渡邉 哲 先生のプロフィール

渡邉 哲 先生

わたなべ てつ

渡邉 哲 先生

山形大学医学部附属病院 第一内科 循環器内科

専門分野

循環器内科

紹介

山形大学医学部附属病院第一内科の循環器内科にて講師/病院教授をつとめ、研究面では動脈硬化、心不全、急性心筋梗塞の疫学、心エコー、突然死などの研究に力を入れている。山形大学医学部附属病院では心臓に関するほぼすべての病気に関して診断、治療を行える設備を備えており、循環器内科の全てのスタッフが冠動脈インターベンション(PCI)を行い、それぞれの専門分野にとらわれない診療を展開している。こうした体制を持つことから、幅広い知識と技術をもつ循環器医の育成にも力を入れている。

略歴

1994年    山形大学医学部附属病院 医員(研修医)
1995年    石巻赤十字病院 内科勤務(研修医)
2000年    山形大学医学部附属病院 医員
        山形大学医学部附属病院 助手(第一内科)
        公立置賜総合病院 内科勤務
2002年    山形大学医学部附属病院 助手(第一内科)
2003年    米国ロチェスター大学 心血管研究所(ポスドク)
2005年    山形大学医学部附属病院 助手(第一内科)
2007年  山形大学医学部附属病院 助教(第一内科)
2008年  山形大学医学部附属病院 講師(第一内科)
2010年    山形大学医学部附属病院 病院教授(第一内科)
現在に至る

所属学会・資格・役職など

【資格】
日本内科学会(総合内科専門医・指導医)
日本循環器学会(循環器専門医)
日本高血圧学会(専門医)
日本超音波医学会(専門医・指導医)
日本動脈硬化学会 (専門医)

【所属学会・委員会】
日本内科学会
日本循環器学会 評議員(社員) 2008年~
日本心臓病学会 FJCC 2011年~ 評議員 2013年~
日本不整脈心電学会
日本高血圧学会
日本動脈硬化学会
日本超音波医学会
日本心エコー図学会
日本心不全学会
日本心血管インターベンション治療学会
日本心臓リハビリテーション学会
国際心臓研究学会(ISHR) 日本部会 評議員 2012年~
米国心臓病協会(AHA)
米国心エコー学会(ASE)
欧州心臓病学会(ESC) FESC 2017年~

受賞・著書・論文など

【著書】
1. 赤塚宣治,池亀俊美,犬尾千聡,加藤貴康,北濱真理子,松田真紀子,真野響子,森下幸治,渡邉哲 監修:看護師・看護学生のためのなぜ?どうして? ②成人看護 循環器・血液・免疫(第6版).メディックメディア(東京)2015.
2. 渡邉哲:分子標的治療における高血圧対策・心機能対策.冨田善彦編.すぐ使える医師・看護師・薬剤師・CRCのための分子標的薬トータルマネージメント[第2版].リッチヒルメディカル㈱(東京)2015. p15-19.
3. 渡邉哲,久保田功:XⅥ その他 7.心臓病と肥満:メタボリックシンドロームを中心に.堀正二,永井良三編集.循環器疾患最新の治療2014-2015.南江堂(東京)2014. p424-426.
4. 渡邉哲,久保田功: Brugada症候群.堀正二,永井良三編集.循環器疾患最新の治療2012-2013.南江堂(東京)2012. p349-351.
5. 渡邉哲,久保田功:第4章.各疾患のみかたと対応 D.虚血性心疾患 2.急性冠症候群 ⑨心筋梗塞の長期予後と再発防止.永井良三総監修,川名正敏,許俊鋭,長谷川昭,広井透雄,三田村秀雄,山下武志編.循環器研修ノート.診断と治療社(東京)2010. p571-573.
6. 渡邉哲,久保田功:不整脈 脚ブロック.友池仁暢総編集. 最新循環器診療マニュアル.中山書店(東京)200

【著書】
1. 赤塚宣治,池亀俊美,犬尾千聡,加藤貴康,北濱真理子,松田真紀子,真野響子,森下幸治,渡邉哲 監修:看護師・看護学生のためのなぜ?どうして? ②成人看護 循環器・血液・免疫(第6版).メディックメディア(東京)2015.
2. 渡邉哲:分子標的治療における高血圧対策・心機能対策.冨田善彦編.すぐ使える医師・看護師・薬剤師・CRCのための分子標的薬トータルマネージメント[第2版].リッチヒルメディカル㈱(東京)2015. p15-19.
3. 渡邉哲,久保田功:XⅥ その他 7.心臓病と肥満:メタボリックシンドロームを中心に.堀正二,永井良三編集.循環器疾患最新の治療2014-2015.南江堂(東京)2014. p424-426.
4. 渡邉哲,久保田功: Brugada症候群.堀正二,永井良三編集.循環器疾患最新の治療2012-2013.南江堂(東京)2012. p349-351.
5. 渡邉哲,久保田功:第4章.各疾患のみかたと対応 D.虚血性心疾患 2.急性冠症候群 ⑨心筋梗塞の長期予後と再発防止.永井良三総監修,川名正敏,許俊鋭,長谷川昭,広井透雄,三田村秀雄,山下武志編.循環器研修ノート.診断と治療社(東京)2010. p571-573.
6. 渡邉哲,久保田功:不整脈 脚ブロック.友池仁暢総編集. 最新循環器診療マニュアル.中山書店(東京)2009. p313-316.
7. 宮本卓也,渡邉哲,久保田功:運動負荷心電図の結果を鵜呑みにすることなかれ.山科章編.循環器検査のグノーティ・セアウトン.株式会社シナジー(東京)2009. p9-13.
8. 渡邉哲,久保田功:4. 甲状腺疾患と心臓.堀正二,永井良三編.循環器疾患最新の治療 2008-2009. 南江堂(東京)2008. p471-474.
9. 渡邉哲,久保田功:Ⅳ.高血圧治療の最前線をいく 4.薬物療法 心拍数を抑制するカルシウム拮抗薬の特徴とエビデンス.苅尾七臣,島田和幸,吉川純一,笠貫宏,土師一夫,別府慎太郎,松崎益徳編.新・心臓病診療プラクティス 11.高血圧を識る・個別診療に活かす.文光堂(東京)2008. p231-233.
10. 渡邉哲,久保田功:第2部 全身疾患と心血管異常 Ⅱ各疾患の診断と治療 ①内分泌疾患に伴う心疾患.井上博,増山理総編集.代田浩之編集.エキスパートをめざす循環器診療 6.先天性心疾患,全身疾患と心血管異常.南江堂(東京)2007. p238-246.

