樋口 佳則 ひぐち よしのり 先生

来歴等

略歴

1992年 千葉大学医学部 卒業
1992年 千葉大学医学部付属病院脳神経外科 所属
1999年 Department of Radiation Medicine and Neurosurgery, Loma Linda University Medical Center, California; Division of Neurosurgery, Duke University Medical Center, North Carolina 所属
2000年 千葉大学大学院医学研究科 博士課程修了・医学博士取得
2007年 千葉大学医学部脳神経外科 助教
2014年 千葉大学医学部脳神経外科 診療講師
2017年 千葉大学医学部脳神経外科 准教授
2023年 千葉大学教授大学院医学研究院（脳神経外科学）
2023年 千葉大学医学部附属病院 脳神経外科 科長

論文

• 1. Exposure of the dorsal root ganglion in rats to pulsed radiofrequency currents activates dorsal horn lamina I and II neurons. Neurosurgery. 2002;50(4):850-855; discussion 856.

  Higuchi Y, Nashold BS, Jr., Sluijter M, Cosman E, Pearlstein RD.

• 2. Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. Stroke. 2002;33(9):2317-2323.

  McGirt MJ, Parra A, Sheng H, Higuchi Y, Oury TD, Laskowitz DT, Pearlstein RD, Warner DS.

• 3. Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation. J Radiat Res. 2002;43 Suppl:S219-224.

  Higuchi Y, Nelson GA, Vazquez M, Laskowitz DT, Slater JM, Pearlstein RD.

• 4. Surgical complications in patients with Parkinson's disease after posteroventral pallidotomy. Neurosurgery. 2003;52(3):558-571; discussion 568-571.

  Higuchi Y, Iacono RP.

• 5. Treatment of low-grade oligodendroglial tumors without radiotherapy. Neurology. 2004;63(12):2384-2386.

  Higuchi Y, Iwadate Y, Yamaura A.

• 6. Gamma knife surgery for brain metastases: indications for and limitations of a local treatment protocol. Acta Neurochir (Wien). 2005;147(7):721-726; discussion 726.

  Serizawa T, Saeki N, Higuchi Y, Ono J, Iuchi T, Nagano O, Yamaura A.

• 7. Diagnostic value of thallium-201 chloride single-photon emission computerized tomography in differentiating tumor recurrence from radiation injury after gamma knife surgery for metastatic brain tumors. J Neurosurg. 2005;102 Suppl:266-271.

  Serizawa T, Saeki N, Higuchi Y, Ono J, Matsuda S, Sato M, Yanagisawa M, Iuchi T, Nagano O, Yamaura A.

• 8. Gamma Knife surgery for metastatic brain tumors without prophylactic whole-brain radiotherapy: results in 1000 consecutive cases. J Neurosurg. 2006;105 Suppl:86-90.

  Serizawa T, Higuchi Y, Ono J, Matsuda S, Nagano O, Iwadate Y, Saeki N.

• 9. Hyperactivity of the facial nucleus produced by chronic electrical stimulation in rats. J Clin Neurosci. 2007;14(5):459-463.

  Yamakami I, Oka N, Higuchi Y.

• 10. Transient expansion of vestibular schwannoma following stereotactic radiosurgery. J Neurosurg. 2008;109(5):811-816.

  Nagano O, Higuchi Y, Serizawa T, Ono J, Matsuda S, Yamakami I, Saeki N.

• 11. Gamma Knife surgery for metastatic brain tumors. J Neurosurg. 2008;109 Suppl:118-121.

  Serizawa T, Yamamoto M, Nagano O, Higuchi Y, Matsuda S, Ono J, Iwadate Y, Saeki N.

• 12. Three-staged stereotactic radiotherapy without whole brain irradiation for large metastatic brain tumors. Int J Radiat Oncol Biol Phys. 2009;74(5):1543-1548.

  Higuchi Y, Serizawa T, Nagano O, Matsuda S, Ono J, Sato M, Iwadate Y, Saeki N.

• 13. Hearing preservation and intraoperative auditory brainstem response and cochlear nerve compound action potential monitoring in the removal of small acoustic neurinoma via the retrosigmoid approach. J Neurol Neurosurg Psychiat (2009); 80: 218-227.

