市川 靖史 いちかわ やすし 先生

来歴等

略歴

1986年　北海道大学医学部卒業
1986年　沖縄県立中部病院 初期研修開始
1988年　横浜市立大学医学部附属病院第2外科 常勤特別職診療医
1993年　横浜市立大学医学部第二外科 助手
2002年　横浜市立大学医学部第二外科 講師
2005年　横浜市立大学臨床腫瘍・乳腺外科 臨床部長
2007年　横浜市立大学医学部　臨床腫瘍科学 准教授
2014年　横浜市立大学大学院医学研究科 がん総合医科学講座 主任教授

論文

Ishikawa T, Mitsuhashi M, Ichikawa Y, Tarnawski A. (3/4) Epidermal growth factor induces biphasic activation of ornithine decarboxylase in human stomach-derived KATO-III cells. Life Sci. 1994;54(18):1329-34.
Ichikawa Y, Tarnawski A, Sarfeh IJ, Ishikawa T, Shimada H. (1/5) Distorted microangioarchitecture and impaired angiogenesis in gastric mucosa of portal hypertensive rats. Gastroenterology. 1994 Mar;106(3):702-8.
Ichikawa Y, Mitsuhashi M, Ishikawa T, Wyle F, Chang K, Fujiwara Y, Arakawa T, Shimada H, Tarnawski A. (1/9) Laboratory diagnosis of Helicobacter pylori infection by polymerase chain reaction. Res Commun Mol Pathol Pharmacol. 1996, Jan;91(1):117-28.
Ishikawa T, Ichikawa Y, Mitsuhashi M, Momiyama N, Chishima T, Tanaka K, Yamaoka H, Miyazakic K, Nagashima Y, Akitaya T, Shimada H. (2/11) Matrilysin is associated with progression of colorectal tumor. Cancer Lett. 1996 Oct 1;107(1):5-10.
Ichikawa Y, Ishikawa T, Momiyama N, Chishima T, Hasegawa S, Yamaoka H, Yamamoto N, Okamoto T, Kawaguchi M, Shimada H. (1/10) Clinical application of a novel DNA fluorescence intercalator, pyrylium dye, for the quantification of PCR products. Scand J Clin Lab Invest. 1996 Nov;56(7):641-7.
Miura Y, Ichikawa Y, Ishikawa T, Ogura M, de Fries R, Shimada H, Mitsuhashi M. (2/7) Fluorometric determination of total mRNA with oligo(dT) immobilized on microtiter plates. Clin Chem. 1996 Nov;42(11):1758-64.
Ishikawa T, Ichikawa Y, Miura Y, Momiyama M, Keller C, Koo K, Akitaya T, Shimada H, Mitsuhashi M. (2/9) Construction of cDNA bank from biopsy specimens for multiple gene analysis of cancer. Clin Chem. 1997 May;43(5):764-70.
Nagashima Y, Hasegawa S, Koshikawa N, Taki A, Ichikawa Y, Kitamura H, Misugi K, Kihira Y, Matuo Y, Yasumitsu H, Miyazaki K. (5/11) Expression of matrilysin in vascular endothelial cells adjacent to matrilysin-producing tumors. Int J Cancer.1997 Jul 29;72(3):441-5.
Takeuchi N, Ichikawa Y, Ishikawa T, Momiyama N, Hasegawa S, Nagashima Y, Miyazaki K, Koshikawa N, Mitsuhashi M, Shimada H.(2/10) Matrilysin gene expression in sporadic and familial colorectal adenomas. Mol Carcinog. 1997 Aug;19(4):225-9.
Ishikawa T, Ichikawa Y, Tarnawski A, Fujiwara Y, Fukuda T, Arakawa T, Mitsuhashi M, Shimada H. (2/8) Indomethacin interferes with EGF-induced activation of ornithine decarboxylase in gastric cancer cells. Digestion. 1998;59(1):47-52.
Ichikawa Y, Ishikawa T, Momiyama N, Yamaguchi S, Masui H, Hasegawa S, Chishima T, Takimoto A, Kitamura H, Akitaya T, Hosokawa T, Mitsuhashi M, Shimada H. (1/13) Detection of regional lymph node metastases in colon cancer by using RT-PCR for matrix metalloproteinase 7, matrilysin. Clin Exp Metastasis. 1998 Jan;16(1):3-8.
Momiyama N, Koshikawa N, Ishikawa T, Ichikawa Y, Hasegawa S, Nagashima Y, Mitsuhashi M, Miyazaki K, Shimada H.(4/9) Inhibitory effect of matrilysin antisense oligonucleotides on human colon cancer cell invasion in vitro. Mol Carcinog. 1998 May;22(1):57-63.
Hasegawa S, Koshikawa N, Momiyama N, Moriyama K, Ichikawa Y, Ishikawa T, Mitsuhashi M, Shimada H, Miyazaki K.(5/9) Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model. Int J Cancer. 1998 Jun 10;76(6):812-6.
Miura Y, Ichikawa Y, Ishikawa T, Sekido H, Nakano A, Mitsuhashi M, Shimada H. (2/7) 　The elevated mRNA content as a potential indicator of precancerous states of the gallbladder mucosa in patients with pancreaticobiliary maljunction. Oncol Rep. 1998 Jul-Aug;5(4):845-51.
Takabe K, Ohki S, Kunihiro O, Sakashita T, Endo I, Ichikawa Y, Sekido H, Amano T, Nakatani Y, Suzuki K, Shimada H. (6/11) Anisakidosis: a cause of intestinal obstruction from eating sushi. Am J Gastroenterol. 1998 Jul;93(7):1172-3.
Akiyama H, Yamaoka H, Tanaka K, Ishikawa T, Ichikawa Y, Wakasugi J, Nagashima Y, Shimada H. (5/8) Continuous hyperthermic peritoneal perfusion for peritoneal dissemination of gastric cancer. Hepatogastroenterology. 1998 Nov- Dec ;45(24):2079-86.
