開道 貴信 かいどう たかのぶ 先生

来歴等

略歴

1995年 奈良県立医科大学医学部卒業
1997年 奈良県立医科大学大学院医学研究科（病理学・外科学）入学
1999年 ドイツ・マインツ大学神経病理学教室（Oliver Kempski教授）留学
2001年 奈良県立医科大学大学院医学研究科 修了
2002年 医学博士取得
1995年 奈良県立医科大学脳神経外科教室 研修医
1996年 奈良県立奈良病院脳神経外科 研修医
1996年 町立大淀病院脳神経外科 医員
1997年 国立大阪南病院　脳神経外科レジデント
1998年 奈良県立医科大学脳神経外科 非常勤医師・大学院生
2001年 国立療養所西奈良病院脳神経外科及び国立奈良病院脳神経外科 併任
2003年 奈良県立五條病院脳神経外科 医員
2004年 町立大淀病院脳神経外科 医長
2005年 国立精神･神経センター武蔵病院脳神経外科 医師
2008年 Trainee, Advanced International Course: Bridging Basic with Clinical Epileptology-3International School of Neurological Sciences of Venice – Venice International University (International League against Epilepsy – European Epilepsy Academy), Venice, Italy（てんかん学）留学
2009年 Guest doctor: Centro Malattie Extrapiramidali e Sindrome di Tourette, Instituto Ortopedico Galeazzi, Milan, Italy (Prof. Mauro Porta)
（トゥレット症候群及びパーキンソン病など運動異常症に対する脳深部刺激療法）留学
2013年-2017年 国立精神・神経医療研究センター病院脳神経外科 医長
2017年 奈良医療センター

論文

Kaido T, Nakase H, Uranishi R, Sakaki T: Anomalous internal carotid artery in a patient with pituitary adenoma. J Neurosurg 91:710, 1999
Kaido T, Nakase H, Nagata K, Otsuka H, Sakaki T: Intermittent isometric exposure prevents brain retraction injury under venous circulatory impairment. Neurol Res 23: 739-744, 2001
Kaido T, Hoshida T, Uranishi R, Akita N, Kotani A, Nishi N, Sakaki T: Radiosurgery-induced brain tumor. J Neurosurg 95: 710-713, 2001
Kaido T, Okazaki A, Kurokawa SI, Tsukamoto M: Pathogenesis of intraparenchymal epidermoid cyst in the brain. Surg Neurol 59: 211-216, 2003
Kaido T, Nakase H, Goda K, Shin Y, Aoyama N, Sakaki T: Value of 3D CTA in association with accessory anterior cerebral artery with ruptured anterior communicating artery aneurysm. Acta Neurochir 145: 157-158, 2003
Kaido T, Uemura H, Hirao Y, Uranishi R, Nishi N, Sakaki T: Brain metastases from urachal carcinoma. J Clin Neurosci 10: 703-5, 2003
Kaido T, Sasaoka Y, Hashimoto H, Taira K: De Novo Germinoma in the Brain in Association with Klinefelter Syndrome. Surg Neurol 60: 553-558, 2003

