片山 和宏 かたやま かずひろ 先生

来歴等

略歴

1981年 大阪大学医学部 卒業
1981年 大阪大学医学部附属病院 研修医
1983年 大阪大学医学部 放射線科　
1984年 大阪大学医学部 第一内科　
1997年 大阪厚生年金病院 内科 医長
1999年 同上 内科 部長（消化器担当）
2006年 同上 内科 主任部長
2009年 大阪府立成人病センター 肝胆膵内科 主任部長
2014年 同上 副院長、臨床研究センター長
2017年 大阪国際がんセンター 副院長、臨床研究センター長
2019年 同上 副院長、臨床研究管理センター所長
2020年 貝塚市病院事業管理者に就任／市立貝塚病院 総長

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論文

• 1. Possible role of ammonia in liver cirrhosis without hyperammonemia of venous blood: The so-called latency period of abnormal ammonia metabolism. Hepatol Res 2024;54:235-243.

  Kazuhiro Katayama, Naruyasu Kakita.

• 2. Zinc transporter 1 expression in hepatocellular carcinoma correlates with prognosis: A single-center retrospective study. J Trace Elem Med Biol 2024;82:127354.

  Naruyasu Kakita, Kazuhiro Katayama, Toshifumi Yasui, Shin Satake, Kenji Aoi, Hisashi Jo, Yong Kook Kim, Masaru Yamazaki, Ayako Hashimoto, Taiho Kambe.

• 3. Clinical significance of the latency period of abnormal ammonia metabolism in chronic liver disease: Proposal of a new concept. Hepatol Res 2022;52:75-80.

  Katayama K.

• 4. Efficacy and safety of modified fluorouracil/leucovorin plus irinotecan and oxalipltin (mFOLFIRINOX) compared with S-1 as second-line chemotherapy in metastatic pancreatic cancer. JGH Open 2021:1-7.

  Ikezawa K, Kiyota R, Takada R, Daiku K, Maeda S, Imai T, Abe Y, Kai Y, Yamai T, Fukutake N, Nakabori T, Ashida R, Uehara H, Tabuchi T, Katayama K, Ohkawa K.

• 5. Predictive factors for pancreatic cancer and its early detection using special pancreatic ultrasonography in high-risk individuals. Cancers 2021;13:502.

  Fukuda J, Ikezawa K, Nakao M, Okagaki S, Ashida R, Ioka T, Takada R, Yamai T, Fukutake N, Uehara H, Nagata S, Takahashi H, Tabuchi T, Tanaka S, Ohkawa K, Katayama K.

• 6. Effectiveness of contrast-enhanced ultrasonography for the characterization of small and early stage pancreatic adenocarcinoma. Ultrasound in Med & Biol. 2020;46(9):2245-2253.

  Sachiko Tanaka, Junko Fukuda, Miho Nakao, Tatsuya Ioka, Reiko Ashida, Rena Takakura, Suetsumi Okagaki, Kazuhiro Katayama, Kazuyoshi Ohkawa, Kenji Ikezawa, Shigenori Nagata.

• 7. Japan’s practical guideline for zinc deficiency with a particular focus on taste disorders, inflammatory bowel disease, and liver cirrhosis. Int J Mol Sci 2020;21:2941.

  Kodama H, Tanaka M, Naito Y, Katayama K, Moriyama M.

• 8. Prognostic factors for patients with a large number of hepatocellular carcinoma nodules. J Clin Med Res 2020;12(1):26-35.

  Abe Y, Ohkawa K, Sakakibara M, Nawa T, Fukutake N, Ikezawa K, Takada R, Kusakabe A, Imai T, Nakanishi K, Tabuchi T, Hikita H, Sakamori R, Tatsumi T, Takehara T, Katayama K.

• 9. Zinc and protein metabolism in chronic liver diseases. Nutr Res 2020;74:1-9.

