竹内 康雄 たけうち やすお 先生

Umeda M, Kobayashi H, Takeuchi Y, Hayashi J, Morotome-Hayashi Y, Yano K, Aoki A, Ohkusa T, Ishikawa I. High prevalence of Helicobacter pylori detected by PCR in the oral cavities of periodontitis patients. J Periodontol. 2003.01; 74 (1): 129-134.

竹内 康雄, 青木 章, 平塚 浩一, Chanthoeun Chui , 一ノ瀬 顕子, 上窪 彩乃, 和泉 雄一. 【「抗菌的PDTについて」】歯科治療における抗菌的光線力学治療の応用 日本レーザー医学会誌. 2018.01; 38 (4): 457-469.

竹内康雄，青木 章，平塚浩一，Chanthoeun Chui，一ノ瀬顕子, 上窪彩乃，和泉雄一. 歯科治療における抗菌的光線力学治療の応用． 日本レーザー医学会誌. 2018.04; 38 (4): 457-470.

Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y, Nakase T. Detection of Treponema socranskii associated with human periodontitis by PCR. Microbiol Immunol. 1999; 43 (5): 485-490.

Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y. Rapid detection and quantification of five periodontopathic bacteria by real-time PCR. Microbiol Immunol. 2001; 45 (1): 39-44.

Takeuchi Y, Umeda M, Sakamoto M, Benno Y, Huang Y, Ishikawa I. Treponema socranskii, Treponema denticola, and Porphyromonas gingivalis are associated with severity of periodontal tissue destruction. J Periodontol. 2001.10; 72 (10): 1354-1363.

Sakamoto M, Takeuchi Y, Umeda M, Ishikawa I, Benno Y. Application of terminal RFLP analysis to characterize oral bacterial flora in saliva of healthy subjects and patients with periodontitis. J Med Microbiol. 2003.01; 52 (Pt 1): 79-89.

Huang Y, Umeda M, Takeuchi Y, Ishizuka M, Yano-Higuchi K, Ishikawa I. Distribution of Bacteroides forsythus genotypes in a Japanese periodontitis population. Oral Microbiol Immunol. 2003.08; 18 (4): 208-214.

Baehni PC, Takeuchi Y. Anti-plaque agents in the prevention of biofilm-associated oral diseases. Oral Dis. 2003.09; 9 Suppl 1 23-29.

Takeuchi Y, Umeda M, Ishizuka M, Huang Y, Ishikawa I. Prevalence of periodontopathic bacteria in aggressive periodontitis patients in a Japanese population. J Periodontol. 2003.10; 74 (10): 1460-1469.

Umeda M, Takeuchi Y, Noguchi K, Huang Y, Koshy G, Ishikawa I. Effects of nonsurgical periodontal therapy on the microbiota. Periodontol 2000. 2004; 36 98-120.

Umeda M, Miwa Z, Takeuchi Y, Ishizuka M, Huang Y, Noguchi K, Tanaka M, Takagi Y, Ishikawa I. The distribution of periodontopathic bacteria among Japanese children and their parents. J Periodontal Res. 2004.12; 39 (6): 398-404.

Wang D, Kawashima Y, Nagasawa T, Takeuchi Y, Kojima T, Umeda M, Oda S, Ishikawa I. Elevated serum IgG titer and avidity to Actinobacillus actinomycetemcomitans serotype c in Japanese periodontitis patients. Oral Microbiol Immunol. 2005.06; 20 (3): 172-179.

Takeuchi Y, Aramaki M, Nagasawa T, Umeda M, Oda S, Ishikawa I. Immunoglobulin G subclass antibody profiles in Porphyromonas gingivalis-associated aggressive and chronic periodontitis patients. Oral Microbiol Immunol. 2006.10; 21 (5): 314-318.

Thiha K, Takeuchi Y, Umeda M, Huang Y, Ohnishi M, Ishikawa I. Identification of periodontopathic bacteria in gingival tissue of Japanese periodontitis patients. Oral Microbiol Immunol. 2007.06; 22 (3): 201-207.

