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1. TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.
Yamanishi Y, Kitaura J, Izawa K, Kaitani A, Komeno Y, Nakamura M, Yamazaki S, Enomoto Y, Oki T, Akiba H, Abe T, Komori T, Morikawa Y, Kiyonari H, Takai T, Okumura K, Kitamura T. J Exp Med. 2010 Jul 5;207(7):1501-11. doi: 10.1084/jem.20090581. Epub 2010 Jun 21.
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2. Transforming growth factor-β-stimulated clone-22 is a negative-feedback regulator of Ras?/?Raf signaling: Implications for tumorigenesis.
Nakamura M, Kitaura J, Enomoto Y, Lu Y, Nishimura K, Isobe M, Ozaki K, Komeno Y, Nakahara F, Oki T, Kume H, Homma Y, Kitamura T. Cancer Sci. 2012 Jan;103(1):26-33.
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3. Association between lower urinary tract symptoms and sexual dysfunction assessed using the core lower urinary tract symptom score and International Index of Erectile Function-5 questionnaires.
Nakamura M, Fujimura T, Nagata M, Hosoda C, Suzuki M, Fukuhara H, Enomoto Y, Nishimatsu H, Kume H, Igawa Y, Homma Y. Aging Male. 2012 Jun;15(2):111-4.
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4. Opposing Effects of Circadian Clock Genes Bmal1 and Period2 in Regulation of VEGF-Dependent Angiogenesis in Developing Zebrafish.
Jensen LD, Cao Z, Nakamura M, Yang Y, Br?utigam L, Andersson P, Zhang Y, Wahlberg E, L?nne T, Hosaka K, Cao Y. Cell Rep. 2012 Aug 30;2(2):231-41. Epub 2012 Aug 9.
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5. Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodeling and metastasis.
Hosaka K, Yang Y, Seki T, Nakamura M, Andersson P, Rouhi P, Yang X, Jensen L, Lim S, Feng N, Xue Y, Li X, Larsson O, Ohhashi T, Cao Y. Nat Commun. 2013;4:2129. doi: 10.1038/ncomms3129.
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6. Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.
Wang J, Cao Z, Zhang XM, Nakamura M, Sun M, Hartman J, Harris RA, Sun Y, Cao Y. Cancer Res. 2015 Jan 15;75(2):306-15. doi: 10.1158/0008-5472. CAN-14-2819. Epub 2014 Dec 9.PMID: 25492861
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7. VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish.
Jensen LD, Nakamura M, Br?utigam L, Li X, Liu Y, Samani NJ, Cao Y. PNAS. 2015 Oct 19.pii: 201510245.
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8. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages.
Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, Yang X, Nakamura M, Wang J, Zhuang R, Morikawa H, Xue Y, Braun H, Beyaert R, Samani N, Nakae S, Hams E, Dissing S, Fallon PG, Langer R, Cao Y. Nat Commun. 2016 May 6;7:11385.
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9. Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis.
Lim S, Hosaka K, Nakamura M, Cao Y. Oncotarget. 2016 Jun 21;7(25):38282-38291.
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10. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat.
Seki T, Hosaka K, Lim S, Fischer C, Honek J, Yang Y, Andersson P, Nakamura M, N?slund E, Yl?-Herttuala S, Sun M, Iwamoto H, Li X, Liu Y, Samani NJ, Cao Y. Nat Commun. 2016 Aug 5;7:12152.
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11. Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism.
Yang Y, Zhang Y, Iwamoto H, Hosaka K, Seki T, Andersson P, Lim S, Fischer C, Nakamura M, Abe M, Cao R, Skov PV, Chen F, Chen X, Lu Y, Nie G, Cao Y. Nat Commun. 2016 Sep 1;7:12680
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12. Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production.
Nakamura M, Zhang Y, Yang Y, Sonmez C, Zheng W, Huang G, Seki T, Iwamoto H, Ding B, Yin L, Foukakis T, Hatschek T, Li X, Hosaka K, Li J, Yu G, Wang X, Liu Y, and Cao Y. PNAS 2017 ; published ahead of print Oct. 23
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13. A miR-327?FGF10?FGFR2-mediated autocrine signaling mechanism controls white fat browning.
