水足 邦雄 みずたり くにお 先生

来歴等

略歴

1999年 横浜市立大学 医学部 卒業
2006年 慶應義塾大学 医学部 助教
2008年 博士（医学）慶應義塾大学 医学部 大学院
2009年 Department of Otology and Laryngology, Harvard Medical School, Postdoctoral Research Fellow
2014年 防衛医科大学校 耳鼻咽喉科学講座 講師

論文

• 1. Patency of Anterior Epitympanic Space and Surgical Outcomes After Endoscopic Ear Surgery for the Attic Cholesteatoma. Otol Neurotol, 42, 266-273, 2021.

  Mizutari, K., Takihata, S., Kimura, E., Inuzuka, E. & Shiotani, A.

• 2. Y-27632, a ROCK inhibitor, improved laser-induced shock wave (LISW)-induced cochlear synaptopathy in mice. Mol Brain, 14, 105, 2021.

  Koizumi, Y., Mizutari, K., Kawauchi, S., Sato, S., Shiotani, A. & Kakehata, S.

• 3. Effect of shock wave power spectrum on the inner ear pathophysiology in blast-induced hearing loss. Sci Rep, 11, 14704, 2021.

  Kimura, E., Mizutari, K., Kurioka, T., Kawauchi, S., Satoh, Y., Sato, S. & Shiotani, A.

• 4. The influence of a noisy environment on hearing impairment and tinnitus: The hearing outcomes of 50-year-old male Japan ground self-defense force personnel. Auris Nasus Larynx, 47, 931-937, 2020.

  Takihata, S., Mizutari, K., Morita, I., Matsuo, H., Nakayama, A., Shimizu, S., Ueno, M., Ito, T., Shinomiya, N. & Shiotani, A.

• 5. Tinnitus rat model generated by laser-induced shock wave; a platform for analyzing the central nervous system after tinnitus generation. Auris Nasus Larynx, 2020.

  Niwa, K., Mizutari, K., Matsui, T., Kawauchi, S., Sato, S., Shiotani, A. & Kobayashi, Y.

• 6. Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea. Front Cell Neurosci, 14, 572434, 2020.

  Koizumi, Y., Ito, T., Mizutari, K. & Kakehata, S.

• 7. Risk factors of post-tonsillectomy hemorrhage in adults. Laryngoscope Investig Otolaryngol, 5, 1056-1062, 2020.

  Inuzuka, Y., Mizutari, K., Kamide, D., Sato, M. & Shiotani, A.

• 8. Pathophysiology of the inner ear after blast injury caused by laser-induced shock wave. Sci Rep, 6, 31754, 2016.

  Niwa, K., Mizutari, K., Matsui, T., Kurioka, T., Matsunobu, T., Kawauchi, S., Satoh, Y., Sato, S., Shiotani, A. & Kobayashi, Y.

• 9. Hyaluronic acid pretreatment for Sendai virus-mediated cochlear gene transfer. Gene Ther, 23, 187-95, 2016.

  Kurioka, T., Mizutari, K., Niwa, K., Fukumori, T., Inoue, M., Hasegawa, M. & Shiotani, A.

• 10. Recovery of endocochlear potential after severe damage to lateral wall fibrocytes following acute cochlear energy failure. Neuroreport, 27, 1159-66, 2016.

  Kitao, K., Mizutari, K., Nakagawa, S., Matsunaga, T., Fukuda, S. & Fujii, M.

• 11. NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea. Sci Rep, 6, 19329, 2016.

  Honkura, Y., Matsuo, H., Murakami, S., Sakiyama, M., Mizutari, K., Shiotani, A., Yamamoto, M., Morita, I., Shinomiya, N., Kawase, T., Katori, Y. & Motohashi, H.

• 12. High prevalence of CDH23 mutations in patients with congenital high-frequency sporadic or recessively inherited hearing loss. Orphanet J Rare Dis, 10, 60, 2015.

  Mizutari, K., Mutai, H., Namba, K., Miyanaga, Y., Nakano, A., Arimoto, Y., Masuda, S., Morimoto, N., Sakamoto, H., Kaga, K. & Matsunaga, T.

• 13. Age-Related Hearing Loss and the Factors Determining Continued Usage of Hearing Aids among Elderly Community-Dwelling Residents. PLoS One, 8, e73622, 2013.

  Mizutari, K., Michikawa, T., Saito, H., Okamoto, Y., Enomoto, C., Takebayashi, T., Ogawa, K. & Nishiwaki, Y.

• 14. Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron, 77, 58-69, 2013.

  Mizutari, K., Fujioka, M., Hosoya, M., Bramhall, N., Okano, H. J., Okano, H. & Edge, A. S.

• 15. Late-phase recovery in the cochlear lateral wall following severe degeneration by acute energy failure. Brain Res, 1419, 1-11, 2011.

  Mizutari, K., Nakagawa, S., Mutai, H., Fujii, M., Ogawa, K. & Matsunaga, T.

• 16. Hearing handicap predicts the development of depressive symptoms after 3 years in older community-dwelling Japanese. J Am Geriatr Soc, 58, 93-7, 2010.

  Saito, H., Nishiwaki, Y., Michikawa, T., Kikuchi, Y., Mizutari, K., Takebayashi, T. & Ogawa, K.

• 17. Vestibular dysfunction in a Japanese patient with a mutation in the gene OPA1. J Neurol Sci, 293, 23-8, 2010.

  Mizutari, K., Matsunaga, T., Inoue, Y., Kaneko, H., Yagi, H., Namba, K., Shimizu, S., Kaga, K. & Ogawa, K.

• 18. Balance dysfunction resulting from acute inner ear energy failure is caused primarily by vestibular hair cell damage. J Neurosci Res, 88, 1262-72, 2010.

  Mizutari, K., Fujioka, M., Nakagawa, S., Fujii, M., Ogawa, K. & Matsunaga, T.

著書

• 1. Kunio Mizutari, Endoscopic Surgery for Adhesive Otitis Media. Innovations in Endoscopic Ear Surgery, Editor; Seiji Kakehata, Elsevier, 101-108, 2020.

• 2. 水足 邦雄（分担執筆）. 鼻出血, 小児救急ハンドブック, 五十嵐隆監修, 中山書店, 346-347, 2014.

• 3. 水足 邦雄（分担執筆). 中等度難聴児にふさわしい補聴器, 小児の中等度難聴ハンドブック, 加我君孝編集, 金原出版, 87-93, 2009.

特許

• 1. エッジ，アルバート 岡野 栄之 藤岡 正人 水足 邦雄 公表特許公報(A)_聴覚喪失治療　出願番号2015527398、2015年

受賞

• 1. 2013年 International Otopathology Society, Schuknecht Prize

• 2. 2013年 慶應義塾大学医学部 三四会奨励賞

• 3. 2013年 International Otology Society (Politzer Society), Politzer Prize

• 4. 2018年 日本耳科学会賞