【論文】
1. Otaki Y, Watanabe T, Takahashi H, Yamaura G, Nishiyama S, Arimoto T, Shishido T, Miyamoto T, Kubota I. Serum carboxy-terminal telopeptide of type i collagen (i-ctp) is predictive of clinical outcome in peripheral artery disease patients following endovascular therapy. Heart Vessels. 2017;32:149-156
2. Otaki Y, Watanabe T, Kinoshita D, Yokoyama M, Takahashi T, Toshima T, Sugai T, Murase T, Nakamura T, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. Association of plasma xanthine oxidoreductase activity with severity and clinical outcome in patients with chronic heart failure. Int J Cardiol. 2017;228:151-157
3. Kadowaki S, Watanabe T, Otaki Y, Narumi T, Honda Y, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. Combined assessment of myocardial damage and electrical disturbance in chronic heart failure. World J Cardiol. 2017;9:457-465
4. Honda Y, Watanabe T, Shibata Y, Otaki Y, Kadowaki S, Narumi T, Takahashi T, Kinoshita D, Yokoyama M, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Inoue S, Miyamoto T, Konta T, Kawasaki R, Daimon M, Kato T, Ueno Y, Kayama T, Kubota I. Impact of restrictive lung disorder on cardiovascular mortality in a general population: The yamagata (takahata) study. International journal of cardiology. 2017
5. Hashimoto N, Arimoto T, Narumi T, Iwayama T, Kutsuzawa D, Ishigaki D, Kumagai YU, Tamura H, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Watanabe T, Kubota I. The neutrophil-to-lymphocyte ratio predicts all-cause mortality in patients with implantable cardioverter defibrillators. Pacing and clinical electrophysiology : PACE. 2017;40:135-144
6. Yokoyama M, Watanabe T, Otaki Y, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Konta T, Shibata Y, Daimon M, Ueno Y, Kato T, Kayama T, Kubota I. Association of the aspartate aminotransferase to alanine aminotransferase ratio with bnp level and cardiovascular mortality in the general population: The yamagata study 10-year follow-up. Dis Markers. 2016;2016:4857917
7. Watanabe T. Is the brain the alternative therapeutic target for heart failure? Circ J. 2016;80:1702-1703
8. Watanabe T. Here comes a novel heart-rate reducing therapy in heart failure treatment. Circ J. 2016;80:594-595
9. Wanezaki M, Watanabe T, Nishiyama S, Hirayama A, Arimoto T, Takahashi H, Shishido T, Miyamoto T, Kawasaki R, Fukao A, Kubota I. Trends in the incidences of acute myocardial infarction in coastal and inland areas in japan: The yamagata ami registry. J Cardiol. 2016;68:117-124
10. Sato H, Konta T, Ichikawa K, Suzuki N, Kabasawa A, Suzuki K, Hirayama A, Shibata Y, Watanabe T, Kato T, Ueno Y, Kayama T, Kubota I. Comparison of the predictive ability of albuminuria and dipstick proteinuria for mortality in the japanese population: The yamagata (takahata) study. Clin Exp Nephrol. 2016;20:611-617
11. Otaki Y, Watanabe T, Takahashi H, Yamaura G, Nishiyama S, Arimoto T, Shishido T, Miyamoto T, Kubota I. Serum carboxy-terminal telopeptide of type i collagen (i-ctp) is predictive of clinical outcome in peripheral artery disease patients following endovascular therapy. Heart vessels. 2016
12. Otaki Y, Watanabe T, Takahashi H, Yamaura G, Nishiyama S, Arimoto T, Shishido T, Miyamoto T, Kubota I. Renal tubular damage is associated with poor clinical outcome in patients with peripheral artery disease who underwent endovascular therapy. Int J Cardiol. 2016;220:376-381
13. Otaki Y, Watanabe T, Takahashi H, Funayama A, Kinoshita D, Yokoyama M, Takahashi T, Nishiyama S, Arimoto T, Shishido T, Miyamoto T, Konta T, Kubota I. Comorbid renal tubular damage and hypoalbuminemia exacerbate cardiac prognosis in patients with chronic heart failure. Clin Res Cardiol. 2016;105:162-171
14. Otaki Y, Watanabe T, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Konta T, Shibata Y, Sato H, Kawasaki R, Daimon M, Ueno Y, Kato T, Kayama T, Kubota I. The impact of superoxide dismutase-1 genetic variation on cardiovascular and all-cause mortality in a prospective cohort study: The yamagata (takahata) study. PLoS One. 2016;11:e0164732
15. Otaki Y, Takahashi H, Watanabe T, Funayama A, Netsu S, Honda Y, Narumi T, Kadowaki S, Hasegawa H, Honda S, Arimoto T, Shishido T, Miyamoto T, Kamata H, Nakajima O, Kubota I. Hect-type ubiquitin e3 ligase itch interacts with thioredoxin-interacting protein and ameliorates reactive oxygen species-induced cardiotoxicity. J Am Heart Assoc. 2016;5
16. Narumi T, Watanabe T, Iwayama T, Ichikawa K, Wanezaki M, Nishiyama S, Sadahiro M, Kubota I. Ruptured right sinus of valsalva aneurysm caused by suspected takayasu's arteritis. Internal Med. 2016;55:1305-1308
17. Kumagai YU, Arimoto T, Iwayama T, Hashimoto N, Watanabe T, Kubota I. Contact force-guided deep engagement with a steerable sheath in the distal great cardiac vein: A case report. Pacing Clin Electrophysiol. 2016;39:507-510
18. Kobayashi M, Shibata Y, Inoue S, Igarashi A, Sato K, Sato M, Nemoto T, Abe Y, Nunomiya K, Nishiwaki M, Tokairin Y, Kimura T, Daimon M, Makino N, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Predictors for mortality from respiratory failure in a general population. Scientific reports. 2016;6:26053
19. Kamei K, Konta T, Ichikawa K, Sato H, Suzuki N, Kabasawa A, Suzuki K, Hirayama A, Shibata Y, Watanabe T, Kato T, Ueno Y, Kayama T, Kubota I. Serum uric acid levels and mortality in the japanese population: The yamagata (takahata) study. Clin Exp Nephrol. 2016;20:904-909
20. Kamei K, Konta T, Hirayama A, Ichikawa K, Kubota I, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T. Associations between serum uric acid levels and the incidence of nonfatal stroke: A nationwide community-based cohort study. Clin Exp Nephrol. 2016
21. Kadowaki S, Shishido T, Sasaki T, Sugai T, Narumi T, Honda Y, Otaki Y, Kinoshita D, Takahashi T, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Ishigami A, Takeishi Y, Kubota I. Deficiency of senescence marker protein 30 exacerbates cardiac injury after ischemia/reperfusion. Int J Mol Sci. 2016;17:542
22. Kadowaki S, Shishido T, Honda Y, Narumi T, Otaki Y, Kinoshita D, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Kubota I. Additive clinical value of serum brain-derived neurotrophic factor for prediction of chronic heart failure outcome. Heart Vessels. 2016;31:535-544
