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ADRB2 gene polymorphism and emphysema heterogeneity can modulate bronchodilator response in patients with emphysema. Pulm Pharmacol Ther. Feb;48:80-87, 2018.
Nojiri M, Mizuno S, Nishiki K, Kato R, Nakagawa K, Oikawa T, Iguchi M, Osanai, K, Ishizaki T, Toga H.
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p53 signaling pathway polymorphisms associated with emphysematous changes in COPD patients. Chest, 152:58-69, 2017.
Mizuno S, Ishizaki T, Kadowaki M, Akai M, Shiozaki K, Iguchi M, Oikawa T, Nakagawa K, Osanai K, Toga H, Gomez-Arroyo J, Kraskauskas D, Cool CD, Bogaard HJ, Voelkel NF.
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Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease.・Respir Res. 17:139, 2016.
Kato R, Mizuno S, Kadowaki M, Shiozaki K, Akai M, Nakagawa K, Oikawa T, Iguchi M, Osanai K, Ishizaki T, Voelkel NF, Toga H.
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Endogenous Asymmetric Dimethylarginine Pathway in High Altitude Adapted Yaks. Biomed Res Int, 196904, 2015.
Mizuno S, Ishizaki T, Toga H, Sakai, A, Isakova J, Taalaibekova E, Baiserkeev Z, Kojonazarov B, Aldashev A.
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Blunted activation of Rho-kinase in the yak’s pulmonary circulation. Biomed Res Int, 2015:720250, 2015.
Ishizaki T, Mizuno S, Sakai A, Matsukawa S, Kojonazarov B, Zamirbek B, Umeda Y, Morikawa M, Ishizuka T, Aldashev A.
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Iloprost Reverses Established Fibrosis In Experimental Right Ventricular Failure. Eur Respir J, 45(2):449-62, 2015.
Gomez-Arroyo J,Sakagami M, Syed AA, Farkas L,Tassell BV, Kraskauskas1 D, Mizuno S, Abbate A, Bogaard HJ, Byron PR, Voelkel NF.
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Adenovector mediated gene transfer of lysophosphatidylcholine acyltransferase 1 attenuates oleic acid-induced acute lung injury in rats. Crit Care Med., 42(11):e716-24, 2014.
Zhou M, Osanai K, Kobayashi M, Oikawa T, Nakagawa K, Mizuno S, Toga H.
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A three microphone acoustic reflection technique using transmitted acoustic waves in the airway. J Appl Physiol., 5;115(8):1119-25, 2013.
Fujimoto Y, Huang J, Fukunaga T, Kato R, Higashino M, Shinomiya S, Kitadate S, Takahara Y, Yamaya A, Saito M, Kobayashi M, Kojima K, Oikawa T, Nakagawa K, Tsuchihara K, Iguchi M, Takahashi M, Mizuno S, Osanai K, Toga H.
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Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate. PLoS One. 8(1):e53927, 2013.
Yasuo M, Mizuno S, Allegood J, Kraskauskas D, Bogaard HJ, Spiegel S, Voelkel NF.
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Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy due to Pulmonary Arterial Hypertension・Circ Heart Fail. 6(1):136-44, 2013.
Gomez-Arroyo J, Mizuno S, Szczepanek K, Tassell BV, Natarajan1 R, Remedios CGD, Drake1 J, Farkas L, Kraskauskas1 D, Bigbee J, Wijesinghe D, Chalfant C, Abbate A, Lesnefsky EJ, Bogaard HJ and Voelkel NF.
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Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. Eur Respir J. 41(1):104-14, 2013.
Al Husseini A, Bagnato G, Farkas L, Gomez-Arroyo J, Farkas D, Mizuno S, Kraskauskas D, Abbate A, Van Tassel Pharm D B, Voelkel NF, Bogaard HJ.
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Severe Pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. Am J Respir Cell Mol Biol. 47(5):679-87, 2012.
Mizuno S, Farkas L, Alhussaini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF.
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MicroRNA-199a-5p is associated with hypoxia inducible factor-1α expression in the lung from COPD patients. Chest, 142(3):663-672, 2012.
Mizuno S, Bogaard HJ, Gomez-Arroyo J, Alhussaini A, Kraskauskas D, Cool CD, Voelkel NF.
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Copper-dependence of angioproliferation in pulmonary arterial hypertension in rats and humans. Am J Respir Cell Mol Biol. 46(5):582-91,2012.
Bogaard HJ, Mizuno S, Guignabert C, Al Hussaini AA, Farkas D, Ruiter G, Kraskauskas D, Fadel E, Allegood JC, Humbert M, Vonk Noordegraaf A, Spiegel S, Farkas L, Voelkel NF.
