須田 智 すだ さとし 先生

来歴等

略歴

1999年 日本医科大学医学部 卒業
1999年 日本医科大学 第二内科 入局
2011年 日本医科大学大学院 博士課程修了（医学博士）
2012年 テキサス大学ヒューストン校 神経内科 ポストドクトラルフェロー
2014年 日本医科大学 神経・脳血管内科 病院講師
2017年 日本医科大学 脳神経内科 講師
2021年 日本医科大学 脳神経内科 准教授
2023年 埼玉医科大学国際医療センター 脳神経内科・脳卒中内科 診療部長・教授
2025年 日本医科大学大学院医学研究科 神経内科学分野 大学院教授

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論文

• 1. LOOK Study Investigators. Atrial fibrillation detection in cryptogenic stroke and a prediction score using imaging examination. J Neurol Sci. 2025 Jun 15;473:123528. doi: 10.1016/j.jns.2025.123528. Epub 2025 May 6. PMID: 40359774.

  Katano T, Suda S, Morimoto M, Tsuboi Y, Sonoda T, Sonoda K, Koga M, Ihara M, Iguchi Y, Murakami H, Yazawa Y, Kimura K.

• 2. Effectiveness and Limitations of Intravenous rt-PA Therapy in Patients with Mild Cerebral Infarction. J Atheroscler Thromb. 2025 Jun 1;32(6):661-669. doi: 10.5551/jat.RV22034. Epub 2025 Mar 26. PMID: 40139842; PMCID: PMC12140849.

  Deguchi I, Takahashi S, Suda S.

• 3. Cardioembolic Stroke: Past Advancements, Current Challenges, and Future Directions. Int J Mol Sci. 2024 May 26;25(11):5777. doi: 10.3390/ijms25115777. PMID: 38891965; PMCID: PMC11171744.

  Kato Y, Tsutsui K, Nakano S, Hayashi T, Suda S.

• 4. PASTA Investigators. High brain natriuretic peptide level is associated with severe stroke in patients taking oral anticoagulants: A sub-analysis of the PASTA registry study. J Neurol Sci. 2024 Mar 15;458:122935. doi: 10.1016/j.jns.2024.122935. Epub 2024 Feb 15. PMID: 38368640.

  Suda S, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Fujimoto S, Kono Y, Kimura K.

• 5. Prevalence and outcome of pre-onset frailty in patients with acute stroke. Top Stroke Rehabil. 2024 Jul;31(5):493-500. doi: 10.1080/10749357.2023.2291898. Epub 2023 Dec 18. PMID: 38108292.

  Iwasawa T, Aoyagi Y, Suda S, Ishiyama D, Toi K, Ohashi M, Kimura K.

• 6. PASTA Investigators. Resumption of oral anticoagulation in patients with non- valvular atrial fibrillation after intracerebral hemorrhage: A sub-analysis of the PASTA registry study. J Neurol Sci. 2023 Oct 15;453:120810. doi: 10.1016/j.jns.2023.120810. Epub 2023 Sep 14. PMID: 37742350.

  Suda S, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Fujimoto S, Kono Y, Kimura K.

• 7. Regular pulse checks for patients with non-cardioembolic stroke in rehabilitation hospitals to improve recognition and detection of atrial fibrillation (the ESCORT study): protocol for a prospective multicenter observational study. Front Neurol. 2023 Aug 16;14:1247020. doi: 10.3389/fneur.2023.1247020. PMID: 37662047; PMCID: PMC10468993.

  Katano T, Suda S, Ohta T, Miyagami M, Kodaira Y, Konaka C, Nagashima M, Kimura K.

• 8. iPSC-derived mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by inhibiting inflammatory signaling and oxidative stress. Mol Ther Methods Clin Dev. 2023 Jul 15;30:333-349. doi: 10.1016/j.omtm.2023.07.005. PMID: 37637385; PMCID: PMC10448333.

  Arakawa M, Sakamoto Y, Miyagawa Y, Nito C, Takahashi S, Nitahara-Kasahara Y, Suda S, Yamazaki Y, Sakai M, Kimura K, Okada T.