  Katayama K. (Review article)

• 10. Chemotherapy-induced sclerosing cholangitis caused by systemic chemotherapy. ACG Case Rep J. 2019 Jul 17;6(7)

  Kusakabe A, Ohkawa K, Fukutake N, Sakakaibara M, Imai T, Abe Y, Takada R, Ikezawa K, Nawa T, Ashida R, Kimura T, Nagata S, Katayama K.

• 11. Effects of zinc acetate on serum zinc concentrations in chronic liver diseases: a multicenter, double-blind, randomized, placebo-controlled trail and a dose adjustment trial. Biological Trace Element Research. 2020(May);195(1):71-81

  Katayama K, Hosui A, Sakai Y, Itou M, Matsuzaki Y, Takamori Y, Hosho K, Tsuru T, Takikawa Y, Michitaka K, Ogawa E, Miyoshi Y, Ito T, Ida S, Hamada I, Miyoshi K, Kodama H, Takehara T.

• 12. Development of a thrombus in the superior mesenteric artery associated with sequential therapy with tyrosine kinase inhibitors for hepatocellular carcinoma. Clin J Gastroenterol 2020;13(2):247-251.

  Nawa T, Katayama K, Kiyota R, Imai T, Abe Y, Hasegawa N, Takada R, Fukutake N, Ikezawa K, Sakakibara M, Fujita M, Ohkawa K.

• 13. Hypozincemia is associated with human hepatocarcinogenesis in hepatitis C virus-related liver cirrhosis. Hepatol Res 2019;49:1127-1135.

  Shigefuku R, Iwasa M, Katayama K, Eguchi A, Kawaguchi T, Shiraishi K, Ito T, Suzuki K, Koreeda C, Ohtake T, Tokumoto Y, Endo R, Kawamura N, Shiraki M, Habu D, Sakai H, Kato A, Nishiguchi S, Moriwaki H, Suzuki K, Takei Y.

• 14. Incidence and risk factors of hepatocellular carcinoma change over time in HCV patients who achieved sustained virologic response. Hepatol Res 2019 May;49(5):570-578.

  Yamada R, Hiramatsu N, Oze T, Urabe A, Tahata Y, Morishita N, Kodama T, Hikita H, Sakamori R, Yakushijin T, Yamada A, Hagiwara H, Mita E, Oshita M, Itoh T, Fukui H, Inui Y, Hijioka T, Inada M, Katayama K, Tamura S, Inoue A, Imai Y, Tatsumi T, Hamasaki T, Hayashi N, Takehara T.

• 15. Factors affecting therapeutic effects in 17 patients with advanced hepatocellular carcinoma who were treated with Sorafenib for more than 12 months. Case Rep Oncol 2018;11:711-720.

  Kazuhiro Katayama, Ryosuke Kiyota, Toshihiro Imai, Yutaro Abe, Tadatoshi Nawa, Hiroshi Wada, Kazuyoshi Ohkawa.

• 16. Number of nodules but not size of hepatocellular carcinoma can predict refractriness to transarterial chemoembolization and poor prognosis. J Clin Med Res. 2018;10(10):765-771.

  Kazuhiro Katayama, Toshihiro Imai, Yutaro Abe, Tadatoshi Nawa, Noboru Maeda, Katsuyuki Nakanishi, Hiroshi Wada, Keisuke Fukui, Yuri Ito, Isao Yokota, Kazuyoshi Ohkawa.

• 17. To the Editor: Clinical features and prognosis of patients with the bone metastasis of pancreatic cancer. A single-institutional cohort study. Pancreas 47(7):e43-e46, 2018.

  Hidetatsu Outani, Hirofumi Akita, Takaaki Nakai, Ryoji Takada, Yoshinori Imura, Takaaki Tanaka, Hironari Tamiya, Kazuya Oshima, Hidenori Takahashi, Kazuyoshi Ohkawa, Kazuhiro Katayama, Nobuhito Araki, Norifumi Naka.

• 18. The prevalence and implication of zinc deficiency in patients with chronic liver disease. J Clin Med Res 2018;10(5):437-444.

