𠮷田 誠 よしだ まこと 先生

来歴等

略歴

1989年 九州大学付属病院 研修医（呼吸器科・循環器内科）
1990年 九州厚生年金病院 内科研修医
1991年 新日本製鐵八幡製鐵所病院呼吸器科
1992年 九州大学大学院医学系研究科内科系専攻博士課程 入学
1996年 九州大学大学院医学系研究科内科系専攻博士課程 卒業・学位取得
1996年 国立療養所田川新生病院呼吸器科
1996年 九州大学医学部呼吸器科
2000年 カナダ マクマスター大学 呼吸器研究部門
2002年 国立療養所南福岡病院 内科医師
2004年 九州大学医学部呼吸器科
2006年 独立行政法人 国立病院機構 福岡東医療センター 内科医長
2008年 独立行政法人 国立病院機構 福岡病院 臨床検査科長
2013年 独立行政法人 国立病院機構 福岡病院 統括診療部長
2019年 独立行政法人 国立病院機構 福岡病院 院長

論文

• Imidafenacin, An Orally Active Muscarinic Receptor Antagonist, Improves Pulmonary Function In Patients With Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled 3×3 Crossover Phase II Trial.International Journal of Chronic Obstructive Pulmonary Disease, September 2019, DOI: 10.2147/copd.s223002

  Kentaro Machida, Tomotaka Kawayama, Masaharu Kinoshita, Masakazu Ichinose, Tohru Tsuda, Shohei Takata, Hiroshi Koto, Makoto Yoshida, Yoshinori Ashihara, Masaru Kawashima, Hideaki Suna, Hiromasa Inoue

• Simple standard equation for daily step count in Japanese patients with chronic obstructive pulmonary disease.International Journal of Chronic Obstructive Pulmonary Disease, August 2019 DOI: 10.2147/copd.s218705

  Masanori Nakanishi, Yoshiaki Minakata, Rie Tanaka, Hisatoshi Sugiura, Hikaru Kuroda, Makoto Yoshida, Nobuyuki Yamamoto

• Adherence barriers to inhaled medicines in Japanese older patients with asthma evaluated using the "Adherence Starts with Knowledge 20" (ASK-20) questionnaire. J Asthma. 2018 Sep 19:1-10. doi: 10.1080/02770903.2018.1484132. [Epub ahead of print]

  Sasaki J, Kawayama T, Yoshida M, Takahashi K, Fujii K, Machida K, Kinoshita T, Hoshino T; and the Kyushu Asthma Seminar Investigators.

• Differences in Adherence Barriers to Inhaled Medicines between Japanese Patients with Chronic Obstructive Pulmonary Disease and Asthma Evaluated using the "Adherence Starts with Knowledge 20" (ASK-20) Questionnaire.Intern Med. 2019 Jan 15;58(2):175-185.

  Toyama T, Kawayama T, Kinoshita T, Imamura Y, Yoshida M, Takahashi K, Fujii K, Higashimoto I, Hoshino T.

• Disseminated Cryptococcosis with Marked Eosinophilia in a Postpartum Woman.Intern Med. 2018 Jan 1;57(1):135-139.

  Yokoyama T, Kadowaki M, Yoshida M, Suzuki K, Komori M, Iwanaga T.

• Identification of patterns of factors preceding severe or life-threatening asthma exacerbations in a nationwide study. Allergy. 2018 May;73(5):1110-1118. doi: 10.1111/all.13374. Epub 2017 Dec 19

  Tanaka H, Nakatani E, Fukutomi Y, Sekiya K, Kaneda H, Iikura M, Yoshida M, Takahashi K, Tomii K, Nishikawa M, Kaneko N, Sugino Y, Shinkai M, Ueda T, Tanikawa Y, Shirai T, Hirabayashi M, Aoki T, Kato T, Iizuka K, Fujii M, Taniguchi M.

• Poor pharmacological adherence to inhaled medicines compared with oral medicines in Japanese patients with asthma and chronic obstructive pulmonary disease. Allergol Int. 2017 Jul;66(3):482-484.

  Imamura Y, Kawayama T, Kinoshita T, Sakazaki Y, Yoshida M, Takahashi K, Fujii K, Ando M, Hoshino T, Iwanaga T, Kohrogi H; Kyushu Asthma Seminar Investigators.

• Effects of tiotropium on lung function in current smokers and never smokers with bronchial asthma.Pulm Pharmacol Ther. 2017 Feb;42:7-12. doi: 10.1016/j.pupt.2016.11.004.

  Yoshida M, Kaneko Y, Ishimatsu A, Komori M, Iwanaga T, Inoue H.

• Severe or life-threatening asthma exacerbation: patient heterogeneity identified by cluster analysis. Clin Exp Allergy. 2016 Aug;46(8):1043-55. doi: 10.1111/cea.12738.