23. Iwayama T, Arimoto T, Ishigaki D, Hashimoto N, Kumagai YU, Koyama YO, Kiribayashi N, Netsu S, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Sato T, Watanabe T, Kubota I. The clinical value of nongated dual-source computed tomography in atrial fibrillation catheter ablation. J Cardiovasc Electrophysiol. 2016;27:34-40
24. Ishigaki D, Kutsuzawa D, Arimoto T, Iwayama T, Hashimoto N, Kumagai Y, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Nitobe J, Fukui A, Watanabe T, Kubota I. The association between defibrillation shock energy and acute cardiac damage in patients with implantable cardioverter defibrillators. J arrhythmia. 2016;32:481-485
25. Honda Y, Shishido T, Takahashi T, Watanabe T, Netsu S, Kinoshita D, Narumi T, Kadowaki S, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Kishida S, Kadomatsu K, Takeishi Y, Kubota I. Midkine deteriorates cardiac remodeling via epidermal growth factor receptor signaling in chronic kidney disease. Hypertension. 2016;67:857-865
26. Hashimoto N, Arimoto T, Narumi T, Iwayama T, Kutsuzawa D, Ishigaki D, Kumagai YU, Tamura H, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Watanabe T, Kubota I. The neutrophil-to-lymphocyte ratio predicts all-cause mortality in patients with implantable cardioverter defibrillators. Pacing and clinical electrophysiology : PACE. 2016
27. Hasegawa H, Watanabe T, Kato S, Toshima T, Yokoyama M, Aida Y, Nishiwaki M, Kadowaki S, Narumi T, Honda Y, Otaki Y, Honda S, Shunsuke N, Funayama A, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Abe S, Shibata Y, Kubota I. The role of macrophage transcription factor mafb in atherosclerotic plaque stability. Atherosclerosis. 2016;250:133-143
28. Daidoji H, Arimoto T, Iwayama T, Ishigaki D, Hashimoto N, Kumagai Y, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Watanabe T, Kubota I. Circulating heart-type fatty acid-binding protein levels predict ventricular fibrillation in brugada syndrome. J Cardiol. 2016;67:221-228
29. Ando K, Takahashi H, Watanabe T, Daidoji H, Otaki Y, Nishiyama S, Arimoto T, Shishido T, Miyashita T, Miyamoto T, Kubota I. Impact of serum uric acid levels on coronary plaque stability evaluated using integrated backscatter intravascular ultrasound in patients with coronary artery disease. J Atheroscler Thromb. 2016;23:932-939
30. Yashiro Y, Arimoto T, Hashimoto N, Tamura H, Iwayama T, Ishigaki D, Kumagai Y, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Watanabe T, Kubota I. Predictors of left atrial coagulation activity among paroxysmal atrial fibrillation patients. Circ J. 2015;79:61-69
31. Otaki Y, Takahashi H, Watanabe T, Yamaura G, Funayama A, Arimoto T, Shishido T, Miyamoto T, Kubota I. Heart-type fatty acid binding protein and high-sensitivity troponin t are myocardial damage markers that could predict adverse clinical outcomes in patients with peripheral artery disease. BBA Clinical. 2015;4:35-41
32. Otaki Y, Takahashi H, Watanabe T, Yamaura G, Funayama A, Arimoto T, Shishido T, Miyamoto T, Kubota I. Cystatin c-based egfr is a superior prognostic parameter to creatinine-based egfr in post-endovascular therapy peripheral artery disease patients. Circ J. 2015;79:2480-2486
33. Narumi T, Watanabe T, Kubota I. Simple measurement popularizes sarcopenia evaluation in patients with heart failure. Eur J Intern Med. 2015;26:e35
34. Narumi T, Watanabe T, Kadowaki S, Takahashi T, Yokoyama M, Kinoshita D, Honda Y, Funayama A, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. Sarcopenia evaluated by fat-free mass index is an important prognostic factor in patients with chronic heart failure. Eur J Intern Med. 2015;26:118-122
35. Narumi T, Shishido T, Otaki Y, Kadowaki S, Honda Y, Funayama A, Honda S, Hasegawa H, Kinoshita D, Yokoyama M, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Tanaka A, Woo CH, Abe J, Takeishi Y, Kubota I. High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis. J Mol Cell Cardiol. 2015;82:1-12
36. Llombart V, Antolin-Fontes A, Bustamante A, Giralt D, Rost NS, Furie K, Shibazaki K, Biteker M, Castillo J, Rodriguez-Yanez M, Fonseca AC, Watanabe T, Purroy F, Zhixin W, Etgen T, Hosomi N, Jafarian Kerman SR, Sharma JC, Knauer C, Santamarina E, Giannakoulas G, Garcia-Berrocoso T, Montaner J. B-type natriuretic peptides help in cardioembolic stroke diagnosis: Pooled data meta-analysis. Stroke. 2015;46:1187-1195
37. Ishino M, Shishido T, Suzuki S, Katoh S, Sasaki T, Funayama A, Netsu S, Hasegawa H, Honda S, Takahashi H, Arimoto T, Miyashita T, Miyamoto T, Watanabe T, Takeishi Y, Kubota I. Deficiency of long pentraxin ptx3 promoted neointimal hyperplasia after vascular injury. J Atheroscler Thromb. 2015;22:372-378
38. Ishigaki D, Arimoto T, Iwayama T, Hashimoto N, Kutsuzawa D, Kumagai Y, Nishiyama S, Takahashi H, Shishido T, Miyamoto T, Watanabe T, Kubota I. Prevention of immediate recurrence of atrial fibrillation with low-dose landiolol after radiofrequency catheter ablation. J Arrhythm. 2015;31:279-285
39. Hirayama A, Konta T, Hozawa A, Kawasaki R, Watanabe T, Shibata Y, Kayama T, Fukao A, Kubota I. Slight increase in urinary albumin excretion within the normal range predicts incident hypertension in a community-based japanese population: The takahata study. Hypertens Res. 2015;38:56-60
40. Funayama A, Watanabe T, Otaki Y, Nishiyama S, Arimoto T, Takahashi H, Shishido T, Miyamoto T, Kubota I. Utility of the japan arteriosclerosis longitudinal study score for identifying a high risk for vasospastic angina. Intern Med. 2015;54:881-885
41. Daidoji H, Takahashi H, Otaki Y, Tamura H, Arimoto T, Shishido T, Miyashita T, Miyamoto T, Watanabe T, Kubota I. A combination of plaque components analyzed by integrated backscatter intravascular ultrasound and serum pregnancy-associated plasma protein a levels predict the no-reflow phenomenon during percutaneous coronary intervention. Catheter Cardiovasc Interv. 2015;85:43-50
