高後 裕 先生のプロフィール

高後 裕 先生

こうご ゆたか

高後 裕 先生

国際医療福祉大学病院 消化器センター長・予防医学センター長 国際医療福祉大学医学部教授

専門分野

消化器内科

紹介

鉄・アルコールによる消化器障害からがんに至るまで幅広い知識を持ち、患者さんひとりひとりに対する正確な診断と適切な治療を可能にしている。患者さんとそのご家族、地域の人々が気軽に安心してかかれるチーム医療を目指し日々診療にあたる。

略歴

1974年 札幌医科大学医学部 卒業
1976年 アルバート・アインシュタイン医科大学 (アメリカ) (生化学教室)
1977年 タフツ大学医学部(アメリカ)(生化学教室)
1978年 札幌医科大学医学部 助手 (がん研究所内科学部門)
1982年 札幌医科大学医学部 講師 (内科学第四講座)
1988年 札幌医科大学医学部 助教授 (内科学第四講座)
1994年 旭川医科大学医学部医学科臨床医学講座内科学講座(消化器・血液腫瘍制御内科学分野) 教授
2012年 旭川医科大学寄附講座消化管再生修復医学講座 教授 (兼務)
2015年 旭川医科大学名誉教授
2015年 国際医療福祉大学教授、国際医療福祉大学病院消化器センター長、予防医学センター長
2017年 国際医療福祉大学医学部教授

所属学会・資格・役職など

医学博士
日本消化器病学会 功労会員 認定指導医・消化器病専門医
日本消化器内視鏡学会 功労会員 認定指導医・消化器内視鏡専門医
日本肝臓学会 名誉会員、認定肝臓専門医 第 回大会会長 
日本血液学会 功労会員、認定指導医・血液専門医
日本内科学会 功労会員、認定指導医・認定内科医
日本消化器がん検診学会 評議員、認定指導医、認定医 第 回大会会長
日本アルコール・アデイクション学会 名誉会員 
日本鉄バイオサイエンス学会 前理事長、監事 第 回学術集会会長
国際バイオ鉄学会 第2回総会会長(BioIron 2007, Kyogo)
日本癌治療学会 名誉会員 第51回総会会長 理事

受賞・著書・論文など

【受賞】
札幌医科大学医師会賞
北海道知事賞
北海道医師会賞
日本癌集学的治療財団功労者賞
【著書】
浅野茂隆、池田康夫、内山卓(編) 三輪血液病学 第3版:鉄代謝、赤血球の生成と崩壊、文光堂、2006
小川 聡(総編集)高後 裕、大竹孝明(著)内科学書 改定第8版:肝疾患:アルコール性肝障害、pp 288-291,中山書店、2013
矢崎義雄(総編集)高後 裕(著)内科学 第10版: ヘモクロマトーシス, 朝倉書店、2012
日本検査血液学会(編) 高後 裕(著) 血球に関する検査:鉄代謝、医歯薬出版、2013

原著(英文)
1: Ikuta K, Hatayama M, Addo L, Toki Y, Sasaki K, Tatsumi Y, Hattori A, Kato A,
Kato K, Hayashi H, Suzuki T, Kobune M, Tsutsui M, Gotoh A, Aota Y, Matsuura M,
Hamada Y, Tokuda T, Komatsu N, Kohgo Y. Iron overload patients with unknown
etiology from national survey in Japan. Int J Hematol. 2017 Mar;105(3):353-36

【受賞】
札幌医科大学医師会賞
北海道知事賞
北海道医師会賞
日本癌集学的治療財団功労者賞
【著書】
浅野茂隆、池田康夫、内山卓(編) 三輪血液病学 第3版:鉄代謝、赤血球の生成と崩壊、文光堂、2006
小川 聡(総編集)高後 裕、大竹孝明(著)内科学書 改定第8版:肝疾患:アルコール性肝障害、pp 288-291,中山書店、2013
矢崎義雄(総編集)高後 裕(著)内科学 第10版: ヘモクロマトーシス, 朝倉書店、2012
日本検査血液学会(編) 高後 裕(著) 血球に関する検査:鉄代謝、医歯薬出版、2013

原著(英文)
1: Ikuta K, Hatayama M, Addo L, Toki Y, Sasaki K, Tatsumi Y, Hattori A, Kato A,
Kato K, Hayashi H, Suzuki T, Kobune M, Tsutsui M, Gotoh A, Aota Y, Matsuura M,
Hamada Y, Tokuda T, Komatsu N, Kohgo Y. Iron overload patients with unknown
etiology from national survey in Japan. Int J Hematol. 2017 Mar;105(3):353-360.