  Sekiya K, Nakatani E, Fukutomi Y, Kaneda H, Iikura M, Yoshida M, Takahashi KI, Tomii K, Nishikawa M, Kaneko N, Sugino Y, Shinkai M, Ueda T, Tanikawa Y, Shirai T, Hirabayashi M, Aoki T, Kato T, Iizuka K, Homma S, Taniguchi M, Tanaka H.

• Breath Sound Intensity during Tidal Breathing in COPD Patients.Intern Med. 2015;54(10):1183-91. doi: 10.2169/internalmedicine.54.3161. Epub 2015 May 15.

  Ishimatsu A, Nakano H, Nogami H, Yoshida M, Iwanaga T, Hoshino T.

• Ghrelin Administration for Chronic Respiratory Failure: A Randomized Dose-Comparison Trial.Lung. 2015 Apr;193(2):239-47.Lung. 2015 Jan 30. [Epub ahead of print]

  Matsumoto N, Miki K, Tsubouchi H, Sakamoto A, Arimura Y, Yanagi S, Iiboshi H, Yoshida M, Souma R, Ishimoto H, Yamamoto Y, Yatera K, Yoshikawa M, Sagara H, Iwanaga T, Mukae H, Maekura R, Kimura H, Nakazato M, Kangawa K.

• Prevalence of asthma with airflow limitation, COPD, and COPD with variable airflow limitation in older subjects in a general Japanese population: the Hisayama Study. Respir Investig. 2015 Jan;53(1):22-9. doi: 10.1016/j.resinv.2014.08.002. Epub 2014 Oct 1.

  Matsumoto K, Seki N, Fukuyama S, Moriwaki A, Kan-o K, Matsunaga Y, Noda N, Yoshida M, Koto H, Takata S, Nakanishi Y, Kiyohara Y, Inoue H; Hisayama Pulmonary Physiology Study Group.

• Interleukin-18 expression, CD8(+) T cells, and eosinophils in lungs of nonsmokers with fatal asthma.Ann Allergy Asthma Immunol. 2014 Jan;112(1):23-28.e1. doi: 10.1016/j.anai.2013.09.004. Epub 2013 Oct 2.

  Oda H, Kawayama T, Imaoka H, Sakazaki Y, Kaku Y, Okamoto M, Kitasato Y, Edakuni N, Takenaka S, Yoshida M, Iwanaga T, Kato S, O'Byrne PM, Hoshino T.

• Low-dose salbutamol suppresses airway responsiveness to histamine but not methacholine in subjects with asthma.Respir Investig. 2013 Sep;51(3):158-65. doi: 10.1016/j.resinv.2013.03.001. Epub 2013 May 7.

  Matsumoto K, Aizawa H, Fukuyama S, Yoshida M, Komori M, Takata S, Koto H, Inoue H.

• Effects of tiotropium on lung function in severe asthmatics with or without emphysematous changes.Pulm Pharmacol Ther. 2013 Apr;26(2):159-66. doi: 10.1016/j.pupt.2012.09.007. Epub 2012 Oct 13.

  Yoshida M, Nakano T, Fukuyama S, Matsumoto T, Eguchi M, Moriwaki A, Takata S, Machida K, Kanaya A, Matsumoto K, Nakanishi Y, Inoue H.

• Comparison of Aspergillus galactomannan antigen testing with a new cut-off index and Aspergillus precipitating antibody testing for the diagnosis of chronic pulmonary aspergillosis.Respirology. 2009 Jul;14(5):701-8. doi: 10.1111/j.1440-1843.2009.01548.x.

  Kitasato Y, Tao Y, Hoshino T, Tachibana K, Inoshima N, Yoshida M, Takata S, Okabayashi K, Kawasaki M, Iwanaga T, Aizawa H.

• Effects of salmeterol in patients with persistent asthma receiving inhaled corticosteroid plus theophylline.Respiration. 2007;74(6):611-6. Epub 2006 Sep 5.

  Inoue H, Komori M, Matsumoto T, Fukuyama S, Matsumura M, Nakano T, Tsuda M, Matsumoto K, Kanaya A, Moriwaki A, Aizawa H, Yoshida M, Nakanishi Y.

• Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge.Clin Exp Allergy. 2006 Nov;36(11):1417-24.

  Kawayama T, O'Byrne PM, Watson RM, Killian KJ, Duong M, Yoshida M, Gauvreau GM.

• Different profiles of T-cell IFN-gamma and IL-12 in allergen-induced early and dual responders with asthma.J Allergy Clin Immunol. 2005 May;115(5):1004-9.

  Yoshida M, Watson RM, Rerecich T, O'Byrne PM.

• Traditional oriental herbal medicine, Bakumondo-to, suppresses vagal neuro-effector transmission in guinea pig trachea.J Asthma. 2003;40(5):497-503.

  Aizawa H, Yoshida M, Inoue H, Hara N.