42. Watanabe T, Miyamoto T, Miyasita T, Shishido T, Arimoto T, Takahashi H, Nishiyama S, Hirono O, Matsui M, Sugawara S, Ikeno E, Miyawaki H, Akira F, Kubota I. Combination therapy of eicosapentaenoic acid and pitavastatin for coronary plaque regression evaluated by integrated backscatter intravascular ultrasonography (cherry study)-rationale and design. J Cardiol. 2014;64:236-239
43. Tamabuchi T, Watanabe T, Konta T, Tamura H, Nishiyama S, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Shibata Y, Ueno Y, Kato T, Fukao A, Kayama T, Kubota I. Impact of excess salt intake on plasma brain natriuretic peptide levels in a japanese general population with chronic kidney disease. Yamagata Med J. 2014;32:7-16
44. Sato K, Shibata Y, Abe S, Inoue S, Igarashi A, Yamauchi K, Aida Y, Nunomiya K, Nakano H, Sato M, Kimura T, Nemoto T, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Association between plasma adiponectin levels and decline in forced expiratory volume in 1 s in a general japanese population: The takahata study. Int J Med Sci. 2014;11:758-764
45. Sasaki T, Shishido T, Kadowaki S, Kitahara T, Suzuki S, Katoh S, Funayama A, Netsu S, Watanabe T, Goto K, Takeishi Y, Kubota I. Diacylglycerol kinase alpha exacerbates cardiac injury after ischemia/reperfusion. Heart Vessels. 2014;29:110-118
46. Sasaki S, Watanabe T, Tamura H, Nishiyama S, Wanezaki M, Sato C, Yamaura G, Ishino M, Arimoto T, Takahashi H, Shishido T, Miyamoto T, Kubota I. Left atrial strain as evaluated by two-dimensional speckle tracking predicts left atrial appendage dysfunction in patients with acute ischemic stroke. BBA Clinical. 2014;2:40-47
47. Otaki Y, Watanabe T, Takahashi H, Narumi T, Kadowaki S, Honda Y, Arimoto T, Shishido T, Miyamoto T, Konta T, Kubota I. Association of renal tubular damage with cardio-renal anemia syndrome in patients with heart failure. Int J Cardiol. 2014;173:222-228
48. Otaki Y, Watanabe T, Takahashi H, Kadowaki S, Narumi T, Honda Y, Wanezaki M, Sasaki S, Tamura H, Nishiyama S, Arimoto T, Shishido T, Miyamoto T, Kubota I. Association of plasma thioredoxin-1 with renal tubular damage and cardiac prognosis in patients with chronic heart failure. J Cardiol. 2014;64:353-359
49. Otaki Y, Watanabe T, Takahashi H, Hirayama A, Narumi T, Kadowaki S, Honda Y, Arimoto T, Shishido T, Miyamoto T, Konta T, Shibata Y, Fukao A, Daimon M, Ueno Y, Kato T, Kayama T, Kubota I. Association of heart-type fatty acid-binding protein with cardiovascular risk factors and all-cause mortality in the general population: The takahata study. PLoS One. 2014;9:e94834
50. Otaki Y, Takahashi H, Watanabe T, Kadowaki S, Narumi T, Honda Y, Hasegawa H, Honda S, Funayama A, Nishiyama S, Arimoto T, Shishido T, Miyashita T, Miyamoto T, Kubota I. Electrocardiographic left ventricular hypertrophy cornell product is a feasible predictor of cardiac prognosis in patients with chronic heart failure. Clin Res Cardiol. 2014;103:275-284
51. Otaki Y, Arimoto T, Takahashi H, Kadowaki S, Ishigaki D, Narumi T, Honda Y, Iwayama T, Nishiyama S, Shishido T, Miyashita T, Miyamoto T, Watanabe T, Kubota I. Prognostic value of myocardial damage markers in patients with chronic heart failure with atrial fibrillation. Intern Med. 2014;53:661-668
52. Netsu S, Shishido T, Kitahara T, Honda Y, Funayama A, Narumi T, Kadowaki S, Takahashi H, Miyamoto T, Arimoto T, Nishiyama S, Watanabe T, Woo CH, Takeishi Y, Kubota I. Midkine exacerbates pressure overload-induced cardiac remodeling. Biochem Biophys Res Commun. 2014;443:205-210
53. Netsu S, Honda Y, Watanabe T, Shibata Y, Nishiyama S, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Konta T, Ueno Y, Kato T, Fukao A, Kayama T, Kubota I. Comorbidity of airflow limitation in patients with cardiovascular disease. Exp Clin Cardiol. 2014;20:3788-3800
54. Narumi T, Watanabe T, Kadowaki S, Otaki Y, Honda Y, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. The obesity paradox is not observed in chronic heart failure patients with metabolic syndrome. EXCLI J. 2014;13:516-525
55. Narumi T, Watanabe T, Kadowaki S, Kinoshita D, Yokoyama M, Honda Y, Otaki Y, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. Impact of serum omentin-1 levels on cardiac prognosis in patients with heart failure. Cardiovasc Diabetol. 2014;13:84
56. Narumi T, Watanabe T, Iwayama T, Kadowaki S, Otaki Y, Honda Y, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyamoto T, Kubota I. Increased epicardial adipose tissue volume predicts insulin resistance and coronary artery disease in non-obese subjects without metabolic syndrome. IJC Metabolic & Endocrine. 2014;3:14-19
57. Katoh S, Honda S, Watanabe T, Suzuki S, Ishino M, Kitahara T, Funayama A, Netsu S, Sasaki T, Shishido T, Miyamoto T, Sadahiro M, Kubota I. Atrial endothelial impairment through toll-like receptor 4 signaling causes atrial thrombogenesis. Heart Vessels. 2014;29:263-272
58. Iwayama T, Nitobe J, Watanabe T, Ishino M, Tamura H, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyashita T, Miyamoto T, Toyama S, Sadahiro M, Kubota I. Role of epicardial adipose tissue in coronary artery disease in non-obese patients. J Cardiol. 2014;63:344-349
59. Iwayama T, Arimoto T, Tamura H, Wanezaki M, Sasaki S, Nishiyama S, Kutsuzawa D, Ishigaki D, Nitobe J, Suzuki H, Watanabe T, Kubota I. Two-dimensional speckle tracking imaging as a novel strategy for accurately identifying the accessory pathway. Intern Med. 2014;53:1527-1530
60. Honda S, Miyamoto T, Watanabe T, Narumi T, Kadowaki S, Honda Y, Otaki Y, Hasegawa H, Netsu S, Funayama A, Ishino M, Nishiyama S, Takahashi H, Arimoto T, Shishido T, Miyashita T, Kubota I. A novel mouse model of aortic valve stenosis induced by direct wire injury. Arterioscler Thromb Vasc Biol. 2014;34:270-278
61. Suzuki S, Shishido T, Funayama A, Netsu S, Ishino M, Kitahara T, Sasaki T, Katoh S, Otaki Y, Watanabe T, Shibata Y, Mantovani A, Takeishi Y, Kubota I. Long pentraxin ptx3 exacerbates pressure overload-induced left ventricular dysfunction. PLoS One. 2013;8:e53133
62. Shibata Y, Inoue S, Igarashi A, Yamauchi K, Abe S, Aida Y, Nunomiya K, Sato M, Nakano H, Sato K, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Elevated serum iron is a potent biomarker for spirometric resistance to cigarette smoke among japanese males: The takahata study. PLoS One. 2013;8:e74020