  Kazuhiro Katayama, Takumi Kawaguchi, Koichi Shiraishi, Toshifumi Ito, Kazutomo Suzuki, Chizu Koreeda, Takaaki Ohtake, Motoh Iwasa, YoshioTokumoto, Ryujin Endo, Naohiro Kawamura, Makoto Shiraki, Tatsunori Hanai, Daiki Habu, Satoru Tsuruta, Hironori Sakai, Yoshiyuki Miwa, Norifumi Kawada, Akinobu Kato, Yoshiyuki Takei, Tetsuya Mine, Yutaka Kohgo, Toshihito Seki, Michio Sata, Yuri Ito, Keisuke Fukui, Shuhei Nishiguchi, Hisataka Moriwaki, Kazuyuki Suzuki.

• 19. Selective identification of somatic mutations in pancreatic cancer cells through a combination of next-generation sequencing of plasma DNA using molecular barcodes and a bioinformatics variant filter. PLoS ONE 13(2):e0192611.

  Yoji Kukita, Kazuyoshi Ohkawa, Ryoji Takada, Hiroyui Uehara, Kazuhiro Katayama, Kikuya Kato.

• 20. A case of stage IA pancreatic ductal adenocarcinoma accompanied with focal pancreatitis demonstrated by contrast-enhanced ultrasonography. J Med Ultrason 2018;45:617-622.

  Fukuda J, Tanaka S, Ishida N, Ioka T, Ikezawa K, Takakura R, Nakao M, Ohkawa K, Katayama K, Nagata S.

• 21. Two-step progression of varenicline-induced autoimmune hepatitis. Clin J Gastroentrol 2018;11(3):184-187.

  Sakakibara M, Ohkawa K, Nawa T, Abe Y, Kusakabe A, Imai T, Katayama K.

• 22. Prospective comparison of Gd-EOB-DTPA-enhanced MRI with Dynamic CT for detecting recurrence of HCC after radiofrequency ablation. Liver Cancer 2017;6:349-359.

  Imai Y, Katayama K, Hori M, Yakushijin T, Fujimoto K, Itoh T, Igura T, Sakakibara M, Takamura M, Tsurusaki M, Takahashi H, Nakanishi K, Usuki M, Tsuji K, Ohashi H, Kim T, Takehara T, Murakami T.

• 23. Evaluating the ability to detect pancreatic lesions using a special ultrasonography examination focusing the pancreas. Eur J Radiol 2017;91:10-14.

  M Nakao, K Katayama, J Fukuda, S Okagaki, K Misu, S Miyazaki, N Matsuno, R Ashida, T Ioka, Y Ito, K Ohkawa.

• 24. The effectiveness of a liver disease education class for providing information to patients and their families. J Clin Med Res 2017;9(3):207-212.

  Kadokawa Y, Katayama K, Takahashi K, Fukushima N, Tanaka S, Taniguchi Y, Nawa T, Sakakibara M, Ohkawa K.

• 25. Subclassification of patients with intermediate-stage (Barcelona Clinic Liver Cancer stage-B) hepatocellular carcinoma using the up-to-seven criteria and serum tumor markers.　Hepatol Int, 2017;11(1):105-114.

  Kimura H1, Ohkawa K2, Miyazaki M1, Sakakibara M1, Imanaka K1, Tamura T1, Sueyoshi H1, Takada R1, Fukutake N1, Uehara H1, Ashida R3, Ioka T3, Nakazawa T4, Nakanishi K4, Katayama K1,3.

• 26. A novel multivariate index for pancreatic cancer detection based on the plasma free amino acid profile. PLoS ONE 10(7):e0132223.

  Nobuyasu Fukutake, Makoto Ueno, Nobuyoshi Hiraoka, Kazuaki Shimada, Koichi Shiraishi, Nobuhiro Saruki, Toshifumi Ito, Minoru Yamakado, Nobukazu Ono, Akira Imaizumi, Shinya Kikuchi, Hiroshi Yamamoto, Kazuhiro Katayama.

