医学部卒業
1985年 愛媛大学医学部大学院卒業　医学博士取得
1985年 貞本病院循環器科部長
1986年 町立吉田総合病院内科医長
1987年 愛媛大学医学部助手
1987年 米国留学(ルイジアナ州アルトン・オクスナー 研究所)
1990年 愛媛大学医学部学部講師
1992年 市立八幡浜総合病院内科医長
2002年 市立八幡浜総合病院副院長
2008年 独立行政法人国立病院機構愛媛病院副院長
2011年 独立行政法人国立病院機構愛媛病院院長
2013年 独立行政法人国立病院機構愛媛医療センター院長（名称変更）

論文

1. T.Kokubu, K.Hiwada, Y.Sato, T.Iwata, Y.Imamura, R.Matsuda, H.Kogan, M.Yamazaki, Y.Iijima, Y.Baba.　Highly potent and specific inhibitors of human renin. Biochemical and Biophysical Research Communication 1984; 118(3): 929-933
2. Takeru Iwata, Haruhisa Hashimoto, Kunio Hiwada, Tatsuo Kokubu. Changes of plasma renin activity by intraventricular administration of biological active peptides in conscious rats. Clinical and Experimental Hypertension 1984; A6(5):1055-1066.
3. T.Iwata, K.Hiwada, E.Murakami, T.Kokubu. Effects of intracerebroventricular administration of biological active peptides on plasma renin activity in conscious rats. Clinical and Experimental Hypertension 1984; A6(10&11): 1787-1790.
4. Takeru Iwata, Kunio Hiwada, Tatsuo Kokubu. Changes of plasma renin activity following intracerebroventricular administration of biologically active peptides in two-kidney one clip hypertensive rats. Japanese Heart Journal 1984; 26(4): 567-575.
5. Takeru Iwata, Kunio Hiwada, Tatsuo Kokubu. Effects of renal denervation on renin release induced by intracerebroventricular administration of biological active peptides in conscious rats. Neuropeptides 1985; 6: 437-443.
6. Takeru Iwata, Kunio Hiwada, Eiki Murakami, Tatsuo Kokubu. Effects of intracerebroventricular administration of biologically active peptides on renin release in normal, renovascular hypertensive and renal denervated rats. Elsevier Science Publishers B. V. Brain & blood pressure control. K.Nakamura ed. 1986; pp281-285.
7. Kazutaka Nishimura, Takeru Iwata, Tatsuo Kokubu. Plasma half-life and organ uptake ratio of radiolabeled glandular kallikrein in control and nephrectomized rats. Plenum Publishing Corp. Kinin IV, Part A, 1987; pp309-313.
8. Eiki Murakami, Takeru Iwata, Kunio Hiwada, Tatsuo Kokubu. Brain glutathione and blood pressure control. Journal of Cardiovascular Pharmacology 1987; 10(Suppl 12): S112-S115.
9. Takeru Iwata, Eric Hardee, Edward D.Frohlich, Francis E.Cole. Amiloride enhances atrial natriuretic factor stimulation of cGMP accumulation in rat glomeruli. Peptides 1989; 10(3): 575-579.
10. Francis E.Cole, Ugo Rovigatti, Takeru Iwata, Jean Vaughn, Edward D.Frohlich. Atrial natriuretic factor effects on cyclic nucleotides in a human renal cell line. Hypertension 1989; 13(6): 799-803.
11. Francis E.Cole, Issac Rondon, Takeru Iwata, Eric Hardee. Effect of ATP and amiloride on ANF binding and stimulation of cyclic GMP accumulation in rat glomerular membranes. Life Science 1989; 45(6): 477-484.
12. Takeru Iwata, Jean Vaughn, Edward D.Frohlich, Francis E.Cole. Phorbol and calcium decreased atriopeptin response in human renal cell line. Peptides; 12(2): 301-307.
13. Yutaka Kitami, Kunio Hiwada, Eiki Murakami,Takeru Iwata, Shinjiro Muneta, Tatsuo Kokubu. Kidney renin gene expression after renin inhibition in the marmoset. Clinical Science 1991; 81(3): 387-392.
14. Takafumi Okura, Yutaka Kitami, Takeru Iwata, Kunio Hiwada. Quantitative measurement of extra-renal renin mRNA by polymerase chain reaction. Biochemical and Biophysical Research Communication 1991; 179(1): 25-31.
15. Takeru Iwata, Shinjiro Muneta, Yutaka Kitami, Takafumi Okura, Yasuko Ii,
Eiki Murakami, Kunio Hiwada.Effect of renal denervation on the development of hypertension in Dahl-Iwai salt-sensitive rats. Japanese Journal of Nephrology 1991; 33(9): 867-871.
16. Shinjiro Muneta, Eiki Murakami, Takumi Sumimoto, Takeru Iwata, Kunio Hiwada, Yuzuru Sato, Yoichi Imamura. Blood pressure and heart rate variability in elderly patients with isolated systolic hypertension. Journal of Human Hypertension 1991; 5: 393-398.
17. Takeru Iwata, Yasunobu Dazai, Yutaka Kitami, Shinjiro Muneta, Yoichi Imamura, Eiki Murakami, Kunio Hiwada. Response of plasma renin-angiotensin system to a single captopril administration in patients receiving long-term treatment with captopril. Clinical and Experimental Pharmacology and Physiology 1992; 19: 705-709.
