奥村 明之進 おくむら めいのしん 先生

来歴等

略歴

1984年 大阪大学医学部 卒業
1993年 大阪大学医学部 医学博士取得
1993年 大阪大学第一外科 助手
1993年 米国セントルイス　ワシントン大学 留学
1996年 大阪大学第一外科 助手に復職
2002年 国立療養所近畿中央病院 第二呼吸器外科医長
2004年 大阪大学臓器制御外科 講師
2005年 大阪大学外科学講座 准教授
2007年 大阪大学呼吸器外科学 教授
2018年 大阪刀根山医療センター 院長

論文

• Intraoperative pleural lavage cytology in lung cancer patients. The Annals of Thoracic Surgery 51: 599-604, 1991.

  Okumura M, Ohshima S, Kotake Y, Morino H, Kikui M, Yasumitsu T.

• CD45RA-R0+ subset is the major population of dividing thymocytes in the human. European Journal of Immunology 22: 3033-3036, 1992.

  Okumura M, Fujii Y, Inada K, Nakahara K, Matsuda H.

• Both CD45RA+and CD45RA- subpopulations of CD8+ T cells contain cells with high levels of lymphocyte function-associated antigen-1 expression, a phenotype of primed T cells. The Journal of Immunology 150:429-437, 1993.

  Okumura M, Fujii Y, Inada K, Nakahara K, Matsuda H.

• Age-related accumulation of LFA-1high cells in a CD8+CD45RAhigh T cell population. European Journal of Immunology 23:1057-1063, 1993.

  Okumura M, Fujii Y, Takeuchi Y, Inada K, Nakahara K, Matsuda H.

• Regulation of immune function by protein tyrosine phosphatase. Current Opinion in Immunology 7:312-319, 1995.

  Okumura M, Thomas ML.

• Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains. Journal of Immunology 157: 1569-1575, 1996.

  Okumura M, Matthews RJ, Robb B, Litman GW, Bork P, Thomas ML.

• Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA and Cell Biology 17: 779-787, 1998.

  Okumura M, Kung C, Wong S, Rodgers M, Thomas ML.

• Results of surgical treatment of thymomas with special reference to the involved organs. Journal of Thoracic and Cardiovascular Surgery 117: 605-613, 1999.

  Okumura M, Miyoshi S, Takeuchi Y, Yoon H-Y, Minami M, Takeda S, Fujii Y, Nakahara K, Matsuda H.

• 3-color flow cytometric study on lymphocytes derived from thymic diseases. Journal of Surgical Research 101: 130-137, 2001.

  Okumura M, Fujii Y, Miyoshi S, Shiono H, Inoue M, Kadota Y, Fukuhara K, Matsuda H.

• Clinical and functional significance of WHO classification on human thymic epithelial neoplasms: A study of 146 consecutive tumors. The American Journal of Surgical Pathology 25: 103-110, 2001.

  Okumura M, Miyoshi S, Fujii Y, Takeuchi Y, Shiono H, Inoue M, Fukuhara K, Kadota Y, Tateyama H, Eimoto T, Matsuda H.

• The World Health Organization histologic classification reflects oncological behaviors of human thymoma. A clinical study of 273 patients. Cancer 94: 624-632, 2002.

  Okumura M, Ohta M, Tateyama H, Nakagawa K, Matsumura A, Maeda H, Tada H, Eimoto T, Matsuda H, Masaoka A.

• The immunologic role of thymectomy in the treatment of myasthenia gravis. Implication of thymus-associated B lymphocyte subset in reduction of the anti-acetylcholine receptor antibody titer. The Journal of Thoracic and Cardiovascular Surgery. 126: 1922-1928, 2003.

  Okumura M, Ohta M, Takeuchi Y, Shiono H, Inoue M, Fukuhara K, Kadota Y, Miyoshi S, Fujii Y, Matsuda H.

• Outcome of surgical treatment for recurrent thymic epithelial tumors with reference to World Health Organization histologic classification system. Journal of Surgical Oncology 95: 40-44, 2007.

  Okumura M, Shiono H, Inoue M, Tanaka H, Yoon H-E, Nakagawa K, Matsumura A, Ohta M, Iuchi K, Matsuda H.

• Factors associated with outcome of segmentectomy for non-small cell lung cancer: Long-term follow-up study at a single institution in Japan. Lung Cancer 58: 231-237, 2007.

  Okumura M, Goto M, Ideguchi K, Tamura M, Sasaki H, Tanaka H, Matsumura A, Iuchi K.

• Clinical and pathological aspects of thymic epithelial tumors. Gen Thorac Cardiovasc Surg. 56(1):10-16, 2008.

  Okumura M, Shiono H, Minami M, Inoue M, Utsumi T, Kadota Y, Sawa Y.

• Immunological function of thymoma and pathogenesis of paraneoplastic myasthenia gravis. Gen Thorac Cardiovasc Surg. 56(4):143-150, 2008.

  Okumura M, Fujii Y, Shiono H, Inoue M, Minami M, Utsumi T, Kadota Y, Sawa Y.

• Biological implications of thymectomy for myasthenia gravis. Surg Today. 40(2):102-7, 2010.

  Okumura M, Inoue M, Kadota Y, Hayashi A, Tokunaga T, Kusu T, Sawabata N, Shiono H.

• Japanese Joint Committee of Lung Cancer Registry. Differences in the prognosis of resected lung adenocarcinoma according to the histological subtype: a retrospective analysis of Japanese lung cancer registry data. Eur J Cardiothorac Surg. 45(1):100-107, 2014.

