阿古 潤哉 先生のプロフィール

阿古 潤哉 先生

あこ じゅんや

阿古 潤哉 先生

北里大学医学部 循環器内科学 教授

阿古 潤哉 先生のストーリー記事を読む

専門分野

虚血性心疾患、循環器一般

紹介

虚血性心疾患をメインに循環器疾患の全般の診療・研究と、北里大学医学部教授として医師の育成を務める。患者さんのために、をモットーに研究を重ね、世の中を変える医療を目指している。

略歴

1991年 東京大学医学部附属病院 研修医
1992年 三井記念病院内科 循環器科
1996年 東京大学医学部 老年病医員
1997年 同 技官
2000年 同 助手
2001年 スタンフォード大学 心血管コアラボ客員研究員
2006年 同大学 心血管コアラボ Director of Academic Affairs
2009年 自治医科大学附属さいたま医療センター 循環器科 教授
2013年 北里大学医学部 循環器内科学 教授

所属学会・資格・役職など

日本内科学会(総合内科専門医、評議員)
日本循環器学会(循環器専門医、評議員)
日本心臓病学会(FJCC)
日本老年医学会(老年病専門医、評議員)
日本心血管インターベンション治療学会(評議員)
日本心臓リハビリテーション学会(評議員)
日本肺高血圧学会 (評議員)
日本心血管卒中学会(評議員)
国際心血管薬物療法学会(評議員)
日本不整脈学会
日本高血圧学会
日本心不全学会
American College of Cardiology (FACC)
American Heart Association
American Society of Internal Medicine

受賞・著書・論文など

【論文】
1. Eto M, Akishita M, Ishikawa M, Kozaki K, Yoshizumi M, Hashimoto M, Ako J, Sugimoto N, Nagano K, Sudoh N, Toba K, Ouchi Y. Cytokine-induced expression of parathyroid hormone-related peptide in cultured human vascular endothelial cells. Biochem Biophys Res Commun. 1998;249:339-43.

2. Hashimoto M, Akishita M, Eto M, Kozaki K, Ako J, Sugimoto N, Yoshizumi M, Toba K, Ouchi Y. The impairment of flow-mediated vasodilatation in obese men with visceral fat accumulation. Int J Obes Relat Metab Disord. 1998;22:477-84.

3. Iijima K, Yoshizumi M, Ako J, Eto M, Kim S, Hashimoto M, Sugimoto N,

【論文】
1. Eto M, Akishita M, Ishikawa M, Kozaki K, Yoshizumi M, Hashimoto M, Ako J, Sugimoto N, Nagano K, Sudoh N, Toba K, Ouchi Y. Cytokine-induced expression of parathyroid hormone-related peptide in cultured human vascular endothelial cells. Biochem Biophys Res Commun. 1998;249:339-43.

2. Hashimoto M, Akishita M, Eto M, Kozaki K, Ako J, Sugimoto N, Yoshizumi M, Toba K, Ouchi Y. The impairment of flow-mediated vasodilatation in obese men with visceral fat accumulation. Int J Obes Relat Metab Disord. 1998;22:477-84.

3. Iijima K, Yoshizumi M, Ako J, Eto M, Kim S, Hashimoto M, Sugimoto N, Liang YQ, Sudoh N, Toba K, Ouchi Y. Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in rat aortic smooth muscle cells. Biochem Biophys Res Commun. 1998;247:353-6.

4. Yamasaki M, Hara K, Ikari Y, Kobayashi N, Kozuma K, Ohmoto Y, Oh-Hashi Y, Ako J, Nakajima H, Chiku N, Saeki F, Tamura T. Effects of cilostazol on late lumen loss after Palmaz-Schatz stent implantation. Cathet Cardiovasc Diagn. 1998;44:387-91.

5. Hashimoto M, Eto M, Akishita M, Kozaki K, Ako J, Iijima K, Kim S, Toba K, Yoshizumi M, Ouchi Y. Correlation between flow-mediated vasodilatation of the brachial artery and intima-media thickness in the carotid artery in men. Arterioscler Thromb Vasc Biol. 1999;19:2795-800.

6. Ako J, Eto M, Kim S, Iijima K, Watanabe T, Ohike Y, Yoshizumi M, Ouchi Y. Pericardial constriction due to malignant lymphoma. Jpn Heart J. 2000;41:673-9.

7. Hashimoto M, Kozaki K, Eto M, Akishita M, Ako J, Iijima K, Kim S, Toba K, Yoshizumi M, Ouchi Y. Association of coronary risk factors and endothelium-dependent flow-mediated dilatation of the brachial artery. Hypertens Res. 2000;23:233-8.

8. Iijima K, Yoshizumi M, Hashimoto M, Kim S, Eto M, Ako J, Liang YQ, Sudoh N, Hosoda K, Nakahara K, Toba K, Ouchi Y. Red wine polyphenols inhibit proliferation of vascular smooth muscle cells and downregulate expression of cyclin A gene. Circulation. 2000;101:805-11.

9. Nagano K, Toba K, Akishita M, Watanabe T, Kozaki K, Eto M, Hashimoto M, Sudoh N, Ako J, Yoshizumi M, Ouchi Y. Prostanoids regulate proliferation of vascular smooth muscle cells induced by arginine vasopressin. Eur J Pharmacol. 2000;389:25-33.

10. Ako J, Takenaka K, Uno K, Nakamura F, Shoji T, Iijima K, Ohike Y, Kim S, Watanabe T, Yoshizumi M, Ouchi Y. Reversible left ventricular systolic dysfunction - Reversibility of coronary microvascular abnormality. Jpn Heart J. 2001;42:355-363.

11. Ako J, Eto M, Watanabe T, Ouchi Y. A case of severe hypoglycemia due to pimobendan. Int J Cardiol. 2001;80:83-4.

12. Hashimoto M, Kim S, Eto M, Iijima K, Ako J, Yoshizumi M, Akishita M, Kondo K, Itakura H, Hosoda K, Toba K, Ouchi Y. Effect of acute intake of red wine on flow-mediated vasodilatation of the brachial artery. Am J Cardiol. 2001;88:1457-60, A9.

13. Sudoh N, Toba K, Akishita M, Ako J, Hashimoto M, Iijima K, Kim S, Liang YQ, Ohike Y, Watanabe T, Yamazaki I, Yoshizumi M, Eto M, Ouchi Y. Estrogen prevents oxidative stress-induced endothelial cell apoptosis in rats. Circulation. 2001;103:724-9.

14. Watanabe T, Yoshizumi M, Akishita M, Eto M, Toba K, Hashimoto M, Nagano K, Liang YQ, Ohike Y, Iijima K, Sudoh N, Kim S, Nakaoka T, Yamashita N, Ako J, Ouchi Y. Induction of nuclear orphan receptor NGFI-B gene and apoptosis in rat vascular smooth muscle cells treated with pyrrolidinedithiocarbamate. Arterioscler Thromb Vasc Biol. 2001;21:1738-44.

15. Ako J, Sagawa K, Iijima K, Ohike Y, Watanabe T, Kozaki K, Yoshizumi M, Ouchi Y. Senile cardiac amyloidosis. Geriatrics and Gerontology International. 2001;1:65-8.

16. Ako J, Kozaki K, Yoshizumi M, Ouchi Y. Transient left ventricular apical ballooning without coronary artery stenosis: a form of stunning-like phenomenon? J Am Coll Cardiol. 2002;39:741-2.

17. Iijima K, Yoshizumi M, Hashimoto M, Akishita M, Kozaki K, Ako J, Watanabe T, Ohike Y, Son B, Yu J, Nakahara K, Ouchi Y. Red wine polyphenols inhibit vascular smooth muscle cell migration through two distinct signaling pathways. Circulation. 2002;105:2404-10.

18. Liang YQ, Akishita M, Kim S, Ako J, Hashimoto M, Iijima K, Ohike Y, Watanabe T, Sudoh N, Toba K, Yoshizumi M, Ouchi Y. Estrogen receptor beta is involved in the anorectic action of estrogen. Int J Obes Relat Metab Disord. 2002;26:1103-9.

19. Sahara M, Inoue S, Sunaga S, Kitagawa H, Ako J, Hoshino S, Toba K, Ouchi Y. Megakaryoblastic transformation of chronic myelomonocytic leukemia presenting with severe bone pain. Geriatrics and Gerontology International. 2002;2:105-9.

20. Amiya E, Ako J, Kozaki K, Iijima K, Nagase T, Ouchi Y. Yellow nail syndrome in an elderly man. Geriatrics and Gerontology International. 2002;2:157-60.

21. Sata M, Takahashi A, Tanaka K, Washida M, Ishizaka N, Ako J, Yoshizumi M, Ouchi Y, Taniguchi T, Hirata Y, Yokoyama M, Nagai R, Walsh K. Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway. Arterioscler Thromb Vasc Biol. 2002;22:1305-9.