• 9. PASTA Investigators. Safety of recanalization therapy in patients with acute ischemic stroke on direct oral anticoagulants: A sub-analysis of PASTA registry study. J Neurol Sci. 2023 May 15;448:120639. doi: 10.1016/j.jns.2023.120639. Epub 2023 Mar 28. PMID: 37030185.

  Suda S, Abe A, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Fujimoto S, Kono Y, Kimura K.

• 10. PASTA study group. Vitamin K antagonists but not non-vitamin K antagonists in addition on antiplatelet therapy should be associated with increase of hematoma volume and mortality in patients with intracerebral hemorrhage: A sub-analysis of PASTA registry study. J Neurol Sci. 2023 May 15;448:120643. doi: 10.1016/j.jns.2023.120643. Epub 2023 Apr 1. PMID: 37028263.

  Nomura K, Suda S, Abe A, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Fujimoto S, Kimura K.

• 11. J- REPAIR trial group. Randomised placebo-controlled multicentre trial to evaluate the efficacy and safety of JTR-161, allogeneic human dental pulp stem cells, in patients with Acute Ischaemic stRoke (J-REPAIR). BMJ Open. 2022 May 24;12(5):e054269. doi: 10.1136/bmjopen-2021-054269. PMID: 35613802; PMCID: PMC9125710.

  Suda S, Nito C, Ihara M, Iguchi Y, Urabe T, Matsumaru Y, Sakai N, Kimura K.

• 12. Dental-Pulp Stem Cells as a Therapeutic Strategy for Ischemic Stroke. Biomedicines. 2022 Mar 22;10(4):737. doi: 10.3390/biomedicines10040737. PMID: 35453487; PMCID: PMC9032844.

  Nito C, Suda S, Nitahara-Kasahara Y, Okada T, Kimura K.

• 13. PASTA study group. Sustained atrial fibrillation is related to a higher severity of stroke in patients taking direct oral anticoagulants. J Neurol Sci. 2022 Mar 15;434:120172. doi: 10.1016/j.jns.2022.120172. Epub 2022 Jan 31. PMID: 35176560.

  Hayashi T, Suda S, Abe A, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Fujimoto S, Kimura K.

• 14. PASTA Investigators. Prior direct oral anticoagulant dosage and outcomes in patients with acute ischemic stroke and non-valvular atrial fibrillation: A sub-analysis of PASTA registry study. J Neurol Sci. 2022 Mar 15;434:120163. doi: 10.1016/j.jns.2022.120163. Epub 2022 Jan 26. PMID: 35121210.

  Mashiko T, Fujimoto S, Suda S, Abe A, Iguchi Y, Yagita Y, Kanzawa T, Okubo S, Todo K, Yamazaki M, Nakajima N, Kondo K, Inoue T, Iwanaga T, Terasawa Y, Shibazaki K, Kimura K.

• 15. Fluid-Attenuated Inversion Recovery May Serve As a Tissue Clock in Patients Treated With Endovascular Thrombectomy. Stroke. 2021 Jul;52(7):2232-2240. doi: 10.1161/STROKEAHA.120.033374. Epub 2021 May 7. PMID: 33957776.

  Aoki J, Sakamoto Y, Suzuki K, Nishi Y, Kutsuna A, Takei Y, Sawada K, Kanamaru T, Abe A, Katano T, Takeshi Y, Nakagami T, Numao S, Kimura R, Suda S, Nishiyama Y, Kimura K.

• 16. The Effect of Aging and Small-Vessel Disease Burden on Hematoma Location in Patients with Acute Intracerebral Hemorrhage. Cerebrovasc Dis. 2021;50(5):526-534. doi: 10.1159/000515411. Epub 2021 Apr 23. PMID: 33895747.

  Sakamoto Y, Sato T, Nito C, Nishiyama Y, Suda S, Matsumoto N, Aoki J, Saito T, Suzuki K, Katano T, Kimura K.

• 17. Pre-stroke cognitive impairment in acute ischemic stroke patients predicts poor functional outcome after mechanical thrombectomy. Neurol Sci. 2021 Nov;42(11):4629-4635. doi: 10.1007/s10072-021-05158-6. Epub 2021 Mar 5. PMID: 33666769.