63. Shibata Y, Inoue S, Igarashi A, Yamauchi K, Abe S, Aida Y, Nunomiya K, Sato M, Nakano H, Sato K, Nemoto T, Kimura T, Watanabe T, Konta T, Daimon M, Ueno Y, Kato T, Kayama T, Kubota I. A lower level of forced expiratory volume in 1 second is a risk factor for all-cause and cardiovascular mortality in a japanese population: The takahata study. PLoS One. 2013;8:e83725
64. Shibata Y, Abe S, Inoue S, Igarashi A, Yamauchi K, Aida Y, Kishi H, Nunomiya K, Nakano H, Sato M, Sato K, Kimura T, Nemoto T, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Relationship between plasma fibrinogen levels and pulmonary function in the japanese population: The takahata study. Int J Med Sci. 2013;10:1530-1536
65. Sato M, Shibata Y, Abe S, Inoue S, Igarashi A, Yamauchi K, Aida Y, Kishi H, Nunomiya K, Nakano H, Sato K, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Retrospective analysis of the relationship between decline in fev(1) and abdominal circumference in male smokers: The takahata study. Int J Med Sci. 2013;10:1-7
66. Otaki Y, Watanabe T, Takahashi H, Hasegawa H, Honda S, Funayama A, Netsu S, Ishino M, Arimoto T, Shishido T, Miyashita T, Miyamoto T, Konta T, Kubota I. Acidic urine is associated with poor prognosis in patients with chronic heart failure. Heart Vessels. 2013;28:735-741
67. Otaki Y, Watanabe T, Shishido T, Takahashi H, Funayama A, Narumi T, Kadowaki S, Hasegawa H, Honda S, Netsu S, Ishino M, Arimoto T, Miyashita T, Miyamoto T, Konta T, Kubota I. The impact of renal tubular damage, as assessed by urinary beta2-microglobulin-creatinine ratio, on cardiac prognosis in patients with chronic heart failure. Circ Heart Fail. 2013;6:662-668
68. Nunomiya K, Shibata Y, Abe S, Inoue S, Igarashi A, Yamauchi K, Aida Y, Kishi H, Sato M, Watanabe T, Konta T, Ueno Y, Kato T, Yamashita H, Kayama T, Kubota I. Hyperhomocysteinaemia predicts the decline in pulmonary function in healthy male smokers. Eur Respir J. 2013;42:18-27
69. Niizeki T, Takeishi Y, Sasaki T, Kaneko K, Sugawara S, Watanabe T, Kubota I. Usefulness of albuminuria as a prognostic indicator in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol. 2013;111:1180-1186
70. Narumi T, Arimoto T, Funayama A, Kadowaki S, Otaki Y, Nishiyama S, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Watanabe T, Kubota I. Prognostic importance of objective nutritional indexes in patients with chronic heart failure. J Cardiol. 2013;62:307-313
71. Nakano H, Shibata Y, Inoue S, Igarashi A, Yamauchi K, Abe S, Sato M, Aida Y, Nunomiya K, Kimura T, Nemoto T, Watanabe T, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Relationships between values of antibodies to several connective tissue disease autoantigens and pulmonary function in a japanese general population: The takahata study. PLoS One. 2013;8:e81678
72. Mashima Y, Konta T, Ichikawa K, Ikeda A, Suzuki K, Wanezaki M, Nishiyama S, Watanabe T, Kubota I. Rapid decline in renal function after acute myocardial infarction. Clin Nephrol. 2013;79:15-20
73. Konta T, Kudo K, Sato H, Ichikawa K, Ikeda A, Suzuki K, Hirayama A, Shibata Y, Watanabe T, Daimon M, Kato T, Ueno Y, Kayama T, Kubota I. Albuminuria is an independent predictor of all-cause and cardiovascular mortality in the japanese population: The takahata study. Clin Exp Nephrol. 2013;17:805-810
74. Funayama A, Shishido T, Netsu S, Narumi T, Kadowaki S, Takahashi H, Miyamoto T, Watanabe T, Woo CH, Abe J, Kuwahara K, Nakao K, Takeishi Y, Kubota I. Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure. Cardiovasc Res. 2013;99:657-664
75. Funayama A, Shishido T, Miyashita T, Netsu S, Otaki Y, Arimoto T, Takahashi H, Miyamoto T, Watanabe T, Konta T, Kubota I. Renal tubulointerstitial damage is associated with short-term cardiovascular events in patients with myocardial infarction. Circ J. 2013;77:484-489
76. Tamura H, Watanabe T, Nishiyama S, Sasaki S, Wanezaki M, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Kubota I. Prognostic value of low left atrial appendage wall velocity in patients with ischemic stroke and atrial fibrillation. J Am Soc Echocardiogr. 2012;25:576-583
77. Tamura H, Watanabe T, Nishiyama S, Sasaki S, Wanezaki M, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Hirono O, Kayama T, Kubota I. Elevated plasma brain natriuretic peptide levels predict left atrial appendage dysfunction in patients with acute ischemic stroke. J Cardiol. 2012;60:126-132
78. Narumi T, Shishido T, Kiribayashi N, Kadowaki S, Nishiyama S, Takahashi H, Arimoto T, Miyashita T, Miyamoto T, Watanabe T, Shibata Y, Konta T, Ueno Y, Kato T, Kayama T, Kubota I. Impact of insulin resistance on silent and ongoing myocardial damage in normal subjects: The takahata study. Exp Diabetes Res. 2012;2012:815098
79. Kutsuzawa D, Arimoto T, Watanabe T, Shishido T, Miyamoto T, Miyashita T, Takahashi H, Niizeki T, Takeishi Y, Kubota I. Ongoing myocardial damage in patients with heart failure and preserved ejection fraction. J Cardiol. 2012;60:454-461
80. Kutsuzawa D, Arimoto T, Shishido T, Sasaki S, Iwayama T, Ishigaki D, Takahashi H, Miyashita T, Miyamoto T, Nitobe J, Watanabe T, Kubota I. Device troubleshooting: Cross connection of ventricular leads in a patient with decreased right ventricular electrical activity. Europace. 2012;14:1217-1219
81. Daidoji H, Arimoto T, Nitobe J, Tamura H, Kutsuzawa D, Ishigaki D, Ishino M, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Watanabe T, Kubota I. Circulating heart-type fatty acid binding protein levels predict the occurrence of appropriate shocks and cardiac death in patients with implantable cardioverter-defibrillators. J Card Fail. 2012;18:556-563
82. Watanabe T, Kubota I. [idiopathic cardiomyopathy]. Nihon Naika Gakkai Zasshi. 2011;100:646-650
83. Tamura H, Watanabe T, Nishiyama S, Sasaki S, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Nitobe J, Hirono O, Kubota I. Increased left atrial volume index predicts a poor prognosis in patients with heart failure. J Card Fail. 2011;17:210-216
