内野 美樹 うちの みき 先生

来歴等

略歴

1995年 学芸大学附属高校 卒業
2001年 山梨医科大学 医学部 卒業
2001年 慶應義塾大学 眼科学教室 入局
2012年 米国マサチューセッツ眼科耳鼻科病院 研究員
2015年 米国Harvard大学 公衆衛生学修士 取得
2016年 慶應義塾大学眼科学教室 特任講師
2020年 ケイシン五反田アイクリニック 院長

論文

• TFOS DEWS II Epidemiology Report. Ocul Surf. 2017 Jul;15(3):334-365.

  Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, Na KS, Schaumberg D, Uchino M, Vehof J, Viso E, Vitale S, Jones L.

• Current Prevalence of Myopia and Association of Myopia With Environmental Factors Among Schoolchildren in Japan. JAMA Ophthalmol. 2019 Aug 15;137(11):1233-9.

  Yotsukura E, Torii H, Inokuchi M, Tokumura M, Uchino M, Nakamura K, Hyodo M, Mori K, Jiang X, Ikeda SI, Kondo S, Negishi K, Kurihara T, Tsubota K.

• What Have We Learned From the Osaka Study? Cornea. 2018 Nov;37 Suppl 1:S62-S66.

  Uchino M, Uchino Y, Kawashima M, Yokoi N, Tsubota K.

• Characteristics and Risk Factors Associated With Diagnosed and Undiagnosed Symptomatic Dry Eye Using a Smartphone Application. JAMA Ophthalmol. 2019 Nov 27;138(1):58-68.

  Inomata T, Iwagami M, Nakamura M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A.

• Risk Factors for Severe Dry Eye Disease: Crowdsourced Research Using DryEyeRhythm. Ophthalmology. 2019 May;126(5):766-768.

  Inomata T, Nakamura M, Iwagami M, Shiang T, Yoshimura Y, Fujimoto K, Okumura Y, Eguchi A, Iwata N, Miura M, Hori S, Hiratsuka Y, Uchino M, Tsubota K, Dana R, Murakami A.

• High Myopia and Its Associated Factors in JPHC-NEXT Eye Study: A Cross-Sectional Observational Study. J Clin Med. 2019 Oct 25;8(11):1788.

  Mori K, Kurihara T, Uchino M, Torii H, Kawashima M, Sasaki M, Ozawa Y, Yamagishi K, Iso H, Sawada N, Tsugane S, Yuki K, Tsubota K.

• Quality of life measures and health utility values among dry eye subgroups. Health Qual Life Outcomes. 2018 Aug 31;16(1):170.

  Shigeyasu C, Yamada M, Kawashima M, Suwaki K, Uchino M, Hiratsuka Y, Yokoi N, Tsubota K; DECS-J study group.

• What We Know About the Epidemiology of Dry Eye Disease in Japan. Invest Ophthalmol Vis Sci. 2018 Nov 1;59(14):DES1-DES6.

  Uchino M.

• Evaluation of a paper-based visual acuity questionnaire. Clin Ophthalmol. 2017 Jun 27;11:1213-1217.

  Uchino M, Kawashima M, Kaido M, Suwaki K, Uchino Y, Kawachi I, Negishi K, Tsubota K.

• Gender differences in adolescent dry eye disease: a health problem in girls. Int J Ophthalmol. 2018 Feb 18;11(2):301-307.

  Ayaki M, Kawashima M, Uchino M, Tsubota K, Negishi K.

• Association between tear film break up time and blink interval in visual display terminal users. Int J Ophthalmol. 2018 Oct 18;11(10):1691-1697.

  Uchino M, Kawashima M, Uchino Y, Tsubota K, Yokoi N.

• Influence of Meibomian Gland Dysfunction and Friction-Related Disease on the Severity of Dry Eye. Ophthalmology. 2018 Aug;125(8):1181-1188.

  Vu CHV, Kawashima M, Yamada M, Suwaki K, Uchino M, Shigeyasu C, Hiratsuka Y, Yokoi N, Tsubota K; Dry Eye Cross-Sectional Study in Japan Study Group.

• Long-Term Topical Diquafosol Tetrasodium Treatment of Dry Eye Disease Caused by Chronic Graft-Versus-Host Disease: A Retrospective Study. Eye Contact Lens. 2018 Nov;44 Suppl 2:S215-S220.

  Yamane M, Ogawa Y, Fukui M, Kamoi M, Uchino M, Saijo-Ban Y, Kozuki N, Mukai S, Mori T, Okamoto S, Tsubota K.

• The evaluation of dry eye mobile apps for screening of dry eye disease and educational tear event in Japan. Ocul Surf. 2018 Oct;16(4):430-435.

