野口 智史 のぐち さとし 先生

来歴等

略歴

2006年 東京大学医学部 医学科 卒業
2006年 NTT東日本関東病院 初期研修
2008年 関東中央病院 後期研修
2010年 東京大学大学院医学系研究科 内科学専攻 入学
2014年 東京大学医学部附属病院 呼吸器内科 特任臨床医
2015年 東京大学医学部附属病院 呼吸器内科 助教
2024年 NTT東日本関東病院 呼吸器内科 医長

論文

• 1. Endoscopic reflux esophagitis and decline in pulmonary function in nonsmokers: A retrospective cohort study. Respir Investig. 2024 Jul 1;62(4):599-605.

  Enokido T, Hiraishi Y, Jo T, Urushiyama H, Saito A, Noguchi S, Hosoki K, Ishii T, Miyashita N, Fukuda K, Matsuki R, Minatsuki C, Shimamoto T, Kage H, Yamamichi N, Matsuzaki H.

• 2. Pulmonary carcinoid tumour with remarkably high levels of pro-gastrin-releasing peptide: A case report. Respir Med Case Rep. 2023 Mar 11;43:101836.

  Nakagawa N, Kawakami M, Suzuki M, Noguchi S, Mitani A, Tanaka G, Shinozaki-Ushiku A, Nagase T.

• 3. A mouse model of asthma-chronic obstructive pulmonary disease overlap induced by intratracheal papain. Allergy. 2021 Jan;76(1):390-394.

  Fukuda K, Matsuzaki H, Mikami Y, Makita K, Miyakawa K, Miyashita N, Hosoki K, Ishii T, Noguchi S, Urushiyama H, Horie M, Mitani A, Yamauchi Y, Shimura E, Nakae S, Saito A, Nagase T, Hiraishi Y.

• 4. Active mTOR in Lung Epithelium Promotes Epithelial-Mesenchymal Transition and Enhances Lung Fibrosis. Am J Respir Cell Mol Biol. 2020 Jun;62(6):699-708.

  Saito M, Mitani A, Ishimori T, Miyashita N, Isago H, Mikami Y, Noguchi S, Tarui M, Nagase T.

• 5. Development of mild drug-induced sclerosing cholangitis after discontinuation of nivolumab. Eur J Cancer. 2019 Jan;107:93-96.

  Noda-Narita S, Mizuno S, Noguchi S, Watanabe K, Nakai Y, Koike K, Kage H, Nagase T.

• 6. YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer. Int J Mol Sci. 2018 Nov 20;19(11):3674.

  Noguchi S, Saito A, Nagase T.

• 7. Acute Arterial Thrombosis during Postoperative Adjuvant Cisplatin-based Chemotherapy for Completely Resected Lung Adenocarcinoma. Intern Med. 2018 Feb 15;57(4):557-561.

  Sato C, Okuda K, Tamiya H, Yamamoto K, Hoshina K, Narumoto O, Urushiyama H, Noguchi S, Amano Y, Watanabe K, Mitani A, Kage H, Tanaka G, Yamauchi Y, Takai D, Nagase T.

• 8. Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC. Mol Cancer Res. 2017 Jul 11 doi: 10.1158/1541-7786.MCR-17-0191.

  Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.

• 9. TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts. Sci Rep. 2017 Feb 14;7:42595.

  Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, Takeshima H, Makita K, Miyashita N, Mitani A, Jo T, Yamauchi Y, Terasaki Y, Nagase T.

• 10. Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer. BMC Cancer. 2014;14:580.

  Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki HI, Kohyama T, Nagase T.

• 11. An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer. Clin Cancer Res. 2014;20(17):4660-72.

  Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T.

• 12. Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition. Recent Pat Inflamm Allergy Drug Discov. 2014;8(1):9-18.

  Noguchi S, Yamauchi Y, Takizawa H.

• 13. Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells. Hum Immunol. 2013;74(3):395-401.

  Noguchi S, Hamano E, Matsushita I, Hijikata M, Ito H, Nagase T, Keicho N.

• 14. MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells. Immunogenetics. 2013;65(2):107-14.

  Noguchi S, Hijikata M, Hamano E, Matsushita I, Ito H, Ohashi J, Nagase T, Keicho N.