中原 剛士 なかはら たけし 先生

来歴等

略歴

1999年 九州大学医学部 卒業
1999年 同大学皮膚科 入局
2002年 九州大学大学院医学研究院博士課程 入学
2005年 同 修了
2005年 米国スローンケタリング記念がんセンター 留学
2008年 九州大学病院 皮膚科 助教
2013年 九州大学病院 皮膚科 講師
2013年 九州大学大学院医学研究院体表感知学講座 准教授
2018年 九州大学病院 皮膚科学 診療准教授
2021年 九州大学大学院医学研究院皮膚科学分野 教授

論文

• 1. Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells. Int Immunol 16(12):1701-9, 2004

  Nakahara T, Uchi H, Urabe K, Chen Q, Furue M, Moroi Y

• 2. Intermittent topical corticosteroid/tacrolimus　sequential therapy improves lichenification and chronic papules more efficiently than intermittent topical corticosteroid/emollient sequential therapy in patients with atopic dermatitis.J Dermatol 31(7):524-8, 2004

  Nakahara T, Koga T, Fukagawa S, Uchi H, Furue M

• 3. Engagement of human monocyte-derived dendritic cells into interleukin (IL)-12 producers by IL-1beta + interferon (IFN)-gamma. Clin Exp Immunol 139(3):476-82, 2005

  Nakahara T, Urabe K, Fukagawa S, Uchi H, Inaba K, Furue M, Moroi Y

• 4. Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs. Blood 15(22):4384-92, 2010

  Nakahara T, Uchi H, Lesokhin AM, Avogadri F, Rizzuto GA, Hirschhorn-Cymerman D, Panageas KS, Merghoub T, Wolchok JD, Houghton AN

• 5. Neuronatin is related to keratinocyte differentiation by up-regulating involucrin.J Dermatol Sci 73(3):225-31, 2014

  Dugu L, Nakahara T, Wu Z, Uchi H, Liu M, Hirano K, Yokomizo T, Furue M

• 6. Expression of CD10 predicts tumor progression and unfavorable prognosis in malignant melanoma.J Am Acad Dermatol. 65(6):1152-60, 2011

  Oba J, Nakahara T, Hayashida S, Kido M, Xie L, Takahara M, Uchi H, Miyazaki S, Abe T, Hagihara A, Moroi Y, Furue M

• 7. Expression of programmed death receptor ligand 1 in melanoma may indicate tumor progression and poor patient survival.J Am Acad Dermatol 70(5):954-6, 2014

  Oba J, Nakahara T, Abe T, Hagihara A, Moroi Y, Furue M

• 8. Reduction of serum TARC levels in atopic dermatitis by topical anti-inflammatory treatments. Asian Pac J Allergy Immunol 32 (3):240-5, 2014

  Yasukochi Y, Nakahara T, Abe T, Kido-Nakahara M, Kohda F, Takeuchi S, Hagihara A, Furue M

• 9. Changes in sebum levels and the development of acneiform rash in patients with non-small cell lung cancer after treatment with EGFR inhibitors.Onco Targets Ther 8:259-63, 2015

  Nakahara T, Moroi Y, Takayama K, Itoh E, Kido-Nakahara M, Nakanishi Y, Furue M

• 10. Mutual upregulation of endothelin-1 and IL-25 in atopic dermatitis.Allergy 70(7):846-54, 2015

  Aktar MK, Kido-Nakahara M, Furue M, Nakahara T

• 11. Analysis of sebum lipid composition and the development of acneiform rash before and after administration of egfr inhibitor.Curr Oncol 22(2):e124-7, 2015

  Nakahara T, Moroi Y, Takayama K, Nakanishi Y, Furue M

• 12. Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes.J Med Food 18(10):1143-9, 2015

  Nakahara T, Mitoma C, Hashimoto-Hachiya A, Takahara M, Tsuji G, Uchi H, Yan X,Hachisuka J, Chiba T, Esaki H, Kido-Nakahara M, Furue M

• 13. Early Tumor-Infiltrating Dendritic Cells Change their Characteristics Drastically in Association with Murine Melanoma Progression. J Invest Dermatol 136(1):146-53, 2016.

  Nakahara T, Oba J, Shimomura C, Kido-Nakahara M, Furue M

• 14. CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis. PLoS One 11(2):e0149285, 2016

  Oba J, Nakahara T, Hashimoto-Hachiya A, Liu M, Abe T, Hagihara A, Yokomizo T, Furue M

• 15. The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes. Exp Dermatol 25(7):532-6, 2016

  Chiba T, Nakahara T, Hashimoto-Hachiya A, Yokomizo T, Uchi H, Furue M

• 16. Chronic spontaneous urticaria: Implications of subcutaneous inflammatory cell infiltration in an intractable clinical course. J Allergy Clin Immunol 139(1):363-366, 2017

  Itoh E, Nakahara T, Murata M, Ito T, Onozuka D, Furumura M, Hagihara A, Furue M

• 17. The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. Nat Commun. 8:13946, 2017

  Yamamura K, Uruno T, Shiraishi A, Tanaka Y, Ushijima M, Nakahara T, Watanabe M, Kido-Nakahara M, Tsuge I, Furue M, Fukui Y

• 18. The pruritogenic mediator endothelin-1 shifts the dendritic cell-T-cell response toward Th17/Th1 polarization.Allergy. 73:511-515, 2018

  Nakahara T, Kido-Nakahara M, Ohno F, Ulzii D, Chiba T, Tsuji G, Furue M

• 19. Patient-oriented Eczema Measure score: A Useful Tool for Web-Based Surveys in Patients with Atopic Dermatitis. Acta Derm Venereol doi: 10.2340/00015555-3530, 2020

  Kido-Nakahara M, Nakahara T, Yasukochi Y, Ulzii D, Furue M

• 20. Topical application of endothelin receptor A antagonist attenuates imiquimod-induced psoriasiform skin inflammation.Sci Rep. 10(1):9510. doi: 10.1038/s41598-020-66490-z, 2020

  Nakahara T, Kido-Nakahara M, Ulzii D, Miake S, Fujishima K, Sakai S,ChibaT,Tsuji G, Furue M

• 21. Inhibition of mite-induced dermatitis, pruritus, and nerve sprouting in mice by the endothelin receptor antagonist bosentan Allergy 76(1):291-301, 2021

  Kido-Nakahara M, Wang B, Ohno F, Tsuji G, Ulzii D, Takemura M, Furue M, Nakahara T

SNS・ブログ等

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