18. Takafumi Okura, Yutaka Kitami, Rumi Wakamiya, Takeru Iwata, Kunio Hiwada.
Renin gene restriction fragment length polymorphisms in a Japanese family with a high incidence of essential hypertension. Clinical and Experimental Pharmacology and Physiology 1992; 19(Suppl 20): 17-19.
19. Takafumi Okura, Yutaka Kitami, Rumi Wakamiya, Kazumasa Marumoto, Takeru Iwata, Kunio Hiwada. Renal and extra-renal renin gene expression in spontaneously hypertensive rats. Blood Pressure 1992; 1(Suppl 3): 6-11.
20. Yutaka Kitami, Takafumi Okura, Rumi Wakamiya, Kazumasa Marumoto, Takeru Iwata, Kunio Hiwada. Regulation of the gene expression of type-1 angiotensin II receptor in spontaneously hypertensive rats. Blood Pressure 1992; 1(Suppl 3): 12-16.
21. Shinjiro Muneta, Yasunobu Dazai, Takeru Iwata, Kunio Hiwada, Katsuyuki Hamada, Shunpei Matsuura, Eiki Murakami, Yuzuru Sato, Yoichi Imamura. Baroreceptor reflex impairment in climacteric and ovariectomized hypertensive women. Hypertension Research 1992; 15: 27-32.
22. Takumi Sumimoto, Eiki Murakami, Takeru Iwata, Yasumobu Dazai, Kunio Hiwada.
Left ventricular cardiac structure and diastolic function in isolated systolic hypertension in the elderly. Journal of Human Hypertension 1993; 7: 3-6.
23. Yasunobu Dazai, Takeru Iwata, Kunio Hiwada. Augmentation of the renal tubular dopaminergic activity by oral calcium supplmentation in patients with essential hypertension. American Journal of Hypertension 1993; 6: 933-937.
24. Yasunobu Dazai, Takeru Iwata, Kunio Hiwada. Augmentation of baroreceptor reflex function by oral calcium supplementation in essential hypertension. Clinical and Experimental Pharmacology and Physiology 1994; 21: 173-178.
25. Akihiro Nagae, Katsuhiko Kohara, Takeru Iwata, Seiji Matsuda, Masahiro Sakanaka, Kunio Hiwada.Effect of dietary NaCl on tyrosine hydroxylase in the superior cervical ganglia of Dahl rats. Neuroscience Letters 1995; 190: 13-16.
26. Yasunobu Dazai, Katsuhiko Kohara, Takeru Iwata, Takumi Sumimoto, Kunio Hiwada.
Cardiovascular effct of oral calcium supplementation: Echocardiographic study in patients with essential hypertension. Angiology 1996; 47: 273-280.
27. K. Kohara, N. Hara-Nakamura, Y. Takada, T. Iwata, T. Ochi, H. Kukita, S. Muneta and K. Hiwada. Effect of alacepril on 24-hour blood pressure in elderly hypertensive patients. International Journal of Clinical Pharmacology and Therapeutics 1996; 34: 380-383.
28. Koji Kodama, Mareomi Hamada, Taishi Kuwahara, Michitsugu Nakamura, Yuji Shigematsu, Kunio Hiwada, Takeru Iwata, Yoshinobu Hoshii. Rest-redistribution thallium-201 myocardial scintigraphic study in cardiac amyloidosis. International Journal of Cardiac Imaging 1999; 15: 371-378.
29. Makoto Suzuki, Kozo Yamamoto, Seiitirou Watanabe, Takeru Iwata, Mareomi Hamada, Kunio Hiwada. Association between elevated brain natriuretic peptide levels and the development of left ventricular hypertrophy in patients with hypertension. American Journal of Medicine 2000; 108: 627-633.
30. Koji Kodama-Takahashi, Kiyotaka Ohshima, Kozo Yamamoto, Takeru Iwata, Mareomi Hamada, Eiki Murakami. Occurrence of Transient U-Wave Inversion During Vasospastic Anginal Attack is Not Related to the Direction of Concurrent ST-Segment Shift. Chest 2002; 122: 535-541.
31. Koji Kodama-Takahasshi, Akira Kurata, Kiyotaka Ohshima, Kozo Yamamoto, Shigeki Uemura, Seiichiro Watanabe, Takeru Iwata. Effect of Cilostazol on the ventricular escape rate and neurohumoral factors in patients with third-degree atrioventricular block. Chest 2003; 123: 1161-1169.
32. N Morioka, J Funada, Y Takata, H Hashida, T Iwata, J Higaki, H Okayama. Influence of meal intake on pulse wave indices in type 2 diabetes. Hypertens Res 2010; 33: 743-747.

著書

【総説】
１．共著：カプトプリルの主な薬理作用と臨床応用、薬局と調剤、1983
２．共著：昇圧・降圧に関与する物質の意義、総合臨床、1984
３．共著：ＡＣＥ阻害薬−高血圧と心臓、Therapeutic Research、1989
４．共著：Clinical and physiologic significance of local tissure renin-angiotensin system.　 American Journal of Medicine、1989
５．共著：過労と高血圧、臨床成人病、1990
６．共著：血管の収縮・弛緩と神経、腎と透析、1990
７．高血圧治療の実際−降圧薬のまとめ、医薬ジャーナル社、1991
８．共著：臨床講義−褐色細胞腫、臨床と研究、1991
９．共著：レニン阻害薬、臨床科学、1992
１０．降圧薬一覧表、医薬ジャーナル社、1993
１１．高血圧治療の実際−降圧薬のまとめ、医薬ジャーナル社、1994
１２．血圧変動性の評価、フジメディカル出版、1999
１３．小児の高血圧、フジメディカル出版、1999
１４．腎機能検査、真興交易医書出版部、2010
１５．腎臓が悪くても妊娠できる？、真興交易医書出版部、2010