2: Yamamoto M, Tanaka H, Toki Y, Hatayama M, Ito S, Addo L, Shindo M, Sasaki K,
Ikuta K, Ohtake T, Fujiya M, Torimoto Y, Kohgo Y. Iron-induced epigenetic
abnormalities of mouse bone marrow through aberrant activation of aconitase and
isocitrate dehydrogenase. Int J Hematol. 2016 Oct;104(4):491-501.

3: Hasebe T, Tanaka H, Sawada K, Nakajima S, Ohtake T, Fujiya M, Kohgo Y. Bone
morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model. J Gastroenterol. 2017 Mar;52(3):341-351.

4: Toki Y, Sasaki K, Tanaka H, Yamamoto M, Hatayama M, Ito S, Ikuta K, Shindo M,
Hasebe T, Nakajima S, Sawada K, Fujiya M, Torimoto Y, Ohtake T, Kohgo Y. A
selective splicing variant of hepcidin mRNA in hepatocellular carcinoma cell
lines. Biochem Biophys Res Commun. 2016 Aug 5;476(4):501-507.

5: Ito S, Ikuta K, Kato D, Lynda A, Shibusa K, Niizeki N, Toki Y, Hatayama M,
Yamamoto M, Shindo M, Iizuka N, Kohgo Y, Fujiya M. In vivo behavior of NTBI
revealed by automated quantification system. Int J Hematol. 2016 Aug;104(2):175-81.

6: Addo L, Ikuta K, Tanaka H, Toki Y, Hatayama M, Yamamoto M, Ito S, Shindo M,
Sasaki Y, Shimonaka Y, Fujiya M, Kohgo Y. The three isoforms of hepcidin in human
serum and their processing determined by liquid chromatography-tandem mass
spectrometry (LC-tandem MS). Int J Hematol. 2016 Jan;103(1):34-43.

7: Kohgo Y, Urabe A, Kilinç Y, Agaoglu L, Warzocha K, Miyamura K, Lim LC, Glaser
S, Wang C, Wiktor-Jedrzejczak W. Deferasirox Decreases Liver Iron Concentration
in Iron-Overloaded Patients with Myelodysplastic Syndromes, Aplastic Anemia and
Other Rare Anemias. Acta Haematol. 2015;134(4):233-42.

8: Addo L, Tanaka H, Yamamoto M, Toki Y, Ito S, Ikuta K, Sasaki K, Ohtake T,
Torimoto Y, Fujiya M, Kohgo Y. Hepatic nerve growth factor induced by iron
overload triggers defenestration in liver sinusoidal endothelial cells. Biochim
Biophys Acta. 2015 Jan;1852(1):175-83.

9: Ito S, Ikuta K, Kato D, Shibusa K, Niizeki N, Tanaka H, Addo L, Toki Y,
Hatayama M, Inamura J, Shindo M, Sasaki K, Iizuka N, Fujiya M, Torimoto Y, Kohgo
Y. Non-transferrin-bound iron assay system utilizing a conventional automated
analyzer. Clin Chim Acta. 2014 Nov 1;437:129-35.

10: Sasaki Y, Shimonaka Y, Ikuta K, Hosoki T, Sasaki K, Torimoto Y, Kanada H,
Moriguchi Y, Kohgo Y. Hepcidin production in response to iron is controlled by
monocyte-derived humoral factors. Int J Hematol. 2014 Jan;99(1):12-20.

