野村 伊知郎 のむら いちろう 先生

来歴等

略歴

1986年　高知医科大学医学部卒業
1991年　高知医科大学大学院卒業 医学博士取得
1991年　室戸中央病院小児科医長
1997年　国立小児病院アレルギー科レジデント
2000年　National Jewish Medical and Research Center, Research Scholar
2003年　国立成育医療研究センターアレルギー科医員
2007年　国立神奈川病院　小児科医長
2010年　現職

論文

1. Morita H, Suzuki H, Orihara K, Motomura K, Matsuda A, Ohya Y, Saito H, Nomura I, Matsumoto K. Food protein-induced enterocolitis syndromes with and without bloody stool have distinct clinicopathologic features. J Allergy Clin Immunol 2017.
2. Shoda T, Matsuda A, Nomura I, Okada N, Orihara K, Mikami H, Ishimura N, Ishihara S, Matsumoto K, Kinoshita Y. Eosinophilic esophagitis versus proton pump inhibitor-responsive esophageal eosinophilia: Transcriptome analysis. J Allergy Clin Immunol 2017; 139:2010-3.e4.
3. Sato M, Shoda T, Shimizu H, Orihara K, Futamura K, Matsuda A, Yamada Y, Irie R, Yoshioka T, Shimizu T, Ohya Y, Nomura I, Matsumoto K, Arai K. Gene Expression Patterns in Distinct Endoscopic Findings for Eosinophilic Gastritis in Children. J Allergy Clin Immunol Pract 2017.
4. Mitsui M, Shoda T, Natsume O, Nomura I, Narita M, Fukuda A, Sakamoto S, Kasahara M, Ohya Y. Factors Associated with Development of Food Allergy in Young Children after Liver Transplantation: A Retrospective Analysis of 10 Years' Experience. J Allergy Clin Immunol Pract 2017.
5. Shoda T, Matsuda A, Arai K, Shimizu H, Morita H, Orihara K, Okada N, Narita M, Ohya Y, Saito H, Matsumoto K, Nomura I. Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels. J Allergy Clin Immunol 2016; 138:299-303.
6. Shoda T, Morita H, Nomura I, Ishimura N, Ishihara S, Matsuda A, Matsumoto K, Kinoshita Y. Comparison of gene expression profiles in eosinophilic esophagitis (EoE) between Japan and Western countries. Allergol Int 2015; 64:260-5.
7. Nowak-Wegrzyn A, Chehade M, Groetch ME, Spergel JM, Wood RA, Allen K, Atkins D, Bahna S, Barad AV, Berin C, Brown Whitehorn T, Burks AW, Caubet JC, Cianferoni A, Conte M, Davis C, Fiocchi A, Grimshaw K, Gupta R, Hofmeister B, Hwang JB, Katz Y, Konstantinou GN, Leonard SA, Lightdale J, McGhee S, Mehr S, Sopo SM, Monti G, Muraro A, Noel SK, Nomura I, Noone S, Sampson HA, Schultz F, Sicherer SH, Thompson CC, Turner PJ, Venter C, Westcott-Chavez AA, Greenhawt M. International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 2017; 139:1111-26.e4.
8. Ito J, Fujiwara T, Kojima R, Nomura I. Racial differences in eosinophilic gastrointestinal disorders among Caucasian and Asian. Allergol Int 2015; 64:253-9.
9. Horimukai K, Hayashi K, Tsumura Y, Nomura I, Narita M, Ohya Y, Saito H, Matsumoto K. Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies. Allergy 2015; 70:334-7.
10. Morita H, Nomura I, Orihara K, Yoshida K, Akasawa A, Tachimoto H, Ohtsuka Y, Namai Y, Futamura M, Shoda T, Matsuda A, Kamemura N, Kido H, Takahashi T, Ohya Y, Saito H, Matsumoto K. Antigen-specific T-cell responses in patients with non-IgE-mediated gastrointestinal food allergy are predominantly skewed to T(H)2. J Allergy Clin Immunol 2013; 131:590-2.e1-6.
11. Morita H, Nomura I, Matsuda A, Saito H, Matsumoto K. Gastrointestinal food allergy in infants. Allergol Int 2013; 62:297-307.
12. Kojima R, Matsuda A, Nomura I, Matsubara O, Nonoyama S, Ohya Y, Saito H, Matsumoto K. Salivary cortisol response to stress in young children with atopic dermatitis. Pediatr Dermatol 2013; 30:17-22.
13. Katsunuma T, Fujisawa T, Nagao M, Akasawa A, Nomura I, Yamaoka A, Kondo H, Masuda K, Yamaguchi K, Terada A, Ikeda M, Nishioka K, Adachi Y, Kurihara K. Effects of transdermal tulobuterol in pediatric asthma patients on long-term leukotriene receptor antagonist therapy: results of a randomized, open-label, multicenter clinical trial in Japanese children aged 4-12 years. Allergol Int 2013; 62:37-43.