Miyazaki K, Koshikawa N, Hasegawa S, Momiyama N, Nagashima Y, Moriyama K,Ichikawa Y, Ishikawa T, Mitsuhashi M, Shimada H. (7/10) Matrilysin as a target for chemotherapy for colon cancer: use of antisense oligonucleotides as antimetastatic agents. Cancer Chemother Pharmacol. 1999;43 Suppl:S52-5.
Tanaka K, Togo S, Nanko M, Ishikawa T, Ichikawa Y, Yamaoka H, Shimada H.(5/7)
Sialyl Lewis X expression in vascular permeating lesions as a factor for predicting colorectal cancer metastasis. Hepatogastroenterology. 1999 Mar-Apr;46(26):875-82.
Kameda K, Shimada H, Ishikawa T, Takimoto A, Momiyama N, Hasegawa S, Misuta K, Nakano A, Nagashima Y, Ichikawa Y. (10/10) Expression of highly polysialylated neural cell adhesion molecule in pancreatic cancer neural invasive lesion. Cancer Lett. 1999 Apr 1;137(2):201-7.
Ishikawa T, Ikeda I, Momiyama N, Yamaoka H, Ishiyama A, Chishima T, Ichikawa Y, Kitamura H, Shuin T, Shimada H. (7/10) Genetic instability did not lead to p53 mutations in an extremely early-onset breast cancer in a cancer-prone family. Jpn
J Clin Oncol. 1999 Jul;29(7):332-5.
Takabe K, Lebrun JJ, Nagashima Y, Ichikawa Y, Mitsuhashi M, Momiyama N, Ishikawa T, Shimada H, Vale WW. (4/9) Interruption of activin A autocrine regulation by antisense oligodeoxynucleotides accelerates liver tumor cell proliferation. Endocrinology. 1999 Jul;140(7):3125-32.
Ishikawa T, Kamiyama M, Hisatomi H, Ichikawa Y, Momiyama N, Hamaguchi Y, Hasegawa S, Narita T, Shimada H. (4/9) Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells. Cancer Lett. 1999 Jul 1;141(1-2):187-94.
Miyamoto H, Miyagi Y, Ishikawa T, Ichikawa Y, Hosaka M, Kubota Y. (4/6) DNA polymerase beta gene mutation in human breast cancer. Int J Cancer. 1999 Nov 26;83(5):708-9.
Tarnawski A, Arakawa T, Sekhon S, Ichikawa Y, Szabo I, Sarfeh IJ. (4/6) Isolation of morphologically and functionally intact gastric mucosal microvessels rapid communication. J Physiol Pharmacol. 2000 Mar;51(1):167-75.
Ichikawa Y, Koshikawa N, Hasegawa S, Ishikawa T, Momiyama N, Kunizaki C, Takahashi M, Moriwaki Y, Akiyama H, Yamaoka H, Yanoma S, Tsuburaya A, Nagashima Y, Shimada H, Miyazaki K. (1/15) Marked increase of trypsin(ogen) in serum of linitis plastica (gastric cancer, borrmann 4) patients. Clin Cancer Res. 2000
Apr;6(4):1385-8.
Hosaka N, Ichikawa Y, Ishikawa T, Nagashima Y, Kunisaki C, Takahashi M, Moriwaki Y, Akiyama H, Yamaguchi S, Ota M, Ooki S, Ike H, Shimada H. (2/13) Correlation of immunohistochemical p53 labeling index with inhibition rate in chemosensitivity test in gastric and colon cancer. Anticancer Res. 2001 Jan-Feb;21(1A):229-35.
Ishikawa T, Kamiyama M, Tani-Ishii N, Suzuki H, Ichikawa Y, Hamaguchi Y, Momiyama N, Shimada H.(5/8) Inhibition of osteoclast differentiation and bone resorption by cathepsin K antisense oligonucleotides. Mol Carcinog. 2001 Oct;32(2):84-91.
Nishizuka I, Ichikawa Y, Ishikawa T, Kamiyama M, Hasegawa S, Momiyama N, Miyazaki K, Shimada H. (2/8) Matrilysin stimulates DNA synthesis of cultured vascular endothelial cells and induces angiogenesis in vivo. Cancer Lett. 2001 Nov 28;　173(2):175-82.
Morita T, Togo S, Kubota T, Kamimukai N, Nishizuka I, Kobayashi T, Ichikawa Y, Ishikawa T, Takahashi S, Matsuo K, Tomaru Y, Okazaki Y, Hayashizaki Y, Shimada H. (7/14) Mechanism of postoperative liver failure after excessive hepatectomy investigated using a cDNA microarray. J Hepatobiliary Pancreat Surg. 2002;9(3):352-9.
Nishizuka I, Ishikawa T, Hamaguchi Y, Kamiyama M, Ichikawa Y, Kadota K, Miki R, Tomaru Y, Mizuno Y, Tominaga N, Yano R, Goto H, Nitanda H, Togo S, Okazaki Y, Hayashizaki Y, Shimada H. (5/17) Analysis of gene expression involved in brain metastasis from breast cancer using cDNA microarray. Breast Cancer. 2002;9(1):26-32.
Ishikawa T, Hamaguchi Y, Ichikawa Y, Shimura M, Kawano N, Nakatani Y, Ohnishi H, Maegawa J, Ogino I, Shimada H. (3/10) Locally advanced mucinous carcinoma of the breast with sudden growth acceleration: a case report. Jpn J Clin Oncol. 2002 Feb;32(2):64-7.
Kamiyama M, Ichikawa Y, Ishikawa T, Chishima T, Hasegawa S, Hamaguchi Y, Nagashima Y, Miyagi Y, Mitsuhashi M, Hyndman D, Hoffman RM, Ohki S, Shimada H.(2/13) VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice. Cancer Gene Ther. 2002 Feb;9(2):197-201.