Chen YW, Iwai T, Umeda M, Nagasawa T, Huang Y, Takeuchi Y, Ishikawa I. Elevated IgG titers to periodontal pathogens related to Buerger disease. Int J Cardiol. 2007.10; 122 (1): 79-81.

Takeuchi Y, Guggenheim B, Filieri A, Baehni P. Effect of chlorhexidine/thymol and fluoride varnishes on dental biofilm formation in vitro. Eur J Oral Sci. 2007.12; 115 (6): 468-472.

栗原 伸久, 井上 芳徳, 岩井 武尚, 梅田 誠, 竹内 康雄, 石川 烈. 動脈疾患における新しい危険因子 歯周病菌と動脈病変 医学のあゆみ. 2003.04; 205 (2): 175-176.

Chen YW, Umeda M, Nagasawa T, Takeuchi Y, Huang Y, Inoue Y, Iwai T, Izumi Y, Ishikawa I. Periodontitis may increase the risk of peripheral arterial disease. Eur J Vasc Endovasc Surg. 2008.02; 35 (2): 153-158.

竹内 康雄, 芝 多佳彦. 【歯周外科の基本テクニック 術前検査からメインテナンスまで】Chapter2 歯周外科手術の基本テクニック 切開 メスの使い方から切開線のデザインまで 歯界展望. 2017.12; 別冊 (歯周外科の基本テクニック 術前検査からメインテナンスまで): 54-71.

Kitanaka Y, Takeuchi Y, Hiratsuka K, Aung N, Sakamaki Y, Nemoto T, Meinzer W, Izumi Y, Iwata T, Aoki A. The effect of antimicrobial photodynamic therapy using yellow-green LED and rose bengal on Porphyromonas gingivalis. Photodiagnosis and photodynamic therapy, Tokyo Medical and Dental University. 2020.12; 32 102033.

Sugawara Y, Imai K, Kashimada A, Moriyama K, Baba S, Nishikomori R, Motegi M, Takeuchi Y, Morio T. Autoinflammatory phenotypes in Aicardi-Goutières syndrome with interferon upregulation and serological autoimmune features. J Allergy Clin Immunol. 2018.03; 141 (3): 1135-1138.

Chigasaki O, Takeuchi Y, Aoki A, Sasaki Y, Mizutani K, Aoyama N, Ikeda Y, Gokyu M, Umeda M, Ishikawa I, Izumi Y. A cross-sectional study on the periodontal status and prevalence of red complex periodontal pathogens in a Japanese population. J Oral Sci. 2018.06; 60 (2): 293-303.

Yoshida Y, Churei H, Takeuchi Y, Wada T, Uo M, Izumi Y, Ueno T. Novel antibacterial mouthguard material manufactured using silver-nanoparticle-embedded ethylene-vinyl acetate copolymer masterbatch. Dental Materials Journal. 2018.06; 37 (3): 437-444.

Lee BS, Shih KS, Lai CH, Takeuchi Y, Chen YW. Surface property alterations and osteoblast attachment to contaminated titanium surfaces after different surface treatments: An in vitro study. Clinical implant dentistry and related research. 2018.08; 20 (4): 583-591.

Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Udagawa S, Takeuchi Y, Ohtsu A, Kohda T, Tohara H, Miyasaka N, Hirota T, Tamari M, Izumi Y. Endotoxemia by Porphyromonas gingivalis injection aggravates non-alcoholic fatty liver disease, disrupts glucose/lipid metabolism, and alters gut microbiota in mice. Frontiers in Microbiology. 2018.10; 9 2470.

Ohtsu A, Takeuchi Y, Katagiri S, Suda W, Maekawa S, Shiba T, Komazaki R, Udagawa S, Sasaki N, Hattori M, Izumi Y. Influence of Porphyromonas gingivalis in gut microbiota of streptozotocin-induced diabetic mice. Oral diseases. 2019.01; 25 (3): 868-880.

Ikeda E, Shiba T, Ikeda Y, Suda W, Nakasato A, Takeuchi Y, Azuma M, Hattori M, Izumi Y. Deep sequencing reveals specific bacterial signatures in the subgingival microbiota of healthy subjects. Clinical oral investigations. 2019.03; 23 (3): 1489-1493.

