藤城 弘樹 ふじしろ ひろしげ 先生

来歴等

略歴

2000年 愛媛大学医学部 卒業
2006年 名古屋大学大学院医学系研究科 卒業 博士（医学）取得
2006年 メイヨークリニック 神経病理 リサーチフェロー
2009年 順天堂東京江東高齢者医療センター 精神医学 准教授
2014年 名古屋大学大学院医学系研究科睡眠医学 講師
2018年 かわさき記念病院 精神科 診療部長
2020年 かわさき記念病院 精神科 副院長
2022年 名古屋大学大学院医学系研究科精神医療学 特任准教授
2025年 名古屋大学大学院医学系研究科精神医療学 特任教授

論文

• 1. Electroconvulsive therapy for dementia with Lewy bodies: A systematic review and Japanese multicenter survey Asian J Psychiatr. 2025; 103:104314

  *Fujishiro H, Iwata-Endo K, Kobayashi R, Morikawa F, Ikeda M.

• 2. Validation of the neuropathological criteria of the fourth Consortium for dementia with Lewy bodies to autopsy cases in psychiatric hospitals. Psychiatry Clin Neurosci 2025; 79(6):344-355

  Takeda K, *Fujishiro H, Torii Y, Sekiguchi H, Arafuka S, Habuchi C, Miwa A, Ozaki N, Yoshida M, Iritani S, Iwasaki Y, Ikeda M.

• 3. Neuropatholgical substrate of incident dementia in older patients with schizophrenia: A clinicopathological study Psychiatry Clin Neurosci 2024;78:29-40.

  Arafuka S, *Fujishiro H, Torii Y, Sekiguchi H, Habuchi C, Miwa A, Yoshida M, Iritani S, Iwasaki Y, Ikeda M, Ozaki N.

• 4. Clinical presentations and diagnostic application of proposed biomarkers in psychiatric-onset prodromal dementia with Lewy bodies.Psychogeriatrics. 2024;24(4):1004-1022.

  Kobayashi R, Iwata-Endo K, *Fujishiro H.

• 5. Temporal trajectories of proposed biomarkers in psychiatric-onset prodromal dementia with Lewy bodies: a case report. Psychogeriatrics 23:196-200, 2023

  *Fujishiro H, Arafuka S, Ogasawara K, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N.

• 6. Towards an understanding of the pathological basis of senile depression and incident dementia: implications for treatment. Psychiatry Clin Neurosci 76(12):620-632, 2022.

  Kawakami I, Iga JI, Takahashi S, Lin Y-T, *Fujishiro H.

• 7. Early diagnosis of prodromal dementia with Lewy bodies using clinical history of probable REM sleep behavior disorder and cardiac 123I-MIBG scintigraphy in memory clinics. Psychogeriatrics 21:288-295, 2021

  *Fujishiro H, Ota K, Yamagata, Ito T, Hieda S, Suga H, Fukui T, Nagahama Y.

• 8. When does cerebral β-amyloid deposition begin in Lewy body dementia? Neurol Clin Neurosci 8: 362-371, 2020

  *Fujishiro H, Kosaka K.

• 9. Research criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology 94: 1-13, 2020

  McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, Kantarci K, Muscio C, O’Brien JT, Postuma RB, Aarsland D, Ballard C, Bonanni L, Donaghy P, Emre M, Galvin JE, Galasko D, Goldman JG, Gomperts SN, Honig LS, Ikeda M, Leverenz JB, Lewis SJB, Marder KS, Masellis M, Salmon DP, Taylor JP, Tsuang DW, Walker Z, Tiraboschi P; the prodromal DLB Dagnostic Study Group.

• 10. Clinical profiles of late-onset psychiatric patients exhibiting incidental REM sleep without atonia. J Neural Transm (Vienna). 126(8): 1095-1104, 2019.

  *Fujishiro H, Okuda M, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N.

• 11. Early diagnosis of Lewy body disease in patients with late-onset psychiatric disorders using clinical history of REM sleep behavior disorder and 123I-MIBG cardiac scintigraphy. Psychiatry Clin Neurosci 72:423-434, 2018

  *Fujishiro H, Okuda M, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N.

• 12. REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series. Int J Geriatr Psychiatry 32:397-406, 2017

  *Fujishiro H, Okuda M, Iwamoto K, Miyata S, Otake H, Noda A, Iritani S, Ozaki N.

• 13. Delirium prior to dementia as a clinical phenotype of Lewy body disease: an autopsied case report. Int Psychogeriatr 29:687-689, 2017

  *Fujishiro H, Kawakami I, Oshima K, Niizato K, Iritani S.

• 14. Diagnosis and management of dementia with Lewy bodies 4th consensus report of the DLB consortium. Neurology 89(1):88-100, 2017

  McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor J-P, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche DH, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VM, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K.