Togo S, Akiyama H, Yamaguchi S, Ichikawa Y, Ike H, Shimada H. (4/6) Clinical evaluation of granisetron as an inhibitor of nausea and vomiting induced by oral anticancer drugs. Oncol Rep. 2002 Mar-Apr;9(2):277-82.
Huo N, Ichikawa Y, Kamiyama M, Ishikawa T, Hamaguchi Y, Hasegawa S, Nagashima Y, Miyazaki K, Shimada H. (2/9) MMP-7 (matrilysin) accelerated growth of human umbilical vein endothelial cells. Cancer Lett. 2002 Mar 8;177(1):95-100.
Ike H, Shimada H, Ohki S, Togo S, Yamaguchi S, Ichikawa Y. (6/6) Results of aggressive resection of lung metastases from colorectal carcinoma detected by intensive follow-up. Dis Colon Rectum. 2002 Apr;45(4):468-73; discussion 473-5.
Ichikawa Y, Ishikawa T, Takahashi S, Hamaguchi Y, Morita T, Nishizuka I, Yamaguchi S, Endo I, Ike H, Togo S, Oki S, Shimada H, Kadota K, Nakamura S, Goto H, Nitanda H, Satomi S, Sakai T, Narita I, Gejyo F, Tomaru Y, Shimizu K, Hayashizaki Y, Okazaki Y. (1/24) Identification of genes regulating colorectal carcinogenesis by using the algorithm for diagnosing malignant state method. Biochem Biophys Res Commun. 2002 Aug 16;296(2):497-506.
Ike H, Shimada H, Togo S, Yamaguchi S, Ichikawa Y, Tanaka K. (5/6) Sequential resection of lung metastasis following partial hepatectomy for colorectal cancer. Br J Surg. 2002 Sep;89(9):1164-8.
Sakakura C, Hagiwara A, Nakanishi M, Shimomura K, Takagi T, Yasuoka R, Fujita Y, Abe T, Ichikawa Y, Takahashi S, Ishikawa T, Nishizuka I, Morita T, Shimada H, Okazaki Y, Hayashizaki Y, Yamagishi H. (9/13) Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites. Br J Cancer. 2002 Nov 4;87(10):1153-61.
Morioka D, Kubota T, Sekido H, Matsuo K, Saito S, Ichikawa Y, Endo I, Togo S, Shimada H. (6/9) Prostaglandin E1 improved the function of transplanted fatty liver in a rat reduced-size-liver transplantation model under conditions of permissible cold preservation. Liver Transpl. 2003 Jan;9(1):79-86.
Miura M, Ichikawa Y, Tanaka K, Kamiyama M, Hamaguchi Y, Ishikawa T, Yamaguchi S, Togo S, Ike H, Ooki S, Shimada H. (2/11) Real-time PCR (TaqMan PCR) quantification of carcinoembryonic antigen (CEA) mRNA in the peripheral blood of colorectal cancer patients. Anticancer Res. 2003 Mar-Apr;23(2B):1271-6.
Ike H, Shimada H, Yamaguchi S, Ichikawa Y, Fujii S, Ohki S. (4/6) Outcome of total pelvic exenteration for primary rectal cancer. Dis Colon Rectum. 2003 Apr;46(4):474-80.
Ike H, Shimada H, Ohki S, Yamaguchi S, Ichikawa Y, Fujii S. (5/6) Outcome of total pelvic exenteration for locally recurrent rectal cancer. Hepatogastroenterology. 2003 May-Jun;50(51):700-3.
Ding J, Ichikawa Y, Ishikawa T, Shimada (2/4) H. Effect of formalin on extraction of mRNA from a formalin-fixed sample: a basic investigation. Scand J Clin Lab Invest. 2004;64(3):229-35.
Ichikawa Y, Kamiyama M, Sekido H, Ishikawa T, Miura Y, Kamiya N, Morita T, Shimada H. (1/8) Telomerase activity and Bcl-2 expression in gallbladders of pancreaticobiliary maljunction patients: a preliminary study. J Hepatobiliary Pancreat Surg. 2004;11(1):34-9.
Ota M, Shimada H, Masui H, Tanaka K, Yamaguchi S, Ichikawa Y, Togo S, Ike H, Oki S. (6/9) Adjuvant hepatic arterial infusion chemotherapy after curative resection for Dukes C colorectal cancer: a pilot study. Hepatogastroenterology. 2004 Jan-Feb;51(55):124-7.
Shimizu D, Ishikawa T, Ichikawa Y, Togo S, Hayasizaki Y, Okazaki Y, Shimada (3/7) H. Current progress in the prediction of chemosensitivity for breast cancer. Breast Cancer. 2004;11(1):42-8
Togo S, Makino H, Kobayashi T, Morita T, Shimizu T, Kubota T, Ichikawa Y, Ishikawa T, Okazaki Y, Hayashizaki Y, Shimada H. (7/11) Mechanism of liver regeneration after partial hepatectomy using mouse cDNA microarray. J Hepatol. 2004 Mar;40(3):464-71.
Shimada H, Tanaka K, Masui H, Nagano Y, Matsuo K, Kijima M, Ichikawa Y, Ike H, Ooki S, Togo S. (7/10) Results of surgical treatment for multiple (> or =5 nodules)bi-lobar hepatic metastases from colorectal cancer. Langenbecks Arch Surg. 2004 Apr;389(2):114-21.
Nagano Y, Nagahori K, Yoshiro F, Hamaguchi Y, Ishikawa T, Ichikawa Y, Togo S, Okazaki Y, Hayashizaki Y, Shimada H. (6/10) Gene expression profile analysis of regenerating liver after portal vein ligation in rats by a cDNA microarray system. Liver Int. 2004 Jun;24(3):253-8.