22. Ako M, Kawara T, Uchida S, Miyazaki S, Nishihara K, Mukai J, Hirao K, Ako J, Okubo Y. Correlation between electroencephalography and heart rate variability during sleep. Psychiatry Clin Neurosci. 2003;57:59-65.

23. Ako J, Honda Y, Fitzgerald PJ. Tako-tsubo-like left ventricular dysfunction. Circulation. 2003;108:e158.

24. Ako J, Ikari Y, Hatori M, Hara K, Ouchi Y. Changing spectrum of infective endocarditis - Review of 194 episodes over 20 years. Circ J. 2003;67:3-7.

25. Daida H, Ouchi Y, Saito Y, Yamada N, Nishide T, Mokuno H, Kurata T, Sato H, Eto M, Ako JY, Tango T, Yamaguchi H. Preventing angiographic progression of coronary atherosclerosis with pravastatin. J Atheroscler Thromb. 2003;10:25-31.

26. Ako J, Honda Y, Fitzgerald PJ. Conditions associated with ST-segment elevation. N Engl J Med. 2004;350:1152-5.

27. Sonoda S, Morino Y, Ako J, Terashima M, Hassan AH, Bonneau HN, Leon MB, Moses JW, Yock PG, Honda Y, Kuntz RE, Fitzgerald PJ. Impact of final stent dimensions on long-term results following sirolimus-eluting stent implantation: serial intravascular ultrasound analysis from the sirius trial. J Am Coll Cardiol. 2004;43:1959-63.

28. Farouque HM, Kaltenbach T. Ako J. Tremmel JA, Fearon WF, Yeung AC, Vagelos. “Tako-tsubo-like left ventricular dysfunction”: a clinical entity mimicking acute myocardial infarction with a favorable prognosis. Am J Geriatr Cardiol. 2004;13:323-6.

29. Ako J, Honda Y, Fitzgerald PJ. Impending coronary perforation after cutting balloon angioplasty. Heart. 2004;91:e8.

30. Kaneda H, Ako J, Fitzgerald PJ. Peripartum dissection of the right coronary artery. N Engl J Med. 2005;352:1048-1049.

31. Eto M, Toba K, Akishita M, Kozaki K, Watanabe T, Kim S, Hashimoto M, Ako J, Iijima K, Sudoh N, Yoshizumi M, Ouchi Y. Impact of blood pressure variability on cardiovascular events in elderly patients with hypertension. Hypertens Res. 2005;28:1-7.

32. Ako J, Honda Y, Fitzgerald PJ. Transient left ventricular apical ballooning. Ann Intern Med. 2005;142:678.

33. Kaneda H, Ako J, Kataoka T, Miyazawa A, Terashima M, Ikeno F, Sonoda S, Shimada Y, Morino Y, Honda Y, Yock PG, Fitzgerald PJ. Effect of lumen narrowing within coronary stents on proximal and distal vessel segments following bare metal stent implantation. Am J Cardiol. 2005;96:376-378.

34. Ako J, Morino Y, Honda Y, Hassan A, Sonoda S, Yock PG, Leon MB, Moses JW, Bonneau HN, Fitzgerald PJ. Late incomplete stent apposition after sirolimus-eluting stent implantation a serial intravascular ultrasound analysis. J Am Coll Cardiol. 2005;46:1002-1005.

35. Sakurai R, Ako J, Morino Y, Sonoda S, Kaneda K, Terashima M, Hassan A, Leon MB, Moses JW, Popma JP, Bonneau HN, Yock PG, Fitzgerald PJ, Honda Y, Investigators tST. Predictors of edge stenosis following sirolimus-eluting Stent Deployment (A quantitative intravascular ultrasound analysis from the SIRIUS trial). Am J Cardiol. 2005;96;1251-1253.

36. Kaneda H, Koizumi T, Ako J, Terashima M, Morino Y, Honda Y, Yock PG, Leon MB, Moses JW, Fitzgerald PJ, investigators. Impact of intravascular ultrasound lesion characteristics on neointimal hyperplasia following sirolimus-eluting stent implantation. Am J Cardiol. 2005;96;1237-1241.

37. Kaneda H, Ako J, Honda Y, Terashima M, Morino Y, Yock PG, Popma JP, Leon MB, Moses JW, Fitzgerald PJ.. Impact of asymmetric stent expansion on neointimal hyperplasia following sirolimus-eluting stent implantation. Am J Cardiol. 2005:96;1404-1407.

38. Kaneda H, Ako J, Kataoka T, Takahashi T, Terashima M, Waseda K, Miyazawa A, Hassan A, Honda Y, Yock PG, Fitzgerald PJ. Heterogeneity of neointimal distribution of instent restenosis in patients with diabetes mellitus. Am J Cardiol. 2005:97;340-342.

39. Ako J, Sudhir K, Farouque HM, Honda Y, Fitzgerald PJ. Transient left ventricular dysfunction under severe stress: Brain-heart relationship revisited. Am J Medicine. 2006:119;10-17.

40. Hirohata A, Morino Y, Ako J, Sakurai R, Buchbinder M, Caputo RP, Karas SP, Mishkel GJ, Mooney MR, O'Shaughnessy C D, Raizner AE, Wilensky RL, Williams DO, Wong SC, Yock PG, Honda Y, Moses JW, Fitzgerald PJ. Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial). Am J Cardiol. 2006;98(11):1464-1467.

41. Kaneda H, Ako J, Kataoka T, Takahashi T, Terashima M, Waseda K, Miyazawa A, Hassan A, Honda Y, Yock PG, Fitzgerald PJ. Heterogeneity of neointimal distribution of in-stent restenosis in patients with diabetes mellitus. Am J Cardiol. 2006;97:340-342.

42. Waseda K, Ozaki Y, Takashima H, Ako J, Yasukawa T, Ismail TF, Hishida H, Ito T. Impact of angiotensin II receptor blockers on the progression and regression of coronary atherosclerosis: an intravascular ultrasound study. Circ J. 2006;70:1111-1115.

43. Kaneda H, Ako J, Kataoka T, Takahashi T, Terashima M, Waseda K, Miyazawa A, Hassan AH, Honda Y, Yock PG, Fitzgerald PJ. Impact of gender on neointimal hyperplasia following coronary artery stenting. Am J Cardiol. 2007;99:491-493.

44. Waseda K, Ako J, Shimada Y, Morino Y, Tsujino I, Hongo Y, Sudhir K, Yock PG, Fitzgerald PJ, Honda Y. Comparison of vessel response following sirolimus-eluting stent implantation as assessed by serial 3-D intravascular ultrasound study. J Invasive Cardiol 2007;19:171-3.

45. Tsujino I, Ako J, Honda Y, Fitzgerald PJ. Drug delivery via nano-, micro and macroporous coronary stent surfaces. Expert Opin Drug Deliv 2007;4:287-95.

46. Sakurai R, Ako J, Hassan AH, Bonneau HN, Neumann FJ, Desmet W, Holmes DR, Jr., Yock PG, Fitzgerald PJ, Honda Y. Neointimal progression and luminal narrowing in sirolimus-eluting stent treatment for bare metal in-stent restenosis: a quantitative intravascular ultrasound analysis. Am Heart J 2007;154:361-5.

47. Sakakura K, Kubo N, Ako J, Ikeda N, Funayama H, Hirahara T, Sugawara Y, Yasu T, Kawakami M, Momomura S. Determinants of in-hospital death and rupture in patients with a Stanford B aortic dissection. Circ J 2007;71:1521-4.

48. Nakamura T, Kubo N, Ako J, Momomura S. Angiographic no-reflow phenomenon and plaque characteristics by virtual histology intravascular ultrasound in patients with acute myocardial infarction. J Interv Cardiol 2007;20:335-9.

49. Miyazawa A, Tsujino I, Ako J, Shimada Y, Courtney BK, Sakurai R, Nakamura M, Okura H, Waseda K, Honda Y, Fitzgerald PJ. Characterization of late incomplete stent apposition: a comparison among bare-metal stents, intracoronary radiation and sirolimus-eluting stents. J Invasive Cardiol 2007;19:515-8.

50. Miyazawa A, Ako J, Hassan A, Hasegawa T, Abizaid A, Verheye S, McClean D, Neumann FJ, Grube E, Honda Y, Fitzgerald PJ. Analysis of bifurcation lesions treated with novel drug-eluting dedicated bifurcation stent system: Intravascular ultrasound results of the AXXESS PLUS trial. Catheter Cardiovasc Interv 2007;70:952-7.

51. Kojima T, Ako J, Eto M, Iijima K, Akishita M, Ouchi Y. Tako-tsubo-like left ventricular dysfunction in a patient with chronic total occlusion of the left anterior descending artery. Int J Cardiol 2007;119:e19-21.

52. Waseda K, Ako J, Kaneda H, Miyazawa A, Shimada Y, Morino Y, Honda Y, Fitzgerald PJ. Effect of lumen narrowing within sirolimus-eluting stents on proximal and distal vessel segments. Circ J 2008;72:534-7.

