髙橋 達 たかはし とおる 先生

来歴等

略歴

1977年　秋田大学医学部卒業
1988年　医学博士（新潟大学）
1990年　米国マウントサイナイ医科大学留学
1992年　新潟大学医学部第3内科助手
2002年　同講師
2003年　長岡赤十字病院消化器内科部長
2010年　新潟県厚生連魚沼病院病院長
2017年　新潟県厚生連小千谷総合病院病院長

論文

1) Yamagiwa S, Ishikawa T, Waguri N, Sugitani S, Wakabayashi H, Ohkoshi S, Tsukishiro T, Takahashi T, Watanabe T, Terai S. Efficacy and Safety of telaprevir- and simeprevir-based triple therapies for elder patients with chronic hepatitis C. World Journal of Hepatol 2017; 18; 9(5): 252-262.

2) Takahashi T. Interleukin 28B genetic polymorphism and hepatitis B virus infection. World Journal of Gastroenterol 2014; 20(34): 12026-12030.

3) Yang C-Y, Ma X, Tsuneyama K, Huang S, Takahashi T, Chalasani NP, Bowlus CL, Yang G-X, Leung PSC, Ansari AA, Wu L, Coppel R, Gershwin ME. IL-12/Th1 and IL23/Th17 biliary microenvironment in primary biliary cirrhosis: implication for therapy. Hepatology 2014; 59: 1944-1953.

4) Takahashi T, Miura T, Nakamura J, Yamada S, Miura T, Yanagi M, Matsuda Y, Usuda H, Emura I, Tsuneyama K, He X-S, Gershwin ME. Plasma cells and the chronic nonsuppurative destructive cholangitis of primary biliary cirrhosis. Hepatology 2012; 55：846-85.

5) Takahashi T, Koike T, Hashimoto S, Miura T, Nakamura J, Yamada S, Miura T, Yanagi M, Yamazaki K, Okoshi S, Aoyagi Y. A case of lamivudine-sensitive de novo acute hepatitis B induced by rituximab with the CHOP regimen for diffuse large B cell lymphoma. Hepatology International 2009; 3: 316-322.

6) Kawai H, Suda T, Aoyagi Y, Isokawa O, Mita Y, Waguri N, Kuroiwa T, Igarashi M, Tsukada K, Mori S, Shimizu T, Suzuki Y, Abe Y, Takahashi T, Nomoto M, Asakura H. Quantitative evaluation of genomic instability as a possible predictor for development of hepatocellular carcinoma: comparison of loss of heterogeneity and replication error. Hepatology 2000; 31: 1246-1250.

7) Takahashi T, So-wan T, Kamimura T, Asakura H. Infiltrating polymorphonuclear leukocytes and apoptotic bodies derived from hepatocytes but not from ballooning hepatocytes containing Mallory bodies show nuclear DNA fragmentation in alcoholic hepatitis. Alcoholism: Clin Exp Res 2000; 24: 68S-73S.

8) Yokota T, Suda T, Tsukioka S, Takahashi T, Honma T, Seki K, Matsuzawa J, Miura M, Aoyagi Y, Asakura H. The striking effect of hyperbaric oxygenation therapy in the management of chronic idiopathic intestinal pseudo-obstruction. Am J Gastroenterol 2000; 95: 285-288.

9) Isokawa O, Suda T, Aoyagi Y, Kawai H, Yokota T, Takahashi T, Tsukada K, Shimizu T, Mori S, Abe Y, Suzuki Y, Nomoto M, Mita Y, Yanagi M, Igarashi H, Asakura H. Reproduction of telomeric repeats as a possible predictor for development of hepatocellular carcinoma: convenient evaluation by slot-blot analysis. Hepatology 1999; 30: 408-412.

10) Suda T, Isokawa O, Aoyagi Y, Nomoto M, Tsukada K, Shimizu T, Suzuki Y, Naito A, Igarashi H, Yanagi M, Takahashi T, Asakura H. Quantitation of telomerase activity in hepatocellular carcinoma: A possible aid for a prediction of recurrent diseases in the remnant liver. Hepatology 1998; 27: 402-406.

11) Takahashi T, Isemura M, Nakamura T, Matsui S, Oyanagi Y, Asakura H. Immunolocalization of a fibronectin-binding proteoglycan (PG-P1) immunologically related to HSPG2/perlecan in normal and fibrotic human liver. J Hepatol 1994; 21: 500-508.

12) Takahashi T, Lasker JM, Rosman AS, Lieber CS. Induction of cytochromeP4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology 1993; 17: 236-245.

13) Takahashi T, Kamimura T, Asakura H, Ichida F. Hepatic lesions in alcoholic HBV carriers. Dig Dis Sci 1991; 36: 1234-1242.

14) Takahashi T, Kamimura T, Ichida F. Ultrastructural findings on polymorphonuclear leucocyte infiltration and acute hepatocellular damage in alcoholic hepatitis. Liver 1987; 7: 347-358.

その他

• 【受賞】 1992年　GLAXO Research Institute Fellow’s Award