Ueda M, Miura Y, Kunihiro O, Ishikawa T, Ichikawa Y, Endo I, Sekido H, Togo S, Shimada H. (5/9) MUC1 overexpression is the most reliable marker of invasive carcinoma in intraductal papillary-mucinous tumor (IPMT). Hepatogastroenterology. 2005 Mar-Apr;52(62):398-403.
Yamagishi S, Shimada H, Ishikawa T, Fujii S, Tanaka K, Masui H, Yamaguchi S, Ichikawa Y, Togo S, Ike H. (8/10) Expression of dihydropyrimidine dehydrogenase, thymidylate synthase, p53 and p21 in metastatic liver tumor from colorectal cancer after 5-fluorouracil-based chemotherapy. Anticancer Res. 2005 Mar-Apr;25(2B):1237-42.
Kijima M, Togo S, Ichikawa Y, Miura M, Yamagishi S, Matsuo K, Tanaka K, Masui H, Ishikawa T, Ike H, Shimada H. (3/11) Clinical significance of serum CEA protein and CEA mRNA after resection of colorectal liver metastases. Anticancer Res. 2005 Mar-Apr;25(2B):1327-32.
Matsuo K, Togo S, Sekido H, Morita T, Kamiyama M, Morioka D, Kubota T, Miura Y, Tanaka K, Ishikawa T, Ichikawa Y, Endo I, Goto H, Nitanda H, Okazaki Y, Hayashizaki Y, Shimada H. (11/17) Pharmacologic preconditioning effects: prostaglandin E1 induces heat-shock proteins immediately after ischemia/reperfusion of the mouse liver. J Gastrointest Surg. 2005 Jul-Aug;9(6):758-68.
Ishikawa T, Yoshida S, Sekido H, Morioka D, Akiyama H, Ichikawa Y, Endo I, Masunari H, Togo S, Kobayashi H, Shimada H.(6/11) Biliobiliary fistulas manifested by worsening liver function a case report. Hepatogastroenterology. 2005 Jul-Aug; 52(64): 1092-4.
Shimizu D, Ishikawa T, Ichikawa Y, Togo S, Hayasizaki Y, Okazaki Y, Danenberg PV, Shimada H. (3/8) Prediction of chemosensitivity of colorectal cancer to 5-fluorouracil by gene expression profiling with cDNA microarrays. Int J Oncol. 2005 Aug;27(2):371-6.
Ishikawa T, Momiyama N, Hamaguchi Y, Tanabe M, Tomita S, Ichikawa Y, Nakatani Y, Sasaki T, Nozawa A, Inayama Y, Inui K, Shimada H(6/11). Blue-dye technique complements four-node sampling for early breast cancer. Eur J Surg Oncol. 2005 Dec;31(10):1119-24. Epub 2005 Jul 7.
Ichikawa Y, Ishikawa T, Momiyama N, Kamiyama M, Sakurada H, Matsuyama R, Hasegawa S, Chishima T, Hamaguchi Y, Fujii S, Saito S, Kubota K, Hasegawa S, Ike H, Oki S, Shimada H.(1/16) Matrilysin (MMP-7) degrades VE-cadherin and accelerates accumulation of beta-catenin in the nucleus of human umbilical vein endothelial cells. Oncol Rep. 2006
Morioka D, Watanabe K, Makino H, Saito S, Ueda M, Kubota T, Sekido H, Matsuo K, Ichikawa Y, Endo I, Togo S, Shimada H. (9/12) Safety limit of the extent of hepatectomy for rats with moderately fatty liver: experimental study concerning living liver donor safety. J Gastroenterol Hepatol. 2006 Feb;21(2):367-73.
Matsuyama R, Togo S, Shimizu D, Momiyama N, Ishikawa T, Ichikawa Y, Endo I, Kunisaki C, Suzuki H, Hayasizaki Y, Shimada H. (6/11) Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response. Int J Cancer. 2006 Jul 15;119(2):406-13.
Kimura H, Shimada H, Ike H, Yamaguchi S, Ichikawa Y, Kikuchi M, Fujii S, Ohki S. (5/8) Colonic J-pouch decreases bowel frequency by improving the evacuation ratio. Hepatogastroenterology. 2006 Nov-Dec;53(72):854-7.
Otsuka Y, Ichikawa Y, Kunisaki C, Matsuda G, Akiyama H, Nomura M, Togo S, Hayashizaki Y, Shimada H. (2/9) Correlating purity by microdissection with gene expression in gastric cancer tissue. Scand J Clin Lab Invest. 2007;67(4):367-79.
Mori R, Ishikawa T, Ichikawa Y, Taniguchi K, Matsuyama R, Ueda M, Fujii Y, Endo I, Togo S, Danenberg PV, Shimada H. (3/11) Human equilibrative nucleoside transporter 1 is associated with the chemosensitivity of gemcitabine in human pancreatic adenocarcinoma and biliary tract carcinoma cells. Oncol Rep. 2007 May;17(5):1201-5.
Ishikawa T, Miyajima E, Sasaki T, Tanabe M, Matsumoto C, Nozawa A, Kawachi K, Fukuno Y, Takeda H, Hayashi T, Onaka S, Momiyama N, Ichikawa Y, Inui K, Shimada H. (13/15) Transcription-reverse transcription concerted reaction and minimal residual disease in axillary sentinel nodes of breast cancer. Eur J Surg Oncol. 2007 May;33(4):430-4. Epub 2006 Nov 13.
Kunisaki C, Makino H, Suwa H, Sato T, Oshima T, Nagano Y, Fujii S, Akiyama H, Nomura M, Otsuka Y, Ono HA, Kosaka T, Takagawa R, Ichikawa Y, Shimada H. (14/15) Impact of splenectomy in patients with gastric adenocarcinoma of the cardia. J Gastrointest Surg. 2007 Aug;11(8):1039-44. PubMed PMID: 17514409.