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Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation. PLoS ONE, 7(1):e30678, 2012.
Mizuno S, Yasuo M, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Farkas D, Farkas L, Voelkel NF.
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Molecular Signature of a Right Heart Failure Program in Chronic Severe Pulmonary Hypertension. Am J Respir Cell Mol Biol. 45(6):1239-47, 2011.
Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, Dumur CI, Fawcett P, Voelkel NF, Natarajan R.
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p53 gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. Am J Physiol Lung Cell Mol Physiol. ・300(5):L753-61. 2011.
Mizuno S, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Voelkel NF, Ishizaki T.
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Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats. Am J Respir Crit Care Med. 15;183(10):1402-10. 2011.
Bogaard HJ, Mizuno S, Al Hussaini AA, Toldo S, Abbate A, Kraskauskas D, Kasper M, Natarajan R, Voelkel NF.
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Inhibition of histone deacetylase causes emphysema. Am J Physiol Lung Cell Mol Physiol. 300(3):L402-13, 2011.
Mizuno S, Yasuo M, Bogaard HJ, Kraskauskas D, Natarajan R, Voelkel NF.
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・Hypoxia inducible factor-1 {alpha} in human emphysema lung tissue.・Eur Respir J.・37(4):775-83, 2011.
Yasuo M, Mizuno S, Kraskauskas D, Bogaard HJ, Natarajan R, Cool CD, Zamora M, Voelkel NF.
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・Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats.・Am J Respir Crit Care Med.・182(5):652-60, 2010.
Bogaard HJ, Natarajan R, Mizuno S, Abbate A, Chang PJ, Chau VQ, Hoke NN, Kraskauskas D, Kasper M, Salloum FN, Voelkel NF.
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・Hypoxia regulates human lung fibroblast proliferation via p53-dependent and -independent pathways.・Respir Res.・6;10:・17・2009.
Mizuno S, Bogaard HJ, Voelkel NF, Umeda Y, Kadowaki M, Ameshima S, Miyamori I, Ishizaki T.
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・Multi-arterial infusion chemotherapy for non-small cell lung carcinoma--significance of detecting feeding arteries and tumor staining.・Lung Cancer.・61(2)・227-34・2008.
Nakanishi M, Demura Y, Umeda Y, Mizuno S, Ameshima S, Chiba Y, Ishizaki T.
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・Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27kip1.・Respir Res.・1;8:・77・2007.
Kadowaki M, Mizuno S, Demura Y, Ameshima S, Miyamori I, Ishizaki T.
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・Hypoxia-induced proliferation of human pulmonary arterial smooth musclecells (PASMC) is involved in the suppression of cyclin-dependent kinase inhibitors, p21, p27 and p53.・Problems of High Altitude Medicine Biology.・10・87-99・2007.
T.Ishizaki, S.Mizuno, M.Kadowaki, D.Uesaka, Y.Umeda, M.Morikawa, M.Nakanishi, Y.Demura, S.Ameshima, S.Matsukawa.
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・Changes in HRCT findings in patients with respiratory bronchiolitis-associated interstitial lung disease after smoking cessation.・Eur Respir J.・29(3)・453-61・2007.
Nakanishi M, Demura Y, Mizuno S, Ameshima S, Chiba Y, Miyamori I, Itoh H, Kitaichi M, Ishizaki T.
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・Reappraisal of clindamycin IV monotherapy for treatment of mild-to-moderate aspiration pneumonia in elderly patients.・Chest.・127(4)・1276-82・2005.
Kadowaki M, Demura Y, Mizuno S, Uesaka D, Ameshima S, Miyamori I, Ishizaki T.
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・p42/44 Mitogen-activated protein kinase regulated by p53 and nitric oxide in human pulmonary arterial smooth muscle cells.・Am J Respir Cell Mol Biol.・31(2)・184-92・2004.
Mizuno S, Kadowaki M, Demura Y, Ameshima S, Miyamori I, Ishizaki T.
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18F-FDG accumulation with PET for differentiation between benign and malignant lesions in the thorax. J Nucl Med. 2003 Apr;44(4):540-8.
Demura Y, Tsuchida T, Ishizaki T, Mizuno S, Totani Y, Ameshima S, Miyamori I, Sasaki M, Yonekura Y.
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・Alkalosis stimulates endothelial nitric oxide synthase in cultured human pulmonary arterial endothelial cells.・Am J Physiol Lung Cell Mol Physiol.・283(1)・L113-9・2002.
Mizuno S, Demura Y, Ameshima S, Okamura S, Miyamori I, Ishizaki T.