  Uchino M, Kawashima M, Uchino Y, Suzuki N, Mitamura H, Mizuno M, Hori Y, Yokoi N, Tsubota K.

• Value of considering psychological strengths in patients with eye pain. Am J Ophthalmol Case Rep. 2018 Oct 11;12:91-92. doi: 10.1016/j.ajoc.2018.10.003. eCollection 2018 Dec.PMID: 30364663 Free PMC article.

  Matsuguma S, Kawashima M, Uchino M, Tsubota K.

• Lack of social support and social trust as potential risk factors for dry eye disease: JPHC-NEXT study. Ocul Surf. 2019 Apr;17(2):278-284.

  Viet Vu CH, Uchino M, Kawashima M, Yuki K, Tsubota K, Nishi A, German CA, Sakata K, Tanno K, Iso H, Yamagishi K, Yasuda N, Saito I, Kato T, Arima K, Tomita Y, Shimazu T, Yamaji T, Goto A, Inoue M, Iwasaki M, Sawada N, Tsugane S; JPHC-NEXT Study Group.

• Intake of vegetables and fruits and the risk of cataract incidence in a Japanese population: the Japan Public Health Center-based Prospective Study. J Epidemiol. 2019 Dec 14.

  Adachi S, Sawada N, Yuki K, Uchino M, Iwasaki M, Tsubota K, Tsugane S.

• Possible association between subtypes of dry eye disease and seasonal variation. Clin Ophthalmol. 2017 Sep 30;11:1769-1775.

  Ayaki M, Kawashima M, Uchino M, Tsubota K, Negishi K.

• In Vivo Confocal Microscopy Evaluation of Ocular Surface with Graft-Versus-Host Disease-Related Dry Eye Disease. Sci Rep. 2017 Sep 6;7(1):10720.

  He J, Ogawa Y, Mukai S, Saijo-Ban Y, Kamoi M, Uchino M, Yamane M, Ozawa N, Fukui M, Mori T, Okamoto S, Tsubota K.

• A Clinic-based Survey of Clinical Characteristics and Practice Pattern of Dry Eye in Japan. Adv Ther. 2017 Mar;34(3):732-743.

  Kawashima M, Yamada M, Suwaki K, Shigeyasu C, Uchino M, Hiratsuka Y, Yokoi N, Tsubota K; DECS-J Study Group.

• Long-term Natural History of Dry Eye Disease from the Patient's Perspective. Ophthalmology. 2016 Feb;123(2):425-433.

  Lienert JP, Tarko L, Uchino M, Christen WG, Schaumberg DA.

• The association of sleep quality with dry eye disease: the Osaka study. Clin Ophthalmol. 2016 Jun 1;10:1015-21.

  Kawashima M, Uchino M, Yokoi N, Uchino Y, Dogru M, Komuro A, Sonomura Y, Kato H, Kinoshita S, Tsubota K.

• Randomized, Multicenter, Double-Blind Study of the Safety and Efficacy of 1%D-3-Hydroxybutyrate eye drops for Dry Eye Disease. Sci Rep. 2016 Feb 11;6:20855.

  Kawakita T, Uchino M, Fukagawa K, Yoshino K, Shimazaki S, Toda I, Tanaka M, Arai H, Sakatani K, Hata S, Okano T, Tsubota K.

• Analysis of the association between the severity of ocular and systemic pain. Ocul Surf. 2019 Jul;17(3):434-439.

  Yamanishi R, Uchino M, Kawashima M, Dogru M, Matsuguma S, Tsubota K.

• Importance of tear film instability in dry eye disease in office workers using visual display terminals: the Osaka study. Am J Ophthalmol. 2015 Apr;159(4):748-54.

  Yokoi N, Uchino M, Uchino Y, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Tsubota K, Kinoshita S.

• One-year clinical evaluation of 0.4% ripasudil (K-115) in patients with open-angle glaucoma and ocular hypertension. Acta Ophthalmol. 2016 Feb;94(1):e26-34. doi: 10.1111/aos.12829. Epub 2015 Sep 4.

  Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Fukushima A, Suganami H, Araie M; K-115 Clinical Study Group.

• Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers. Sci Rep. 2016 Jun 14;6:27699.

  Uchino Y, Uchino M, Yokoi N, Dogru M, Kawashima M, Komuro A, Sonomura Y, Kato H, Argüeso P, Kinoshita S, Tsubota K.

• The antiaging approach for the treatment of dry eye. Cornea. 2012 Nov;31 Suppl 1:S3-8.

  Tsubota K, Kawashima M, Inaba T, Dogru M, Matsumoto Y, Ishida R, Kaido M, Kojima T, Uchino M, Uchino Y, Ogawa Y, Nakamura S, Higuchi A, Shinmura K, Watanabe M, Kawakita T.