  Yamakami I, Higuchi Y, Saeki N, Wada M, Oka N.

• 14. Comparing bromocriptine effects with levodopa effects on bladder function in Parkinson's disease. Mov Disord. 2009;24(16):2386-2390.

  Uchiyama T, Sakakibara R, Yamamoto T, Ito T, Yamaguchi C, Awa Y, Yano M, Yanagisawa M, Kobayashi M, Higuchi Y, Ichikawa T, Yamanishi T, Hattori T, Kuwabara S.

• 15. Trigeminal nerve dysfunction after Gamma Knife surgery for trigeminal neuralgia: a detailed analysis. J Neurosurg. 2010;113 Suppl:184-190.

  Matsuda S, Nagano O, Serizawa T, Higuchi Y, Ono J.

• 16. Tumor shrinkage of vestibular schwannomas after Gamma Knife surgery: results after more than 5 years of follow-up. J Neurosurg. 2010;113 Suppl:122-127.

  Nagano O, Serizawa T, Higuchi Y, Matsuda S, Sato M, Yamakami I, Okiyama K, Ono J, Saeki N.

• 17. Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain. Int J Radiat Biol. 2010;86(2):145-163.

  Pearlstein RD, Higuchi Y, Moldovan M, Johnson K, Fukuda S, Gridley DS, Crapo JD, Warner DS, Slater JM.

• 18. Gamma knife surgery for 1-10 brain metastases without prophylactic whole-brain radiation therapy: analysis of cases meeting the Japanese prospective multi-institute study (JLGK0901) inclusion criteria. J Neurooncol. 2010;98(2):163-167.

  Serizawa T, Hirai T, Nagano O, Higuchi Y, Matsuda S, Ono J, Saeki N.

• 19. Gamma Knife surgery as sole treatment for multiple brain metastases: 2-center retrospective review of 1508 cases meeting the inclusion criteria of the JLGK0901 multi-institutional prospective study. J Neurosurg. 2010;113 Suppl:48-52.

  Serizawa T, Yamamoto M, Sato Y, Higuchi Y, Nagano O, Kawabe T, Matsuda S, Ono J, Saeki N, Hatano M, Hirai T.

• 20. Favorable long-term outcome of low-grade oligodendrogliomas irrespective of 1p/19q status when treated without radiotherapy. J Neurooncol. 2011;102(3):443-449.

  Iwadate Y, Matsutani T, Hasegawa Y, Shinozaki N, Higuchi Y, Saeki N.

• 21. Urinary dysfunction in early and untreated Parkinson's disease. J Neurol Neurosurg Psychiatry. 2011;82(12):1382-1386.

  Uchiyama T, Sakakibara R, Yamamoto T, Ito T, Yamaguchi C, Awa Y, Yanagisawa M, Higuchi Y, Sato Y, Ichikawa T, Yamanishi T, Hattori T, Kuwabara S.

• 22. Treatment policy for petroclival meningioma based on tumor size: aiming radical removal in small tumors for obtaining cure without morbidity. Neurosurg Rev. 2011;34(3):327-334; discussion 334-325.

  Yamakami I, Higuchi Y, Horiguchi K, Saeki N.

• 23. Subthalamic deep brain stimulation can improve gastric emptying in Parkinson's disease. Brain. 2012;135(Pt 5):1478-1485.

  Arai E, Arai M, Uchiyama T, Higuchi Y, Aoyagi K, Yamanaka Y, Yamamoto T, Nagano O, Shiina A, Maruoka D, Matsumura T, Nakagawa T, Katsuno T, Imazeki F, Saeki N, Kuwabara S, Yokosuka O.

• 24. Gamma knife thalamotomy for Parkinson disease and essential tremor: a prospective multicenter study. Neurosurgery. 2012;70(3):526-535

  Ohye C, Higuchi Y, Shibazaki T, Hashimoto T, Koyama T, Hirai T, Matsuda S, Serizawa T, Hori T, Hayashi M, Ochiai T, Samura H, Yamashiro K.