Funahashi K, Shiba T, Watanabe T, Muramoto K, Takeuchi Y, Ogawa T, Izumi Y, Sekizaki T, Nakagawa I, Moriyama K. Functional dysbiosis within dental plaque microbiota in cleft lip and palate patients. Progress in orthodontics. 2019.03; 20 (1): 11.

Aung N, Aoki A, Takeuchi Y, Hiratsuka K, Katagiri S, Kong S, Shujaa Addin A, Meinzer W, Sumi Y, Izumi Y. The effects of ultraviolet light-emitting diodes with different wavelengths on periodontopathic acteria In Vitro. Photobiomodulation, photomedicine, and laser surgery. 2019.05; 37 (5): 288-297.

Ikeda E, Shiba T, Ikeda Y, Suda W, Nakasato A, Takeuchi Y, Azuma M, Hattori M, Izumi Y. Japanese subgingival microbiota in health vs disease and their roles in predicted functions associated with periodontitis. Odontology. 2019.09; 108 (2): 280-291.

Ye C, Kobayashi H, Katagiri S, Miyasaka N, Takeuchi Y, Kuraji R, Izumi Y. The relationship between the anti-Porphyromonas gingivalis immunoglobulin G subclass antibody and small for gestational age delivery: a longitudinal study in pregnant Japanese women. International dental journal. 2020.03; 70 (4): 296-302.

Ogawa M, Katagiri S, Koyanagi T, Maekawa S, Shiba T, Ohsugi Y, Takeuchi Y, Ikawa T, Takeuchi S, Sekiuchi T, Arai Y, Kazama R, Wakabayashi N, Izumi Y, Iwata T. Accuracy of cone beam computed tomography in evaluation of palatal mucosa thickness. Journal of Clinical Periodontology. 2020.04; 47 (4): 479-488.

Udagawa S, Katagiri S, Maekawa S, Takeuchi Y, Komazaki R, Ohtsu A, Sasaki N, Shiba T, Watanabe K, Ishihara K, Sato N, Miyasaka N, Izumi Y. Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontologica Scandinavica. 2018.01; 1-9.

Komatsu K, Shiba T, Takeuchi Y, Watanabe T, Koyanagi T, Nemoto T, Shimogishi M, Shibasaki M, Katagiri S, Kasugai S, Iwata T. Discriminating microbial community structure between peri-Implantitis and periodontitis with integrated metagenomic, metatranscriptomic, and network analysis Frontiers in Cellular and Infection Microbiology. 2020.12; 10 596490.

Chigasaki O, Aoyama N, Sasaki Y, Takeuchi Y, Mizutani K, Ikeda Y, Gokyu M, Umeda M, Izumi Y, Iwata T, Aoki A. Porphyromonas gingivalis, the most influential pathogen in red-complex bacteria: A cross-sectional study on the relationship between bacterial count and clinical periodontal status in Japan J Periodontol. 2021.04; 92 (12): 1719-1729.

Rophukdeekul S, Tabata M, Ratanaporncharoen C, Takeuchi Y, Somboon P, Boonlue W, Miyahara Y, Sriyudthsak M. Quantitative assessment of periodontal bacteria using a cell-based immunoassay with functionalized QCM Chemosensors. 2021.06; 9 (7): 159.

Tanabe G, Churei H, Takeuchi Y, Hayashi K, Kanasaki A, Yoshida Y, Toma J, Araie Y, Ueno T. Antibacterial effect of a disinfectant spray for sports mouthguards on Streptococcus sobrinus Dental research journal. 2021.07; 18 59.

Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154.

Tanabe G, Hasunuma T, Inai Y, Takeuchi Y, Kobayashi H, Hayashi K, Shimizu S, Kamiya N, Churei H, Sumita Y, Suzuki K, Moriya N, Ueno T. Potential assessment of dehydration during high-intensity training using a capacitance sensor for oral mucosal moisture: evaluation of elite athletes in a field-based survey. Chemosensors. 2021.07; 9 (8): 196.

