山上 裕機 やまうえ ひろき 先生

来歴等

略歴

1981年 和歌山県立医科大学 医学部 卒業
1981年 和歌山県立医科大学附属病院 診療医
1985年 和歌山県立医科大学 消化器外科 助手
1991年 和歌山県立医科大学 消化器外科 講師
1992年 アメリカNIHの国立がん研究所（NCI）にてVisiting Associateとして癌免疫遺伝子治療の基礎研究に従事
1994年 和歌山県立医科大学 外科学第2講座 講師（大学の機構改革で講座名変更）
2001年 和歌山県立医科大学 外科学第2講座 教授
2006年 和歌山県立医科大学附属病院 副院長 兼務
2010年 和歌山県立医科大学 副学長 兼務
2014年 和歌山県立医科大学 医学部長 兼務
2017年 和歌山県立医科大学附属病院 病院長 兼務
2024年 昭和大学 消化器・一般外科 膵がん治療センター

論文

Hirono S, Kawai M, Okada K, Miyazawa M, Kitahata Y, Hayami S, Ueno M, Yamaue H; Modified Blumgart mattress suture versus conventional interrupted suture in pancreaticojejunostomy during pancreaticoduodenectomy: randomized controlled trial. Ann Surg. 269(2):243-251, 2019

Shimizu Y, Hijioka S, Hirono S, Kin T, Ohtsuka T, Kanno A, Koshita S, Hanada K, Kitano M, Inoue H, Itoi T, Ueki T, Matsuo K, Yanagisawa A, Yamaue H, Sugiyama M, Okazaki K: New Model for Predicting Malignancy in Patients With Intraductal Papillary Mucinous Neoplasm. Ann Surg. 2018 Nov 29. doi: 10.1097/SLA.0000000000003108. [Epub ahead of print] PMID: 30499803

Kawai M, Yamaue H: Reply to Letter to the Editor "Pancreatic Fistula Following Distal Pancreatectomies. It's better Not Looking for It". Ann Surg. 267(3):e51-e52, 2018

Kawai M, Yamaue H: Reply to: The Letter to the Editor "Randomized Controlled Trial of Pancreaticojejunostomy versus Stapler Closure of the Pancreatic Stump During Distal Pancreatectomy to Reduce Pancreatic Fistula". Ann Surg. 267(2):e38-e39, 2018

Wardell CP, Fujita M, Yamada T, Simbolo M, Fassan M, Karlic R, Polak P, Kim J, Hatanaka Y, Maejima K, Lawlor RT, Nakanishi Y, Mitsuhashi T, Fujimoto A, Furuta M, Ruzzenente A, Conci S, Oosawa A, Sasaki-Oku A, Nakano K, Tanaka H, Yamamoto Y, Michiaki K, Kawakami Y, Aikata H, Ueno M, Hayami S, Gotoh K, Ariizumi SI, Yamamoto M, Yamaue H, Chayama K, Miyano S, Getz G, Scarpa A, Hirano S, Nakamura T, Nakagawa H: Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations. J Hepatol. 68(5):959-969, 2018

Jang JY, Park T, Lee S, Kim Y, Lee SY, Kim SW, Kim SC, Song KB, Yamamoto M, Hatori T, Hirono S, Satoi S, Fujii T, Hirano S, Hashimoto Y, Shimizu Y, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Han HS, Yoon YS, Sho M, Nagano H, Honda G, Kim SG, Yu HC, Chung JC, Nagakawa Y, Seo HI, Yamaue H: Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients With Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas. Ann Surg. 266(6):1062-1068, 2017

Ojima T, Nakamori M, Nakamura M, Katsuda M, Hayata K, Kato T, Kitadani J, Tabata H, Takeuchi A, Yamaue H: Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer. Br J Surg. 104(8):1003-1009, 2017

Furuta M, Ueno M, Fujimoto A, Hayami S, Yasukawa S, Kojima F, Arihiro K, Kawakami Y, Wardell CP, Shiraishi Y, Tanaka H, Nakano K, Maejima K, Sasaki-Oku A, Tokunaga N, Boroevich KA, Abe T, Aikata H, Ohdan H, Goto K, Kubo M, Tsunoda T, Miyano S, Chayama K, Yamaue H, Nakagawa H: Whole genome sequencing discriminate hepatocellular carcinoma with intrahepatic metastasis from multicentric tumors. J Hepatol. 66(2):363-373, 2017

Kawai M, Hirono S, Okada K, Sho M, Nakajima Y, Eguchi H, Nagano H, Ikoma H, Morimura R, Takeda Y, Nakahira S, Suzumura K, Fujimoto J, Yamaue H: Randomized Controlled Trial of Pancreaticojejunostomy versus Stapler Closure of the Pancreatic Stump During Distal Pancreatectomy to Reduce Pancreatic Fistula. Ann Surg. 264(1):180-7, 2016