Fischer C, Seki T, Lim S, Nakamura M, Andersson P, Yang Y, Honek J, Wang Y, Gao Y, Chen F, Samani NJ, Zhang J, Miyake M, Oyadomari S, Yasue A, Li X, Zhang Y, Liu Y, Cao Y. Nat Commun. 2017; 8: 2079. Published online 2017 Dec 12. doi: 10.1038/s41467-017-02158-z
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14. Dual roles of endothelial FGF-2-FGFR1-PDGF-BB and perivascular FGF-2-FGFR2- PDGFRβ signaling pathways in tumor vascular remodeling.
Hosaka K, Yang Y, Nakamura M, Andersson P, Yang X, Zhang Y, Seki T, Scherzer M, Dubey O, Wang X, Cao Y. Cell Discov. 2018 Jan 16;4:3. doi: 10.1038/s41421-017-0002-1. eCollection 2018.
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15. Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.
Iwamoto H, Abe M, Yang Y, Cui D, Seki T, Nakamura M, Hosaka K, Lim S, Wu J, He X, Sun X, Lu Y, Zhou Q, Shi W, Torimura T, Nie G, Li Q, Cao Y. Cell Metab. 2018 Jul 3;28(1):104-117.e5. doi:10.1016/j.cmet.2018.05.005. Epub 2018 May 31.
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16. Aggressive Cancer Behavior of Latent Gleason Pattern 5 in Prostatectomy Specimens.
Fujimura T, Fukuhara H, Yamada Y, Taguchi S, Sugihara T, Niimi A, Nakamura M, Nakagawa T, Igawa Y, Homma Y, Kume H. Anticancer Res. 2018 Nov;38(11):6529-6535. doi: 10.21873/anticanres.13018.
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17. Immune-related adverse events predict the therapeutic efficacy of pembrolizumab in urothelial cancer patients.
Kawai T, Sato Y, Makino K, Yamada Y, Nomiya A, Nakamura M, Yamada D, Suzuki M, Igawa Y, Kume H. Eur J Cancer. 2019 Jul;116:114-115. doi: 10.1016/j.ejca.2019.05.017. Epub 2019 Jun 10. PMID: 31195355
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18. Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells.
Nakato R, Wada Y, Nakaki R, Nagae G, Katou Y, Tsutsumi S, Nakajima N, Fukuhara H, Iguchi A, Kohro T, Kanki Y, Saito Y, Kobayashi M, Izumi-Taguchi A, Osato N, Tatsuno K, Kamio A, Hayashi-Takanaka Y, Wada H, Ohta S, Aikawa M, Nakajima H, Nakamura M, McGee RC, Heppner KW, Kawakatsu T, Genno M, Yanase H, Kume H, Senbonmatsu T, Homma Y, Nishimura S, Mitsuyama T, Aburatani H, Kimura H, Shirahige K. Epigenetics Chromatin. 2019 Dec 19;12(1):77. doi: 10.1186/s13072-019-0319-0. PMID: 31856914
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19. Inverted papilloma of the urinary bladder shows fluorescence on photodynamic diagnosis using 5-aminolevulinic acid.
Oshina T, Kawai T, Sato Y, Miyakawa J, Miyama Y, Makino K, Akiyama Y, Yamada Y, Nakamura M, Yamada D, Suzuki M, Ushiku T, Kume H. Photodiagnosis Photodyn Ther. 2020 Jun;30:101766. doi: 10.1016/j.pdpdt.2020.101766. Epub 2020 Apr 18. PMID: 32311542
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20. Comparison of perioperative outcomes in elderly (age ≧ 75 years) vs. younger men undergoing robot-assisted radical prostatectomy.MID: 32497131
Yamada Y, Teshima T, Fujimura T, Sato Y, Nakamura M, Niimi A, Kimura N, Kakutani S, Kawai T, Yamada D, Suzuki M, Kume H. PLoS One. 2020 Jun 4;15(6):e0234113. doi: 10.1371/journal.pone.0234113. eCollection 2020.P
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21. Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors.
Hosaka K, Yang Y, Seki T, Du Q, Jing X, He X, Wu J, Zhang Y, Morikawa H, Nakamura M, Scherzer M, Sun X, Xu Y, Cheng T, Li X, Liu X, Li Q, Liu Y, Hong A, Chen Y, Cao Y. Nat Commun. 2020 Jul 24;11(1):3704. doi: 10.1038/s41467-020-17525-6. PMID: 32709869
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22. The impact of complications after initial prostate biopsy on repeat protocol biopsy acceptance rate. Results from the Prostate Cancer Research International: Active Surveillance JAPAN study.