53. Miyazawa A, Ako J, Hongo Y, Hur SH, Tsujino I, Courtney BK, Hassan AH, Kandzari DE, Honda Y, Fitzgerald PJ. Comparison of vascular response to zotarolimus-eluting stent versus sirolimus-eluting stent: intravascular ultrasound results from ENDEAVOR III. Am Heart J 2008;155:108-13.

55. Kaneda H, Kataoka T, Ako J, Honda Y, Yock PG, Fitzgerald PJ. Coronary risk factors and coronary atheroma burden at severely narrowing segments. Int J Cardiol 2008;124:124-6.

56. Ako J. Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy). Chest 2008;133:1052.

57. Yamasaki M, Ako J, Honda Y, Hassan A, Koo B, Abizaid A, Fitzgerald P, Whitbourn R. Novel guidewire-based stent delivery system: examination by intravascular ultrasound. Catheter Cardiovasc Interv 2008;72:47-51.

58. Kaneda H, Ako J, Terashima M, Waseda K, Yock PG, Fitzgerald PJ. Distribution pattern of neointimal hyperplasia following sirolimus-eluting stent implantation assessed by 3-dimensional intravascular ultrasound. Int J Cardiol 2008 [Epub].

59. Sakakura K, Kubo N, Hashimoto S, Ikeda N, Funayama H, Hirahara T, Sugawara Y, Yasu T, Ako J, Kawakami M, Momomura S. Determinants of in-hospital death in left main coronary artery myocardial infarction complicated by cardiogenic shock. J Cardiol 2008;52:24-9.

60. Hur SH, Ako J, Shimada Y, Tsujino I, Hassan AH, Abizaid A, Shiran A, Lewis BS, Guagliumi G, Cohen SA, Honda Y, Fitzgerald PJ, Sousa JE. Two-year intravascular ultrasound observations in diabetic patients treated with single and double dose sirolimus-eluting stents: results of the double dose diabetes (3D) study. J Invasive Cardiol 2008;20:411-6.

61. Iwata H, Ako J, Nagai R. Recurrence of late-acquired incomplete stent apposition following sirolimus-eluting stent implantation. J Invasive Cardiol 2008;20:E265-8.

62. Kaneda H, Ako J, Terashima M, Morino Y, Honda Y, Yock PG, Leon MB, Moses JW, Fitzgerald PJ. Sirolimus-eluting stent implantation in small coronary arteries: A three dimensional intravascular ultrasound study from the SIRIUS trial. Int J Cardiol 2008. [Epub]

63. Koo BK, Yamasaki M, Ako J, Waseda K, Honda Y, Fitzgerald PJ, Abizaid A, Whitbourn RJ. Intravascular ultrasound analysis of small-vessel lesions treated with novel ultra-low profile, guidewire-based self-expanding stent system. J Invasive Cardiol 2008;20:647-50.

64. Hasegawa T, Ako J, Koo BK, Miyazawa A, Sakurai R, Chang H, Dens J, Verheye S, Grube E, Honda Y, Fitzgerald PJ. Analysis of left main coronary artery bifurcation lesions treated with biolimus-eluting DEVAX AXXESS plus nitinol self-expanding stent: intravascular ultrasound results of the AXXENT trial. Catheter Cardiovasc Interv 2009;73:34-41.

65. Grube E, Sievert H, Hauptmann KE, Mueller R, Gerckens U, Buellesfeld L, Ako J, Shimohama T, Costa M, Fitzgerald P. Novel drug eluting stent system for customised treatment of coronary lesions: CUSTOM I feasibility trial 24 month results. EuroIntervention 2008;4:71-6.

66. Sakakura K, Kubo N, Ako J, Fujiwara N, Funayama H, Ikeda N, Nakamura T, Sugawara Y, Yasu T, Kawakami M, Momomura S. Determinants of long-term mortality in patients with type B acute aortic dissection. Am J Hypertens 2009;22:371-7.

67. Nakamura T, Ako J, Kadowaki T, Funayama H, Sugawara Y, Kubo N, Momomura S. Impact of acute hyperglycemia during primary stent implantation in patients with ST-elevation myocardial infarction. J Cardiol 2009;53:272-7.

68. Waseda K, Ako J, Hasegawa T, Shimada Y, Ikeno F, Ishikawa T, Demura Y, Hatada K, Yock PG, Honda Y, Fitzgerald PJ. Intraoperative fluorescence imaging system for on-site assessment of off-pump coronary artery bypass graft. J Am Coll Coardiol Img 2009; 2: 604-12.

69. Hattori T, Sakakura K, Kubo N, Ako J, Sugawara Y, Funayama H, Matsuzaki S, Nakamura T, Hirahara T, Wada H, Kawakami M, Momomura S. Venous thrombus formation following percutaneous cardiopulmonary support. J Cardiol 2009;54:490-3.

70. Ogita M, Nakamura T, Fujiwara N, Sakakura K, Funayama H, Sugawara Y, Kubo N, Ako J, Momomura S. Long-term clinical follow-up after sirolimus-eluting stent versus bare metal stent implantation in patients with acute coronary syndrome. J Interv Cardiol 2009;22:216-21.

71. Otake H, Shite J, Ako J, Shinke T, Tanino Y, Ogasawara D, Sawada T, Miyoshi N, Kato H, Koo BK, Honda Y, Fitzgerald PJ, Hirata K. Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography. JACC Cardiovasc Interv 2009;2:459-66.

72. Ota H, Eto M, Ako J, Ogawa S, Iijima K, Akishita M, Ouchi Y. Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation. J Am Coll Cardiol 2009;53:2298-305.

73. Waseda K, Miyazawa A, Ako J, Hasegawa T, Tsujino I, Sakurai R, Yock PG, Honda Y, Kandzari DE, Leon MB, Fitzgerald PJ. Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. JACC Cardiovasc Interv 2009;2:779-84.

74. Sakakura K, Kubo N, Ako J, Ikeda N, Funayama H, Hirahara T, Wada H, Sugawara Y, Yasu T, Kawakami M, Momomura S. Clinical features of early recurrent myocardial infarction. Heart Vessels 2009;24:347-51.

76. Ogita M, Funayama H, Nakamura T, Sakakura K, Sugawara Y, Kubo N, Ako J, Ishikawa SE, Momomura S. Plaque characterization of non-culprit lesions by virtual histology intravascular ultrasound in diabetic patients: impact of renal function. J Cardiol 2009;54:59-65.

77. Nakatani D, Ako J, Yamasaki M, Shimohama T, Hasegawa T, Otake H, Waseda K, Tsujino I, Sakurai R, Koo BK, Chang H, Yock PG, Sudhir K, Pierson W, Stone GW, Saito S, Honda Y, Fitzgerald PJ. Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation. J Invasive Cardiol 2009;21:613-7.

78. Nakamura T, Kubo N, Funayama H, Sugawara Y, Ako J, Momomura S. Plaque characteristics of the coronary segment proximal to the culprit lesion in stable and unstable patients. Clin Cardiol 2009;32:E9-12.

79. Nakamura T, Ako J, Kadowaki T, Funayama H, Sugawara Y, Kubo N, Momomura S. Impact of acute hyperglycemia during primary stent implantation in patients with ST-elevation myocardial infarction. J Cardiol 2009;53:272-7.

80. Kaneda H, Ako J, Terashima M, Waseda K, Yock PG, Fitzgerald PJ. Distribution pattern of neointimal hyperplasia following sirolimus-eluting stent implantation assessed by 3-dimensional intravascular ultrasound. Int J Cardiol 2009;135:243-5.

81. Hur SH, Ako J, Honda Y, Sudhir K, Fitzgerald PJ. Late-acquired incomplete stent apposition: morphologic characterization. Cardiovasc Revasc Med 2009;10:236-46.

82. Hasegawa T, Ako J, Koo BK, Miyazawa A, Sakurai R, Chang H, Dens J, Verheye S, Grube E, Honda Y, Fitzgerald PJ. Analysis of Left Main Coronary Artery Bifurcation Lesions Treated With Biolimus-Eluting DEVAX AXXESS Plus Nitinol Self-Expanding Stent: Intravascular Ultrasound Results of the AXXENT Trial. Catheterization and Cardiovascular Interventions 2009;73:34-41.

83. Chang H, Hassan AH, Kim YL, Lloyd LJ, Koo BK, Ako J, Honda Y, Davidson CJ, Fitzgerald PJ. A Novel Technique for Endovascular Detection and Removal of Radiographic Contrast during Angiography. J Invasive Cardiol 2009;21:314-8.

84. Yoshioka T, Funayama H, Hoshino H, Nakamura T, Sugawara Y, Kubo N, Nagata O, Ako J, Ishikawa SE, Kawakami M, Momomura S. Association of CD40 ligand levels in the culprit coronary arteries with subsequent prognosis of acute myocardial infarction. Atherosclerosis 2010;213:268-72.