Hoshi K, Takakura H, Mitani Y, Tatsumi K, Momiyama N, Ichikawa Y, Togo S,Miyagi T, Kawai Y, Kogo Y, Kikuchi T, Kato C, Arakawa T, Uno S, Cizdziel PE, Lezhava A, Ogawa N, Hayashizaki Y, Shimada H. (5/19) Rapid detection of epidermal growth factor receptor mutations in lung cancer by the SMart-Amplification Process. Clin Cancer Res. 2007 Sep 1;13(17):4974-83.
Watanabe J, Mitani Y, Kawai Y, Kikuchi T, Kogo Y, Oguchi-Katayama A, Kanamori H, Usui K, Itoh M, Cizdziel PE, Lezhava A, Tatsumi K, Ichikawa Y, Togo S, Shimada H, Hayashizaki Y. (13/16) Use of a competitive probe in assay design for genotyping of the UGT1A1 *28 microsatellite polymorphism by the smart amplification process. Biotechniques. 2007 Oct;43(4):479-84.
Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Fujii S, Otsuka Y, Akiyama H, Ono HA, Kosaka T, Ichikawa Y, Shimada H.(11/12) Impact of palliative gastrectomy in patients with incurable advanced gastric cancer. Anticancer Res.2008 Mar-Apr;28(2B):1309-15.
Yamada M, Ichikawa Y, Yamagishi S, Momiyama N, Ota M, Fujii S, Tanaka K, Togo S, Ohki S, Shimada H. (2/10) Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. Clin Cancer Res. 2008 Apr 15;14(8):2351-6.
Kunisaki C, Makino H, Takagawa R, Yamamoto N, Nagano Y, Fujii S, Kosaka T, Ono HA, Otsuka Y, Akiyama H, Ichikawa Y, Shimada H. (11/12) Surgical outcomes in esophageal cancer patients with tumor recurrence after curative esophagectomy. J Gastrointest Surg. 2008 May;12(5):802-10.
Taniguchi K, Momiyama N, Ueda M, Matsuyama R, Mori R, Fujii Y, Ichikawa Y, Endo I, Togo S, Shimada H. (7/10) Targeting of CDC20 via small interfering RNA causes enhancement of the cytotoxicity of chemoradiation. Anticancer Res. 2008 May-Jun;28: 1559-63.
Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H. (7/14) The overexpression and altered localization of the atypical protein kinase Clambda/iota in breast cancer correlates with the pathologic type of these tumors. Hum Pathol. 2008 Jun;39(6):824-31.
Kunisaki C, Makino H, Takagawa R, Oshima T, Nagano Y, Kosaka T, Ono HA, Otsuka Y, Akiyama H, Ichikawa Y, Shimada H. (10/11) Tumor diameter as a prognostic factor in patients with gastric cancer. Ann Surg Oncol. 2008 Jul;15(7):1959-67.
Tatsumi K, Mitani Y, Watanabe J, Takakura H, Hoshi K, Kawai Y, Kikuchi T, Kogo Y, Oguchi-Katayama A, Tomaru Y, Kanamori H, Baba M, Ishidao T, Usui K, Itoh M, Cizdziel PE, Lezhava A, Ueda M, Ichikawa Y, Endo I, Togo S, Shimada H,
Hayashizaki Y. (19/23) Rapid screening assay for KRAS mutations by the modified smart amplification process. J Mol Diagn. 2008 Nov;10(6):520-6.
Takagawa R, Fujii S, Ohta M, Nagano Y, Kunisaki C, Yamagishi S, Osada S, Ichikawa Y, Shimada H. (8/9) Preoperative serum carcinoembryonic antigen level as a predictive factor of recurrence after curative resection of colorectal cancer. Ann Surg Oncol. 2008 Dec;15(12):3433-9.
Ueda M, Endo I, Nakashima M, Minami Y, Takeda K, Matsuo K, Nagano Y, Tanaka K, Ichikawa Y, Togo S, Kunisaki C, Shimada H. (9/12) Prognostic factors after resection of pancreatic cancer. World J Surg. 2009 Jan;33(1):104-10.
Nojiri K, Iwakawa M, Ichikawa Y, Imadome K, Sakai M, Nakawatari M, Ishikawa K, Ishikawa A, Togo S, Tsujii H, Shimada H, Imai T. (3/12) The proangiogenic factor ephrin-A1 is up-regulated in radioresistant murine tumor by irradiation. Exp Biol Med (Maywood). 2009 Jan;234(1):112-22.
Shimizu T, Togo S, Kumamoto T, Makino H, Morita T, Tanaka K, Kubota T, Ichikawa Y, Nagasima Y, Okazaki Y, Hayashizaki Y, Shimada H. (8/12) Gene expression during liver regeneration after partial hepatectomy in mice lacking type 1 tumor necrosis factor receptor. J Surg Res. 2009 Apr;152(2):178-88.
Fujii S, Shimada H, Yamagishi S, Ota M, Ichikawa Y, Kunisaki C, Ike H, Ohki S. (6/8) Surgical strategy for local recurrence after resection of rectal cancer. Hepatogastroenterology. 2009 May-Jun;56(91-92):667-71.
Fujii S, Shimada H, Ike H, Kunisaki C, Ohki S, Ichikawa Y, Ohta M, Yamagishi S, Osada S. (6/9) Reduction of postoperative abdominal adhesion and ileus by a bioresorbable membrane. Hepatogastroenterology. 2009 May-Jun;56(91-92):725-8.
Ishikawa T, Shimizu S, Katayama K, Chishima T, Hamaguchi Y, Doi T, Tanabe M, Kasahara A, Yamaguchi N, Narui K, Ohta I, Matsumoto C, Shimizu D, Kito A, Suda T, Inaba M, Asaga T, Momiyama N, Ichikawa Y, Yoshimoto M, Morita S, Shimada H.(19/22) Feasibility of AC/EC followed by weekly paclitaxel in node-positive breast cancer in Japan. Anticancer Res. 2009 May;29(5):1515-20.