  Sakurai H, Asamura H, Miyaoka E, Yoshino I, Fujii Y, Nakanishi Y, Eguchi K, Mori M, Sawabata N, Okumura M, Yokoi K

• for the Japanese Joint Committee of Lung Cancer Registry 2004. Surgery for Small Cell Lung Cancer : A Retrospective Analysis of 243 Patients from Jananese Lung Cancer Registry in 2004. J Thorac Oncol. 9(8):1140-1145, 2014.

  Takei H, Kondo H, Miyaoka E, Asamura H, Yoshino I,Date H, Okumura M, Tada H, Fujii Y, Nakanishi Y, Eguchi K, Dosaka-Akita H, Kobayashi H, Sawabata N, Yokoi K

• Clinicopathological characteristics and surgical results of lung cancer patients aged up to 50 years: The Japanese Lung Cancer Registry Study 2004. Lung Cancer 83(2): 246-251, 2014.

  Inoue M, Okumura M, Sawabata N, Miyaoka E, Asamura H, oshino I, Tada H, Fujii Y, Nakanishi Y, Eguchi K, Mori M, Kobayashi H, Yokoi K.

• Japanese Association for Research of the Thymus. Surgical outcomes of patients with stage III thymoma in the Japanese nation-wide database. Ann Thorac Surg. 100:961–967, 2015.

  Yamada Y, Yoshino I, Nakajima J, Miyoshi S, Ohnuki T, Suzuki M, Nagayasu T, Iwasaki A, Okumura M

• Japanese Association for Research on Thymus. Surgical management of recurrent thymic epithelial tumors. A retrospective analysis based on the Japanese nationwide database. J Thorac Oncol. 10:199–205, 2015.

  Mizuno T, Okumura M, Asamura H, Yoshida K, Niwa H, Kondo K, Horio H, Matsumura A, Yokoi K

• Japanese Joint Committee of Lung Cancer Registry. Surgical intervention for non-small-cell lung cancer patients with pleural carcinomatosis: Results from the Japanese Lung Cancer Registry in 2004. J Thorac Oncol. 10(7):1076-1082, 2015.

  Iida T, Shiba M, Yoshino I, Miyaoka E, Asamura H, Date H, Okumura M, Tada H, Nakanishi Y, Dosaka-Akita H, Kobayashi H, Takahashi K, Inoue M, Yokoi K

• Trends and current status of general thoracic surgery in Japan revealed by review of nationwide databases. J Thorac Dis. 8 (Suppl 8): S589-95, 2016.

  Okumura M.

• Japanese Association for Research on the Thymus (JART). Long-term outcome and prognostic factors of surgically treated thymic carcinoma: results of 306 cases from a Japanese Nationwide Database Study. Eur J Cardiothorac Surg. 49(3):835-841, 2016.

  Hishida T, Nomura S, Yano M, Asamura H, Yamashita M, Ohde Y, Kondo K, Date H, Okumura M, Nagai K

• Japanese Association for Research of Thymus. Myasthenia gravis with thymic epithelial tumour: a retrospective analysis of a Japanese database. Eur J Cardiothorac Surg. 49(5):1510-1515, 2016.

  Nakajima J, Okumura M, Yano M, Date H, Onuki T, Haniuda M, Sano Y

• Minimally invasive surgical procedures for thymic disease in Asia. Journal of Visualized Surgery. 2017.

  Okumura M, Shintani Y, Ohta M, Kadota Y, Inoue M, Shiono H.

• Evolution of Thymic Malignancies Management in Japan. Mediastinum. 2017. doi: 10.21037/med.2017.09.04.

  Okumura M, Shintani Y, Funaki S.

• Advantages of and problems encountered with UICC version 8 TNM staging system for thymic epithelial tumors. Journal of Visualized Surgery. 2018.

  Okumura M.

• Tumour size determines both recurrence-free survival and disease-specific survival after surgical treatment for thymoma. Eur J Cardiothorac Surg. 56:174-181, 2019.

  Okumura M, Yoshino I, Yano M, Watanabe SI, Tsuboi M, Yoshida K, Date H, Yokoi K, Nakajima J, Toyooka SI, Asamura H, Miyaoka E.

著書

• 【共著】Okumura M, Shiono Y, Inoue M, Shintani Y. Novel challenges in myasthenia gravis. Chapter 32. New biological role of thymectomy for myasthenia gravis. Nova Biomedical, New York, 2015.

• 【共著】奥村明之進。縦隔・横隔膜。標準外科学　243-248, 2018. （医学書院、東京）

• 【共著】奥村明之進。胸腺上皮性腫瘍の分類と最新治療。呼吸器内科 34:499-505, 2018.　（科学評論社）

• 【共著】奥村明之進。日本における胸腺外科の進歩と国際社会への貢献。日本胸部外科学会　70年の歩み。354-359, 2018.

• 【共著】奥村明之進。悪性腫瘍領域におけるドラッグリポジショニング。カレント・テラピー　36:414-418, 2018.

その他

• 【受賞】2000年　大阪大学第一外科同窓会 小澤賞

• 【受賞】2013年　第15回World Conference on Lung Cancer（WCLC）, Sydneyで Robert Ginsberg Lectureship Award を受賞

• 【受賞】2018年　第26回European Society of Thoracic Surgeons (ESTS), Ljubljana (Slovenia) で Brompton Prize を受賞