85. Waseda K, Hasegawa T, Ako J, Honda Y, Grube E, Whitbourn R, Ormiston J, O'Shaughnessy CD, Henry TD, Overlie P, Schwartz LB, Sudhir K, Chevalier B, Gray WA, Yeung AC, Fitzgerald PJ. Comparison of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation: pooled IVUS results from the ZoMaxx I and II trials. Circ J 2010;74:2334-9.

86. Waseda K, Ako J, Yamasaki M, Koizumi T, Ormiston J, Worthley SG, Whitbourn RJ, Walters DL, Honda Y, Meredith IT, Fitzgerald PJ. Short- and mid-term intravascular ultrasound analysis of the new zotarolimus-eluting stent with durable polymer - results from the RESOLUTE trial. Circ J 2010;74:2097-102.

87. Ueba H, Brines M, Yamin M, Umemoto T, Ako J, Momomura S, Cerami A, Kawakami M. Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin. Proc Natl Acad Sci U S A 2010;107:14357-62.

88. Shimohama T, Ako J, Yamasaki M, Otake H, Tsujino I, Hasegawa T, Nakatani D, Sakurai R, Chang H, Kusano H, Waseda K, Honda Y, Stone GW, Saito S, Fitzgerald PJ, Sudhir K. SPIRIT III JAPAN versus SPIRIT III USA: a comparative intravascular ultrasound analysis of the everolimus-eluting stent. Am J Cardiol 2010;106:13-7.

89. Sakakura K, Kubo N, Ako J, Wada H, Fujiwara N, Funayama H, Ikeda N, Nakamura T, Sugawara Y, Yasu T, Kawakami M, Momomura S. Peak C-reactive protein level predicts long-term outcomes in type B acute aortic dissection. Hypertension 2010;55:422-9.

90. Otake H, Shite J, Ikeno F, Shinke T, Teramoto T, Miyoshi N, Ako J, Honda Y, Fitzgerald PJ, Hirata KI. Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: Insights from an optical coherence tomography study in humans. Int J Cardiol 2010, Epub.

91. Otake H, Honda Y, Yamasaki M, Tsujino I, Shimohama T, Sakurai R, Hasegawa T, Waseda K, Ako J, Fitzgerald PJ. Vascular response to overlapping everolimus-eluting stents. - Comparison with paclitaxel-eluting stents. Circ J 2010;74:1023-5.

92. Otake H, Ako J, Yamasaki M, Tsujino I, Shimohama T, Hasegawa T, Sakurai R, Waseda K, Honda Y, Sood P, Sudhir K, Stone GW, Fitzgerald PJ. Comparison of everolimus- versus paclitaxel-eluting stents implanted in patients with diabetes mellitus as evaluated by three-dimensional intravascular ultrasound analysis. Am J Cardiol 2010;106:492-7.

93. Otake H, Ako J, Waseda K, Sakurai R, Hirohata A, Kaneda H, Hasegawa T, Honda Y, Fitzgerald PJ. Neointimal hyperplasia in a thin-strut cobalt-chromium stent: insights from detailed 3-D intravascular ultrasound analysis. Int J Cardiol 2010;145:125-6.

94. Nakamura T, Ogita M, Ako J, Momomura S. Gender differences of plaque characteristics in elderly patients with stable angina pectoris: an intravascular ultrasonic radiofrequency data analysis. Int J Vasc Med 2010;2010:134692.

95. Koo BK, Waseda K, Ako J, Hasegawa T, Shimohama T, Nakatani D, Otake H, Yamasaki M, Sakurai R, Tsujino I, Honda Y, Fitzgerald PJ. Incidence of diffuse and focal chronic stent recoil after implantation of current generation bare-metal and drug-eluting stents. Int J Cardiol 2010;144:132-4.

96. Kaneda H, Ako J, Terashima M, Morino Y, Honda Y, Yock PG, Leon MB, Moses JW, Fitzgerald PJ. Sirolimus-eluting stent implantation in small coronary arteries: a three dimensional intravascular ultrasound study from the SIRIUS trial. Int J Cardiol 2010;138:126-30.

97. Kaneda H, Ako J, Terashima M. Serial intravascular ultrasound examinations and clinical outcome. J Am Coll Cardiol 2010;56:1764.

98. Hassan AH, Ako J, Waseda K, Honda Y, Zeller T, Leon MB, Fitzgerald PJ. Mechanism of lumen gain with a novel rotational aspiration atherectomy system for peripheral arterial disease: examination by intravascular ultrasound. Cardiovasc Revasc Med 2010;11:155-8.

99. Arao K, Yasu T, Ohmura N, Tsukamoto Y, Murata M, Kubo N, Umemoto T, Ikeda N, Ako J, Ishikawa SE, Kawakami M, Momomura S. Circulating CD34+/133+ progenitor cells in patients with stable angina pectoris undergoing percutaneous coronary intervention. Circ J 2010;74:1929-35.

100. Ako J, Momomura S. Regression-resistant plaque in diabetic patients. Circ J 2010;74:1073-4.

101. Waseda K, Ako J, Yamasaki M, Koizumi T, Sakurai R, Hongo Y, Koo BK, Ormiston J, Worthley SG, Whitbourn RJ, Walters DL, Meredith IT, Fitzgerald PJ, Honda Y. Impact of polymer formulations on neointimal proliferation after zotarolimus-eluting stent with different polymers: insights from the RESOLUTE trial. Circ Cardiovasc Interv 2011;4:248-55.

102. Tada Y, Nakamura T, Funayama H, Sugawara Y, Ako J, Ishikawa SE, Momomura S. Early development of hyponatremia implicates short- and long-term outcomes in ST-elevation acute myocardial infarction. Circ J 2011;75:1927-33.

103. Seguchi M, Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Yamaguchi A, Ako J, Momomura S. Idiopathic pulmonary artery aneurysm. Circulation 2011;124:e369-70.

104. Sakakura K, Ako J, Wada H, Kubo N, Momomura SI. ACC/AHA classification of coronary lesions reflects medical resource use in current percutaneous coronary interventions. Catheter Cardiovasc Interv 2011.

105. Sakakura K, Ako J, Wada H, Kubo N, Momomura S. Comparison of the resource utilization between simultaneous strategy and staged strategy to treat two-vessel coronary artery disease by percutaneous coronary intervention. J Invasive Cardiol 2011;23:454-9.

106. Sakakura K, Ako J, Momomura S. Successful removal of an entrapped rotablation burr by extracting drive shaft sheath followed by balloon dilatation. Catheter Cardiovasc Interv 2011;78:567-70.

107. Otake H, Honda Y, Courtney BK, Shimohama T, Ako J, Waseda K, Macours N, Rogers C, Popma JJ, Abizaid A, Ormiston JA, Spaulding C, Cohen SA, Fitzgerald PJ. Intravascular ultrasound results from the NEVO ResElution-I trial: a randomized, blinded comparison of sirolimus-eluting NEVO stents with paclitaxel-eluting TAXUS Liberte stents in de novo native coronary artery lesions. Circ Cardiovasc Interv 2011;4:146-54.

108. Ogita M, Sakakura K, Nakamura T, Funayama H, Wada H, Naito R, Sugawara Y, Kubo N, Ako J, Momomura SI. Association between deteriorated renal function and long-term clinical outcomes after percutaneous coronary intervention. Heart Vessels 2011.

109. Ogita M, Ako J, Sakakura K, Nakamura T, Funayama H, Sugawara Y, Kubo N, Momomura S. Distal reference segment luminal gain following percutaneous coronary intervention for chronic total occlusion. Int Heart J 2011;52:270-3.

110. Nishida T, Sakakura K, Wada H, Ikeda N, Sugawara Y, Kubo N, Ako J, Momomura SI. Determinants of in-hospital death in patients with postinfarction ventricular septal perforation. Heart Vessels 2011.

111. Nakatani D, Ako J, Tremmel JA, Waseda K, Otake H, Koo BK, Miyazawa A, Hongo Y, Hur SH, Sakurai R, Yock PG, Honda Y, Fitzgerald PJ. Sex differences in neointimal hyperplasia following endeavor zotarolimus-eluting stent implantation. Am J Cardiol 2011;108:912-7.

112. Naito R, Sakakura K, Kasai T, Dohi T, Wada H, Sugawara Y, Kubo N, Yamashita S, Narui K, Ishiwata S, Ohno M, Ako J, Momomura SI. Aortic dissection is associated with intermittent hypoxia and re-oxygenation. Heart Vessels 2011.

113. Kaneda H, Ako J, Terashima M. Intravascular ultrasound imaging for assessing regression and progression in coronary artery disease. Am J Cardiol 2011;106:1735-46.

114. Hoshina M, Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Yasu T, Ako J, Momomura SI. Determinants of progression of aortic valve stenosis and outcome of adverse events in hemodialysis patients. J Cardiol 2011.

115. Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, Nakano T, Ohashi Y, Ito H. Non-high-density lipoprotein cholesterol: An important predictor of stroke and diabetes-related mortality in japanese elderly diabetic patients. Geriatrics & gerontology international. 2012;12 Suppl 1:18-28

116. Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, Nakano T, Ohashi Y, Ito H. Long-term multiple risk factor interventions in japanese elderly diabetic patients: The japanese elderly diabetes intervention trial--study design, baseline characteristics and effects of intervention. Geriatrics & gerontology international. 2012;12 Suppl 1:7-17

117. Fujiwara T, Sakakura K, Ako J, Wada H, Arao K, Sugawara Y, Momomura S. Occurrence of late acquired peri-stent contrast staining: Comparison between sirolimus-eluting stents and everolimus-eluting stents. International heart journal. 2012;53:165-169

118. Hoshina M, Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Yasu T, Ako J, Momomura S. Determinants of progression of aortic valve stenosis and outcome of adverse events in hemodialysis patients. Journal of cardiology. 2012;59:78-83

119. Jinnouchi H, Sakakura K, Wada H, Kubo N, Sugawara Y, Nakamura T, Funayama H, Ako J, Momomura S. Transradial percutaneous coronary intervention for acute myocardial infarction reduces ccu stay in patients 80 or older. International heart journal. 2012;53:79-84

120. Kume T, Waseda K, Ako J, Sakata K, Yamasaki M, Shimohama T, Tsujino I, Hasegawa T, Fitzgerald PJ, Honda Y. Intravascular ultrasound assessment of postprocedural incomplete stent apposition. J Invasive Cardiol. 2012;24:13-16

121. Mori M, Sakakura K, Wada H, Ikeda N, Jinnouchi H, Sugawara Y, Kubo N, Momomura SI, Ako J. Left ventricular apical aneurysm following primary percutaneous coronary intervention. Heart and vessels. 2012

122. Naito R, Sakakura K, Kasai T, Dohi T, Wada H, Sugawara Y, Kubo N, Yamashita S, Narui K, Ishiwata S, Ohno M, Ako J, Momomura S. Aortic dissection is associated with intermittent hypoxia and re-oxygenation. Heart and vessels. 2012;27:265-270

123. Naito R, Sakakura K, Wada H, Funayama H, Sugawara Y, Kubo N, Ako J, Momomura S. Mid-term clinical outcomes of acs and non-acs patients treated with everolimus-eluting stents. International heart journal. 2012;53:215-220

124. Naito R, Sakakura K, Wada H, Funayama H, Sugawara Y, Kubo N, Ako J, Momomura S. Comparison of long-term clinical outcomes between sirolimus-eluting stents and paclitaxel-eluting stents following rotational atherectomy. International heart journal. 2012;53:149-153

125. Nishida T, Sakakura K, Wada H, Ikeda N, Sugawara Y, Kubo N, Ako J, Momomura S. Determinants of in-hospital death in patients with postinfarction ventricular septal perforation. Heart and vessels. 2012;27:475-479

126. Ogita M, Sakakura K, Nakamura T, Funayama H, Wada H, Naito R, Sugawara Y, Kubo N, Ako J, Momomura S. Association between deteriorated renal function and long-term clinical outcomes after percutaneous coronary intervention. Heart and vessels. 2012;27:460-467

127. Otake H, Shite J, Ikeno F, Shinke T, Teramoto T, Miyoshi N, Ako J, Honda Y, Fitzgerald PJ, Hirata K. Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: Insights from an optical coherence tomography study in humans. Int J Cardiol. 2012;157:38-42

128. Sakakura K, Ako J, Wada H, Kubo N, Momomura S. Acc/aha classification of coronary lesions reflects medical resource use in current percutaneous coronary interventions. Catheter Cardiovasc Interv. 2012;80:370-376

129. Sakakura K, Ako J, Wada H, Naito R, Arao K, Funayama H, Kubo N, Momomura S. Beta-blocker use is not associated with slow flow during rotational atherectomy. J Invasive Cardiol. 2012;24:379-384

130. Sakakura K, Ako J, Wada H, Naito R, Funayama H, Arao K, Kubo N, Momomura S. Comparison of frequency of complications with on-label versus off-label use of rotational atherectomy. Am J Cardiol. 2012;110:498-501

131. Sasai H, Sakakura K, Wada H, Sugawara Y, Ako J, Momomura S. Stiff coronary stenosis in a young female with pseudoxanthoma elasticum. Jacc Interv. 2012;5:112-113

132. Satomura H, Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Ako J, Momomura S. Congestive heart failure in the elderly: Comparison between reduced ejection fraction and preserved ejection fraction. Journal of cardiology. 2012;59:215-219

133. Tsujino I, Koizumi T, Shimohama T, Ako J, Waseda K, Krucoff M, Honda Y, Fitzgerald PJ. Intravascular ultrasound insights from the cobalt chromium stent with antiproliferative for restenosis ii (costar ii) trial comparing costar and taxus paclitaxel-eluting stents. Cardiovasc Revasc Med. 2012;13:111-118

134. Wada H, Sakakura K, Ako J, Momomura S. Stenosis of left ventricular outflow tract caused by severe kyphosis. Int J Cardiol. 2012;155:e47-48

135. Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Ako J, Momomura S. Complications of temporary vena cava filter placement. Journal of cardiology. 2012;60:306-309

136. Yamasaki M, Tsujino I, Lima-Filho MO, Ako J, Shimohama T, Hasegawa T, Sakurai R, Sudhir K, Stone GW, Waseda K, Honda Y, Fitzgerald PJ. Comparison of vascular response to the everolimus-eluting stent versus the paclitaxel-eluting stent: Intravascular ultrasound results from the spirit iii trial. EuroIntervention. 2012;8:724-731

137. Arao K, Ako J, Momomura S. Transient mid-ventricular ballooning: Insights from (123)i-metaiodobenzylguanidine (mibg) scintigraphy. Int J Cardiol. 2013;164:e15-16

138. Arao K, Fujiwara T, Sakakura K, Wada H, Sugawara Y, Suga C, Ako J, Ishikawa SE, Momomura S. Hyponatremia as a predictor for worsening heart failure in patients receiving cardiac resynchronization therapy. Circ J. 2013;77:116-122

139. Fujiwara T, Ako J, Sugawara Y, Momomura S. Late-gadolinium enhancement in cardiac sarcoidosis. European heart journal. 2013;34:2411

140. Hasumi E, Iwata H, Kohro T, Manabe I, Kinugawa K, Morisaki N, Ando J, Sawaki D, Takahashi M, Fujita H, Yamashita H, Ako J, Hirata Y, Komuro I, Nagai R. Diagnostic implication of change in b-type natriuretic peptide (bnp) for prediction of subsequent target lesion revascularization following silorimus-eluting stent deployment. Int J Cardiol. 2013

141. Hayashi T, Fukamizu S, Hojo R, Komiyama K, Tanabe Y, Tejima T, Nishizaki M, Hiraoka M, Ako J, Momomura SI, Sakurada H. Fragmented qrs predicts cardiovascular death of patients with structural heart disease and inducible ventricular tachyarrhythmia. Circ J. 2013

142. Hayashi T, Fukamizu S, Hojo R, Komiyama K, Tanabe Y, Tejima T, Nishizaki M, Hiraoka M, Ako J, Momomura SI, Sakurada H. Prevalence and electrophysiological characteristics of typical atrial flutter in patients with atrial fibrillation and chronic obstructive pulmonary disease. Europace : . 2013

143. Hayashi T, Fukamizu S, Hojo R, Komiyama K, Tanabe Y, Tejima T, Soejima K, Nishizaki M, Hiraoka M, Ako J, Momomura SI, Sakurada H. Prophylactic catheter ablation for induced monomorphic ventricular tachycardia in patients with implantable cardioverter defibrillators as primary prevention. Europace : 2013

144. Ishida K, Wada H, Sakakura K, Kubo N, Ikeda N, Sugawara Y, Ako J, Momomura S. Long-term follow-up on cardiac function following fulminant myocarditis requiring percutaneous extracorporeal cardiopulmonary support. Heart and vessels. 2013;28:86-90

145. Jinnouchi H, Sakakura K, Matsuda J, Wakabayashi Y, Wada H, Momomura S, Ako J. Recurrent spontaneous coronary artery dissection observed with multiple imaging modalities. International heart journal. 2013;54:181-183

146. Jinnouchi H, Sakakura K, Wada H, Arao K, Kubo N, Sugawara Y, Funayama H, Momomura SI, Ako J. Transient no reflow following primary percutaneous coronary intervention. Heart and vessels. 2013

147. Jinnouchi H, Sakakura K, Wada H, Kubo N, Sugawara Y, Funayama H, Ako J, Momomura S. Clinical features of myocardial infarction in young japanese patients. International heart journal. 2013;54:123-128

148. Nakagawa T, Wada H, Sakakura K, Yamada Y, Ishida K, Ibe T, Ikeda N, Sugawara Y, Ako J, Momomura SI. Clinical features of infective endocarditis: Comparison between the 1990s and 2000s. Journal of cardiology. 2013