• 27. Factors related to shift from hepatic borderline lesion to overt HCC diagnosed by CT. Hepatogastroenterology 2014; 61: 1680-7.

  Ohkawa K, Imanaka K, Sakakibara M, Tamai C, Ishihara A, Hasegawa N, Kawada N, Yamai T, Sakai A, Fukutake N, Uehara H, Nakanishi K, Katayama K.

• 28. Effect of zinc on liver cirrhosis with hyperammonemia: A preliminary randomized, placebo-controlled double-blind trial. Nutrition 2014;30:1409-1414.

  Kazuhiro Katayama, Masanori Saito, Takumi Kawaguchi, Ryujin Endo, Kei Sawara, Shuhei Nishiguchi, Akinobu Kato, Hiroshi Kohgo, Kazutomo Suzuki, Isao Sakaida, Yoshiyuki Ueno, Daiki Habu, Toshifumi Ito, Hisataka Moriwaki, Kazuyuki Suzuki.

• 29. Three-dimensional registration of images obtained before and after radiofrequency ablation of hepatocellular carcinoma to assess treatment adequency. AJR 2014 May;205(5):W487-95.

  Sakakibara M, Ohkawa K, Katayama K, Imanaka K, Ishihara A, Hasegawa N, Kimura H.

• 30. Branched-chain Amino Acids Prevent Hepatocarcinogenesis and Prolong Survival of Patients with Cirrhosis. Clin Gastroenterol Hepatol. 2014 Jun;12(6):1012-1018.

  Kawaguchi T, Shiraishi K, Ito T, Suzuki K, Koreeda C, Ohtake T, Iwasa M, Tokumoto Y, Endo R, Kawamura NH, Shiraki M, Habu D, Tsuruta S, Miwa Y, Kawaguchi A, Kakuma T, Sakai H, Kawada N, Hanai T, Takahashi SI, Kato A, Onji M, Takei Y, Kohgo Y, Seki T, Tamano M, Katayama K, Mine T, Sata M, Moriwaki H, Suzuki K.

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著書

• 1. 片山和宏 編集／やさしいウイルス性慢性肝炎の自己管理／医薬ジャーナル社／2007年。

• 2. 片山和宏 編集／肝硬変の本／昌栄印刷／2010年。

• 3. 片山和宏 III栄養学的介入 ３亜鉛。 西口修平 編集／肝硬変のマネージメント／医薬ジャーナル社／2016年。

• 4. 片山和宏 ６消化器疾患・肝胆膵疾患 ４肝硬変。井村裕夫　編集主幹／わかりやすい内科学／文光堂／2023年。

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受賞

• 1. 片山和宏。Effects of alpha-interferon on gamma-interferon production of peripheral blood mononuclear cells in hepatitis B virus carriers. 1993年度日本肝臓学会研究奨励賞。

• 2. 片山和宏。肝細胞及び肝癌細胞の細胞増殖、癌化における肝細胞増殖因子の肝細胞増殖因子受容体を介した細胞内情報伝達系の検討。平成5年度（1993年度）大阪対がん協会 がん研究助成奨励金

• 3. 片山和宏。肝硬変の窒素代謝における亜鉛の意義および亜鉛補充療法の有用性についての検討。第4回 Ajinomoto Award（2002年）

その他

• 【テレビ出演】

• 1. 羽鳥慎一モーニングショー 2021年9月7日

• 2. ミヤネ屋 2021年9月9日

• 3. 健康カプセル 元気の時間 2022年4月3日

• 4. 健康カプセル 元気の時間 2016年11月13日

• 5. ためしてガッテン 2015年5月20日

• 6. おはよう ドクター 2019年5月25日

• 7. 毎日放送 医のココロ 2019年11月16日

• 【マスコミ】

• 1. 週刊ゲンダイ 2017年5月23日

• 2. 毎日新聞 2017年5月25日

• 3. Asahi Shinbun Weekly AERA 2015年9月７日

• 4. 週刊文春 2017年1月26日

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