Tohi Y, Kato T, Matsumoto R, Shinohara N, Shiga K, Yokomizo A, Nakamura M, Kume H, Mitsuzuka K, Sasaki H, Egawa S, Matsumura M, Hashine K, Inokuchi J, Eto M, Baba H, Ichikawa T, Kinoshita H, Matsuda T, Kakehi Y, Sugimoto M. Int J Clin Oncol. 2020 Dec;25(12):2107-2114. doi: 10.1007/s10147-020-01761-3. Epub 2020 Aug 8. PMID: 32770439
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23. A Fatal Case of Myocarditis Following Myositis Induced by Pembrolizumab Treatment for Metastatic Upper Urinary Tract Urothelial Carcinoma.
Matsui H, Kawai T, Sato Y, Ishida J, Kadowaki H, Akiyama Y, Yamada Y, Nakamura M, Yamada D, Akazawa H, Suzuki M, Komuro I, Kume H. Int Heart J. 2020 Sep 29;61(5):1070-1074. doi: 10.1536/ihj.20-162. Epub 2020 Sep 12. PMID: 32921673.
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24. Latent prostate cancer among Japanese males: a bibliometric study of autopsy reports from 1980-2016.
Takeshima Y, Suzuki M, Miyakawa J, Tsuru I, Yamada Y, Nakamura M, Sato Y, Kawai T, Yamada D, Morikawa T, Kume H. Jpn J Clin Oncol. 2021 Jan 1;51(1):156-159. doi: 10.1093/jjco/hyaa161. PMID: 32875336
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25. Dermatomyositis associated with prostate adenocarcinoma with neuroendocrine differentiation.
Minagawa H, Kawai T, Matsumoto A, Makino K, Sato Y, Nagasaka K, Tokura M, Tanaka N, Ito E, Yamada Y, Nakamura M, Yamada D, Suzuki M, Murata T, Kume H. BMC Urol. 2021 Jan 7;21(1):8. doi: 10.1186/s12894-020-00779-z. PMID: 33413292
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26. Impact of age, body mass index, and renal function for severe hypotension caused by oral 5-aminolevulinic acid administration in patients undergoing transurethral resection of bladder tumor.
Miyakawa J, Kawai T, Makino K, Akiyama Y, Yamada Y, Nakamura M, Sato Y, Yamada D, Suzuki M, Kume H. Photodiagnosis Photodyn Ther. 2021 Mar;33:102179. doi: 10.1016/j.pdpdt.2021.102179. Epub 2021 Jan 8.
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27. Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis.
Akiyama Y, Zaitsu M, Watanabe D, Yoshimura I, Niimi A, Nomiya A, Yamada Y, Sato Y, Nakamura M, Kawai T, Yamada D, Suzuki M, Kume H, Homma Y. Sci Rep. 2021 Jan 8;11(1):105. doi: 10.1038/s41598-020-80589-3. PMID: 33420263
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28. Clinical characterization of interstitial cystitis/bladder pain syndrome in women based on the presence or absence of Hunner lesions and glomerulations.
Watanabe D, Akiyama Y, Niimi A, Nomiya A, Yamada Y, Sato Y, Nakamura M, Kawai T, Yamada D, Suzuki M, Igawa Y, Kume H, Homma Y. Low Urin Tract Symptoms. 2021 Jan;13(1):139-143. doi: 10.1111/luts.12344. Epub 2020 Aug 23. PMID: 32830459
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29. Impact of Initial Computed Tomography Findings on Management of Atypical Urinary Cytology of the Upper Urinary Tract.
Takemura K, Kawai T, Sato Y, Miyakawa J, Taguchi S, Akiyama Y, Yamada Y, Nakamura M, Yamada D, Suzuki M, Nakagawa T, Kume H. Urol Int. 2021;105(7-8):619-623. doi: 10.1159/000512978. Epub 2021 Jan 28. PMID: 33508829
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30. Novel operative technique of advancement urethral meatoplasty utilizing buccal mucosa for Vulvar Paget's disease with urethral invasion: two case reports.