84. Suzuki S, Shishido T, Ishino M, Katoh S, Sasaki T, Nishiyama S, Miyashita T, Miyamoto T, Nitobe J, Watanabe T, Takeishi Y, Kubota I. 8-hydroxy-2'-deoxyguanosine is a prognostic mediator for cardiac event. Eur J Clin Invest. 2011;41:759-766
85. Shishido T, Konta T, Nishiyama S, Miyashita T, Miyamoto T, Takasaki S, Nitobe J, Watanabe T, Takeishi Y, Kubota I. Suppressive effects of valsartan on microalbuminuria and crp in patients with metabolic syndrome (val-mets). Clin Exp Hypertens. 2011;33:117-123
86. Shibata Y, Watanabe T, Osaka D, Abe S, Inoue S, Tokairin Y, Igarashi A, Yamauchi K, Kimura T, Kishi H, Aida Y, Nunomiya K, Nemoto T, Sato M, Konta T, Kawata S, Kato T, Kayama T, Kubota I. Impairment of pulmonary function is an independent risk factor for atrial fibrillation: The takahata study. Int J Med Sci. 2011;8:514-522
87. Nemoto T, Shibata Y, Osaka D, Abe S, Inoue S, Tokairin Y, Igarashi A, Yamauchi K, Kimura T, Kishi H, Nishiwaki M, Aida Y, Nunomiya K, Sato M, Watanabe T, Konta T, Kawata S, Kato T, Kayama T, Kubota I. Impact of cigarette smoking on maximal expiratory flows in a general population: The takahata study. Intern Med. 2011;50:2547-2555
88. Mashima Y, Konta T, Kudo K, Takasaki S, Ichikawa K, Suzuki K, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I. Increases in urinary albumin and beta2-microglobulin are independently associated with blood pressure in the japanese general population: The takahata study. Hypertens Res. 2011;34:831-835
89. Mashima Y, Konta T, Kudo K, Suzuki K, Ikeda A, Ichikawa K, Shibata Y, Watanabe T, Tamiya G, Kato T, Kawata S, Kubota I. Polymorphism of proinflammatory cytokine genes and albuminuria in the japanese general population: The takahata study. Nephrol Dial Transplant. 2011;26:3902-3907
90. Kutsuzawa D, Arimoto T, Watanabe T, Nitobe J, Miyamoto T, Miyashita T, Shishido T, Takahashi H, Nishiyama S, Kubota I. Persistent abnormal value of late potential in brugada syndrome associated with hypokalemia. Ann Noninvasive Electrocardiol. 2011;16:104-106
91. Kudo K, Konta T, Mashima Y, Ichikawa K, Takasaki S, Ikeda A, Hoshikawa M, Suzuki K, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I. The association between renal tubular damage and rapid renal deterioration in the japanese population: The takahata study. Clin Exp Nephrol. 2011;15:235-241
92. Kishi H, Shibata Y, Osaka D, Abe S, Inoue S, Tokairin Y, Igarashi A, Yamauchi K, Kimura T, Sato M, Aida Y, Watanabe T, Konta T, Kawata S, Kato T, Kubota I. Fev6 and fev1/fev6 in japanese participants of the community-based annual health check: The takahata study. Intern Med. 2011;50:87-93
93. Funayama A, Watanabe T, Tamabuchi T, Otaki Y, Netsu S, Hasegawa H, Honda S, Ishino M, Arimoto T, Takahashi H, Shishido T, Miyamoto T, Nitobe J, Kubota I. Elevated cystatin c levels predict the incidence of vasospastic angina. Circ J. 2011;75:2439-2444
94. Funayama A, Shishido T, Netsu S, Ishino M, Sasaki T, Katoh S, Takahashi H, Arimoto T, Miyamoto T, Nitobe J, Watanabe T, Kubota I. Serum pregnancy-associated plasma protein a in patients with heart failure. J Card Fail. 2011;17:819-826
95. Arimoto T, Watanabe T, Nitobe J, Iwayama T, Kutsuzawa D, Miyamoto T, Miyashita T, Shishido T, Takahashi H, Nozaki N, Fukui A, Kubota I. Difference of clinical course after catheter ablation of atrioventricular nodal reentrant tachycardia between younger and older patients: Atrial vulnerability predicts new onset of atrial fibrillation. Intern Med. 2011;50:1649-1655
96. Aida Y, Shibata Y, Osaka D, Abe S, Inoue S, Fukuzaki K, Tokairin Y, Igarashi A, Yamauchi K, Nemoto T, Nunomiya K, Kishi H, Sato M, Watanabe T, Konta T, Kawata S, Kato T, Kubota I. The relationship between serum uric acid and spirometric values in participants in a health check: The takahata study. Int J Med Sci. 2011;8:470-478
97. Tamura H, Watanabe T, Hirono O, Nishiyama S, Sasaki S, Shishido T, Miyashita T, Miyamoto T, Nitobe J, Kayama T, Kubota I. Low wall velocity of left atrial appendage measured by trans-thoracic echocardiography predicts thrombus formation caused by atrial appendage dysfunction. J Am Soc Echocardiogr. 2010;23:545-552 e541
98. Sasaki T, Takeishi Y, Suzuki S, Niizeki T, Kitahara T, Katoh S, Ishino M, Shishido T, Watanabe T, Kubota I. High serum level of neopterin is a risk factor of patients with heart failure. Int J Cardiol. 2010;145:318
99. Osaka D, Shibata Y, Abe S, Inoue S, Tokairin Y, Igarashi A, Yamauchi K, Kimura T, Sato M, Kishi H, Takabatake N, Sata M, Watanabe T, Konta T, Kawata S, Kato T, Kubota I. Relationship between habit of cigarette smoking and airflow limitation in healthy japanese individuals: The takahata study. Intern Med. 2010;49:1489-1499
100. Nishiyama S, Watanabe T, Arimoto T, Takahashi H, Shishido T, Miyashita T, Miyamoto T, Nitobe J, Shibata Y, Konta T, Kawata S, Kato T, Fukao A, Kubota I. Trends in coronary risk factors among patients with acute myocardial infarction over the last decade: The yamagata ami registry. J Atheroscler Thromb. 2010;17:989-998
101. Konta T, Takasaki S, Ichikawa K, Emi M, Toriyama S, Satoh H, Ikeda A, Suzuki K, Mashima Y, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I. The novel and independent association between single-point snp of nphp4 gene and renal function in non-diabetic japanese population: The takahata study. J Hum Genet. 2010;55:791-795
102. Kitahara T, Shishido T, Suzuki S, Katoh S, Sasaki T, Ishino M, Nitobe J, Miyamoto T, Miyashita T, Watanabe T, Takeishi Y, Kubota I. Serum midkine as a predictor of cardiac events in patients with chronic heart failure. J Card Fail. 2010;16:308-313
103. Katoh S, Shishido T, Kutsuzawa D, Arimoto T, Netsu S, Funayama A, Ishino M, Niizeki T, Nishiyama S, Takahashi H, Miyashita T, Miyamoto T, Nitobe J, Watanabe T, Kubota I. Iodine-123-metaiodobenzylguanidine imaging can predict future cardiac events in heart failure patients with preserved ejection fraction. Ann Nucl Med. 2010;24:679-686
104. Hasegawa H, Arimoto T, Iwayama T, Kutsuzawa D, Nishiyama S, Nitobe J, Watanabe T, Sadahiro M, Kubota I. Images in cardiovascular medicine. Silent myocardial ischemia in adult bland-white-garland syndrome. Circ J. 2010;74:2239-2240