Takahashi T, Togo S, Kumamoto T, Watanabe K, Kubota T, Ichikawa Y, Endo I, Kunisaki C, Nagashima Y, Fujimoto J, Shimada H. (6/11) Transfection of NF-kappaB decoy oligodeoxynucleotides into macrophages reduces murine fatal liver failure after excessive hepatectomy. J Surg Res. 2009 Jun 15;154(2):179-86.
Yoneda K, Iida H, Endo H, Hosono K, Akiyama T, Takahashi H, Inamori M, Abe Y, Yoneda M, Fujita K, Kato S, Nozaki Y, Ichikawa Y, Uozaki H, Fukayama M, Shimamura T, Kodama T, Aburatani H, Miyazawa C, Ishii K, Hosomi N, Sagara M, Takahashi M, Ike H, Saito H, Kusakabe A, Nakajima A. (9/26) Identification of Cystatin SN as a novel tumor marker for colorectal cancer. Int J Oncol. 2009 Jul;35(1):33-40.
Fujii S, Shimada H, Yamagishi S, Ota M, Kunisaki C, Ike H, Ichikawa Y. (7/7) Evaluation of intraperitoneal lavage cytology before colorectal cancer resection. Int J Colorectal Dis. 2009 Aug;24(8):907-14.
Ishikawa T, Sasaki T, Miyajima E, Shimizu D, Nozawa A, Kawachi K, Takase A, Miyazaki N, Tomioka R, Kikuchi M, Amari Y, Fukuno Y, Takeda H, Hayashi T, Onaka S, Ichikawa Y, Shimada H. (16/17) Pathological examination with two-millimetre serial sectioning for sentinel lymph node biopsies in breast cancer. Eur J Surg Oncol. 2009 Aug;35(8):895-6.
Ichikawa Y, Goto A, Hirokawa S, Kijima M, Ishikawa T, Chishima T, Suwa H, Yamamoto H, Yamagishi S, Osada S, Ota M, Fujii S. (1/12) Allergic reactions to oxaliplatin in a single institute in Japan. Jpn J Clin Oncol. 2009 Sep;39(9):616-20.
Shimada H, Tanaka K, Endou I, Ichikawa Y. (4/4) Treatment for colorectal liver metastases: a review. Langenbecks Arch Surg. 2009 Nov;394(6):973-83.
Goshima Y, Usui H, Shiozawa T, Hida T, Kuraoka S, Takeshita S, Yamashita N, Ichikawa Y, Kamiya Y, Gotoh T, Gotoh T. (8/11) Computational analysis of the effects of antineoplastic agents on axonal transport. J Pharmacol Sci. 2010;114(2):168-79.
Uchiyama T, Goto A, Sakai E, Sekino Y, Iida H, Endo H, Hosono K, Sakamoto Y, Koide T, Takahashi H, Yoneda M, Tokoro C, Abe Y, Shimamura T, Kobayashi N, Kubota
K, Maeda S, Nakajima A, Ichikawa Y, Inamori M. (18/19) Endoscopic hemostasis through gastrostomy. Endoscopy. 2010;42 Suppl 2:E270.
Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama
Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S. (3/12) High expression of atypical
protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence. Ann Surg Oncol. 2010 Jan;17(1):81-8.
Fujii S, Ota M, Yamagishi S, Kunisaki C, Osada S, Suwa H, Ichikawa Y, Shimada H. (7/8) A Y-shaped vinyl hood that creates pneumoperitoneum in laparoscopic rectal cancer surgery (Y-hood method.): a new technique for laparoscopic low anterior resection. Surg Endosc. 2010 Feb;24(2):476-84.
Ichikawa Y, Miyagi Y, Fujii S, Ota M, Yamagishi S, Hasegawa S, Saito S, Ike H, Ohki S, Nakano A, Matsumura N, Ishikawa T, Kunizaki C, Shimada H.(1/12) Gastrointestinal stromal tumor with two genetic abnormalities on different alleles: report of a case. Surg Today. 2010 Mar;40(3):262-6.
Fujii S, Ota M, Ichikawa Y, Yamagishi S, Osada S, Suwa H, Kunisaki C, Ohki S, Endo I. (3/9) Paraaortic lymph node metastasis showed CR to UFT/LV therapy in elderly rectal cancer. Hepatogastroenterology. 2010 May-Jun;57(99-100):472-6.
Ishikawa T, Shimizu D, Sasaki T, Morita S, Tanabe M, Ota I, Kawachi K, Nozawa A, Chishima T, Ichikawa Y, Endo I, Shimada H. (10/12) A human epidermal growth factor receptor 2 expression-based approach to neoadjuvant chemotherapy for operable breast cancer. Jpn J Clin Oncol. 2010 Jul;40(7):620-6.
Narui K, Ishikawa T, Kito A, Shimizu D, Chishima T, Momiyama N, Ichikawa Y, Sasaki T, Nozawa A, Inayama Y, Shimada H, Endo I. (6/11) Observational study of blue dye-assisted four-node sampling for axillary staging in early breast cancer. Eur J Surg Oncol. 2010 Aug;36(8):731-6.
Fujii S, Ota M, Ichikawa Y, Yamagishi S, Watanabe K, Tatsumi K, Watanabe J, Suwa H, Oshima T, Kunisaki C, Ohki S, Endo I, Shimada H. (3/13) Comparison of short, long-term surgical outcomes and mid-term health-related quality of life after laparoscopic and open resection for colorectal cancer: a case-matched control study. Int J Colorectal Dis. 2010 Nov;25(11):1311-23.
Ota M, Fujii S, Ichikawa Y, Suwa H, Tatsumi K, Watanabe K, Tanaka K, Akiyama
H, Endo I. (3/9) Clinical characteristics of rectal cancer involving the anal canal. J Gastrointest Surg. 2011 Mar;15(3):460-5.