Nakamura M, Hakozaki Y, Iwata S, Sato Y, Makino K, Kawai T, Yamada Y, Yamada D, Suzuki M, Omatsu J, Abe M, Hoshi K, Kume H, Igawa Y. J Med Case Rep. 2021 Mar 28;15(1):136. doi: 10.1186/s13256-021-02729-1.
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31. Granulomatous prostatitis with high suspicion of prostatic adenocarcinoma on radiological imaging.
Ambe Y, Nakamura M (Corresponding author), Shirakawa N, Inatsu H, Amakawa R, Inoue Y, Yoshimatsu T, Miura S, Morikawa T, Kusakabe M, Shiga Y. IJU Case Rep. 2021 May 6;4(4):247-249. doi: 10.1002/iju5.12300. eCollection 2021 Jul. PMID: 34258540
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32. Assessment of surgical outcomes of off-clamp open partial nephrectomy without renorrhaphy for ?T1b renal tumours.
Nakamura M, Ambe Y, Teshima T, Shirakawa N, Inatsu H, Amakawa R, Inoue Y, Yoshimatsu T, Imai S, Kusakabe M, Morikawa T, Kameyama S, Shiga Y. Int J Clin Oncol. 2021 Jun 16. doi: 10.1007/s10147-021-01966-0. PMID: 34136964
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33. Immune-related dermatitis during combined treatment with pembrolizumab and axitinib in a patient with metastatic renal cell\x92carcinoma with stasis dermatitis.
Imai S, Nakamura M (Corresponding author), Chujo S, Ooki R, Inoue Y, Horiuchi H, Morikawa T, Uchino K, Igarashi A, Shiga Y. IJU Case Rep. 2021 Aug 5;4(6):386-390. doi: 10.1002/iju5.12356. eCollection 2021 Nov. PMID: 34755064
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34. Early recurrence of bladder cancer in the colon after robot-assisted radical cystectomy: Disappearance following dose-dense methotrexate, vinblastine, doxorubicin and cisplatin treatment.
Noda M, Nakamura M (Corresponding author), Kawai T, Sato Y, Yamada Y, Akiyama Y, Yamada D, Suzuki M, Kume H. IJU Case Rep. 2021 Sep 8;4(6):429-432. doi: 10.1002/iju5.12370. eCollection 2021 Nov. PMID: 34755076
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35. Micropetrosis in hemodialysis patients.
Yajima A, Tsuchiya K, Burr DB, Murata T, Nakamura M, Inaba M, Tominaga Y, Tanizawa T, Nakayama T, Ito A, Nitta K. Bone Rep. 2021 Nov 27;15:101150. doi: 10.1016/j.bonr.2021.101150. eCollection 2021 Dec. PMID: 3492672
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36. Deferred radical prostatectomy in patients who initially elected for active surveillance: a multi-institutional, prospective, observational cohort of the PRIAS-JAPAN study.
Int J Clin Oncol. Tohi Y, Kato T, Nakamura M, Matsumoto R, Sasaki H, Mitsuzuka K, Inokuchi J, Hashine K, Yokomizo A, Naito H, Hara I, Kawamura N, Inoue M, Fukuhara H, Maruyama S, Sakamoto S, Saito T, Egawa S, Kakehi Y, Sugimoto M. Int J Clin Oncol. 2022 Jan;27(1):194-201. doi: 10.1007/s10147-021-02041-4. Epub 2021 Oct 2. PMID: 34599725.
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37. Impact of health-related quality of life on repeat protocol biopsy compliance on active surveillance for favorable prostate cancer: results from a prospective cohort in the PRIAS-JAPAN study.
Tohi Y, Kato T, Yokomizo A, Mitsuzuka K, Tomida R, Inokuchi J, Matsumoto R, Saito T, Sasaki H, Inoue K, Kinoshita H, Fukuhara H, Maruyama S, Sakamoto S, Tanikawa T, Egawa S, Ichikura H, Abe T, Nakamura M, Kakehi Y, Sugimoto M, Urol Oncol. 2022 Feb;40(2):56.e9-56.e15. doi: 10.1016/j.urolonc.2021.05.003
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38. Cumulative Incidence and Clinical Risk Factors of Radiation Cystitis after Radiotherapy for Prostate Cancer.