• 25. Testing different brain metastasis grading systems in stereotactic radiosurgery: Radiation Therapy Oncology Group's RPA, SIR, BSBM, GPA, and modified RPA. J Neurosurg. 2012;117 Suppl:31-37.

  Serizawa T, Higuchi Y, Nagano O, Hirai T, Ono J, Saeki N, Miyakawa A.

• 26. Long-term follow-up results of intentional 2-stage Gamma Knife surgery with an interval of at least 3 years for arteriovenous malformations larger than 10 cm(3). J Neurosurg. 2012;117 Suppl:126-134.

  Yamamoto M, Akabane A, Matsumaru Y, Higuchi Y, Kasuya H, Urakawa Y.

• 27. Validity of three recently proposed prognostic grading indexes for breast cancer patients with radiosurgically treated brain metastases. Int J Radiat Oncol Biol Phys. 2012;84(5):1110-1115.

  Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Barfod BE, Kasuya H, Urakawa Y.

• 28. Subclassification of recursive partitioning analysis Class II patients with brain metastases treated radiosurgically. Int J Radiat Oncol Biol Phys. 2012;83(5):1399-1405.

  Yamamoto M, Sato Y, Serizawa T, Kawabe T, Higuchi Y, Nagano O, Barfod BE, Ono J, Kasuya H, Urakawa Y.

• 29. Delayed complications in patients surviving at least 3 years after stereotactic radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys. 2013;85(1):53-60.

  Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Nariai T, Barfod BE, Kasuya H, Urakawa Y.

• 30. A case-matched study of stereotactic radiosurgery for patients with multiple brain metastases: comparing treatment results for 1-4 vs >/= 5 tumors: clinical article. J Neurosurg. 2013;118(6):1258-1268.

  Yamamoto M, Kawabe T, Sato Y, Higuchi Y, Nariai T, Barfod BE, Kasuya H, Urakawa Y.

• 31. Validity of two recently-proposed prognostic grading indices for lung, gastro-intestinal, breast and renal cell cancer patients with radiosurgically-treated brain metastases. J Neurooncol. 2013;111(3):327-335.

  Yamamoto M, Serizawa T, Sato Y, Kawabe T, Higuchi Y, Nagano O, Barfod BE, Ono J, Kasuya H, Urakawa Y.

• 32. Risk factors in chronic subdural hematoma: comparison of irrigation with artificial cerebrospinal fluid and normal saline in a cohort analysis. PLoS One. 2014;9(8):e103703.【IF=3.752】

  Adachi A, Higuchi Y, Fujikawa A, Machida T, Sueyoshi S, Harigaya K, Ono J, Saeki N.

• 33. Continuous intraoperative monitoring of abnormal muscle response in microvascular decompression for hemifacial spasm; a real-time navigator for complete relief. Neurosurg Rev. 2014;37(2):311-319

  Hirono S, Yamakami I, Sato M, Kado K, Fukuda K, Nakamura T, Higuchi Y, Saeki N.

• 34. Influence of antiplatelet therapy on postoperative recurrence of chronic subdural hematoma: a multicenter retrospective study in 719 patients. Clin Neurol Neurosurg. 2014;120:49-54.

  Wada M, Yamakami I, Higuchi Y, Tanaka M, Suda S, Ono J, Saeki N.

• 35. Retrosigmoid removal of small acoustic neuroma: curative tumor removal with preservation of function. J Neurosurg. 2014;121(3):554-563. doi: 10.3171/2014.6.JNS132471【IF=5.526】

  Yamakami I, Ito S, Higuchi Y.

• 36. Validity of prognostic grading indices for brain metastasis patients undergoing repeat radiosurgery. World Neurosurg. 2014;82(6):1242-1249.

  Yamamoto M, Kawabe T, Higuchi Y, Sato Y, Nariai T, Watanabe S, Barfod BE, Kasuya H.

• 37. Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study. Lancet Oncol. 2014;15(4):387-395.

  Yamamoto M, Serizawa T, Shuto T, Akabane A, Higuchi Y, Kawagishi J, Yamanaka K, Sato Y, Jokura H, Yomo S, Nagano O, Kenai H, Moriki A, Suzuki S, Kida Y, Iwai Y, Hayashi M, Onishi H, Gondo M, Sato M, Akimitsu T, Kubo K, Kikuchi Y, Shibasaki T, Goto T, Takanashi M, Mori Y, Takakura K, Saeki N, Kunieda E, Aoyama H, Momoshima S, Tsuchiya K.