  Kanamaru T, Suda S, Muraga K, Ishiwata A, Aoki J, Suzuki K, Sakamoto Y, Katano T, Nishimura T, Nishiyama Y, Kimura K.

• 18. Recent Advances in Cell-Based Therapies for Ischemic Stroke. Int J Mol Sci. 2020 Sep 14;21(18):6718. doi: 10.3390/ijms21186718. PMID: 32937754; PMCID: PMC7555943.

  Suda S, Nito C, Yokobori S, Sakamoto Y, Nakajima M, Sowa K, Obinata H, Sasaki K, Savitz SI, Kimura K.

• 19. Reducing door-to-reperfusion time in acute stroke endovascular therapy using magnetic resonance imaging as a screening modality. J Neurointerv Surg. 2020 Nov;12(11):1080-1084. doi: 10.1136/neurintsurg-2019-015625. Epub 2020 Feb 12. PMID: 32051322; PMCID: PMC7569364.

  Sakamoto Y, Suzuki K, Abe A, Aoki J, Kanamaru T, Takayama Y, Katano T, Kutsuna A, Suda S, Nishiyama Y, Nito C, Kimura K.

• 20. Therapeutic potential of AMPA receptor antagonist perampanel against cerebral ischemia: beyond epileptic disorder. Neural Regen Res. 2019 Sep;14(9):1525-1526. doi: 10.4103/1673-5374.255964. PMID: 31089049; PMCID: PMC6557096.

  Suda S, Kimura K.

• 21. Feasibility of Human Neural Stem Cell Transplantation for the Treatment of Acute Subdural Hematoma in a Rat Model: A Pilot Study. Front Neurol. 2019 Feb 12;10:82. doi: 10.3389/fneur.2019.00082. PMID: 30809187; PMCID: PMC6379455.

  Yokobori S, Sasaki K, Kanaya T, Igarashi Y, Nakae R, Onda H, Masuno T, Suda S, Sowa K, Nakajima M, Spurlock MS, Onn Chieng L, Hazel TG, Johe K, Gajavelli S, Fuse A, Bullock MR, Yokota H.

• 22. Transplantation of human dental pulp stem cells ameliorates brain damage following acute cerebral ischemia. Biomed Pharmacother. 2018 Dec;108:1005-1014. doi: 10.1016/j.biopha.2018.09.084. Epub 2018 Sep 27. PMID: 30372800.

  Nito C, Sowa K, Nakajima M, Sakamoto Y, Suda S, Nishiyama Y, Nakamura-Takahashi A, Nitahara-Kasahara Y, Ueda M, Okada T, Kimura K.

• 23. Emergent Large Vessel Occlusion Screen Is an Ideal Prehospital Scale to Avoid Missing Endovascular Therapy in Acute Stroke. Stroke. 2018 Sep;49(9):2096-2101. doi: 10.1161/STROKEAHA.118.022107. PMID: 30354974.

  Suzuki K, Nakajima N, Kunimoto K, Hatake S, Sakamoto Y, Hokama H, Nomura K, Hayashi T, Aoki J, Suda S, Nishiyama Y, Kimura K.

• 24. Anticoagulants, Reperfusion Therapy, and Outcomes in Ischemic Stroke Patients With Non-Valvular Atrial Fibrillation - A Single-Center, 6-Year Experience of 546 Consecutive Patients. Circ J. 2018 Sep 25;82(10):2647-2654. doi: 10.1253/circj.CJ-18-0561. Epub 2018 Aug 30. PMID: 30158346.

  Suda S, Sakamoto Y, Okubo S, Aoki J, Shimoyama T, Kanamaru T, Suzuki K, Kutsuna A, Matsumoto N, Nito C, Nishiyama Y, Mishina M, Kimura K.

• 25. Impact of Dental Pulp Stem Cells Overexpressing Hepatocyte Growth Factor after Cerebral Ischemia/Reperfusion in Rats. Mol Ther Methods Clin Dev. 2018 Aug 4;10:281-290. doi: 10.1016/j.omtm.2018.07.009. PMID: 30151417; PMCID: PMC6108066.

