増山 寿 ますやま ひさし 先生

来歴等

略歴

1987年 岡山大学医学部医学科 卒業
1987年 臨床研修
1991年 岡山大学大学院医学研究科 医学博士
1995年 米国セントルイス大学 客員研究員
1998年 鹿児島市立病院 医員 NICU研修
1999年 岡山大学医学部附属病院産科婦人科 助手，外来医長
2000年 文部科学省（米国ケースウエスタンリザーブ大学） 在外研究員
2001年 岡山大学医学部附属病院産科病棟 医長
2005年 岡山大学医学部産科婦人科学教室 医局長
2006年 岡山大学医学部・歯学部附属病院 講師
2008年 岡山大学病院 准教授
2008年 周産母子センター 副センター長
2012年 岡山大学大学院医歯薬学総合研究科産科・婦人科学 准教授
2017年 岡山大学大学院医歯薬学総合研究科産科・婦人科学 教授
2017年 岡山大学病院周産母子センター センター長
2019年 岡山大学病院 副病院長

論文

• Histologic Appearance and Immunohistochemistry of DNA Mismatch Repair Protein and p53 in Endometrial Carcinosarcoma: Impact on Prognosis and Insights Into Tumorigenesis. Am J Surg Pathol. 2019;43(11): 1493-1500.

  Saijo M, Nakamura K, Ida N, Nasu A, Yoshino T, Masuyama H, Yanai H.

• Assessment of glucose kinetics with real-time continuous glucose monitoring during labor. J Obstet Gynaecol Res. 2019;45(9): 1851-1859.

  Maki J, Eto E, Tamada S, Mitsui T, Hayata K, Nakamura K, Hiramatsu Y, Masuyama H.

• Short-Term Prediction of Adverse Outcomes Using the sFlt-1 (Soluble fms-Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) Ratio in Asian Women With Suspected Preeclampsia. Hypertension. 2019;74(1): 164-172.

  Bian X, Biswas A, Huang X, Lee KJ, Li TK, Masuyama H, Ohkuchi A, Park JS, Saito S, Tan KH, Yamamoto T, Dietl A, Grill S, Verhagen-Kamerbeek WDJ, Shim JY, Hund M.

• Sarcopenia Is Not a Prognostic Factor of Outcome in Patients With Cervical Cancer Undergoing Concurrent Chemoradiotherapy or Radiotherapy. Anticancer Res. 2019;39(2): 933-939.

  Matsuoka H, Nakamura K, Matsubara Y, Ida N, Nishida T, Ogawa C, Katsi K, Kanazawa S, Masuyama H.

• Classification of factors involved in nonreportable results of noninvasive prenatal testing (NIPT) and prediction of success rate of second NIPT. Prenat Diagn. 2019;39(2): 100-106.

  Suzumori N, Sekizawa A, Takeda E, Samura O, Sasaki A, Akaishi R, Wada S, Hamanoue H, Hirahara F, Kuriki H, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Yamashita T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Endo M, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Nagamatsu T, Watanabe A, Nishikawa N, Hamajima N, Shirato N, Yotsumoto J, Nishiyama M, Koide K, Hirose T, Sago H.

• The Influence of Chemotherapy-Induced Peripheral Neuropathy on Quality of Life of Gynecologic Cancer Survivors. Int J Gynecol Cancer. 2018;28(7): 1394-1402.

  Matsuoka H, Nakamura K, Matsubara Y, Ida N, Saijo M, Ogawa C, Masuyama H.

• Clinical impact of endometrial cancer stratified by genetic mutational profiles, POLE mutation, and microsatellite instability. PLoS One. 2018;13(4): e0195655.

  Haruma T, Nagasaka T, Nakamura K, Haraga J, Nyuya A, Nishida T, Goel A, Masuyama H, Hiramatsu Y.

• Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy. Eur J Obstet Gynecol Reprod Biol. 2018;224: 165-169.

  Suzumori N, Sekizawa A, Ebara T, Samura O, Sasaki A, Akaishi R, Wada S, Hamanoue H, Hirahara F, Izumi H, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Yamashita T, Okai T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Nagamatsu T, Watanabe A, Shirato N, Yotsumoto J, Nishiyama M, Hirose T, Sago H.

• Interaction between orexin A and bone morphogenetic protein system on progesterone biosynthesis by rat granulosa cells. J Steroid Biochem Mol Biol. 2018;181: 73-79.

  Fujita S, Hasegawa T, Nishiyama Y, Fujisawa S, Nakano Y, Nada T, Iwata N, Kamada Y, Masuyama H, Otsuka F.

• Assessment of resting energy expenditure and body composition in Japanese pregnant women with diabetes. J Diabetes Investig. 2018;9(4): 959-966.

  Eto E, Maki J, Tamada S, Mitsui T, Hayata K, Hiramatsu Y, Masuyama H.