• The Association between Dry Eye Disease and Physical Activity as well as Sedentary Behavior: Results from the Osaka Study. J Ophthalmol. 2014;2014:943786. doi: 10.1155/2014/943786.

  Kawashima M, Uchino M, Yokoi N, Uchino Y, Dogru M, Komuro A, Sonomura Y, Kato H, Nishiwaki Y, Kinoshita S, Tsubota K.

• Screening of dry eye disease in visual display terminal workers during occupational health examinations: The Moriguchi study. J Occup Health. 2015;57(3):253-8. doi: 10.1539/joh.14-0243-OA. Epub 2015 Mar 6.PMID: 25752660

  Kawashima M, Yamatsuji M, Yokoi N, Fukui M, Ichihashi Y, Kato H, Nishida M, Uchino M, Kinoshita S, Tsubota K.

著書

• Column for Public Questions: Mobile site “General medicine and drug”. 2011-2013 Question from the public: What is going on with my eye?

• Answers: 1) “Tear dropping with wind.” 2011.4

• 2) “I have a floater. Is it an insect?” 2011.5

• 3) “Is herpes contagious?” 2011.6

• 4) “I have hazy vision while wearing contact lenses.” 2011.7

• 5) “I cannot open my eyes in the morning.” 2011.8

• 6) “It is hard to keep my eyes open.” 2011.8

• 7) “It is too bright to keep my eyes open!” 2011.11

• 8) “The light runs through my vision.” 2011.11

• 9) “My conjunctiva is red.” 2011.12

• 10) “Dry eye. How can I prevent it?” 2012.2

• 11) “Can age related macular degeneration be inherited?” 2012.3

• 12) “My eyes are bleeding!” 2012.4

• 13) “What is uveitis?” 2012.6

• 14) “Is it OK to purchase color contact lenses on the internet?” 2012.7

• 15) “ Can Lasik provide better vision?” 2012.9

• 16) “I have hazy vision.” 2012.11

• 17) “What will happen to the cornea ripped epithelium?” 2012.12

• 18) “Will I be blind from retinal pigmentary degeneration?” 2013.3

• 19) “Does a neck incline for a squint?” 2013.5

• 20) “Do I need an operation for my trichiasis?” 2013.6

• 21) “I have been diagnosed with glaucoma.” 2013.8

• 22) “Some mosaic is in front of my vision.” 2013.9

• 23) “My conjunctiva is swollen.” 2013.10

• Healthcare web “Goo” 1) “Be aware of summer eye problems!”, 2009.7

• 2) “What is discharge?”

• 3) “Do you think presbyopia is not a problem in your 40’s?” 2012.10

• Preventive Education Tool for pre-K: 2013.6-7 1) Shimajiro Eye Care Kit for 3/4 years

• “What do you do at an eye hospital?” 2) Shimajiro Eye Care Kit for 4/5 years

• “Eye and tear story.” 3) Shimajiro Eye Care Kit for 5/6 years

• “Can you keep the promise?” 1) -3) were distributed about 700,000childrens (Almost 20% of the children aged 3-6 years old)

その他

• 【DVD】The myopia prevention DVD.2013.9-10 Distributed in about 700,000 children (Almost 20% of children aged 3-6 years old )

• 【DVD】Educational tool for kindergarten teachers: “The supporting book for children’s eye” 2013.4-6

• 【受賞】2020年　日本角膜学会奨励賞受賞

• 【テレビ出演】“What is Presbyopia”: Nippon Television Network Corporation in September, 2007

• 【テレビ出演】“Patients Increase in Ophthalmology for Dry Eye Disease”, Japan Broadcasting Corporation in February, 2011

• 【テレビ出演】“Dry Eye Disease”, Nippon Television Network Corporation. December, 2011

• 【テレビ出演】“How to Prevent Dry Eye Disease” Nippon Television Network Corporation. January, 2012

• 【テレビ出演】“Dry Eye Disease with Short Break up Time”, Japan Broadcasting Corporation. February, 2012

• 【テレビ出演】“How to Find Dry Eye Disease”, Fuji Television. March, 2012

• 【テレビ出演】“Sulfuric Acid Eye Drop Affect the Cornea”, Japan Broadcasting Corporation. February, 2012

• 【新聞】“How to do Cataract Surgery with Low Endothelial Corneal?”, Asahi newspaper company, 2006

• 【新聞】“Eye Care in Summer”, The Nikkei, 2007

• 【新聞】“Prevalence of Dry Eye Disease in Rural Area”, Medical Tribune in May, 2011