  Sowa K, Nito C, Nakajima M, Suda S, Nishiyama Y, Sakamoto Y, Nitahara-Kasahara Y, Nakamura-Takahashi A, Ueda M, Kimura K, Okada T.

• 26. AMPA Receptor Antagonist Perampanel Ameliorates Post-Stroke Functional and Cognitive Impairments. Neuroscience. 2018 Aug 21;386:256-264. doi: 10.1016/j.neuroscience.2018.06.043. Epub 2018 Jul 5. PMID: 29981363.

  Nakajima M, Suda S, Sowa K, Sakamoto Y, Nito C, Nishiyama Y, Aoki J, Ueda M, Yokobori S, Yamada M, Yokota H, Okada T, Kimura K.

• 27. Working Group for Guidelines on Development of Cell-Based Products for the Treatment of Cerebral Infarction. Accelerating Cell Therapy for Stroke in Japan: Regulatory Framework and Guidelines on Development of Cell-Based Products. Stroke. 2018 Apr;49(4):e145-e152. doi: 10.1161/STROKEAHA.117.019216. Epub 2018 Mar 16. PMID: 29581346.

  Houkin K, Shichinohe H, Abe K, Arato T, Dezawa M, Honmou O, Horie N, Katayama Y, Kudo K, Kuroda S, Matsuyama T, Miyai I, Nagata I, Niizuma K, Sakushima K, Sasaki M, Sato N, Sawanobori K, Suda S, Taguchi A, Tominaga T, Yamamoto H, Yamashita T, Yoshimine T.

• 28. Stroke-associated infection independently predicts 3-month poor functional outcome and mortality. J Neurol. 2018 Feb;265(2):370-375. doi: 10.1007/s00415-017-8714-6. Epub 2017 Dec 16. PMID: 29249057.

  Suda S, Aoki J, Shimoyama T, Suzuki K, Sakamoto Y, Katano T, Okubo S, Nito C, Nishiyama Y, Mishina M, Kimura K.

• 29. Prevalence and clinical characteristics of cortical superficial siderosis in patients with acute stroke. J Neurol. 2017 Dec;264(12):2413-2419. doi: 10.1007/s00415-017-8646-1. Epub 2017 Oct 23. PMID: 29063241.

  Suda S, Shimoyama T, Suzuki S, Ouchi T, Arakawa M, Aoki J, Suzuki K, Sakamoto Y, Okubo S, Nishiyama Y, Nito C, Mishina M, Kimura K.

• 30. Mesenchymal Stem Cells Overexpressing Interleukin-10 Promote Neuroprotection in Experimental Acute Ischemic Stroke. Mol Ther Methods Clin Dev. 2017 Jun 23;6:102-111. doi: 10.1016/j.omtm.2017.06.005. PMID: 28725658; PMCID: PMC5502709.

  Nakajima M, Nito C, Sowa K, Suda S, Nishiyama Y, Nakamura-Takahashi A, Nitahara-Kasahara Y, Imagawa K, Hirato T, Ueda M, Kimura K, Okada T.

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著書

• 1. 須田 智 （2024） 8-A抗凝固薬 9脳卒中とてんかん. （木村和美 編） 日本医大式 脳卒中ポケットマニュアル第2版, 医歯薬出版株式会社 （東京） 244-250, 275-279.

• 2. 須田 智 （2018） 脳出血モデル. 脳卒中病態学のススメ （下畑享良 編） 南山堂 （東京） 225-230.

• 3. Suda S (2017) Chaper1: Bone Marrow-Derived Mononuclear Cells. Cell Therapy against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials. Houkin K, Abe K, Kuroda S (editors) Springer (Germany), 3-14.

• 4. 脳卒中治療Controversy （担当：分担執筆, 範囲：入院時，塞栓症が強く疑われる患者の抗血栓薬はどうするか？）　外医学社 2023年3月 （ISBN: 978449832896)

• 5. 「週刊 医学の歩み 発展する脳卒中診療の最前線」 澤田 和貴, 須田智, 木村和美 （担当：分担執筆, 範囲：抗凝固療法の最近の動向） 歯薬出版株式会社 2022年3月

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