11: Ichiki K, Ikuta K, Addo L, Tanaka H, Sasaki Y, Shimonaka Y, Sasaki K, Ito S,
Shindo M, Ohtake T, Fujiya M, Torimoto Y, Kohgo Y. Upregulation of iron
regulatory hormone hepcidin by interferon α. J Gastroenterol Hepatol. 2014
Feb;29(2):387-94.
12: Sawada K, Ohtake T, Hasebe T, Abe M, Tanaka H, Ikuta K, Suzuki Y, Fujiya M,Hasebe C, Kohgo Y. Augmented hepatic Toll-like receptors by fatty acids triggerthe pro-inflammatory state of non-alcoholic fatty liver disease in mice. Hepatol Res. 2014 Aug;44(8):920-34.
13: Yoneda M, Imajo K, Eguchi Y, Fujii H, Sumida Y, Hyogo H, Ono M, Suzuki Y,Kawaguchi T, Aoki N, Sata M, Kanemasa K, Kohgo Y, Saibara T, Chayama K, Itoh Y,Yoshikawa T, Anzai K, Fujimoto K, Okanoue T, Nakajima A; Japan Study Group of Nonalcoholic Fatty Liver Disease (JSG-NAFLD). Noninvasive scoring systems inpatients with nonalcoholic fatty liver disease with normal alanineaminotransferase levels. J Gastroenterol. 2013 Sep;48(9):1051-60.
14: Shima T, Uto H, Ueki K, Takamura T, Kohgo Y, Kawata S, Yasui K, Park H,Nakamura N, Nakatou T, Tanaka N, Umemura A, Mizuno M, Tanaka J, Okanoue T. Clinicopathological features of liver injury in patients with type 2 diabetesmellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus. J Gastroenterol. 2013Apr;48(4):515-25.
15: Goto T, Ikuta K, Inamoto Y, Kamoshita S, Yokohata E, Koyama D, Onodera K,
Seto A, Watanabe K, Imahashi N, Tsukamoto S, Ozawa Y, Sasaki K, Ito M, Kohgo Y,
Miyamura K. Hyperferritinemia after adult allogeneic hematopoietic cell
transplantation: quantification of iron burden by determining
non-transferrin-bound iron. Int J Hematol. 2013 Jan;97(1):125-34.

16: Sumida Y, Yoneda M, Hyogo H, Itoh Y, Ono M, Fujii H, Eguchi Y, Suzuki Y, AokiN, Kanemasa K, Fujita K, Chayama K, Saibara T, Kawada N, Fujimoto K, Kohgo Y,Yoshikawa T, Okanoue T; Japan Study Group of Nonalcoholic Fatty Liver Disease(JSG-NAFLD). Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population. BMC Gastroenterol. 2012 Jan 5;12:2.
17: Yoneda M, Fujii H, Sumida Y, Hyogo H, Itoh Y, Ono M, Eguchi Y, Suzuki Y, AokiN, Kanemasa K, Imajo K, Chayama K, Saibara T, Kawada N, Fujimoto K, Kohgo Y,Yoshikawa T, Okanoue T; Japan Study Group of Nonalcoholic Fatty Liver Disease.Platelet count for predicting fibrosis in nonalcoholic fatty liver disease. JGastroenterol. 2011 Nov;46(11):1300-6.
18: Sumida Y, Yoneda M, Hyogo H, Yamaguchi K, Ono M, Fujii H, Eguchi Y, Suzuki Y,Imai S, Kanemasa K, Fujita K, Chayama K, Yasui K, Saibara T, Kawada N, FujimotoK, Kohgo Y, Okanoue T; Japan Study Group of Nonalcoholic Fatty Liver Disease(JSG-NAFLD). A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fattyliver disease. J Gastroenterol. 2011 Feb;46(2):257-68.
19: Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y,
Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama
N, Takahashi T, Toyokuni S. Iron overload signature in chrysotile-induced
malignant mesothelioma. J Pathol. 2012 Nov;228(3):366-77.

20: Tanaka H, Li Z, Ikuta K, Addo L, Akutsu H, Nakamura M, Sasaki K, Ohtake T,
Fujiya M, Torimoto Y, Glass J, Kohgo Y. Iron facilitator LS081 reduces
hypoxia-inducible factor-1α protein and functions as anticancer agent in
hepatocellular carcinoma. Cancer Sci. 2012 Apr;103(4):767-74.