105. Arimoto T, Watanabe T, Nitobe J, Kubota I. Catheter ablation of ventricular tachycardia induced by injection of acetylcholine in the right coronary artery. J Cardiovasc Electrophysiol. 2010;21:1410-1412
106. Suzuki K, Konta T, Takasaki S, Ikeda A, Ichikawa K, Sato H, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I. High variability of albuminuria in nondiabetic population: The takahata study. Clin Exp Nephrol. 2009;13:452-459
107. Niizeki T, Takeishi Y, Watanabe T, Nitobe J, Miyashita T, Miyamoto T, Kitahara T, Suzuki S, Sasaki T, Bilim O, Ishino M, Kubota I. Relation of serum heat shock protein 60 level to severity and prognosis in chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol. 2008;102:606-610
108. Niizeki T, Takeishi Y, Arimoto T, Nozaki N, Hirono O, Watanabe T, Nitobe J, Miyashita T, Miyamoto T, Koyama Y, Kitahara T, Suzuki S, Sasaki T, Kubota I. Persistently increased serum concentration of heart-type fatty acid-binding protein predicts adverse clinical outcomes in patients with chronic heart failure. Circ J. 2008;72:109-114
109. Ishino M, Takeishi Y, Niizeki T, Watanabe T, Nitobe J, Miyamoto T, Miyashita T, Kitahara T, Suzuki S, Sasaki T, Bilim O, Kubota I. Risk stratification of chronic heart failure patients by multiple biomarkers: Implications of bnp, h-fabp, and ptx3. Circ J. 2008;72:1800-1805
110. Takeishi Y, Niizeki T, Arimoto T, Nozaki N, Hirono O, Nitobe J, Watanabe T, Takabatake N, Kubota I. Serum resistin is associated with high risk in patients with congestive heart failure--a novel link between metabolic signals and heart failure. Circ J. 2007;71:460-464
111. Niizeki T, Takeishi Y, Arimoto T, Takabatake N, Nozaki N, Hirono O, Watanabe T, Nitobe J, Harada M, Suzuki S, Koyama Y, Kitahara T, Sasaki T, Kubota I. Heart-type fatty acid-binding protein is more sensitive than troponin t to detect the ongoing myocardial damage in chronic heart failure patients. J Card Fail. 2007;13:120-127
112. Koyama Y, Takeishi Y, Arimoto T, Niizeki T, Shishido T, Takahashi H, Nozaki N, Hirono O, Tsunoda Y, Nitobe J, Watanabe T, Kubota I. High serum level of pentosidine, an advanced glycation end product (age), is a risk factor of patients with heart failure. J Card Fail. 2007;13:199-206
113. Kitahara T, Takeishi Y, Arimoto T, Niizeki T, Koyama Y, Sasaki T, Suzuki S, Nozaki N, Hirono O, Nitobe J, Watanabe T, Kubota I. Serum carboxy-terminal telopeptide of type i collagen (ictp) predicts cardiac events in chronic heart failure patients with preserved left ventricular systolic function. Circ J. 2007;71:929-935
114. Arimoto T, Takeishi Y, Niizeki T, Nozaki N, Hirono O, Watanabe T, Nitobe J, Tsunoda Y, Suzuki S, Koyama Y, Kitahara T, Okada A, Takahashi K, Kubota I. Cardiac sympathetic denervation and ongoing myocardial damage for prognosis in early stages of heart failure. J Card Fail. 2007;13:34-41
115. Niizeki T, Takeishi Y, Arimoto T, Okuyama H, Nozaki N, Hirono O, Tsunoda Y, Watanabe T, Nitobe J, Miyashita T, Takahashi H, Koyama Y, Kubota I. Hyperuricemia associated with high cardiac event rates in the elderly with chronic heart failure. J Cardiol. 2006;47:219-228
116. Watanabe T, Takeishi Y, Hirono O, Itoh M, Matsui M, Nakamura K, Tamada Y, Kubota I. C-reactive protein elevation predicts the occurrence of atrial structural remodeling in patients with paroxysmal atrial fibrillation. Heart Vessels. 2005;20:45-49
117. Watanabe T, Suzuki J, Yamawaki H, Sharma VK, Sheu SS, Berk BC. Losartan metabolite exp3179 activates akt and endothelial nitric oxide synthase via vascular endothelial growth factor receptor-2 in endothelial cells: Angiotensin ii type 1 receptor-independent effects of exp3179. Circulation. 2005;112:1798-1805
118. Watanabe T, Barker TA, Berk BC. Angiotensin ii and the endothelium: Diverse signals and effects. Hypertension. 2005;45:163-169
119. Yamauchi S, Takeishi Y, Minamihaba O, Arimoto T, Hirono O, Takahashi H, Miyamoto T, Nitobe J, Nozaki N, Tachibana H, Watanabe T, Fukui A, Kubota I. Angiotensin-converting enzyme inhibition improves cardiac fatty acid metabolism in patients with congestive heart failure. Nucl Med Commun. 2003;24:901-906
120. Yamauchi S, Yamaki M, Watanabe T, Yuuki K, Kubota I, Tomoike H. Restitution properties and occurrence of ventricular arrhythmia in lqt2 type of long qt syndrome. J Cardiovasc Electrophysiol. 2002;13:910-914
121. Watanabe T, Yamaki M, Yamauchi S, Minamihaba O, Miyashita T, Kubota I, Tomoike H. Regional prolongation of ari and altered restitution properties cause ventricular arrhythmia in heart failure. Am J Physiol Heart Circ Physiol. 2002;282:H212-218
122. Watanabe T, Yamaki M, Tachibana H, Yamauchi S, Kubota I, Tomoike H. Anisotropic effects of sodium channel blockers on the wavelength for ventricular excitation in dogs. Jpn Circ J. 2000;64:689-694
123. Miyashita T, Kubota I, Yamaki M, Watanabe T, Yamauchi S, Tomoike H. 4-aminopyridine inhibits the occurrence of ventricular fibrillation but not ventricular tachycardia in the reperfused, isolated rat heart. Jpn Circ J. 2000;64:602-605
124. Watanabe T, Yamaki M, Kubota I, Tachibana H, Tomoike H. Relation between activation sequence fluctuation and arrhythmogenicity in sodium-channel blockades. Am J Physiol. 1999;277:H971-977
125. Watanabe T, Kubota I, Yamaki M, Tachibana H, Tomoike H. Direct effects of class i antiarrhythmic drugs on epicardial electrograms in dogs. Jpn Heart J. 1999;40:621-628
126. Tachibana H, Yamaki M, Kubota I, Watanabe T, Yamauchi S, Tomoike H. Intracoronary flecainide induces st alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current. Circulation. 1999;99:1637-1643
127. Tachibana H, Kubota I, Yamaki M, Watanabe T, Tomoike H. Canine model of ventricular fibrillation using programmed stimuli and localized myocardial warming or cooling. Jpn Heart J. 1999;40:179-188
128. Watanabe T, Yamaki M, Tachibana H, Kubota I, Tomoike H. Decrease in the high frequency qrs components depending on the local conduction delay. Jpn Circ J. 1998;62:844-848
129. Tachibana H, Kubota I, Yamaki M, Watanabe T, Tomoike H. Discordant s-t alternans contributes to formation of reentry: A possible mechanism of reperfusion arrhythmia. Am J Physiol. 1998;275:H116-121