149. Sakakura K, Wada H, Taniguchi Y, Mori M, Momomura S, Ako J. Intravascular ultrasound-guided coronary stenting without contrast medium for the treatment of catheter-induced aortocoronary dissection. Cardiovascular intervention and therapeutics. 2013;28:71-75

150. Sasai H, Sakakura K, Yuri K, Wada H, Arao K, Funayama H, Sugawara Y, Yamaguchi A, Adachi H, Momomura S, Ako J. Fractional flow reserve for a mild stenosis on the donor artery to chronic total occlusion. Cardiovascular intervention and therapeutics. 2013;28:193-196

151. Taniguchi Y, Sakakura K, Wada H, Sugawara Y, Funayama H, Kubo N, Momomura S, Ako J. Contrast induced exacerbation of renal dysfunction in the advanced chronic kidney disease. Cardiovascular intervention and therapeutics. 2013;28:157-161

152. Ueba H, Shiomi M, Brines M, Yamin M, Kobayashi T, Ako J, Momomura S, Cerami A, Kawakami M. Suppression of coronary atherosclerosis by helix b surface peptide, a nonerythropoietic, tissue-protective compound derived from erythropoietin. Mol Med. 2013;19:195-202

153. Wada H, Yasu T, Sakakura K, Hayakawa Y, Ishida T, Kobayashi N, Kubo N, Ako J, Momomura SI. Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction. Heart and vessels. 2013

154. ArakaAko Jwa M, Yamaguchi A, Sakakura K, Okamura H, Ako J, Momomura S and Adachi H. SYNTAX-justified trend toward restricting coronary artery bypass grafting to more serious cases. General thoracic and cardiovascular surgery. 2014;62:364-9.

155. Arao K, Fujiwara T, Taniguchi Y, Jinnouchi H, Sasai H, Matsumoto M, Funayama H, Ako J and Momomura SI. Implications of pentraxin 3 levels in patients with acute aortic dissection. Heart and vessels. 2014.

156. Arao K, Kuribara A, Jinnouchi H, Matsumoto M, Fujiwara T, Kinoshita N, Kakehashi A, Ako J and Momomura S. Transient retinopathy in acute aortic dissection. Ophthalmology. 2014;121:2261-7.

157. Fujiwara T, Yoshida M, Nakamura T, Sakakura K, Wada H, Arao K, Katayama T, Funayama H, Sugawara Y, Mitsuhashi T, Kakei M, Momomura SI and Ako J. Dipeptidyl peptidase-4 inhibitors are associated with improved left ventricular diastolic function after acute myocardial infarction in diabetic patients. Heart and vessels. 2014.

158. Fujiwara T, Yoshida M, Yamada H, Tsukui T, Nakamura T, Sakakura K, Wada H, Arao K, Katayama T, Funayama H, Sugawara Y, Mitsuhashi T, Kakei M, Momomura SI and Ako J. Lower 1,5-anhydroglucitol is associated with denovo coronary artery disease in patients at high cardiovascular risk. Heart and vessels. 2014.

159. Hashikata T, Tojo T, Namba S, Kitasato L, Hashimoto T, Kameda R, Shimohama T, Yamaoka-Tojo M and Ako J. Neointimal coverage of zotarolimus-eluting stent at 1, 2, and 3 months' follow-up: an optical coherence tomography study. Heart and vessels. 2014.

160. Hashikata T, Tojo T, Namba S, Kitasato L, Hashimoto T, Kameda R, Shimohama T, Yamaoka-Tojo M, Takada F and Ako J. Deficiency of creatine kinase in a ST-segment elevation myocardial infarction patient with Kartagener syndrome. Int J Cardiol. 2014;182C:31-33.

161. Ikeda Y, Inomata T, Fujita T, Iida Y, Nabeta T, Naruke T, Koitabashi T, Takeuchi I, Kitamura T, Miyaji K and Ako J. Morphological changes in mitochondria during mechanical unloading observed on electron microscopy: a case report of a bridge to complete recovery in a patient with idiopathic dilated cardiomyopathy. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2014.

162. Jinnouchi H, Sakakura K, Wada H, Arao K, Kubo N, Sugawara Y, Funayama H, Momomura S and Ako J. Transient no reflow following primary percutaneous coronary intervention. Heart and vessels. 2014;29:429-36.

163. Jinnouchi H, Sakakura K, Wada H, Ishida K, Arao K, Kubo N, Sugawara Y, Funayama H, Ako J and Momomura S. Effect of chronic statin treatment on vascular remodeling determined by intravascular ultrasound in patients with acute myocardial infarction. Am J Cardiol. 2014;113:924-9.

164. Kishihara J, Niwano S, Niwano H, Aoyama Y, Satoh A, Oikawa J, Kiryu M, Fukaya H, Masaki Y, Tamaki H, Izumi T and Ako J. Effect of carvedilol on atrial remodeling in canine model of atrial fibrillation. Cardiovascular diagnosis and therapy. 2014;4:28-35.

165. Kitasato L, Yamaoka-Tojo M, Hashikata T, Ishii S, Kameda R, Shimohama T, Tojo T and Ako J. Factor Xa in mouse fibroblasts may induce fibrosis more than thrombin. International heart journal. 2014;55:357-61.

166. Kurokawa S, Niwano S, Niwano H, Murakami M, Ishikawa S, Masaki Y, Tamaki H, Toda T, Noda Y, Shimizu T, Izumi T and Ako J. Cardiomyocyte-derived mitochondrial superoxide causes myocardial electrical remodeling by downregulating potassium channels and related molecules. Circ J. 2014;78:1950-9.

167. Morino Y, Ako J, Kobayashi M and Nakamura M. Japanese postmarketing surveillance of clopidogrel for patients with non-ST-segment-elevation acute coronary syndrome indicated for percutaneous coronary intervention (J-PLACE NSTE-ACS). Cardiovascular intervention and therapeutics. 2014;29:123-33.

168. Nabeta T, Itatani K, Miyaji K and Ako J. Vortex flow energy loss reflects therapeutic effect in dilated cardiomyopathy. European heart journal. 2014.

169. Nakagawa T, Wada H, Sakakura K, Yamada Y, Ishida K, Ibe T, Ikeda N, Sugawara Y, Ako J and Momomura S. Clinical features of infective endocarditis: comparison between the 1990s and 2000s. Journal of cardiology. 2014;63:145-8.

170. Shimohama T and Ako J. Intrastent Thrombus. Circ J. 2014.

171. Taniguchi Y, Funayama H, Matsuda J, Fujita K, Nakagawa T, Nakamura T, Umemoto T, Mitsuhashi T, Ako J and Momomura S. Super-selective intracoronary injection of Rho-kinase inhibitor relieves refractory coronary vasospasms: A case report. Int J Cardiol. 2014;176:270-1.

172. Wada H, Yasu T, Sakakura K, Hayakawa Y, Ishida T, Kobayashi N, Kubo N, Ako J and Momomura S. Contrast echocardiography for the diagnosis of left ventricular thrombus in anterior myocardial infarction. Heart and vessels. 2014;29:308-12.

173. Yamamoto K, Wada H, Sakakura K, Ikeda N, Yamada Y, Katayama T, Sugawara Y, Mitsuhashi T, Ako J and Momomura S. Cardiovascular and bleeding risk of non-cardiac surgery in patients on antiplatelet therapy. Journal of cardiology. 2014;64:334-8.

174. Yoshizawa T, Niwano S, Niwano H, Igarashi T, Fujiishi T, Ishizue N, Oikawa J, Satoh A, Kurokawa S, Hatakeyama Y, Fukaya H and Ako J. Prediction of new onset atrial fibrillation through P wave analysis in 12 lead ECG. International heart journal. 2014;55:422-7.

175. Hashikata T, Tojo T, Namba S, Kitasato L, Hashimoto T, Kameda R, Shimohama T, Yamaoka-Tojo M, Takada F and Ako J. Deficiency of creatine kinase in a ST-segment elevation myocardial infarction patient with Kartagener syndrome. Int J Cardiol. 2015;182:31-3.

176. Hashikata T, Yamaoka-Tojo M, Namba S, Kitasato L, Kameda R, Murakami M, Niwano H, Shimohama T, Tojo T and Ako J. Rivaroxaban Inhibits Angiotensin II-Induced Activation in Cultured Mouse Cardiac Fibroblasts Through the Modulation of NF-kappaB Pathway. International heart journal. 2015;56:544-50.

177. Ikeda Y, Inomata T, Fujita T, Iida Y, Nabeta T, Naruke T, Koitabashi T, Takeuchi I, Kitamura T, Miyaji K and Ako J. Morphological changes in mitochondria during mechanical unloading observed on electron microscopy: a case report of a bridge to complete recovery in a patient with idiopathic dilated cardiomyopathy. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2015;24:128-31.