• 16. Pathology and temporal onset of visual hallucinations, misperceptions and family misidentification distinguishes Dementia with Lewy bodies from Alzheimer’s disease. Parkinsonism Relat Disord 19:227-231, 2013

  Ferman TJ, Arvanitakis Z, Fujishiro H, Duara R, Parfitt F, Purdy M, Waters C, Barker W, Graff-Radford NR, Dickson DW.

• 15. Prodromal dementia with Lewy bodies. Geriatr Gerontol Int 15:817-826,2015

  *Fujishiro H, Nakamura S, Sato K, Iseki E.

• 17. Dementia with Lewy bodies: early diagnostic challenges. Psychogeriatrics 13:128-138, 2013

  *Fujishiro H, Iseki E, Nakamura S, Kasanuki K, Chiba Y, Ota K, Murayama N, Sato K.

• 18. A follow up study of non-demented patients with primary visual cortical hypometabolism: prodromal dementia with Lewy bodies. J Neurol Sci 334:48-54, 2013

  *Fujishiro H, Iseki E, Kasanuki K, Chiba Y, Ota K, Murayama N, Sato K.

• 19. Rapid eye movement disorder and subtypes in autopsy-confirmed dementia with Lewy bodies. Mov Disord 27:72-8, 2012

  Dugger BN, Boeve BF, Murray ME, Parisi JE, Fujishiro H, Dickson DW, Ferman TJ.

• 20. Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using cardiac MIBG scintigraphy. J Neurol Sci 315:115-119, 2012

  *Fujishiro H, Nakamura S, Kitazawa M, Sato K, Iseki E.

• 21. Retrospective survey of prodromal symptoms in dementia with Lewy bodies: comparison with Alzheimer’s disease. Dement Geriatr Cogn Disord 33:273-281,2012

  Chiba Y, *Fujishiro H, Iseki E, Ota K, Kasanuki K, Hirayasu Y, Sato K.

• 22. Glucose hypometabolism in primary visual cortex is commonly associated with clinical features of dementia with Lewy bodies regardless of cognitive conditions. Int J Geriatr Psychiatry 27:1138-1146, 2012

  *Fujishiro H, Iseki E, Kasanuki K, Murayama N, Ota K, Suzuki M, Sato K.

• 23. Incidental Lewy body disease: do some cases represent preclinical dementia with Lewy bodies? Neurobiol Aging 32: 857-863, 2011

  Frigerio R, Fujishiro H, Ahn TB, Josephs KA, Maraganore D, DelleDonne A, Parisi JE, Klos K, Boeve B, Dickson DW, Ahlskog JE.

• 24. Validation of the Revised DLB Clinical Consensus Criteria: RBD Improves Classification of Autopsy-Confirmed DLB. Neurology 77:875-82, 2011

  Ferman TJ, Boeve BF, Smith GE, Lin Siong-Chi, Silber MH, Pedraza O, Wszolek Z, Graff-Radford NR, Uitti R, Gerpen JV, Pao W, Knopman D, Pankratz VS, Kantarci K, Boot B, Parisi JE, Dugger BN, Fujishiro H, Petersen RC, Dickson DW.

• 25. Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia. Neurosci Lett 486:19-23,2010

  *Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N, Togo T, Katsuse O, Uchikado H, Aoki N, Kosaka K, Arai H, Sato K.

• 26. Accumulation of phosphorylated TDP-43 in brains of patients with argyrophilic grain disease. Acta Neuropathol 117:151-8, 2009

  *Fujishiro H, Uchikado H, Arai T, Hasegawa M, Akiyama H, Yokota O, Tsuchiya K, Togo T, Iseki E, Hirayasu Y.

• 27. Incidental Lewy body disease and Parkinson's disease. Arch Neurol 65:1074-80, 2008

  DelleDonne A, Klos KJ, Fujishiro H, Ahmed Z, Parisi　JE, Josephs KA, Frigerio R, Wszolek ZK, Uitti RJ, Ahlskog JE, Dickson DW.

• 28. Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson’s disease. Mov Disord 23:1085-92, 2008

  Fujishiro H, Frigerio R, Burnett M, Klos KJ, Josephs KA, DelleDonne A, Parisi JE, Ahlskog JE, Dickson DW.

• 29. Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease. Acta Neuropathol 115:437-44, 2008

  Dickson DW, Fujishiro H, Delledonne A, Menke J, Ahmed Z, Klos KJ, Josephs KA, Frigerio R, Burnett M, Parisi JE, Ahlskog JE.

• 30. Validation of the Neuropathologic Criteria of the Third Consortium for Dementia with Lewy Bodies for Prospectively Diagnosed Cases. J Neuropathol Exp Neurol 67:649-56, 2008

  Fujishiro H, Ferman TJ, Boeve BF, Smith GE, Graff-Radford NR, Uitti RJ, Wszolek ZK, Knopman DS, Petersen RC, Parisi JE, Dickson DW

その他

• 【受賞】平成20年度　日本老年精神医学会奨励賞受賞

• 【受賞】平成23年度　ノバルティス老化および老年医学賞受賞