Fujii S, Watanabe K, Ota M, Yamagishi S, Kunisaki C, Osada S, Ike H, Ichikawa Y, Endo I, Shimada H. (8/10) Solo surgery in laparoscopic colectomy: a case-matched study comparing robotic and human scopist. Hepatogastroenterology. 2011 Mar-Apr;58(106):406-10.
Nojiri K, Tanaka K, Nagano Y, Ueda M, Matsuo K, Ota M, Ichikawa Y, Shimada H, Endo I. (7/9) Efficacy of surgery for lung metastases from colorectal cancer synchronous to or following that for liver metastases. Anticancer Res. 2011 Mar;31(3):1049-54.
Makino H, Shimada H, Morioka D, Kunisaki C, Morita T, Matsuyama R, Kubota T, Shimizu D, Ichikawa Y, Tanaka K, Matsuo K, Togo S, Endo I, (9/13) Nagashima Y, Okazaki Y, Hayashizaki Y. Analysis of gene expression profiles in fatal hepatic failure after hepatectomy in mice. J Surg Res. 2011 Jul;169(1):36-43.
Tanaka K, Ichikawa Y, Endo I. (2/3) Liver resection for advanced or aggressive colorectal cancer metastases in the era of effective chemotherapy: a review. Int J Clin Oncol. 2011 Oct;16(5):452-63. doi: 10.1007/s10147-011-0291-6.
Ishikawa T, Shimizu D, Yamada A, Sasaki T, Morita S, Tanabe M, Kawachi K, Nozawa A, Chishima T, Kimura M, Ichikawa Y, Endo I. (11/12) Impacts and predictors of cytotoxic anticancer agents in different breast cancer subtypes. Oncol Res. 2012; 20(2-3):71-9.
Tanabe M, Endo I, Masunari H, Sugita M, Morioka D, Ishikawa T, Ichikawa Y, Shimada H. (7/8) Is lymph-node micrometastasis in gallbladder cancer a significant prognostic factor? Hepatogastroenterology. 2012 Jan-Feb;59(113):31-5.
Fujii S, Watanabe K, Ota M, Watanabe J, Ichikawa Y, Yamagishi S, Tatsumi K, Suwa H, Kunisaki C, Taguri M, Morita S, Endo I. (5/12) Laparoscopic colorectal cancer surgery by a colon lifting-up technique that decreases the number of access ports: comparison by propensity scoring of short-term and long-term outcomes with standard multiport laparoscopic surgery. Surg Laparosc Endosc Percutan Tech. 2012 Feb;22(1): 38-45.
Fujii S, Watanabe K, Ota M, Watanabe J, Ichikawa Y, Yamagishi S, Tatsumi K, Suwa H, Kunisaki C, Taguri M, Morita S, Endo I.(5/12) Single-incision laparoscopic
surgery using colon-lifting technique for colorectal cancer: a matched case-control comparison with standard multiport laparoscopic surgery in terms of short-term results and access instrument cost. Surg Endosc. 2012 May;26(5):1403-11.
Tanaka K, Kumamoto T, Nojiri K, Takeda K, Ichikawa Y, Endo I. (5/6) Timing of two-stage liver resection during chemotherapy for otherwise unresectable colorectal metastases. World J Surg. 2012 Aug;36(8):1832-41.
Yamada Y, Yamaguchi T, Matsumoto H, Ichikawa Y, Goto A, Kato K, Hamaguchi T, Shimada Y. (5/8) Phase II study of oral S-1 with irinotecan and bevacizumab (SIRB) as first-line therapy for patients with metastatic colorectal cancer. Invest New Drugs. 2012 Aug;30(4):1690-6. doi: 10.1007/s10637-011-9743-0.
Momiyama M, Kumamoto T, Suetsugu A, Kishimoto H, Chishima T, Tanaka K, Akiyama H, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. (8/11) Major liver resection stimulates stromal recruitment and metastasis compared with repeated minor resection. J Surg Res. 2012 Nov;178(1):280-7.
Shimizu D, Ishikawa T, Tanabe M, Sasaki T, Ichikawa Y, Chishima T, Endo I.(5/7) Preoperative endocrine therapy with goserelin acetate and tamoxifen in hormone receptor-positive premenopausal breast cancer patients. Breast Cancer. 2012 Nov 25. [Epub ahead of print] PubMed PMID: 23184499.
Ishikawa T, Shimizu D, Kito A, Ota I, Sasaki T, Tanabe M, Yamada A, Arioka H, Shimizu S, Wakasugi J, Mori R, Chishima T, Ichikawa Y, Endo I. (13/14) Breast cancer manifested by hematologic disorders. J Thorac Dis. 2012 Dec;4(6):650-4.
Okano Y, Nezu U, Enokida Y, Lee MT, Kinoshita H, Lezhava A, Hayashizaki Y, Morita S, Taguri M, Ichikawa Y, Kaneko T, Natsumeda Y, Yokose T, Nakayama H, Miyagi Y, Ishikawa T. (10/16) SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women. PLoS One. 2013 Sep 11;8(9):e73794.
Tanaka K, Hiroshima Y, Nakagawa K, Kumamoto T, Nojiri K, Takeda K, Ota M, Ichikawa Y, Endo I. (8/9) Two-stage hepatectomy with effective perioperative chemotherapy does not induce tumor growth or growth factor expression in liver metastases from colorectal cancer. Surgery. 2013 Feb;153(2):179-88.
Yoshihama Y, Izumisawa Y, Akimoto K, Satoh Y, Mizushima T, Satoh K, Chida K, Takagawa R, Akiyama H, Ichikawa Y, Kunisaki C, Inayama Y, Endo I, Nagashima Y, Ohno S. (10/15) High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis. Cancer Sci.2013 Feb;104(2):259-65.
Yamada A, Ishikawa T, Ota I, Kimura M, Shimizu D, Tanabe M, Chishima T, Sasaki T, Ichikawa Y, Morita S, Yoshiura K, Takabe K, Endo I. (9/13) High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival. Breast Cancer Res Treat. 2013 Feb;137(3):773-82.