21: Ikuta K, Ito S, Tanaka H, Sasaki K, Torimoto Y, Fujiya M, Kohgo Y.
Interference of deferasirox with assays for serum iron and serum unsaturated iron
binding capacity during iron chelating therapy. Clin Chim Acta. 2011 Nov
20;412(23-24):2261-6.

22: Sasaki K, Ikuta K, Tanaka H, Ohtake T, Torimoto Y, Fujiya M, Kohgo Y.
Improved quantification for non-transferrin-bound iron measurement using
high-performance liquid chromatography by reducing iron contamination. Mol Med
Rep. 2011 Sep-Oct;4(5):913-8.

23: Sato K, Torimoto Y, Hosoki T, Ikuta K, Takahashi H, Yamamoto M, Ito S,
Okamura N, Ichiki K, Tanaka H, Shindo M, Hirai K, Mizukami Y, Otake T, Fujiya M,
Sasaki K, Kohgo Y. Loss of ABCB7 gene: pathogenesis of mitochondrial iron
accumulation in erythroblasts in refractory anemia with ringed sideroblast with
isodicentric (X)(q13). Int J Hematol. 2011 Mar;93(3):311-8.

24: Hosoki T, Ikuta K, Shimonaka Y, Sasaki Y, Yasuno H, Sato K, Ohtake T, Sasaki
K, Torimoto Y, Saito K, Kohgo Y. Heterogeneous expressions of hepcidin isoforms
in hepatoma-derived cells detected using simultaneous LC-MS/MS. Proteomics Clin
Appl. 2009 Nov;3(11):1256-64.

25: Ikuta K, Yersin A, Ikai A, Aisen P, Kohgo Y. Characterization of the
interaction between diferric transferrin and transferrin receptor 2 by functional
assays and atomic force microscopy. J Mol Biol. 2010 Mar 26;397(2):375-84.

26: Suzuki T, Tomonaga M, Miyazaki Y, Nakao S, Ohyashiki K, Matsumura I, Kohgo Y,
Niitsu Y, Kojima S, Ozawa K. Japanese epidemiological survey with consensus
statement on Japanese guidelines for treatment of iron overload in bone marrow
failure syndromes. Int J Hematol. 2008 Jul;88(1):30-5.

27: Kato J, Kobune M, Ohkubo S, Fujikawa K, Tanaka M, Takimoto R, Takada K,
Takahari D, Kawano Y, Kohgo Y, Niitsu Y. Iron/IRP-1-dependent regulation of mRNA
expression for transferrin receptor, DMT1 and ferritin during human erythroid
differentiation. Exp Hematol. 2007 Jun;35(6):879-87.

28: Ohtake T, Saito H, Hosoki Y, Inoue M, Miyoshi S, Suzuki Y, Fujimoto Y, Kohgo
Y. Hepcidin is down-regulated in alcohol loading. Alcohol Clin Exp Res. 2007
Jan;31(1 Suppl):S2-8.

29: Saito H, Fujimoto Y, Ohtake T, Suzuki Y, Sakurai S, Hosoki Y, Ikuta K,
Torimoto Y, Kohgo Y. Up-regulation of transferrin receptor 1 in chronic hepatitis
C: Implication in excess hepatic iron accumulation. Hepatol Res. 2005
Apr;31(4):203-10.

30: Shindo M, Torimoto Y, Saito H, Motomura W, Ikuta K, Sato K, Fujimoto Y, Kohgo
Y. Functional role of DMT1 in transferrin-independent iron uptake by human
hepatocyte and hepatocellular carcinoma cell, HLF. Hepatol Res. 2006
Jul;35(3):152-62.

31: Inamura J, Ikuta K, Jimbo J, Shindo M, Sato K, Torimoto Y, Kohgo Y.
Upregulation of hepcidin by interleukin-1beta in human hepatoma cell lines.
Hepatol Res. 2005 Nov;33(3):198-205.

32: Suzuki M, Fujimoto Y, Suzuki Y, Hosoki Y, Saito H, Nakayama K, Ohtake T,
Kohgo Y. Induction of transferrin receptor by ethanol in rat primary hepatocyte
culture. Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):98S-105S.