• 38. Stereotactic radiosurgery in combination with up-front high-dose methotrexate as a first-line treatment for newly diagnosed primary central nervous system lymphoma. J Neurooncol. 2015;123(2):237-244.

  Hirono S, Iwadate Y, Higuchi Y, Serizawa T, Nagano O, Matsutani T, Saeki N.

• 39. Subthalamic Nucleus Deep Brain Stimulation Modulate Catecholamine Levels with Significant Relations to Clinical Outcome after Surgery in Patients with Parkinson's Disease. PLoS One. 2015;10(9):e0138462.

  Yamamoto T, Uchiyama T, Higuchi Y, Asahina M, Hirano S, Yamanaka Y, Kuwabara S.

• 40. Superolateral Orbitotomy for Intraorbital Tumors: Comparison with the Conventional Approach. J Neurol Surg B Skull Base 2016; 77: 473-478.

  Mine S, Higuchi Y, Horiguchi K, Saeki N.

• 41. Robustness of the neurological prognostic score in brain metastasis patients treated with Gamma Knife radiosurgery. J Neurosurg. 2016:1-7.

  Serizawa T, Higuchi Y, Nagano O, Matsuda S, Aoyagi K, Ono J, Saeki N, Iwadate Y, Hirai T, Takemoto S, Shibamoto Y.

• 42. Gamma knife radiosurgery in movement disorders: Indications and limitations. Mov Disord. 2017;32(1):28-35.

  Higuchi Y, Matsuda S, Serizawa T.

• 43. Cortical Venous Redness Represents Tissue Circulation Status in Patients With Moyamoya Disease. Stroke. 2017;48(6):1665-1667.

  Machida T, Higuchi Y, Nakano S, Ishige S, Fujikawa A, Akaogi Y, Shimada J, Yoshida Y, Maru S, Ono J.

• 44. Robustness of the neurological prognostic score in brain metastasis patients treated with Gamma Knife radiosurgery. J Neurosurg. 2017;127(5):1000-1006.

  Serizawa T, Higuchi Y, Nagano O, Matsuda S, Aoyagi K, Ono J, Saeki N, Iwadate Y, Hirai T, Takemoto S, Shibamoto Y.

• 45. A Multi-institutional Prospective Observational Study of Stereotactic Radiosurgery for Patients With Multiple Brain Metastases (JLGK0901 Study Update): Irradiation-related Complications and Long-term Maintenance of Mini-Mental State Examination Scores. Int J Radiat Oncol Biol Phys. 2017;99(1):31-40.

  Yamamoto M, Serizawa T, Higuchi Y, Sato Y, Kawagishi J, Yamanaka K, Shuto T, Akabane A, Jokura H, Yomo S, Nagano O, Aoyama H.

• 46. Long term follow-up on quality of life and its relationship to motor and cognitive functions in Parkinson's disease after deep brain stimulation. J Neurol Sci. 2017;379:18-21.

  Yamamoto T, Uchiyama T, Higuchi Y, Asahina M, Hirano S, Yamanaka Y, Weibing L, Kuwabara S.

• 47. Modern management for brain metastasis patients using stereotactic radiosurgery: literature review and the authors' gamma knife treatment experiences. Cancer Manag Res. 2018;10:1889-1899.

  Higuchi Y, Yamamoto M, Serizawa T, Aiyama H, Sato Y, Barfod BE.

• 48. Postoperative Cerebral Ischemia Due to Hypotension in Moyamoya Patient with Autonomic Dysfunction. World Neurosurg 2018; 109, 204-208.

  Machida T, Higuchi Y, Nakano S, Ishige S, Shimada J, Honma K.

• 49. Urinary symptoms are correlated with quality of life after deep brain stimulation in Parkinson's disease. Brain Behav. 2018;8(12):e01164.

  Yamamoto T, Uchiyama T, Asahina M, Yamanaka Y, Hirano S, Higuchi Y, Kuwabara S.