Shiba T, Komatsu K, Sudo T, Sawafuji R, Saso A, Ueda S, Watanabe T, Nemoto T, Kano C, Nagai T, Ohsugi Y, Katagiri S, Takeuchi Y, Kobayashi H, Iwata T. Comparison of periodontal bacteria of Edo and modern periods using novel diagnostic approach for periodontitis with micro-CT. Frontiers in cellular and infection microbiology. 2021.09; 11 723821.

Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T. Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021.10; e0088621.

Shiba T, Katagiri S, Komatsu K, Nemoto T, Takeuchi Y, Chen B, Zhou YS, Iwata T. Treatment of peri-implantitis caused by malpositioning and an extra implant: a case report International Journal of Periodontics & Restorative Dentistry. 2022.01; 42 (1): e15-e20.

Hayashi K, Takeuchi Y, Shimizu S, Tanabe G, Churei H, Kobayashi H, Ueno T. Continuous oral administration of sonicated P. gingivalis delays rat skeletal muscle healing post-treadmill training International Journal of Environmental Research and Public Health. 2022.10; 19 (20):

Tsuchida S, Satoh M, Kawashima Y, Sogawa K, Kado S, Sawai S, Nishimura M, Ogita M, Takeuchi Y, Kobyashi H, Aoki A, Kodera Y, Matsushita K, Izumi Y, Nomura F. Application of quantitative proteomic analysis using tandem mass tags for discovery and identification of novel biomarkers in periodontal disease. Proteomics. 2013.08; 13 (15): 2339-2350.

Wang D, Nagasawa T, Chen Y, Ushida Y, Kobayashi H, Takeuchi Y, Umeda M, Izumi Y. Molecular mimicry of Aggregatibacter actinomycetemcomitans with b2 glycoprotein I. Oral Microbiol Immunol. 2008.10; 23 (5): 401-405.

Chen YW, Nagasawa T, Wara-Aswapati N, Ushida Y, Wang D, Takeuchi Y, Kobayashi H, Umeda M, Inoue Y, Iwai T, Ishikawa I, Izumi Y. Association between periodontitis and anti-cardiolipin antibodies in Buerger disease. J Clin Periodontol. 2009.10; 36 (10): 830-835.

Aoyama N, Suzuki J, Wang D, Ogawa M, Kobayashi N, Hanatani T, Takeuchi Y, Izumi Y, Isobe M. Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix metalloproteinase-2 induction. J Periodont Res. 2011.04; 46 (2): 176-183.

Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y. Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in patients with chronic periodontitis. J Periodontol. 2012.06; 83 (6): 766-772.

Chui C, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Blue LED inhibits the growth of Porphyromonas gingivalis by suppressing the expression of genes associated with DNA replication and cell division. Lasers Surg Med. 2012.12; 44 (10): 856-864.

Koyanagi T, Sakamoto M, Takeuchi Y, Maruyama N, Ohkuma M, Izumi Y. Comprehensive microbiological findings in peri-implantitis and periodontitis. J Clin Periodontol. 2013.03; 40 (3): 218-226.

Bharti P, Katagiri S, Nitta H, Nagasawa T, Kobayashi H, Takeuchi Y, Izumiyama H, Uchimura I, Inoue S, Izumi Y. Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus. Obes Res Clin Pract. 2013.03; 7 (2): e129-e138.

Ye C, Katagiri S, Miyasaka N, Bharti P, Kobayashi H, Takeuchi Y, Momohara Y, Sekiguchi M, Takamine S, Nagasawa T, Izumi Y. The anti-phospholipid antibody-dependent and independent effects of periodontopathic bacteria on threatened preterm labor and preterm birth. Arch Gynecol Obstet. 2013.07; 288 (1): 65-72.

Taniguchi Y, Aoki A, Mizutani K, Takeuchi Y, Ichinose S, Takasaki AA, Schwarz F, Izumi Y. Optimal Er:YAG laser irradiation parameters for debridement of microstructured fixture surfaces of titanium dental implants. Lasers Med Sci. 2013.07; 28 (4): 1057-1068.