14. Nomura I, Morita H, Ohya Y, Saito H, Matsumoto K. Non-IgE-mediated gastrointestinal food allergies: distinct differences in clinical phenotype between Western countries and Japan. Curr Allergy Asthma Rep 2012; 12:297-303.
15. Yamada Y, Nishi A, Ebara Y, Kato M, Yamamoto H, Morita H, Nomura I, Matsumoto K, Hirato J, Hatakeyama SI, Suzuki N, Hayashi Y. Eosinophilic gastrointestinal disorders in infants: a Japanese case series. Int Arch Allergy Immunol 2011; 155 Suppl 1:40-5.
16. Nomura I, Morita H, Hosokawa S, Hoshina H, Fukuie T, Watanabe M, Ohtsuka Y, Shoda T, Terada A, Takamasu T, Arai K, Ito Y, Ohya Y, Saito H, Matsumoto K. Four distinct subtypes of non-IgE-mediated gastrointestinal food allergies in neonates and infants, distinguished by their initial symptoms. J Allergy Clin Immunol 2011; 127:685-8.e1-8.
17. Noguchi E, Sakamoto H, Hirota T, Ochiai K, Imoto Y, Sakashita M, Kurosaka F, Akasawa A, Yoshihara S, Kanno N, Yamada Y, Shimojo N, Kohno Y, Suzuki Y, Kang MJ, Kwon JW, Hong SJ, Inoue K, Goto Y, Yamashita F, Asada T, Hirose H, Saito I, Fujieda S, Hizawa N, Sakamoto T, Masuko H, Nakamura Y, Nomura I, Tamari M, Arinami T, Yoshida T, Saito H, Matsumoto K. Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. PLoS Genet 2011; 7:e1002170.
18. Fukuie T, Nomura I, Horimukai K, Manki A, Masuko I, Futamura M, Narita M, Ohzeki T, Matsumoto K, Saito H, Ohya Y. Proactive treatment appears to decrease serum immunoglobulin-E levels in patients with severe atopic dermatitis. Br J Dermatol 2010; 163:1127-9.
19. Leung DY, Boguniewicz M, Howell MD, Nomura I, Hamid QA. New insights into atopic dermatitis. J Clin Invest 2004; 113:651-7.
20. Nomura I, Goleva E, Howell MD, Hamid QA, Ong PY, Hall CF, Darst MA, Gao B, Boguniewicz M, Travers JB, Leung DY. Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J Immunol 2003; 171:3262-9.
21. Nomura I, Gao B, Boguniewicz M, Darst MA, Travers JB, Leung DY. Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis. J Allergy Clin Immunol 2003; 112:1195-202.
22. Nomura I, Katsunuma T, Tomikawa M, Shibata A, Kawahara H, Ohya Y, Abe J, Saito H, Akasawa A. Hypoproteinemia in severe childhood atopic dermatitis: a serious complication. Pediatr Allergy Immunol 2002; 13:287-94.
23. Nomura I, Katsunuma T, Matsumoto K, Iida M, Tomita H, Tomikawa M, Kawahara H, Akasawa A, Pawankar R, Saito H. Human mast cell progenitors in peripheral blood from atopic subjects with high IgE levels. Clin Exp Allergy 2001; 31:1424-31.
24. Nomura I, Tanaka K, Tomita H, Katsunuma T, Ohya Y, Ikeda N, Takeda T, Saito H, Akasawa A. Evaluation of the staphylococcal exotoxins and their specific IgE in childhood atopic dermatitis. J Allergy Clin Immunol 1999; 104:441-6.
25. 溜 雅, 野村 伊, 森田 英. 【小児科ケースカンファレンス】 呼吸器、アレルギー　新生児・乳児消化管アレルギー. 小児科診療 2017; 80:221-4.
26. 野村 伊. 【アレルギーNext Stage】 食物アレルギー　消化管アレルギー　新生児-乳児消化管アレルギー、好酸球性胃腸炎、好酸球性食道炎. 小児内科 2017; 49:89-93.
27. 野村伊知郎, 正田哲雄, 松田明生, 鈴木啓子, 折原芳波, 岡田直子, 森田英明, 成田雅美, 大矢幸弘, 斎藤博久, 松本健治. 食物アレルギー(消化管アレルギー) 新生児-乳児消化管アレルギー、クラスター3における血清中TSLP、IL33の上昇. アレルギー 2016; 65:546.
28. 野村伊知郎. 【新たな指定難病としてのアレルギー関連疾患】 好酸球性消化管疾患. 臨床免疫・アレルギー科 2016; 65:35-40.
29. 野村伊知郎. 新生児・乳児消化管アレルギーの病型分類と重症度分類　有効性と有用性 新生児-乳児消化管アレルギー、クラスター分類について. 日本小児アレルギー学会誌 2016; 30:27-32.
30. 野村伊知郎. 【免疫症候群(第2版)-その他の免疫疾患を含めて-】 アレルギー性疾患　食物アレルギー　新生児-乳児消化管アレルギー. 日本臨床 2016; 別冊:389-95.
31. 野村伊知郎. アレルギー用語解説シリーズ　新生児-乳児消化管アレルギー. アレルギー 2016; 65:77-8.
32. 野村伊知郎. 【アレルギー疾患のすべて】 アレルギー疾患各論　食物アレルギー　新生児　乳児消化管アレルギー. 日本医師会雑誌 2016; 145:S248-S50.
33. 野村伊知郎. 【消化管アレルギー】 消化管アレルギーの分類と鑑別　新生児-乳児消化管アレルギーのクラスター分類. 小児内科 2016; 48:1279-83.
34. 野村伊知郎. 新生児-乳児消化管アレルギーの診断と治療の進め方. 小児科 2016; 57:1369-75.

その他

• 【受賞】 2003 American Academy of Asthma, Allergy and Immunology, Sepracor Excellent Research Award.

• 【受賞】2011年　日本小児栄養消化器肝臓学会　優秀演題賞