178. Ikeda Y, Inomata T, Iida Y, Iwamoto-Ishida M, Nabeta T, Ishii S, Sato T, Yanagisawa T, Mizutani T, Naruke T, Koitabashi T, Takeuchi I, Nishii M and Ako J. Time course of left ventricular reverse remodeling in response to pharmacotherapy: clinical implication for heart failure prognosis in patients with idiopathic dilated cardiomyopathy. Heart and vessels. 2015.

179. Kamiya K, Masuda T, Tanaka S, Hamazaki N, Matsue Y, Mezzani A, Matsuzawa R, Nozaki K, Maekawa E, Noda C, Yamaoka-Tojo M, Arai Y, Matsunaga A, Izumi T and Ako J. Quadriceps Strength as a Predictor of Mortality in Coronary Artery Disease. Am J Med. 2015;128:1212-9.

180. Kitasato L, Shimohama T, Ikeda Y, Namba S, Hashikata T, Kameda R, Sato N, Takeuchi I, Yamaoka-Tojo M, Tojo T and Ako J. Clinical outcomes of chronic kidney disease patients treated with everolimus-eluting stents (EES) and paclitaxel-eluting stents (PES). Biomed Pharmacother. 2015;72:6-10.

181. Komatsu T, Morita M, Miyaji F, Inomata T, Ako J and Atsuda K. Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients. J Pharm Health Care Sci. 2015;1:25.

182. Nabeta T, Itatani K, Miyaji K and Ako J. Vortex flow energy loss reflects therapeutic effect in dilated cardiomyopathy. European heart journal. 2015;36:637.

183. Namba S, Yamaoka-Tojo M, Hashikata T, Ikeda Y, Kitasato L, Hashimoto T, Shimohama T, Tojo T, Takahira N, Masuda T and Ako J. Long-term warfarin therapy and biomarkers for osteoporosis and atherosclerosis. BBA Clin. 2015;4:76-80.

184. Nishio R, Shinke T, Morino Y, Tanabe K, Furuya J, Takizawa K, Ako J, Kozuma K, Hibi K, Ishii H, Hirohata A, Otsuka Y, Otake H, Takaya T and Hirata K. Early Phase Arterial Reaction Following Drug-Eluting and Bare-Metal Stent Implantation in Patients With ST-Segment Elevation Myocardial Infarction. International heart journal. 2015;56:389-94.

185. Seguchi M, Wada H, Sakakura K, Nakagawa T, Ibe T, Ikeda N, Sugawara Y, Ako J and Momomura S. Circadian variation of acute aortic dissection. International heart journal. 2015;56:324-8.

186. Shimohama T and Ako J. Inside Out, Outside in - Vasa Vasorum and Coronary Spasm. Circ J. 2015;79:1693-4.

187. Shimohama T and Ako J. Intrastent thrombus - what you see is what you get? Circ J. 2015;79:41-2.

188. Takeuchi I, Fujita H, Yanagisawa T, Sato N, Mizutani T, Hattori J, Asakuma S, Yamaya T, Inagaki T, Kataoka Y, Ohe K, Ako J and Asari Y. Impact of Doctor Car with Mobile Cloud ECG in reducing door-to- balloon time of Japanese ST-elevation myocardial infarction patients. International heart journal. 2015;56:170-3.

189. Tanno J, Nakano S, Kasai T, Ako J, Nakamura S, Senbonmatsu T and Nishimura S. Increase in Ultrasonic Intensity of Blood Speckle across Moderate Coronary Artery Stenosis Is an Independent Predictor of Functional Coronary Artery Stenosis Measured by Fractional Flow Reserve: Pilot Study. PloS one. 2015;10:e0116727.
190. Wakabayashi Y, Funayama H, Ugata Y, Taniguchi Y, Hoshino H, Ako J and Momomura S. Low eicosapentaenoic acid to arachidonic acid ratio is associated with thin-cap fibroatheroma determined by optical coherence tomography. Journal of cardiology. 2015;66:482-8.

191. Wakabayashi Y, Wada H, Sakakura K, Yamamoto K, Mitsuhashi T, Ako J and Momomura S. Major adverse cardiac and bleeding events associated with non-cardiac surgery in coronary artery disease patients with or without prior percutaneous coronary intervention. Journal of cardiology. 2015;66:341-6.

192. Wakabayashi Y, Wada H, Sakakura K, Yamamoto K, Mitsuhashi T, Ako J and Momomura SI. Major adverse cardiac and bleeding events associated with non-cardiac surgery in coronary artery disease patients with or without prior percutaneous coronary intervention. Journal of cardiology. 2015.
193. Ako J and Hashimoto T. [Antiplatelet medicine]. Nihon rinsho Japanese journal of clinical medicine. 2016;74 Suppl 4 Pt 1:538-43.
194. Ako J, Morino Y, Okuizumi K, Usami M and Nakamura M. Japanese postmarketing surveillance of clopidogrel in patients with non-ST-segment elevation acute coronary syndrome, stable angina, old myocardial infarction, and ST-segment elevation myocardial infarction after percutaneous coronary intervention in a real-life setting: the final report (J-PLACE Final). Cardiovascular intervention and therapeutics. 2016;31:101-13.

195. Fujiishi T, Niwano S, Murakami M, Nakamura H, Igarashi T, Ishizue N, Oikawa J, Kishihara J, Fukaya H, Niwano H and Ako J. Efficacy and Limitations of Tachycardia Detection Interval Guided Reprogramming for Reduction of Inappropriate Shock in Implantable Cardioverter-Defibrillator Patients. International heart journal. 2016;57:304-9.

196. Fujiwara T, Yoshida M, Akashi N, Yamada H, Tsukui T, Nakamura T, Sakakura K, Wada H, Arao K, Katayama T, Umemoto T, Funayama H, Sugawara Y, Mitsuhashi T, Kakei M, Momomura S and Ako J. Lower 1,5-anhydroglucitol is associated with adverse clinical events after percutaneous coronary intervention. Heart and vessels. 2016;31:855-62.

197. Fukaya H and Ako J. Triple Antithrombotic Therapy - Always One Too Many? Circ J. 2016;80:316-7.

198. Fukaya H, Niwano S, Oikawa J, Nishinarita R, Horiguchi A, Nakamura H, Fujiishi T, Igarashi T, Ishizue N, Yoshizawa T, Satoh A, Kishihara J, Murakami M and Ako J. Safety of low-dose dabigatran in patients with atrial fibrillation and mild renal insufficiency. Journal of cardiology. 2016.

199. Hara H, Niwano S, Ito H, Karakawa M and Ako J. Evaluation of R-wave offset in the left chest leads for estimating the left ventricular activation delay: An evaluation based on coronary sinus electrograms and the 12-lead electrocardiogram. J Electrocardiol. 2016;49:148-53.

200. Hashikata T, Tojo T, Namba S, Kitasato L, Hashimoto T, Kameda R, Shimohama T, Yamaoka-Tojo M and Ako J. Neointimal coverage of zotarolimus-eluting stent at 1, 2, and 3 months' follow-up: an optical coherence tomography study. Heart and vessels. 2016;31:206-11.

201. Hashikata T, Yamaoka-Tojo M, Kakizaki R, Nemoto T, Fujiyoshi K, Namba S, Kitasato L, Hashimoto T, Ishii S, Kameda R, Shimohama T, Tojo T and Ako J. Ezetimibe enhances and stabilizes anticoagulant effect of warfarin. Heart and vessels. 2016.

202. Hashikata T, Yamaoka-Tojo M, Kakizaki R, Nemoto T, Fujiyoshi K, Namba S, Kitasato L, Hashimoto T, Kameda R, Maekawa E, Shimohama T, Tojo T and Ako J. Erratum to: Teneligliptin improves left ventricular diastolic function and endothelial function in patients with diabetes. Heart and vessels. 2016;31:1311-1312.

203. Hashikata T, Yamaoka-Tojo M, Kakizaki R, Nemoto T, Fujiyoshi K, Namba S, Kitasato L, Hashimoto T, Kameda R, Maekawa E, Shimohama T, Tojo T and Ako J. Teneligliptin improves left ventricular diastolic function and endothelial function in patients with diabetes. Heart and vessels. 2016;31:1303-10.
204. Hashimoto T and Ako J. [Antiplatelet therapy after the drug-eluting stent placement]. Nihon rinsho Japanese journal of clinical medicine. 2016;74 Suppl 4 Pt 1:384-8.
205. Ibe T, Wada H, Sakakura K, Ikeda N, Yamada Y, Sugawara Y, Mitsuhashi T, Ako J, Fujita H and Momomura S. Pulmonary hypertension due to left heart disease: The prognostic implications of diastolic pulmonary vascular pressure gradient. Journal of cardiology. 2016;67:555-9.

206. Igarashi T, Niwano S, Fukaya H, Yoshizawa T, Nakamura H, Fujiishi T, Ishizue N, Oikawa J, Kishihara J, Murakami M, Niwano H and Ako J. Discrimination of Paroxysmal and Persistent Atrial Fibrillation in Patients With New-Onset Atrial Fibrillation. International heart journal. 2016;57:573-9.

