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No Association Between CYP2D6*10 Genotype and Survival of Node-negative Japanese Breast Cancer Patients Receiving Adjuvant Tamoxifen Treatment. Jpn J Clin Oncol. 39(10):651-6, 2009.
Toyama T, Yamashita H, Sugiura H, Kondo N, Iwase H, Fujii Y.
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Prognostic impact of TP53INP1 gene expression in estrogen receptor α-positive breast cancer patients. Jpn J Clin Oncol. 2019 Jun 1;49(6):567-575. doi: 10.1093/jjco/hyz029.
Nishimoto M, Nishikawa S, Kondo N, Wanifuchi-Endo Y, Hato Y, Hisada T, Dong Y, Okuda K, Sugiura H, Kato H, Takahashi S, Toyama T.
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Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients. Breast Cancer Research 9:R34, 2007.
Toyama T, Zhenhuan Zhang, Mariko Nishio, Maho Hamaguchi, Naoto Kondo, Hirotaka Iwase, Hiroji Iwata, Satoru Takahashi, Hiroko Yamashita, Yoshitaka Fujii.
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Low Expression of the Snail Gene is a Good Prognostic Factor in Node-Negative Invasive Ductal Carcinomas. Jpn J Clin Oncol 36(6):357-363, 2006
Toyama T, Zhenhuan Zhang, Hirotaka Iwase, Hiroko Yamashita, Yoshiaki Ando, Maho Hamaguchi, Mitsuhiro Mizutani, Naoto Kondo, Takashi Fujita, Yoshitaka Fujii and Hiroji Iwata,
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Biweekly paclitaxel in patients with metastatic breast cancer, Int J Clin Oncol 8 (6):357-361, 2003
Toyama T, Yamashita H, Hara H, Sugiura H, Fujii Y, Iwase H,
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p33ING1b stimulates the transcriptional activity of the estrogen receptor alfa via its activation function (AF) 2 domain, J Steroid Biochem Mol Biol 87(1):57-63, 2003
Toyama T, Iwase H, Yamashita H, Hara Y, Sugiura H, Zhang Z, Fukai I, Miura Y, Riabowol K, Fujii Y,
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Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer, Cancer Letters, 189(1): 97-102, 2003
Toyama T, Iwase H, Yamashita H, Hara Y, Omoto Y, Sugiura H, Zhang Z and Fujii Y,
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Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers. BMC Cancer, 8(1):309, 2008.
Toyama T, Yamashita H, Kondo N, Okuda K, Takahashi S, Sasaki H, Sugiura H, Iwase H, Fujii Y.
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Successful management of breast cancer with liver metastases with medroxyprogesterone acetate treatment , Int J Clin Oncol, 6(6):306-309,2001
Toyama T, Yamashita H, Hara Y, Hikosaka Y, Kobayashi S, Iwase H
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High expression of LMTK3 is an independent factor indicating a poor prognosis in estrogen receptor α-positive breast cancer patients. Jpn J Clin Oncol. 44(10):889-97, 2014.
Asano T, Sato S, Yoshimoto N, Endo Y, Hato Y, Dong Yu, Takahashi S, Fujii Y, Toyama T.
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Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells. iScience. 21;10:23-39, 2018.
Loh JT, Lim TJF, Ikumi K, Matoba T, Janela B, Gunawan M, Toyama T, Bunjamin M, Ng LG, Poidinger M, Morita A, Ginhoux F, Yamazaki S, Lam KP, Su IH.
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Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer. Int J Cancer. 2018 Nov 28. doi: 10.1002/ijc.32024. [Epub ahead of print]
Matoba T, Imai M, Ohkura N, Kawakita D, Ijichi K, Toyama T, Morita A, Murakami S, Sakaguchi S, Yamazaki S.
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Effects of serum estradiol and progesterone on estrogen-regulated gene expression in breast cancers of premenopausal patients. Jpn J Clin Oncol. 2018 Nov 5. doi: 10.1093/jjco/hyy156. [Epub ahead of print]
Wanifuchi-Endo Y, Asano T, Kondo N, Hato Y, Dong Y, Hisada T, Nishikawa S, Kato H, Takahashi S, Okuda K, Yamashita H, Toyama T.
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Validation of the 21-gene test as a predictor of clinical response to neoadjuvant hormonal therapy for ER+, HER2-negative breast cancer: the TransNEOS study. Breast Cancer Res Treat. 2018 Sep 21. doi: 10.1007/s10549-018-4964-y. [Epub ahead of print]
Iwata H, Masuda N, Yamamoto Y, Fujisawa T, Toyama T, Kashiwaba M, Ohtani S, Taira N, Sakai T, Hasegawa Y, Nakamura R, Akabane H, Shibahara Y, Sasano H, Yamaguchi T, Sakamaki K, Bailey H, Cherbavaz DB, Jakubowski DM, Sugiyama N, Chao C, Ohashi Y.
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A randomized phase II study evaluating pyridoxine for the prevention of hand-foot syndrome associated with capecitabine therapy for advanced or metastatic breast cancer. Breast Cancer 25(6):729-735, 2018.
Toyama T, Yoshimura A, Hayashi T, Kobayashi N, Saito K, Tsuneizumi M, Sawaki M, Hattori M, Nakada T, Yokota I, Iwata H.