Kaido T, Heimann A, Kempski O: Novel C1 Inhibitor BSF468248 does not improve brain damage after cortical vein occlusion. Methods Find Exp Clin Pharmacol 25: 611-616, 2003
Kaido T, Hoshida T, Taoka T, Sakaki T: Retinotopy with Coordinates of Lateral Occipital Cortex in Humans. J Neurosurg 101: 114-118, 2004
Kaido T, Hashimoto H, Okamura H, Tsukaguchi K: Progressive Severe Anemia due to Copper Deficiency Five Years after Subarachnoid Hemorrhage. J Clin Neurosci 12: 205-6, 2005
Kaido T, Otsuki T, Nakama H, Kaneko Y, Kubota Y, Sugai K, Saito O. Complex behavioral automatism arising from insular cortex. Epilepsy Behav 8:315-9. 2006
Kaido T, Kim YK, Ueda K: Diagnostic and therapeutic considerations of sinus pericranii. J Clin Neurosci 13:788-92. 2006
Kaido T, Tanaka Y, Kanemoto Y, Katsuragi Y, Okura H: Traumatic oculomotor nerve palsy. J Clin Neurosci 13:852-5. 2006
Kaido T, Otsuki T, Nakama H, Kaneko Y. Hypermotor seizure arising from insular cortex. Epilepsia 47. 1587-8. 2006
Kaido T. Response for “The second case of de novo intracranial germinoma association with Klinefelter's syndrome”. Surg Neurol 66:332. 2006
Nakayama T, Otsuki T, Kaneko Y, Nakama H, Kaido T, Otsubo H, Nakagawa E, Sasaki M, Sugai K.: Repeat magnetoencephalography and surgeries to eliminate atonic seizures of non-lesional frontal lobe epilepsy. Epilepsy Res 2-3. 263-7. 2009
Sato K, Nakagawa E, Saito Y, Komaki H, Sakuma H, Sugai K, Sasaki M, Kaido T, Nakama H, Otsuki T.: Hyperkinetic movement disorder in a child treated by globus pallidus stimulation. Brain Dev 31. 452-5. 2009
Kaido T, Otsuki T, Kaneko Y, Takahashi A, Kakita A, Takahashi H, Saito Y, Nakagawa E, Sugai K, Sasaki M: Anterior striatum with dysmorphic neurons associated with the epileptogenesis of focal cortical dysplasia. Seizure 19, 256-259. 2010
Kaido T, Noda T, Otsuki T, Kaneko Y, Takahashi A, Nakai T, Nabatame M, Tani M: Titanium alloys as fixation device material for cranioplasty and its safety in electroconvulsive therapy. J ECT 27. e27-8. 2011

Kaido T, Otsuki T, Kaneko Y, Takahashi A, Omori M, Okamoto T. Deep brain stimulation for Tourette syndrome: A prospective pilot study in Japan. Neuromodulation 14. 123-129. 2011
Kaido T, Moriyama Y, Ueda K, Higashiura W, Sakaguchi H, Kichikawa K: Recurrent brain abscess induced by pulmonary arteriovenous fistula. J Infect Chemother 17. 552-554. 2011
Kaido T, Otsuki T, Takahashi A, Kaneko Y. Epileptic Activity in Mesial Frontal Cortex in Nocturnal Paroxysmal Dystonia. Sleep Biol Rhythms 9. 188–191. 2011
Yonekawa T, Nakagawa E, Takeshita E, Inoue Y, Inagaki M, Kaga M, Sugai K, Sasaki M, Kaido T, Takahashi A, Otsuki T: Effect of corpus callosotomy on attention deficit and behavioral problems in pediatric patients with intractable epilepsy. Epilepsy Behav 22. 697-704. 2011
Kaido T, Heimann A, Kempski O: Neuronal immunoreactivity for mannose-binding lectin after venous occlusion-induced focal cerebral ischemia in rats. Neurol Psychiatr Brain Res 18. 129-135. 2012
Kaido T, Kempski O, Heimann A, Heers C, Bartsch D: Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. Turk Neurosurg 22. 441-7. 2012
Kaido T, Otsuki T, Kakita A, Sugai K, Saito Y, Sakakibara T, Takahashi A, Kaneko Y, Saito Y, Takahashi H, Honda R, Nakagawa E, Sasaki M, Ito M: Novel pathological abnormalities of deep brain structures including dysplastic neurons in anterior striatum associated with focal cortical dysplasia in epilepsy. J Neurosurg Pediat 10. 217-25. 2012
Kaido T, Otsuki T, Ogawa M, Takahashi A, Kaneko Y. Yamamoto T, Nakata Y: Medullary ischemia due to vertebral arteritis associated with Behçet syndrome: a case report. Asian Pac J Allergy Immunol 30. 239-242. 2012
Irahara K, Nakagawa E, Honda R, Sugai K, Sasaki M, Kaido T, Kaneko Y, Takahashi A, Otsuki T: High gamma activity in the area surrounding a cortical tuber in an infant with tuberous sclerosis. Italian Journal of Pediatrics 38. 15. 2012
Yanase M, Kaido T, Yamada M, Watanabe M: Malformations of cortical development with good clinical outcome – a case report and review of literature. BMJ case rep 2012. Jun 28 (epub). 2012