207. Ikeda Y, Inomata T, Fujita T, Iida Y, Kaida T, Nabeta T, Ishii S, Maekawa E, Yanagisawa T, Mizutani T, Naruke T, Koitabashi T, Takeuchi I and Ako J. Higher hemoglobin A1c levels are associated with impaired left ventricular diastolic function and higher incidence of adverse cardiac events in patients with nonischemic dilated cardiomyopathy. Heart and vessels. 2016.

208. Ikeda Y, Inomata T, Fujita T, Iida Y, Nabeta T, Ishii S, Maekawa E, Yanagisawa T, Mizutani T, Naruke T, Koitabashi T, Takeuchi I and Ako J. Cardiac fibrosis detected by magnetic resonance imaging on predicting time course diversity of left ventricular reverse remodeling in patients with idiopathic dilated cardiomyopathy. Heart and vessels. 2016.

209. Ikeda Y, Inomata T, Iida Y, Iwamoto-Ishida M, Nabeta T, Ishii S, Sato T, Yanagisawa T, Mizutani T, Naruke T, Koitabashi T, Takeuchi I, Nishii M and Ako J. Time course of left ventricular reverse remodeling in response to pharmacotherapy: clinical implication for heart failure prognosis in patients with idiopathic dilated cardiomyopathy. Heart and vessels. 2016;31:545-54.

210. Ikeda Y, Inomata T, Nishinarita R, Oikawa J, Kishihara J, Koitabashi T, Wada T, Takeuchi I and Ako J. Giant cell myocarditis associated with multiple autoimmune disorders following highly active antiretroviral therapy for human immunodeficiency virus type 1 infection. Int J Cardiol. 2016;206:79-81.

211. Ishii S, Inomata T, Fujita T, Iida Y, Ikeda Y, Nabeta T, Yanagisawa T, Naruke T, Mizutani T, Koitabashi T, Takeuchi I and Ako J. Clinical significance of endomyocardial biopsy in conjunction with cardiac magnetic resonance imaging to predict left ventricular reverse remodeling in idiopathic dilated cardiomyopathy. Heart and vessels. 2016.

212. Ishizue N, Niwano S, Saito M, Fukaya H, Nakamura H, Igarashi T, Fujiishi T, Yoshizawa T, Oikawa J, Satoh A, Kishihara J, Murakami M, Niwano H, Miyaoka H and Ako J. Polytherapy with sodium channel-blocking antiepileptic drugs is associated with arrhythmogenic ST-T abnormality in patients with epilepsy. Seizure. 2016;40:81-7.

213. Kakizaki R, Nabeta T, Ishii S, Koitabashi T, Itatani K, Inomata T and Ako J. Cardiac resynchronization therapy reduces left ventricular energy loss. Int J Cardiol. 2016;221:546-8.

214. Kakizaki R, Nabeta T, Mizutani T, Koitabashi T and Ako J. Tumor Plop Sound. Circ J. 2016.

215. Kamiya K, Masuda T, Matsue Y, Inomata T, Hamazaki N, Matsuzawa R, Tanaka S, Nozaki K, Maekawa E, Noda C, Yamaoka-Tojo M, Matsunaga A, Izumi T and Ako J. Complementary Role of Arm Circumference to Body Mass Index in Risk Stratification in Heart Failure. JACC Heart Fail. 2016;4:265-73.

216. Kamiya K, Satoh A, Niwano S, Tanaka S, Miida K, Hamazaki N, Maekawa E, Matsuzawa R, Nozaki K, Masuda T and Ako J. Safety of neuromuscular electrical stimulation in patients implanted with cardioverter defibrillators. J Electrocardiol. 2016;49:99-101.

217. Kishihara J, Niwano S, Nakamura H, Igarashi T, Ishizue N, Fujiishi T, Oikawa J, Murakami M, Fukaya H and Ako J. An appropriate shock of the wearable cardioverter-defibrillator in an outpatient setting. J Arrhythm. 2016;32:67-9.

218. Komatsu T, Inomata T, Watanabe I, Kobayashi M, Kokubun H, Ako J and Atsuda K. Population pharmacokinetic analysis and dosing regimen optimization of penicillin G in patients with infective endocarditis. J Pharm Health Care Sci. 2016;2:9.

219. Minami Y, Meguro K, Shimohama T, Yanagisawa T, Kakizaki R, Tojo T and Ako J. Successful Retrieval of Entrapped Balloon With Optical Coherence Tomography Guidance. Jacc. 2016;9:2070-2071.

220. Nabeta T, Inomata T, Iida Y, Ikeda Y, Iwamoto-Ishida M, Ishii S, Naruke T, Mizutani T, Shinagawa H, Koitabashi T, Takeuchi I and Ako J. Prognostic significance of beta-blocker up-titration in conjunction with cardiac resynchronization therapy in heart failure management. Heart and vessels. 2016;31:1109-16.

221. Noguchi M, Yamada Y, Sakakura K, Katayama T, Momomura S and Ako J. Coronary thrombus aspiration revealed tumorous embolism of myxofibrosarcoma from the left atrium. Cardiovascular intervention and therapeutics. 2016;31:75-8.

222. Oyama J, Tanaka A, Sato Y, Tomiyama H, Sata M, Ishizu T, Taguchi I, Kuroyanagi T, Teragawa H, Ishizaka N, Kanzaki Y, Ohishi M, Eguchi K, Higashi Y, Yamada H, Maemura K, Ako J, Bando YK, Ueda S, Inoue T, Murohara T, Node K and Investigators PS. Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat: the PRIZE study. Cardiovasc Diabetol. 2016;15:87.

223. Sato K, Abe K, Kosaka Y, Ohuchi T, Okamoto H, Ako J and Kumabe T. [A Case of Cardiac Arrest Caused by Coronary Spasm Related to Induction of General Anesthesia before Carotid Endarterectomy]. No Shinkei Geka. 2016;44:591-8.

224. Sato K, Fujiyoshi K, Hoshi K, Noda C, Yamaoka-Tojo M, Ako J and Kumabe T. Low Stroke Rate of Carotid Stenosis Under the Guideline-Oriented Medical Treatment Compared With Surgical Treatment. International heart journal. 2016;57:80-6.

225. Satoh A, Niwano S, Niwano H, Kishihara J, Aoyama Y, Oikawa J, Fukaya H, Tamaki H and Ako J. Aliskiren suppresses atrial electrical and structural remodeling in a canine model of atrial fibrillation. Heart and vessels. 2016.

226. Tanaka A, Inoue T, Kitakaze M, Oyama J, Sata M, Taguchi I, Shimizu W, Watada H, Tomiyama H, Ako J, Sakata Y, Anzai T, Uematsu M, Suzuki M, Eguchi K, Yamashina A, Saito Y, Sato Y, Ueda S, Murohara T and Node K. Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial. Cardiovasc Diabetol. 2016;15:57.

228. Tanaka S, Kamiya K, Masuda T, Hamazaki N, Matsuzawa R, Nozaki K, Maekawa E, Noda C, Yamaoka-Tojo M, Matsunaga A and Ako J. Low ankle brachial index is associated with the magnitude of impaired walking endurance in patients with heart failure. Int J Cardiol. 2016;224:400-405.

229. Tsutsui H, Momomura S, Yamashina A, Ogawa H, Shimokawa H, Kihara Y, Saito Y, Hagiwara N, Ito H, Ako J, Inomata T, Tanaka T, Kawasaki Y and study i. Heart Rate Control With If Inhibitor, Ivabradine, in Japanese Patients With Chronic Heart Failure- A Randomized, Double-Blind, Placebo-Controlled Phase II Study. Circ J. 2016;80:668-76.

230. Waseda K, Ako J, Kume T, Fitzgerald PJ and Honda Y. Characteristics of Late-Acquired Incomplete Stent Apposition: A Comparison With First-Generation and Second-Generation Drug-Eluting Stents. J Invasive Cardiol. 2016;28:323-9.

231. Yonezu K, Funayama H, Katayama T, Yamaguchi A, Ako J and Momomura S. Ruptured saphenous vein graft pseudoaneurysm successfully treated with covered stents. Cardiovascular intervention and therapeutics. 2016;31:161-3.

2, Textbook Chapters, invited articles and reviews

1. Ako J, Hassan A, Honda Y, Fitzgerald PJ. Available transcatheter mitral valve repair techniques: CS method. In: Hijazi Z, Bonhoeffer P, Feldman TE, et al., eds. Transcatheter Valve Repair. 1 ed. London: Taylor & Francis Books Ltd; 2005:286-294.

2. Yamasaki M, Ako J, Honda Y, Fitzgerald PJ. Intravascular ultrasound. In: Bernhard Meier, Editor. Current Best Practice in Interventional Cardiology. Wiley-Blackwell; 2010: 206-211.

3. Ako J, Waseda K. Intravascular Ultrasound In: Principles of Vascular and Intravascular Ultrasound. Saunders;2011.

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