• Effects of montelukast and budesonide on airway responses and airway inflammation in asthma.Am J Respir Crit Care Med. 2002 Nov 1;166(9):1212-7.

  Leigh R, Vethanayagam D, Yoshida M, Watson RM, Rerecich T, Inman MD, O'Byrne PM.

• Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice.Am J Respir Crit Care Med. 2002 Aug 15;166(4):451-6.

  Yoshida M, Leigh R, Matsumoto K, Wattie J, Ellis R, O'Byrne PM, Inman MD.

• Effect of suplatast tosilate on airway hyperresponsiveness and inflammation in asthma patients.J Asthma. 2002 Sep;39(6):545-52.

  Yoshida M, Aizawa H, Inoue H, Matsumoto K, Koto H, Komori M, Fukuyama S, Okamoto M, Hara N.

• Ozone exposure may enhance airway smooth muscle contraction by increasing Ca(2+) refilling of sarcoplasmic reticulum in guinea pig.Pulm Pharmacol Ther. 2002;15(2):111-19.

  Yoshida M, Aizawa H, Inoue H, Koto H, Nakano H, Komori M, Fukuyama S, Hara N.

• [A case of latex allergy with bronchial asthma].Nihon Kokyuki Gakkai Zasshi. 2000 Nov;38(11):850-3. Japanese.

  Ise S, Yoshida M, Aizawa H, Komori M, Inoue H, Koto H, Hara N.

• Pituitary adenylate cyclase activating peptide mediates inhibitory nonadrenergic noncholinergic relaxation.Eur J Pharmacol. 2000 Apr 21;395(1):77-83.

  Yoshida M, Aizawa H, Takahashi N, Shigyo M, Hara N.

• Once-daily theophylline reduces serum eosinophil cationic protein and eosinophil levels in induced sputum of asthmatics.Int Arch Allergy Immunol. 2000 Feb;121(2):123-8.

  Aizawa H, Iwanaga T, Inoue H, Takata S, Matsumoto K, Takahashi N, Yoshida M, Hara N.

• [Diffuse idiopathic skeletal hyperostosis with fibrobullous change in upper lung lobes and dyspnea due to limitation of thoracic cage]. Nihon Kokyuki Gakkai Zasshi. 1999 Oct;37(10):823-8. Japanese.

  Yoshida M, Kibe A, Aizawa H, Matsumoto K, Inoue H, Koto H, Hara N.

• Effect of endothelin-1 on the serotonin-induced contraction of smooth muscle in the guinea pig trachea.Respiration. 1999;66(1):59-64.

  Yoshida M, Aizawa H, Hara N.

• Effects of thromboxane A2 antagonist on airway hyperresponsiveness, exhaled nitric oxide, and induced sputum eosinophils in asthmatics.Prostaglandins Leukot Essent Fatty Acids. 1998 Sep;59(3):185-90.

  Aizawa H, Inoue H, Nakano H, Matsumoto K, Yoshida M, Fukuyama S, Koto H, Hara N.

• Possible role of cAMP, cGMP and [Ca2+]i during NANC relaxation in the cat airway smooth muscle.J Auton Nerv Syst. 1998 Jan 19;68(1-2):1-13.

  Imoto A, Yoshida M, Takahashi N, Ito Y.

• Mechanisms of vasoconstriction induced by endothelin-1 in smooth muscle of rabbit mesenteric artery.J Physiol. 1994 Jun 1;477 ( Pt 2):253-65.

  Yoshida M, Suzuki A, Itoh T.

著書

• 【共著】「私の治療2019-20、慢性呼吸不全」日本医事新報社

• 【共著】吉田誠：<呼吸器疾患 診断治療アプローチ> 「気管支喘息」項目名：コラム／ディベート　９．喫煙の喘息への影響 中山書店.2017年7月1日発行

• 【分担執筆】吉田　誠：Ⅲ．実際の症例で考える「肺結核後遺症」、日常診療・呼吸ケアに役立つ肺機能、九州肺機能談話会編

• 【分担執筆】吉田　誠：呼吸不全・在宅酸素療法、ガイドライン外来診療2013（第13版）、日経メディカル開発、p440-444、2013/3/25発行

• 【分担執筆】吉田　誠：COPDの最新の治療、福岡市内科医会、内科医誌146：2-6、2013年1月号

その他

• 【学術発表】Makoto Yoshida, Tomoaki Iwanaga, Hiromasa Inoue：European Respiratory Society International Congress 2015、一般演題 ”Effects of tiotropium on lung function in current smokers and never smokers with asthma” （平成27年9月28日、Amsterdam）

• 【学術発表】Makoto Yoshida, Atsushi Moriwaki, Hisayuki Osoreda, Tetsuya Hiramoto, Tomoaki Iwanaga, Hiromasa Inoue：European Respiratory Society International Congress 2018 、一般演題 ”Effects of comorbidities on physical activity in chronic obstructive pulmonary disease”（ 2018/9/18、Paris）