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4. 西山悟史,渡邉哲:左房,右房の評価.心エコー 2016; 17(1):34-43.
5. 有本貴範,渡邉哲:心電図でのBrugada症候群の読み方は?【rsr'型との鑑別法】回答.日本医事新報 2016; 4798:61-62.
6. 西山悟史,渡邉哲:感染性心内膜炎.心エコー 2015; 16(1): 68-77.
7. 渡邉哲:Brugada型心電図に出会ったら.平成26年度山形県医師会学術雑誌 2015;48:149-153.
8. 渡邉哲,久保田功:特集 今後期待される新規バイオマーカー 4.心血管疾患の炎症性バイオマーカー.日本抗加齢医学会雑誌 ANTI-AGING MEDICINE 2014;10(1): 35-39.
9. 渡邉哲,久保田功:海外文献紹介 循環器内科領域 冠動脈インターベンション後の抗血小板薬2剤併用療法中止と心イベントの関係:Cessation of dual antiplatelet treatment and cardiac vents after percutaneous coronary intervention (PARIS); 2 year results from a prospective observational study. Angiology Frontier 2014;13(1):80-81. メディカルレビュー社(東京)
10. 渡邉哲,久保田功:海外文献紹介 循環器内科領域 治療抵抗性高血圧に対する腎除神経術の対照試験:A controlled trial of renal denervation for resistant hypertension. Angiology Frontier 2014;13(2): 80-81. メディカルレビュー社(東京)
11. 渡邉哲,久保田功:海外文献紹介 循環器内科領域 無症候性頸動脈狭窄に対するスクリーニング検査はむしろ有害か?:Screening for asymptomatic carotid artery stenosis; U.S.preventive services task force recommendation statement. Angiology Frontier 2014;13(3):78-79. メディカルレビュー社(東京)
12. 渡邉哲,久保田功:特集 心腎貧血連関 序文.渡邉哲,久保田功企画編集.循環器内科 2013;74(5): 431-432. 科学評論社(東京)
13. 大瀧陽一郎,渡邉哲:特集 心腎貧血連関 慢性腎臓病と心不全.渡邉哲,久保田功企画編集.循環器内科 2013;74(5):473-478. 科学評論社(東京)
14. 渡邉哲:レベル別 心電図読解マスタードリル50.Q12・19・38・45. HEART nursing 2012;25(8): 10,12,21,25,35,39-40,54-55,60.
15. 渡邉哲,久保田功:第37回内科学の展望 難治性内科疾患の克服に向けて 4.特発性心筋症.日本内科学会雑誌 2011; 100 (3): 646-650.
16. 小山容,竹石恭知,有本貴範,新関武史,宍戸哲郎,高橋大,野崎直樹,廣野摂,角田裕一,二藤部丈司,渡邉哲,久保田功:終末糖化産物の一つであるペントシジンは心不全の危険因子である.心臓 2007; 39(1): 22-31.

【受賞】
平成12年 第5回 日本心臓財団・ファイザー心血管病研究助成 優秀賞
平成12年度 福田記念医療技術振興財団 研究助成
平成15年 第16回 日本心臓財団・バイエル薬品 海外留学助成金
平成20年度 福田記念医療技術振興財団 研究助成
平成28年 第15回山形大学医学会学術賞 特別賞(金賞)

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