Shimada K, Ishikawa T, Nakamura F, Shimizu D, Chishima T, Ichikawa Y, Sasaki T, Endo I, Nagashima Y, Goshima Y. (6/10) Collapsin response mediator protein 2 is involved in regulating breast cancer progression. Breast Cancer. 2013 Feb 5.[Epub ahead of print] PubMed PMID: 23381229.
Hino-Shishikura A, Suzuki A, Minamimoto R, Shizukuishi K, Oka T, Tateishi U, Sugae S, Ichikawa Y, Horiuchi C, Inoue T. (8/10) Biodistribution and radiation dosimetry of [¹⁸F]-5-fluorouracil. Appl Radiat Isot. 2013 May;75:11-7.
Fujii S, Ishibe A, Ota M, Yamagishi S, Watanabe K, Watanabe J, Kanazawa A,Ichikawa Y, Oba M, Morita S, Hashiguchi Y, Kunisaki C, Endo I. (8/13) Short-term results of a randomized study between laparoscopic and open surgery in elderly colorectal cancer patients. Surg Endosc. 2013 Oct 12. [Epub ahead of print] PubMed PMID:24122242.
116. Shimada K, Ishikawa T, Yoneyama S, Kita K, Narui K, Sugae S, Shimizu D, Tanabe M, Sasaki T, Chishima T, Ichikawa Y, Endo I. (11/12) Early-onset brain metastases in a breast cancer patient after pathological complete response to neoadjuvant chemotherapy. Anticancer Res. 2013 Nov;33(11):5119-21.
Kumamoto T, Tanaka K, Matsuo K, Takeda K, Nojiri K, Mori R, Taniguchi K,
Matsuyama R, Ueda M, Akiyama H, Ichikawa Y, Ota M, Endo I. (11/13) Adjuvant hepatic arterial infusion chemotherapy with 5-Fluorouracil and interferon after curative resection of hepatocellular carcinoma: a preliminary report. Anticancer Res. 2013 Dec;33(12):5585-90.
Hiroshima Y, Nakamura F, Miyamoto H, Mori R, Taniguchi K, Matsuyama R, AkiyamaH, Tanaka K, Ichikawa Y, Kato S, Kobayashi N, Kubota K, Nagashima Y, Goshima Y, Endo I. 9/15) Collapsin response mediator protein 4 expression is associated with liver metastasis and poor survival in pancreatic cancer. Ann Surg Oncol. 2013 Dec;20 Suppl 3:S369-78.
Watanabe J, Tatsumi K, Ota M, Suwa Y, Suzuki S, Watanabe A, Ishibe A, Watanabe K, Akiyama H, Ichikawa Y, Morita S, Endo I. (10/12) The impact of visceral obesity on surgical outcomes of laparoscopic surgery for colon cancer. Int J Colorectal Dis. 2013 Dec 3. [Epub ahead of print] PubMed PMID: 24297037.
Ichikawa Y, Goto A, Kobayashi N, Ota M, Tokuhisa M, Ishibe A, Watanabe J, Watanabe K, Ishikawa T, Tanaka K, Akiyama H, Fujii S and Endo I. (1/13) Does Resection of Primary Lesions Show Survival Benefit for Stage IV Colorectal Cancer Patients with Unresectable Metastases? Hepato-Gastroenterology 2013; 60:00-00 doi 10.5754/hge 13459
Kumamoto T, Tanaka K, Takeda K, Nojiri K, Mori R, Taniguchi K, Matsuyama R, Ueda M, Sugita M, Ichikawa Y, Nagashima Y, Endo I. (10/12) Intrahepatic cholangiocarcinoma arising 28 years after excision of a type IV-A congenital choledochal cyst: report of a case. Surg Today. 2014 Feb;44(2):354-8.
Homma Y, Taniguchi K, Murakami T, Nakagawa K, Nakazawa M, Matsuyama R, Mori R, Takeda K, Ueda M, Ichikawa Y, Tanaka K, Endo I. (10/12) Immunological impact of neoadjuvant chemoradiotherapy in patients with borderline resectable pancreatic ductal adenocarcinoma. Ann Surg Oncol. 2014 Feb;21(2):670-6.
Yamamoto S, Tanaka K, Takeda K, Akiyama H, Ichikawa Y, Nagashima Y, Endo I.(5/7) Patients with CD133-Negative Colorectal Liver Metastasis Have a Poor Prognosis After Hepatectomy. Ann Surg Oncol. 2014 Feb 20.
Homma Y, Taniguchi K, Nakazawa M, Matsuyama R, Mori R, Takeda K, Ichikawa Y, Tanaka K, Endo I. (7/9) Changes in the immune cell population and cell proliferation in peripheral blood after gemcitabine-based chemotherapy for pancreatic cancer. Clin Transl Oncol. 2014 Mar;16(3):330-5.

胃切開創の創傷治癒とepidermal growth factorについての実験的研究 市川 靖史 日本消化器外科学会誌 26(1) 8-17 1993年
癌患者cDNA BANKの作成-GenePlateを用いた固相上でのcDNA合成と保存- がん治療のあゆみ 15 33-41 1995年
大腸腺腫におけるマトリライシンmRNAの発現 消化器癌の発生と進展 7 227-229 1995年
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大腸癌肝転移の機序と対策-遺伝子治療を目ざして- 石川 孝, 市川 靖史, 籾山 信義, 池 秀之, 山口 茂樹, 舛井 秀宣, 南湖 正男, 山岡 博之, 三橋 将人, 秋田谷 龍男, 嶋田 紘 日本消化器外科学会雑誌 29(4) 878-883 1996年
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MMP阻害剤による癌転移治療 外科 60(12) 1643-1648 1998年
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抗癌剤感受性試験とcDNAマイクロアレイによる遺伝子発現解析 癌治療と宿主 13(3) 243-250 2001年
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LOH 外科 第64巻、第12号