• 50. Stereotactic radiosurgery in elderly patients with brain metastases: comparison with non-elderly patients using database of a multi-institutional prospective observational study (JLGK0901-Elderly). J Neurooncol. 2019;144(2):393-402.

  Higuchi Y, Yamamoto M, Serizawa T, Sato Y, Shuto T, Akabane A, Jokura H, Yomo S, Nagano O, Kawagishi J, Yamanaka K, Aoyama H.

• 51. Comparison of treatment results between 3- and 2-stage Gamma Knife radiosurgery for large brain metastases: a retrospective multi-institutional study. J Neurosurg. 2019;131(1):227-237.

  Serizawa T, Higuchi Y, Yamamoto M, Matsunaga S, Nagano O, Sato Y, Aoyagi K, Yomo S, Koiso T, Hasegawa T, Nakazaki K, Moriki A, Kondoh T, Nagatomo Y, Okamoto H, Kohda Y, Kawai H, Shidoh S, Shibazaki T, Onoue S, Kenai H, Inoue A, Mori H.

• 52. Function-Preserving Multimodal Treatment for Jugular Foramen Meningiomas. J Neurol Surg B Skull Base. 2019;80(3):239-243.

  Ito S, Saegusa T, Ozawa Y, Higuchi Y, Iwadate Y, Serizawa T, Nagano O, Kageyama Y, Yamakami I.

• 53. Sagittal splitting of the temporalis muscle for encephalo-myo-synangiosis to prevent ischemic complications due to a swollen temporalis muscle without inhibiting collateral developments in patients with moyamoya disease. J Neurosurg 130, 2019; 1957-1964.

  Machida T, Higuchi Y, Nakano S, Izumi M, Ishige S, Fujikawa A, Akaogi Y, Shimada J, Ono J.

• 54. Eighty percent survival rate at 15 years for 1p/19q co-deleted oligodendroglioma treated with upfront chemotherapy irrespective of tumor grade. J Neurooncol. 2019;141(1):205-211.

  Iwadate Y, Matsutani T, Hara A, Hirono S, Ikegami S, Kobayashi M, Ito D, Kawauchi D, Horiguchi K, Tamiya A, Higuchi Y.

• 55. Local tumor progression treated with Gamma Knife radiosurgery: differences between patients with 2-4 versus 5-10 brain metastases based on an update of a multi-institutional prospective observational study (JLGK0901). J Neurosurg. 2019:1-10.

  Serizawa T, Yamamoto M, Higuchi Y, Sato Y, Shuto T, Akabane A, Jokura H, Yomo S, Nagano O, Kawagishi J, Yamanaka K.

• 56. Predictive potential of preoperative electroencephalogram for neuropsychological change following subthalamic nucleus deep brain stimulation in Parkinson's disease. Acta Neurochir (Wien). 2019;161(10):2049-2058.

  Yakufujiang M, Higuchi Y, Aoyagi K, Yamamoto T, Abe M, Okahara Y, Izumi M, Nagano O, Yamanaka Y, Hirano S, Shiina A, Murata A, Iwadate Y.

• 57. Challenging Anterior Inferior Cerebellar Artery in Retrosigmoid Vestibular Schwannoma Removal. World Neurosurg. 2019;121:e370-e378.

  Yamakami I, Kubota S, Higuchi Y, Ito S.

• 58. Unilateral Occipital Transtentorial Approach with Multimodal Assistance for Resection of Large Supracerebellar Hemangioblastomas: Preliminary Experience of 2 Cases. World Neurosurg. 2019;129:e733-e740.

  Kawauchi D, Higuchi Y, Ikegami S, Adachi A, Ozaki K, Suda I, Kobayashi E, Iwadate Y.

• 59. Impact of breast cancer subtype on clinical outcomes after Gamma Knife radiosurgery for brain metastases from breast cancer: a multi-institutional retrospective study (JLGK1702). Breast Cancer Res Treat. 2020;184(1):149-159.

  Aoyagi K, Higuchi Y, Matsunaga S, Serizawa T, Yomo S, Aiyama H, Nagano O, Kondoh T, Kenai H, Shuto T, Kawagishi J, Jokura H, Sato S, Nakazaki K, Nakaya K, Hasegawa T, Kawashima M, Kawai H, Yamanaka K, Nagatomo Y, Yamamoto M, Sato Y, Aoyagi T, Matsutani T, Iwadate Y.