33: Yano M, Hayashi H, Yoshioka K, Kohgo Y, Saito H, Niitsu Y, Kato J, Iino S,
Yotsuyanagi H, Kobayashi Y, Kawamura K, Kakumu S, Kaito M, Ikoma J, Wakusawa S,
Okanoue T, Sumida Y, Kimura F, Kajiwara E, Sata M, Ogata K. A significant
reduction in serum alanine aminotransferase levels after 3-month iron reduction
therapy for chronic hepatitis C: a multicenter, prospective, randomized,
controlled trial in Japan. J Gastroenterol. 2004 Jun;39(6):570-4.
34: Suzuki M, Fujimoto Y, Suzuki Y, Hosoki Y, Saito H, Nakayama K, Ohtake T,Kohgo Y. Induction of transferrin receptor by ethanol in rat primary hepatocyteculture. Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):98S-105S.
35: Kato J, Sato Y, Inui N, Nakano Y, Takimoto R, Takada K, Kobune M, Kuroiwa G,Miyake S, Kohgo Y, Niitsu Y. Ethanol induces transforming growth factor-alpha expression in hepatocytes, leading to stimulation of collagen synthesis by hepatic stellate cells. Alcohol Clin Exp Res. 2003 Aug;27(8 Suppl):58S-63S.
36: Suzuki Y, Saito H, Suzuki M, Hosoki Y, Sakurai S, Fujimoto Y, Kohgo Y.
Up-regulation of transferrin receptor expression in hepatocytes by habitual
alcohol drinking is implicated in hepatic iron overload in alcoholic liver
disease. Alcohol Clin Exp Res. 2002 Aug;26(8 Suppl):26S-31S.

37: Kato J, Kobune M, Kohgo Y, Fujikawa K, Takimoto R, Torimoto Y, Ito Y, Bessho
M, Hotta T, Hikawa A, Fujii T, Punnonen K, Niitsu Y. Ratio of transferrin (Tf) to
Tf-receptor complex in circulation differs depending on Tf iron saturation. Clin
Chem. 2002 Jan;48(1):181-3.
38: Suzuki Y, Saito H, Suzuki M, Hosoki Y, Sakurai S, Fujimoto Y, Kohgo Y.Up-regulation of transferrin receptor expression in hepatocytes by habitual alcohol drinking is implicated in hepatic iron overload in alcoholic liver disease. Alcohol Clin Exp Res. 2002 Aug;26(8 Suppl):26S-31S.
39: Tanabe H, Yokota K, Shibata N, Satoh T, Watari J, Kohgo Y. Alcohol consumption as a major risk factor in the development of early esophageal cancer in patients with head and neck cancer. Intern Med. 2001 Aug;40(8):692-6.
40: Ohhira M, Saito H, Suzuki Y, Naraki T, Sakurai S, Ohtake T, Suzuki M, OhhiraM, Fujimoto And Y, Kohgo Y. A variant of des-gamma-carboxy prothrombin wasincreased in alcoholic liver disease without hepatocellular carcinoma. AlcoholClin Exp Res. 2001 Jun;25(6 Suppl):46S-50S.
41: Ikuta K, Fujimoto Y, Suzuki Y, Tanaka K, Saito H, Ohhira M, Sasaki K, Kohgo
Y. Overexpression of hemochromatosis protein, HFE, alters transferrin recycling
process in human hepatoma cells. Biochim Biophys Acta. 2000 Apr
17;1496(2-3):221-31.
42: Ohhira M, Ohtake T, Saito H, Ikuta K, Tanaka K, Tanabe H, Kawashima T,Fujimoto Y, Naraki T, Ono M, Kohgo Y. Increase of serum des-gamma-carboxyprothrombin in alcoholic liver disease without hepatocellular carcinoma. Alcohol Clin Exp Res. 1999 Apr;23(4 Suppl):67S-70S.
43: Tanabe H, Ohhira M, Ohtsubo T, Watari J, Yokota K, Kohgo Y. Genetic polymorphism of aldehyde dehydrogenase 2 in patients with upper aerodigestivetract cancer. Alcohol Clin Exp Res. 1999 Apr;23(4 Suppl):17S-20S.
44: Ohhira M, Ohtake T, Matsumoto A, Saito H, Ikuta K, Fujimoto Y, Ono M,Toyokuni S, Kohgo Y. Immunohistochemical detection of4-hydroxy-2-nonenal-modified-protein adducts in human alcoholic liver diseases.Alcohol Clin Exp Res. 1998 May;22(3 Suppl):145S-149S.
45: Ohhira M, Ohtake T, Matsumoto A, Saito H, Ikuta K, Fujimoto Y, Ono M,
Toyokuni S, Kohgo Y. Immunohistochemical detection of 4-hydroxy-2-nonenal-modified- protein adducts in human alcoholic liver diseases. Alcohol Clin Exp Res. 1998 May;22(3 Suppl):145S-149S.