Nakamura M, Nakamori M, Ojima T, Iwahashi M, Horiuchi T, Kobayashi Y, Yamade N, Shimada K, Oka M, Yamaue H: Randomized clinical trial comparing long-term quality of life for Billroth I versus Roux-en-Y reconstruction after distal gastrectomy for gastric cancer. Br J Surg. 103(4):337-47, 2016

Matsuda K, Hotta T, Takifuji K, Yokoyama S, Oku Y, Watanabe T, Mitani Y, Ieda J, Mizumoto Y, Yamaue H: Randomized clinical trial of defaecatory function after anterior resection for rectal cancer with high versus low ligation of the inferior mesenteric artery. Br J Surg 102(5):501-8, 2015

Ueno M, Hayami S, Shigekawa Y, Kawai M, Hirono S, Okada KI, Tamai H, Shingaki N, Mori Y, Ichinose M, Yamaue H: Prognostic impact of surgery and radiofrequency ablation on single nodular HCC ≤ 5 cm: cohort study based on serum HCC markers. J Hepatol. 63(6):1352-9, 2015

Tani M, Kawai M, Hirono S, Okada K, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H: Randomized clinical trial of isolated Roux-en-Y versus conventional reconstruction after pancreaticoduodenectomy. Br J Surg 101(9):1084-91, 2014

Hirono S, Tani M, Kawai M, Okada K, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H：The carcinoembryonic antigen level in pancreatic juice and mural nodule size are predictors of malignancy for branch duct type intraductal papillary mucinous neoplasms of the pancreas.　Ann Surg. 255(3):517-22, 2012

Kiriyama S, Uchiyama K, Ueno M, Ozawa S, Hayami S, Tani M, Yamaue H：Triple positive tumor markers for hepatocellular carcinoma are useful predictors of poor survival.　Ann Surg. 254(6):984-91, 2011

Kawai M, Tani M, Hirono S, Miyazawa M, Shimizu A, Uchiyama K, Yamaue H：Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy.　Ann Surg. 253(3):495-501, 2011

Kawai M, Tani M, Terasawa H, Ina S, Hirono S, Nishioka R, Miyazawa M, Uchiyama K, Yamaue H：Early removal of prophylactic drains reduces the risk of intra-abdominal infections in patients with pancreatic head resection: prospective study for 104 consecutive patients.　Ann Surg. 244(1):1-7, 2006

Tani M, Terasawa H, Kawai M, Ina S, Hirono S, Uchiyama K, Yamaue H：Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial.　Ann Surg. 243(3):316-20, 2006

Uchiyama K, Onishi H, Tani M, Kinoshita H, Kawai M, Ueno M, Yamaue H：Long-term prognosis after treatment of patients with choledocholithiasis.　Ann Surg. 238(1):97-102, 2003

PubMed英文論文　469編（2019年7月10日現在）

著書

Miyazawa M, Hirono S, Yamaue H: Staging and Determination of Resectability of Pancreatic Cancer.　Pancreatic Cancer, p133-138. ISBN 978-3-662-47181-4 (eBook)，DOI 10.1007/978-3-662-47181-4_10:133-8，Springer, 2017

Hirono S, Yamaue H: Mesenteric Approach for Pancreaticoduodenectomy. Pancreatic Cancer, p201-206. ISBN 978-3-662-47181-4 (eBook)，DOI 10.1007/978-3-662-47181-4_17:201-6, Springer, 2017

Kawai M, Yamaue H: Drain Management After Pancreatectomy. Pancreatic Cancer, p377-384. ISBN 978-3-662-47181-4 (eBook)，DOI 10.1007/978-3-662-47181-4_36:377-84, Springer, 2017

Kawai M, Yamaue H: Pylorus-Resecting Pancreaticoduodenectomy.　Innovation of Diagnosis and Treatment for Pancreatic Cancer, p85-94. ISBN 978-981-10-2486-3 (eBook)，DOI 10.1007/978-981-10-2486-3_7:85-94, Springer, 2017

Okada K, Yamaue H: Indications and Pitfalls of the Modified Distal Pancreatectomy with Celiac Axis En Bloc Resection for Pancreatic Cancer. Innovation of Diagnosis and Treatment for Pancreatic Cancer, p189-209. ISBN 978-981-10-2486-3 (eBook)，DOI 10.1007/978-981-10-2486-3_14:189-210, Springer, 2017

その他

• 【受賞】優秀演題賞受賞（第１回国際胃癌学会，京都）, 1995

• 【受賞】財団法人藤井節郎記念平成22年度大阪基礎医学研究奨励会, 2010

• 【受賞】公益法人小林がん学術振興会第5回革新的研究助成, 2011

• 【受賞】The Pin-Wen Lin Award 2017（The 10th pancreatic cancer international conference）, 2017

• 【受賞】平成30年度日本外科学会臨床研究助成, 2018