• 60. Decline in drawing ability and cerebral perfusion in Parkinson's disease patients after subthalamic nucleus deep brain stimulation surgery. Parkinsonism Relat Disord. 2020;70:60-66.

  Furukawa S, Hirano S, Yamamoto T, Asahina M, Uchiyama T, Yamanaka Y, Nakano Y, Ishikawa A, Kojima K, Abe M, Uji Y, Higuchi Y, Horikoshi T, Uno T, Kuwabara S.

• 61. Comparison of two-stage Gamma Knife radiosurgery outcomes for large brain metastases among primary cancers. J Neurooncol. 2020;147(1):237-246.

  Ito D, Aoyagi K, Nagano O, Serizawa T, Iwadate Y, Higuchi Y.

• 62. Evaluation of First-line Radiosurgery vs Whole-Brain Radiotherapy for Small Cell Lung Cancer Brain Metastases: The FIRE-SCLC Cohort Study. JAMA Oncol. 2020;6(7):1028-1037.

  Rusthoven CG, Yamamoto M, Bernhardt D, Smith DE, Gao D, Serizawa T, Yomo S, Aiyama H, Higuchi Y, Shuto T, Akabane A, Sato Y, Niranjan A, Faramand AM, Lunsford LD, McInerney J, Tuanquin LC, Zacharia BE, Chiang V, Singh C, Yu JB, Braunstein S, Mathieu D, Touchette CJ, Lee CC, Yang HC, Aizer AA, Cagney DN, Chan MD, Kondziolka D, Bernstein K, Silverman JS, Grills IS, Siddiqui ZA, Yuan JC, Sheehan JP, Cordeiro D, Nosaki K, Seto T, Deibert CP, Verma V, Day S, Halasz LM, Warnick RE, Trifiletti DM, Palmer JD, Attia A, Li B, Cifarelli CP, Brown PD, Vargo JA, Combs SE, Kessel KA, Rieken S, Patel S, Guckenberger M, Andratschke N, Kavanagh BD, Robin TP.

• 63. Three-institution study on applicability of initial brain metastasis velocity for breast cancer brain metastasis patients undergoing stereotactic radiosurgery. J Neurooncol. 2020;147(1):177-184.

  Yamamoto M, Serizawa T, Nagano O, Aoyagi K, Higuchi Y, Sato Y, Kasuya H, Barfod BE.

• 64. Stereotactic radiosurgery for brain metastases: A retrospective cohort study comparing treatment results between two lung cancer patient age groups, 75 years or older vs 65-74 years. Lung Cancer. 2020;149:103-112.

  Yamamoto M, Serizawa T, Sato Y, Higuchi Y, Kasuya H, Barfod BE.

• 65. Predicting Potential of Rapid Tumor Growth in Small to Medium Vestibular Schwannomas on the Basis of Sway Assessed Using Posturography. World Neurosurg. 2021;148:e406-e414. doi: 10.1016/j.wneu.2020.12.175

  Higuchi Y, Ikegami S, Horiguchi K, Aoyagi K, Nagano O, Serizawa T, Tajima Y, Hanazawa T, Yamakami I, Iwadate Y.

• 66. Neuropsychiatric Symptoms in Parkinson's Disease After Subthalamic Nucleus Deep Brain Stimulation. Front Neurol. 2021;12:656041. doi: 10.3389/fneur.2021.656041

  Liu W, Yamamoto T, Yamanaka Y, Asahina M, Uchiyama T, Hirano S, Shimizu K, Higuchi Y, Kuwabara S.

• 67. Predicting Neurocognitive Change after Bilateral Deep Brain Stimulation of Subthalamic Nucleus for Parkinson's Disease. World Neurosurg. 2021;147:e428-e436.

  Yakufujiang M, Higuchi Y, Aoyagi K, Yamamoto T, Sakurai T, Abe M, Okahara Y, Izumi M, Nagano O, Yamanaka Y, Hirano S, Shiina A, Murata A, Iwadate Y.