46: Kato J, Kobune M, Kohgo Y, Sugawara N, Hisai H, Nakamura T, Sakamaki S,
Sawada N, Niitsu Y. Hepatic iron deprivation prevents spontaneous development of
fulminant hepatitis and liver cancer in Long-Evans Cinnamon rats. J Clin Invest.
1996 Aug 15;98(4):923-9.
47: Ohhira M, Fujimoto Y, Matsumoto A, Ohtake T, Ono M, Kohgo Y. Hepatocellular carcinoma associated with alcoholic liver disease: a clinicopathological study and genetic polymorphism of aldehyde dehydrogenase 2. Alcohol Clin Exp Res. 1996 Dec;20(9 Suppl):378A-382A. PubMed PMID: 8986242.
48: Inui N, Kato J, Kohgo Y, Katsuki S, Niitsu Y. Detection of activity in theconditioned medium of ethanol-treated HepG2 cells which stimulates collagensynthesis in IMR-90 cells. Alcohol Clin Exp Res. 1996 Feb;20(1 Suppl):63A-65A.
49: Katsuki S, Kato J, Nakajima M, Inui N, Sasaki K, Kohgo Y, Niitsu Y. Analysis of CA repeats in first intron of class I ADH gene in Long-Evans Cinnamon rats developing fatal intoxication after ethanol intake. Alcohol Clin Exp Res. 1996Feb;20(1 Suppl):33A-35A.
50: Numata T, Kato J, Kohgo Y, Katsuki S, Kondo H, Niitsu Y. Autoantibody against a 78 kDa membrane protein of HepG2 cell in the sera of patients with alcoholic liver diseases. J Gastroenterol. 1995 Dec;30(6):751-7.
51: Nakaya R, Kohgo Y, Mogi Y, Nakajima M, Kato J, Niitsu Y. Regulation of asialoglycoprotein receptor synthesis by inflammation-related cytokines in HepG2 cells. J Gastroenterol. 1994 Feb;29(1):24-30.
52: Nakajima M, Kato J, Kohgo Y, Takeichi N, Niitsu T. Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. Alcohol Alcohol Suppl. 1994;29(1):39-43.
53: Kobune M, Kohgo Y, Kato J, Miyazaki E, Niitsu Y. Interleukin-6 enhances
hepatic transferrin uptake and ferritin expression in rats. Hepatology. 1994
Jun;19(6):1468-75.
54: Nakajima M, Kato J, Kohgo Y, Katsuki S, Inui N, Ohya M, Takeichi N, Niitu Y. Abnormal ethanol metabolism in Long-Evans Cinnamon rats, a mutant strain developing spontaneous hepatoma. Alcohol Alcohol Suppl. 1993;1B:105-8.

55: Hirayama M, Kohgo Y, Kondo H, Shintani N, Fujikawa K, Sasaki K, Kato J,
Niitsu Y. Regulation of iron metabolism in HepG2 cells: a possible role for
cytokines in the hepatic deposition of iron. Hepatology. 1993 Oct;18(4):874-80.
PubMed PMID: 8406363.

56: Kato J, Kohgo Y, Sugawara N, Katsuki S, Shintani N, Fujikawa K, Miyazaki E,
Kobune M, Takeichi N, Niitsu Y. Abnormal hepatic iron accumulation in LEC rats.
Jpn J Cancer Res. 1993 Mar;84(3):219-22.