Makino K, Sato Y, Takenaka R, Yamashita H, Akiyama Y, Yamada Y, Nakamura M, Kawai T, Yamada D, Suzuki M, Kume H. Urol Int. 2022 Mar 15:1-7. doi: 10.1159/000521723. Epub ahead of print. PMID: 35290980.
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39. Predictive factors for postoperative renal function after off-clamp, non-renorrhaphy partial nephrectomy.
Nakamura M, Kameyama S, Ambe Y, Teshima T, Izumi T, Tsuru I, Inoue Y, Yoshimatsu T, Inatsu H, Amakawa R, Kusakabe M, Morikawa T, Shiga Y. Transl Androl Urol. 2022 Sep;11(9):1226-1233. doi: 10.21037/tau-22-321.
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40. Time to castration resistance is a novel prognostic factor of cancer-specific survival in patients with nonmetastatic castration-resistant prostate cancer.
Hakozaki Y, Yamada Y, Kawai T, Nakamura M, Takeshima Y, Iwaki T, Teshima T, Kinoshita Y, Fujii Y, Akiyama Y, Sato Y, Yamada D, Suzuki M, Kashiwagi-Hakozaki M, Ushiku T, Kume H. Sci Rep. 2022 Sep 28;12(1):16202. doi: 10.1038/s41598-022-20319-z.
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41. Preservation of pelvic floor muscles contributes to early continence recovery after robot-assisted radical prostatectomy.
Nakamura M, Yamada Y, Sato Y, Honda K, Yamada D, Kawai T, Akiyama Y, Suzuki M, Kume H. PLoS One. 2022 Oct 7;17(10):e0275792. doi: 10.1371/journal.pone.0275792. eCollection 2022.
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42. Evaluation of trends in prescription drugs for overactive bladder in Japanese patients.
Suzuki M, Yamamoto M, Shiratori T, Naito A, Nakamura M. Int J Urol. 2022 Dec 7. doi: 10.1111/iju.15117
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43. Low hemoglobin and PSA kinetics are prognostic factors of overall survival in metastatic castration-resistant prostate cancer patients.
Hakozaki Y, Yamada Y, Takeshima Y, Taguchi S, Kawai T, Nakamura M, Iwaki T, Teshima T, Kinoshita Y, Akiyama Y, Sato Y, Yamada D, Suzuki M, Kume H. Sci Rep. 2023 Feb 15;13(1):2672. doi: 10.1038/s41598-023-29634-5.
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44. Trends in surgical treatment for prostate cancer: Analysis of National Database Open Data in Japan.
Nakamura M, Suzuki M, Izumi T, Tsuru I, Muraki Y, Kume H. Glob Health Med. 2023 Feb 28;5(1):62-63. doi; 10.35772/ghm.2022.01065
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【和文】
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1. 当院における75歳以上の前立腺癌に対するロボット支援前立腺全摘除後の尿失禁の状況と術後排尿機能に影響を与える因子の検討
手島太郎, 中村真樹, 佐藤悠介, 川合剛人, 山田大介, 松本明彦, 鈴木基文, 井川靖彦, 久米春喜, 松永明子 日本老年泌尿器科学会誌 32(1): 194-194, 2019.
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2. 高齢者の泌尿器がん：高齢者腎臓がんの治療前評価や治療上の問題点
中村真樹, 久米春喜 日本老年泌尿器科学会誌 33(2): 19-24, 2020.
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3. 男性の排尿姿勢と排尿パラメータとの関係
鈴木基文, 渡邉大仁, 中村真樹, 佐藤悠佑, 川合剛人, 久米春喜日本老年泌尿器科学会誌 33(1): 115-115, 2020.
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4. 骨盤底筋訓練（骨盤底筋トレーニング）と多職種連携
青木芳隆, 大内みふか, 森明子, 若松ひろ子, 佐藤理乃, 中村真樹, 鈴木基文 日本老年泌尿器科学会誌34(2): 24-32, 2021.
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5. 我が国における骨盤底筋トレーニング導入の歴史
青木芳隆, 大内みふか, 森明子, 若松ひろ子, 佐藤理乃, 中村真樹, 鈴木基文、日本老年泌尿器科学会誌 35(1): 171-171, 2022.