Sakakibara T, Sukigara S, Saito T, Otsuki T, Takahashi A, Kaneko Y, Kaido T, Saito Y, Sato N, Kimura Y, Nakagawa E, Sugai K, Sasaki M, Goto Y, Itoh M: Delayed Maturation and Differentiation of Neurons in Focal Cortical Dysplasia With the Transmantle Sign: Analysis of Layer-Specific Marker Expression. J Neuropathol Exp Neurol 71. 741-9 .2012
Arai A, Saito T, Hanai S, Sukigara S, Nabatame S, Otsuki T, Nakagawa E, Takahashi A, Kaneko Y, Kaido T, Saito Y, Sugai K, Sasaki M, Goto Y, Itoh M: Abnormal maturation and differentiation of neocortical neurons in epileptogenic cortical malformation: Unique distribution of layer-specific marker cells of focal cortical dysplasia and hemimegalencephaly. Brain Res 1470. 89-97. 2012
Sakakibara T, Sukigara S, Otsuki T, Takahashi A, Kaneko Y, Kaido T, Saito Y, Sato N, Nakagawa E, Sugai K, Sasaki M, Goto Y, Itoh M.: Imbalance of interneuron distribution between neocortex and basal ganglia: consideration of epileptogenesis of focal cortical dysplasia. J Neurol Sci 323. 128-33. 2012
Saito T, Saito Y, Sugai K, Nakagawa E, Komaki H, Okazaki T, Ishido Y, Kaneko Y, Kaido T, Takahashi A, Ohtsuki T, Sakuma H, Sasaki M.: Late-onset epilepsy in children with acute febrile encephalopathy with prolonged convulsions: A clinical and encephalographic study. Brain Dev 35. 531-9. 2013
Liang QC, Otsuki T, Takahashi A, Enokizono T, Kaido T, Kaneko Y, Nakagawa E, Sugai K, Sasaki M: Posterior Disconnection in Early Infancy to Treat Intractable Epilepsy with Multilobar Cortical Dysplasia. Three cases series. Neurol Med Chir (Tokyo) 53. 47-52. 2013
Otsuki T, Honda R, Takahashi A, Kaido T, Kaneko Y, Nakai T, Saito Y, Itoh M, Nakagawa E, Sugai K, Sasaki M.: Surgical management of cortical dysplasia in infancy and early childhood. Brain Dev 35. 802-9. 2013
Honda R, Kaido T*, Sugai K, Takahashi A, Kaneko Y, Nakagawa E, Sasaki M, Otsuki T: Long-term developmental outcome after early hemispherotomy for hemimegalencephaly in infants with epileptic encephalopathy. Epilepsy Behav 29. 30-5. 2013 (*corresponding author)
Sukigara S, Dai H, Nabatame S, Otsuki T, Hanai S, Honda R, Saito T, Nakagawa E, Kaido T, Sato N, Kaneko Y, Takahashi A, Sugai K, Saito Y, Sasaki M, Goto Y, Koizumi S, Itoh M: Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy. J Neuropathol Exp Neurol 73. 798-806. 2014
Endo Y, Saito Y, Otsuki T, Takahashi A, Nakata Y, Okada K, Hirozane M, Kaido T, Kaneko Y, Takada E, Okazaki T, Enokizno T, Saito T, Komaki H, Nakagawa E, Sugai K, Sasaki M: Persistent verbal and behavioral deficits after resection of the left supplementary motor area in epilepsy surgery. Brain Dev 36. 74-9. 2014
Schrock LE, Mink JW, Woods DW, Porta M, Servello D, Visser-Vandewalle V, Silburn PA, Foltynie T, Walker HC, Shahed-Jimenez J, Savica R, Klassen BT, Machado AG, Foote KD, Zhang JG, Hu W, Ackermans L, Temel Y, Mari Z, Changizi BK, Lozano A, Auyeung M, Kaido T, Agid Y, Welter ML, Khandhar SM, Mogilner AY, Pourfar MH, Walter BL, Juncos JL, Gross RE, Kuhn J, Leckman JF, Neimat JA, Okun MS; Tourette Syndrome Association International Deep Brain Stimulation (DBS) Database and Registry Study Group: Tourette syndrome deep brain stimulation: A review and updated recommendations. Mov Disord 30. 448-71. 2015
Puentes S, Kaido T, Hanakawa T, Ichinohe N, Otsuki T, Seki K: Internal capsule stroke in the common marmoset. Neuroscience 284. 400-11. 2015

その他

• 【受賞】2007年　第41回日本てんかん学会　優秀ポスター賞

• 【受賞】2008年　日本てんかん学会Sponsored Award（UCB賞）

• 【受賞】2008年　日本てんかん学会JES Award （「てんかん研究」誌最優秀論文賞）