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Everolimus Plus Endocrine Therapy for Postmenopausal Women With Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Clinical Trial. JAMA Oncol. 4(7):977-984, 2018.
Royce M, Bachelot T, Villanueva C, Özgüroglu M, Azevedo SJ, Cruz FM, Debled M, Hegg R, Toyama T, Falkson C, Jeong J, Srimuninnimit V, Gradishar WJ, Arce C, Ridolfi A, Lin C, Cardoso F.
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Genetic and environmental factors and serum hormones, and risk of estrogen receptor-positive breast cancer in pre- and postmenopausal Japanese women. Oncotarget. 8(39):65759-65769, 2017.
Guo J, Sueta A, Nakamura K, Yoshimoto N, Baba M, Ishida N, Hagio K, Toyama T, Iwase H, Tamakoshi A, Yamashita H,
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A randomized phase II study of nab-paclitaxel as first-line chemotherapy in patients with HER2-negative metastatic breast cancer. Cancer Sci. 108(5):987-994, 2017.
Tamura K, Inoue K, Masuda N, Takao S, Kashiwaba M, Tokuda Y, Iwata H, Yamamoto N, Aogi K, Saeki T, Nakayama T, Sato N, Toyama T, Ishida T, Arioka H, Saito M, Ohno S, Yamauchi H, Yamada K, Watanabe J, Ishiguro H, Fujiwara Y.
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Identification of targets of tumor suppressor microRNA-34a using a reporter library system. Proc Natl Acad Sci U S A. 114(15):3927-3932, 2017.
Ito Y, Inoue A, Seers T, Hato Y, Igarashi A, Toyama T, Taganov KD, Boldin MP, Asahara H.
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HER2 mutation status in Japanese HER2-positive breast cancer patients. Breast Cancer. 23(6):902-907, 2016.
Endo Y, Dong Y, Kondo N, Yoshimoto N, Asano T, Hato Y, Nishimoto M, Kato H, Takahashi S, Nakanishi R, Toyama T.
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Prognostic impact of a single-nucleotide polymorphism near the CTSO gene in hormone receptor-positive breast cancer patients. Int J Clin Oncol. 21(3):539-47, 2016
Hato Y, Kondo N, Yoshimoto N, Endo Y, Asano T, Dong Y, Nishimoto M, Takahashi S, Fujii Y, Nakanishi R, Toyama T.
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Taxanes versus S-1 as the first-line chemotherapy for metastatic breast cancer (SELECT BC): an open-label, non-inferiority, randomised phase 3 trial. Lancet Oncol. 17(1):90-8, 2016.
Takashima T, Mukai H, Hara F, Matsubara N, Saito T, Takano T, Park Y, Toyama T, Hozumi Y, Tsurutani J, Imoto S, Watanabe T, Sagara Y, Nishimura R, Shimozuma K, Ohashi Y; SELECT BC study group.
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Immunohistochemical determination of arylamine N-acetyltransferase 1 (NAT1) as the target of miR-1290 and prognostic biomarker of breast cancer. BMC Cancer. 14(1):990, 2014.
Endo Y, Yamashita H, Takahashi S, Sato S, Yoshimoto N, Asano T, Hato Y, Dong Y, Fujii Y, Toyama T.
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Differential expression of estrogen receptor α, β1, and β2 in lobular and ductal breast cancer. Proc Natl Acad Sci USA. 111(5):1933-8, 2014.
Huang B, Omoto Y, Iwase H, Yamashita H, Toyama T, Coombes RC, Filipovic A, Warner M. Gustafsson JA.
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HER2 Mutation Status in Japanese HER2-negative Breast Cancer Patients. Jpn J Clin Oncol. 44(7):619-23. 2014.
Endo Y, Dong Y, Yoshimoto N, Asano T, Hato Y, Yamashita H, Sato S, Takahashi S, Fujii Y, Toyama T.
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High expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patients. Jpn J Clin Oncol. 42(4):256-63, 2012.
Toyama T, Kondo N, Endo Y, Sugiura H, Yoshimoto N, Iwasa M, Takahashi S, Fujii Y, Yamashita H.
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Suppression of ING1 expression in sporadic breast cancer, Oncogene 18(37):5187-5193,1999
Toyama T，Iwase H，Watson P，Muzik H，Saettler E，Magliocco A，DiFrancesco L，Forsyth P，Garkavtsev I，Kobayashi S，Riabowol K,
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Microsatellite instability in in situ and invasive sporadic breast cancers of Japanese women, Cancer Letters，108(2):205-209, 1996
Toyama T，Iwase H，Iwata H，Hara Y，Omoto Y，Suchi M，Kato T，Nakamura T，Kobayashi S,
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Microsatellite Instability in sporadic human breast cancers, Int J Cancer，68(4):447-451, 1996
Toyama T，Iwase H，Yamashita H，Iwata H，Yamashita T，Ito K，Hara Y，Suchi M，Kato T，Nakamura T，Kobayashi S,
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Pathogenesis of thymolipoma：Report of three cases, Surg Today，25(1)：86-88, 1995
Toyama T，Mizuno T，Masaoka A，Shibata K，Yamakawa Y，Niwa H，Torii K,