Aoki A, Mizutani K, Mikami R, Ohsugi Y, Kobayashi H, Akizuki T, Taniguchi Y, Takeuchi Y, Katagiri S, Sasaki Y, Komaki M, Meinzer W, Izumi Y, Iwata T. Er: YAG laser-assisted comprehensive periodontal pocket therapy (Er-LCPT) for residual periodontal pocket treatment: a randomized controlled clinical trial. Journal of periodontology. 2023.04;

Chui C, Aoki A, Takeuchi Y, Sasaki Y, Hiratsuka K, Abiko Y, Izumi Y. Antimicrobial effect of photodynamic therapy using high-power blue light-emitting diode and red-dye agent on Porphyromonas gingivalis. J Periodont Res. 2013.12; 48 (6): 696-705.

Maruyama N, Maruyama F, Takeuchi Y, Aikawa C, Izumi Y, Nakagawa I. Intraindividual variation in core microbiota in peri-implantitis and periodontitis. Scientific reports. 2014.10; 4 6602.

Ichinose-Tsuno A, Aoki A, Takeuchi Y, Kirikae T, Shimbo T, Lee MC, Yoshino F, Maruoka Y, Itoh T, Ishikawa I, Izumi Y. Antimicrobial photodynamic therapy suppresses dental plaque formation in healthy adults: a randomized controlled clinical trial. BMC Oral Health. 2014.12; 14 152.

Mayumi Ogita, Sachio Tsuchida, Akira Aoki, Mamoru Satoh, Sayaka Kado, Masanori Sawabe, Hiromi Nanbara, Hiroaki Kobayashi, Yasuo Takeuchi, Koji Mizutani, Yoshiyuki Sasaki, Fumio Nomura, Yuichi Izumi. Increased cell proliferation and differential protein expression induced by low-level Er:YAG laser irradiation in human gingival fibroblasts: proteomic analysis. Lasers Med Sci. 2015.09; 30 (7): 1855-1866.

Shiba T, Watanabe T, Kachi H, Koyanagi T, Maruyama N, Murase K, Takeuchi Y, Maruyama F, Izumi Y, Nakagawa I. Distinct interacting core taxa in co-occurrence networks enable discrimination of polymicrobial oral diseases with similar symptoms. Sci Rep. 2016.08; 6 30997.

Lee BS, Lee CC, Lin HP, Shih WA, Hsieh WL, Lai CH, Takeuchi Y, Chen YW. A functional chitosan membrane with grafted epigallocatechin-3-gallate and lovastatin enhances periodontal tissue regeneration in dogs. Carbohydr Polym. 2016.10; 151 790-802.

Uekubo A, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y. Effect of antimicrobial photodynamic therapy using rose bengal and blue light-emitting diode on Porphyromonas gingivalis in vitro: Influence of oxygen during treatment Laser Therapy. 2016.12; 25 (4): 299-308.

Ogata Y, Nakayama Y, Tatsumi J, Kubota T, Sato S, Nishida T, Takeuchi Y, Onitsuka T, Sakagami R, Nozaki T, Murakami S, Matsubara N, Tanaka M, Yoshino T, Ota J, Nakagawa T, Ishihara Y, Ito T, Saito A, Yamaki K, Matsuzaki E, Hidaka T, Sasaki D, Yaegashi T, Yasuda T, Shibutani T, Noguchi K, Araki H, Ikumi N, Aoyama Y, Kogai H, Nemoto K, Deguchi S, Takiguchi T, Yamamoto M, Inokuchi K, Ito T, Kado T, Furuichi Y, Kanazashi M, Gomi K, Takagi Y, Kubokawa K, Yoshinari N, Hasegawa Y, Hirose T, Sase T, Arita H, Kodama T, Shin K, Izumi Y, Yoshie H. Prevalence and risk factors for peri-implant diseases in Japanese adult patients. A cross-sectional multi-center study by periodontal specialist. J Oral Sci. 2017.03; 59 (1): 1-11.

S Maekawa, S Katagiri, Y Takeuchi, R Komazaki, A Ohtsu, S Udagawa, Y Izumi. Bone metabolic microarray analysis of ligature-induced periodontitis in streptozotocin-induced diabetic mice. J Periodont Res. 2017.04; 52 (2): 233-245.

Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi. Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Sci Rep. 2017.10; 7 (1): 13950.