57: Sugawara N, Ikeda T, Sugawara C, Kohgo Y, Kato J, Takeichi N. Regional
distribution of copper, zinc and iron in the brain in Long-Evans Cinnamon (LEC)
rats with a new mutation causing hereditary hepatitis. Brain Res. 1992 Aug
21;588(2):287-90.

58: Kohgo Y, Niitsu Y, Kondo H, Kato J, Tsushima N, Sasaki K, Hirayama M, Numata
T, Nishisato T, Urushizaki I. Serum transferrin receptor as a new index of
erythropoiesis. Blood. 1987 Dec;70(6):1955-8.

59: Niitsu Y, Adachi C, Takahashi F, Goto Y, Kohgo Y, Urushizaki I, Listowsky I.
Concentration-dependent sedimentation properties of ferritin: implications for
estimation of iron contents of serum ferritins. Am J Hematol. 1985
Apr;18(4):363-71.

60: Niitsu Y, Watanabe N, Onodera Y, Goto Y, Kohgo Y, Urushizaki I. Correlations
between iron content and isoferritin profiles of normal and malignant tissues.
Gan. 1984 Aug;75(8):699-702. PubMed PMID: 6489677.

61: Kohgo Y, Yokota M, Drysdale JW. Differential turnover of rat liver
isoferritins. J Biol Chem. 1980 Jun 10;255(11):5195-200.

【総説(英文)】
1: Kohgo Y, Ikuta K, Ohtake T, Torimoto Y, Kato J. Body iron metabolism and
pathophysiology of iron overload. Int J Hematol. 2008 Jul;88(1):7-15.
2: Kohgo Y, Ohtake T, Ikuta K, Suzuki Y, Torimoto Y, Kato J. Dysregulation of systemic iron metabolism in alcoholic liver diseases. J Gastroenterol Hepatol.2008 Mar;23 Suppl 1:S78-81.
3: Kohgo Y, Ikuta K, Ohtake T, Torimoto Y, Kato J. Iron overload and cofactors with special reference to alcohol, hepatitis C virus infection and steatosis/insulin resistance. World J Gastroenterol. 2007 Sep 21;13(35):4699-706.
4: Kohgo Y, Ohtake T, Ikuta K, Suzuki Y, Hosoki Y, Saito H, Kato J. Iron accumulation in alcoholic liver diseases. Alcohol Clin Exp Res. 2005 Nov;29(11Suppl):189S-93S.
5: Kohgo Y, Torimoto Y, Kato J. Transferrin receptor in tissue and serum:
updated clinical significance of soluble receptor. Int J Hematol. 76:213-8, 2002.

45: Kohgo Y, Niitsu Y. The nature of storage iron. Nihon Ketsueki Gakkai Zasshi. 45:1221-8, 1982.

【総説(和文)】
1. 高後 裕、須藤大輔、一石英一郎、村田一素、佐藤貴一、大竹孝明. 鉄過剰症(ヘモクロマトーシス) 日本臨床 印刷中
2.高後 裕、佐々木勝則、大竹孝明:分子レベルからみた鉄代謝の概念 日本透析医会雑誌:31:294-299、2016.
3.大竹孝明、高後 裕: 知っておきたい肝胆膵疾患.ヘモクロマトーシス 肝・胆・膵:73:291-297、2016.
4. 大竹 孝明, 高後 裕.メタボリック症候群と飲酒. 日本消化器病学会雑誌:109: 1535-1540, 2012.
5. 高後 裕, 大竹 孝明. 飲酒の血液マーカー. 日本医師会雑誌;140:巻9号 1895,2011
6. 大竹 孝明, 高後 裕. 酸化ストレスとNAFLD. 診断と治療; 99:1549-1553,2011.
7. 大平 基之,高後 裕.アルコール性肝障害(ASH) 診断と検査. 日本内科学会雑誌:95: 22-27, 2006.

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高後 裕先生 の所属する医療機関

国際医療福祉大学病院

TEL: 0287-37-2221

国際医療福祉大学病院

栃木県那須塩原市井口537-3

JR東北本線(宇都宮線)「西那須野駅」 無料シャトルバス運行あり 地域バス(ゆーバス)も利用可能 車10分

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高後 裕 先生 の記事