• Sarcopenia Is an Important Prognostic Factor in Patients With Cervical Cancer Undergoing Concurrent Chemoradiotherapy. Int J Gynecol Cancer. 2018;28(1): 168-175.

  Kiyotoki T, Nakamura K, Haraga J, Omichi C, Ida N, Saijo M, Nishida T, Kusumoto T, Masuyama H.

• The Influence of Adverse Effects on Quality of Life of Survivors of Gynecologic Cancer. Int J Gynecol Cancer. 2017;27(9): 2014-2019.

  Omichi C, Nakamura K, Haraga J, Ida N, Saijo M, Nishida T, Kusumoto T, Masuyama H.

• Reply to "Letter to the Editor" by M. Saijo et al. "Glasgow prognostic score is predictive of prognosis for patients with endometrial cancer Eur J Obstet Gynecol Reprod Biol. 2017;216: 260.

  Saijo M, Nakamura K, Masuyama H, Ida N, Haruma T, Kusumoto T, Seki N, Hiramatsu Y.

• Current status of non-invasive prenatal testing in Japan. J Obstet Gynaecol Res. 2017;43(8): 1245-1255.

  Samura O, Sekizawa A, Suzumori N, Sasaki A, Wada S, Hamanoue H, Hirahara F, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Nakayama S, Okai T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Kido Y, Fukao T, Miharu N, Nagamatsu T, Watanabe A, Hamajima N, Hirose M, Sanui A, Shirato N, Yotsumoto J, Nishiyama M, Hirose T, Sago H.

• Comparison of Kidney Function between Gestational Hypertension and Preeclampsia. Acta Med Okayama. 2017;71(2):161-169.

  Nobumoto E, Masuyama H, Maki J, Eguchi T, Tamada S, Mitsui T, Eto E, Hayata K, Hiramatsu Y.

• Glasgow prognostic score is a prognosis predictor for patients with endometrial cancer. Eur J Obstet Gynecol Reprod Biol. 2017; 210: 355-359.

  Saijo M, Nakamura K, Masuyama H, Ida N, Haruma T, Kusumoto T, Seki N, Hiramatsu Y.

• Sex differences in early growth during the first three years of life in offspringfrom mothers with pregnancy-induced hypertension. Pregnancy Hypertens. 2016 Oct;6(4):361-366.

  Mitsui T, Masuyama H, Eguchi T, Tamada S, Eto E, Hayata K, Hiramatsu Y.

• Radical Hysterectomy Plus Concurrent Chemoradiation/Radiation Therapy Is Negatively Associated With Return to Work in Patients With Cervical Cancer. Int J Gynecol Cancer. 2017 Jan;27(1):117-122.

  Nakamura K, Masuyama H, Ida N, Haruma T, Kusumoto T, Seki N, Hiramatsu Y.

• Sex differences in early growth during the first three years of life in offspring from mothers with pregnancy-induced hypertension. Pregnancy Hypertens 6: 361-366, 2016.

  T. Mitsui, H. Masuyama, T. Eguchi, S. Tamada, E. Eto, K. Hayata, Y. Hiramatsu.

• Return to work after cancer treatment of gynecologic cancer in Japan. BMC Cancer 16: 558, 2016.

  K. Nakamura, H. Masuyama, T. Nishida, J. Haraga, N. Ida, M. Saijo, T. Haruma, T. Kusumoto, N. Seki, Y. Hiramatsu

• Dimethylesculetin ameliorates maternal glucose intolerance and fetal overgrowth in high fat diet-fed pregnant mice via constitutive androstane receptor. Mol Cell Biochem 419: 185-192, 2016.

  H. Masuyama, T. Mitsui, J. Maki, K. Tani, K. Nakamura, Y. Hiramatsu.

• Japan NIPT Consortium: A survey on awareness of genetic counseling for non-invasive prenatal testing: The first year experience in Japan. J Hum Genet. 61:995-1001, 2016.

  J. Yotsumoto, A. Sekizawa, N. Suzumori, T. Yamada, O. Samura, M. Nishiyama, K. Miura, H. Sawai, J. Murotsuki, M. Kitagawa, Y. Kamei, H. Masuzaki, F. Hirahara, T. Endo, A. Fukushima, A. Namba, H. Osada, Y. Kasai, A. Watanabe, Y. Katagiri, N. takeshita, M. Ogawa, T. Okai, S. Izumi, H. Hamanoue, M. Inuzuka, K. Haino, N. Hamajima, H. Nishizawa, Y. Okamoto, H. Nakamura, T. Kanegawa, J. Yoshimatsu, S. Tairaku, K. Naruse, H. Masuyama, M. Hyodo, T. kaji, K. Maeda, K. Matsubara, M. Ogawa, T. Yoshizato, T. Ohba, Y. Kawano, H. Sago.

• Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anti-cancer agents in ovarian cancer cells. Int J Oncol 49: 1211-1220, 2016.

  H. Masuyama, K. Nakamura, E. Nobumoto, Y. Hiramatsu.

• The effects of paternal high-fat diet exposure on offspring metabolism with epigenetic changes in the mouse Adiponectin and Leptin gene promoters. Am J Physiol Endocrinol Metab 311(1): E236-245, 2016.

  H. Masuyama, T. Mitsui, T. Eguchi, S. Tamada, Y. Hiramatsu.

• Fetal cell-free DNA fraction in maternal plasma is affected by fetal trisomy.　J Hum Genet. 61(7): 647-652, 2016.

  N. Suzumori, T. Ebara, T. Yamada, O. Samura O, J. Yotsumoto, M. Nishiyama, K. Miura K, H. Sawai H, J. Murotsuki J, M. Kitagawa M, Y. Kamei Y, H. Masuzaki, F. Hirahara F, JS. Saldivar , N. Dharajiya, H. Sago, A. Sekizawa A; Japan NIPT Consortium, T. Endo, A. Hukushima, S. Nanba, H. Osada, Y. Kasai, A. Watanabe, Y. Katagiri, N.　Takesita, M. Ogawa, T.　Okai, SI. Izumi, H. Hamanoue, K. Haino, N. Hamajima, H. Nishizawa, Y. Okamoto, H. Nakamura, T. Kanekawa, J. Yoshimatsu, S. Tairaku, K. Naruse, H. Masuyama, M. Hyodo, T. Kaji, K. Maeda , K. Matsubara, M. Ogawa, T. Yoshizato, T. Ohba, Y. Kawano.

• Glasgow prognostic score is an independent marker for poor prognosis with all cases of epithelial ovarian cancer. Cancer Med 5(6): 1074-1080, 2016.

  C. Ohmichi, K. Nakamura, J. Haraga, H. Masuyama, Y. Hiramatsu.

• The effects of high-fat diet exposure in utero on the obesogenic and diabetogenic traits through epigenetic changes in Adiponectin and Leptin gene expression for multiple generations in female mice. Endocrinology 156(7): 2482-91, 2015.

  H. Masuyama, T. Mitsui, E. Nobumoto, Y. Hiramatsu.

• The inhibition of constitutive androstane receptor-mediated pathway enhances the effects of anticancer agents in ovarian cancer cells. Biochem Pharmacol 90: 356-366, 2014.

  Y. Wang, H. Masuyama, E. Nobumoto, G. Zhang, Y. Hiramatsu.

• Additive Effects of Maternal High Fat Diet during Lactation on Mouse Offspring. PLoS One 9(3): e92805, 2014.

  H. Masuyama, Y. Hiramatsu.

• Treatment with Constitutive Androstane Receptor Ligand during Pregnancy Prevents Insulin Resistance in Offspring from High- fat Diet-Induced Obese Pregnant Mice. Am J Physiol Endocrinol Metab 303(2): E293-300, 2012.

  H. Masuyama, Y. Hiramatsu.

著書

• 【共著】今日の治療指針2020，医学書院，東京，2020.

• 【共著】産婦人科研修ノート（改訂第3版），診断と治療社，東京，2019.

• 【共著】基礎と臨床の両側面からみた胎盤学，日本胎盤学会編，メジカルビュー社，東京，2019.

• 【共著】今日の治療指針2019，医学書院，東京，2019.

• 【共著】産婦人科手術スタンダード（改訂第2版），日本産婦人科手術学会編，メジカルビュー社，東京，2017.

• 【共著】妊婦の糖代謝異常　診療・管理マニュアル，日本糖尿病・妊娠学会編, メジカルビュー社，東京，2015.

• 【共著】研修ノート　No. 96 子宮筋腫，日本産婦人科医会，東京，2015.

• 【共著】産科診療：こんなときどうするQ&A ～一つ上を行く診療の実践～，中外医学社，東京，2015.

• 【共著】妊娠と糖尿病　母児管理のエッセンス，金芳堂，京都，2013.

• 【共著】OGS NOW13 機能温存，メジカルビュー社，東京，2013.

その他

• 【受賞】平成9年　Young Investigator Award （10th Workshop on Vitamin D, France）

• 【受賞】平成13年　Young Investigator Award（The Endocrine Society, USA）

• 【受賞】平成16年　林原賞（岡山大学医学賞）

• 【受賞】平成16年　八木賞（日本産科婦人科学会中国四国合同地方部会学会賞）

• 【受賞】平成17年　結城賞（岡山医学会賞）

• 【受賞】平成24年　岡山県保健福祉学会長賞

• 【受賞】平成28年　APSselect Award（The American Physiology Society優秀論文賞）

• 【受賞】平成29年　Outstanding reviewer award（Journal of Reproductive Immunology）