• 68. Stereotactic Radiosurgery Results for Patients with 5-10 versus 11-20 Brain Metastases: A Retrospective Cohort Study Combining 2 Databases Totaling 2319 Patients. World Neurosurg. 2021;146:e479-e491.

  Yamamoto M, Serizawa T, Sato Y, Higuchi Y, Kasuya H.

• 69. Growth potential of small residual tumors after vestibular schwannoma surgery: comparison between remnants and the natural history of small tumors. J Neurosurg. 2022:1-9. doi: 10.3171/2022.10.JNS22680

  Higuchi Y, Nakano S, Aoyagi K, Origuchi S, Horiguchi K, Serizawa T, Yamakami I, Iwadate Y.

• 70. Utility of movement disorder society-unified Parkinson's disease rating scale for evaluating effect of subthalamic nucleus deep brain stimulation. Front Neurol. 2022;13:1042033. doi: 10.3389/fneur.2022.1042033

  Yamamoto T, Yamanaka Y, Hirano S, Higuchi Y, Kuwabara S.

• 71. The role of optimal cut-off diagnosis in 11C-methionine PET for differentiation of intracranial brain tumor from non-neoplastic lesions before treatment. Clinical Imaging, 2022; 92:124-130. doi: 10.1016/j.clinimag.2022.10.007

  Yamaki T, Higuchi Y, Yokotad H, Iwada Y, Matsutani T, Hirono S, Sasaki H, Sasao R, Toda M, Onodera S, Oka N, Kobayashi S.

• 72. Long-term outcomes of hearing preservation after retrosigmoid removal of large vestibular schwannoma. Neurology India, 2023, 71: 255-9. Doi: 10.4103/0028-3886.375385

  Yamakami I, Kubota S, Higuchi Y, Serizawa T.

• 73. Comparison of First-Line Radiosurgery for Small-Cell and Non-Small Cell Lung Cancer Brain Metastases (Cross-FIRE). JNCI-J Natl Cancer Inst.2023; 115: 926-936. doi: 10.1093/jnci/djad073

  Rusthoven CG, Staley AW, Gao D, Yomo S, Bernhardt D, Wandrey N, El Shafie R, Kraemer A, Padilla O, Chiang V, Faramand AM, Palmer JD, Zacharia BE, Wegner RE, Hattangadi-Gluth JA, Levy A, Bernstein K, Mathieu D, Cagney DN, Chan MD, Grills IS, Braunstein S, Lee C-c, Sheehan JP, Kluwe C, Patel S, Halasz LM, Andratschke N, Deibert CP, Verma V, Trifiletti DM, Cifarelli CP, Debus J, Combs SE, Sato Y, Higuchi Y, Aoyagi K, Brown PD, Alami V, Niranjan A, Lunsford LD, Kondziolka D, Camidge DR, Kavanagh BD, Robin TP, Serizawa T and Yamamoto M.

• 74. The safety and feasibility of transcranial direct current stimulation for patients with chronic severe traumatic brain injury in Japan, a phase I study. Brain Disord 2024; 13: 100123

  Yamaki T, Yakufujiang M, Oka N, Ito D, Odaki M, Kobayashi S, Higuchi Y.

• 75. Language Lateralization by Passive Auditory fMRI in Presurgical Assessment for Temporal Lobe Epilepsy: A Single-Center Retrospective Study: J Clin Med 2024;13: 1706

  Okahara Y, Aoyagi K, Iwasa H, Higuchi Y.

• 76. Validity test of small cell lung cancer (SCLC) graded prognostic assessment and proposal of a new index for patients with brain metastases from SCLC. Clinical & Translational Radiation Oncology 2024

  Yamamoto M, Serizawa T, Sato Y, Higuchi Y, Kikuchi Y, Sato S.

• 77. Subthalamic nucleus local field potential stability in patients with Parkinson's disease. Neurobiology of Disease 2024; 199

  Fasano A, Mure H, Oyama G, Murase N, Witt T, Higuchi Y, Singer A, Sannelli C, Morelli N, on behalf of the DBS PSR Study Group.

• 78. 椎骨脳底動脈系頭蓋内動脈解離の全国調査(最終報告)第３報 ─虚血発症─. 脳卒中の外科 2015;43:257-261. doi: 10.2335/scs.43.257

  樋口佳則, 小野純一, 田島洋佑, 町田利生, 佐伯直勝, 山浦晶

• 79. 椎骨脳底動脈系頭蓋内動脈解離の全国調査(最終報告)第1報─概要について─. 脳卒中の外科 2015;43:245-251. doi: 10.2335/scs.43.245

  小野純一, 樋口佳則, 田島洋佑, 町田利生, 佐伯直勝, 山浦晶

• 80. 椎骨脳底動脈系頭蓋内動脈解離の全国調査(最終報告)第2報 ─出血発症─ 脳卒中の外科 2015;43:252-256. doi: 10.2335/scs.43.252

  田島洋佑, 小野純一, 樋口佳則, 町田利生, 佐伯直勝, 山浦晶

• 81. 椎骨脳底動脈系頭蓋内動脈解離の保存的治療例における画像所見の経時的変化と長期的転帰　脳卒中の外科2015;43:118-124. doi: 10.2335/scs.43.118

  小野純一，樋口佳則，町田利生，松田信二，石毛 聡，永野 修，田島 洋佑

• 82. 片側顔面けいれんに対する微小血管減圧術　脳神経外科ジャーナル 2017; 263-272. doi: 10.7887/jcns.26.263

  樋口佳則，廣野誠一郎，堀口健太郎，山上岩男，岩立康男

• 83. 不随意運動症に対する脳深部刺激療法　脳神経外科ジャーナル 2019; 28:342-351. doi: 10.7887/jcns.28.342

  樋口佳則，青柳京子，和泉允基，Maidinamu Yakufujiang，岡原陽二，永野修，岩立康男．

• 84. 聴神経腫瘍の包括的理解と最適な治療選択にむけて　脳神経外科ジャーナル 2021; 30:29-40. doi: 10.7887/jcns.30.29

  樋口佳則，山上岩男，芹澤徹，岩立康男．

著書

• 樋口佳則，佐伯直勝. 額・顔面異常と中枢疾患. 特集・耳鼻咽喉科医が見落としてはいけない中枢疾患: 中枢疾患が引き起こす耳鼻科領域の症状 ENTONI (2014); 166: 35-39

• 樋口佳則. 運動障害疾患に対するガンマナイフ治療. 脳神経外科速報 (2014) ; 24: 652-657

• 樋口佳則，岡原陽二，和泉允基，青柳京子　脊髄障害性疼痛の脊髄刺激療法　Journal of Clinical Rehabilitation 2016;25:564-569.

• 樋口佳則，佐伯直勝 (2013) 頭部外傷の合併症: 外傷後の髄膜炎・硬膜外膿瘍・脳膿瘍．今日の神経疾患治療指針第２版， 水澤 英洋, 梶 龍兒, 吉良 潤一, 齊藤 延人, 神田 隆, 鈴木 則編　医学書院，東京，2013:575-577

• Higuchi Y. Stereotactic radiosurgery for movement disorders. In Principales and practice of stereotactic radiosurgery, ed. Chin LS and Regine WF: Springer-Verlag New York, 2015:671-680.

• Higuchi Y. Gamma knife radiosurgery for movement disorders. In Atlas of Neurosurgical techniques: Brain 2nd edition, ed. Sekhar LN and Fessler GF ed. Thieme New York, 2016:780-784

• Serizawa T, Higuchi Y. Radiosurgery for malignant intracranial tumors in Youmans and Winn Neurological Surgery, 4-Volume Set 7th Edition: 2201-2208

• 樋口佳則（分担執筆）不随意運動．機能的脳神経外科　診療ガイドブック，三國信啓編 MEDICAL VIEW，東京，2018: 88-104

• 樋口佳則，岡原陽二，青柳京子（分担執筆）　疾患・術式別　脳神経外科手術合併症の回避・対処法156（脳神経外科速報　2019年増刊），吉村紳一（監），吉本幸司（編），大阪，2019

その他

• 【受賞】2006年　千葉大学脳神経外科医会研究会 山浦賞（脳腫瘍に関する研究）