藤田 知之 ふじた ともゆき 先生

来歴等

略歴

1994年 大阪大学医学部 卒業
1998年 米国 コロンビア大学 リサーチフェロー
2003年 ニュージーランド グリーンレーン病院 クリニカルフェロー
2007年 大阪大学大学院医学系研究科 心臓血管外科 助教
2009年 国立循環器病研究センター 心臓外科 医員
2014年 国立循環器病研究センター 心臓外科 部長
2020年 国立循環器病研究センター 心臓血管外科 部門長
2023年 東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 器官システム制御学講座 心臓血管外科学 教授

論文

• Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress. Nature Med. 2000;6(12):1355-61

  Yan SF, Fujita T, Lu J, Okada K, Shan Zou Y, Mackman N, Pinsky DJ, Stern DM

• Paradoxical Rescue from Ischemic Lung Injury by Inhaled Carbon Monoxide Driven by Derepression of Fibrinolysis. Nature Med. 2001;7(5):598-604

  Fujita T, Toda K, Karimova A, Yan SF, Naka Y, Yet SF, Pinsky DJ

• PKCbeta regulates ischemia/reperfusion injury in the lung. J Clin Invest. 2004;113(11):1615-23

  Fujita T, Asai T, Andrassy M, Stern DM, Pinsky DJ, Zou YS, Okada M, Naka Y, Schmidt AM, Yan SF.

• Carbon monoxide rescues ischemic lungs by interrupting MAPK-driven expression of early growth response 1 gene and its downstream target genes. Proc Natl Acad Sci U S A. 2006;103(13):5191-6 *SM and TF contributed equally.

  Mishra S*, Fujita T*, Lama VN, Nam D, Liao H, Okada M, Minamoto K, Yoshikawa Y, Harada H, Pinsky DJ.

• Long-term outcome of combined valve repair and maze procedure for nonrheumatic mitral regurgitation. J Thorac Cardiovasc Surg. 2010:140(6):1332-1337

  Fujita T, Kobayashi J, Toda K, Nakajima H, Iba Y, Shimahara Y, Yagihara T.

• Systemic hyperkalemia and mild hypothermia for valve surgery in patients with patent internal mammary artery graft. Interact Cardiovasc Thorac Surg. 2010 Jul; 11(1):3-5

  Fujita T, Kobayashi J, Nakajima H, Toda K.

• Clinical Impact of Combined Transplantation of Autologous Skeletal Myoblasts and Bone Marrow Mononuclear Cells in Patients with Severely Deteriorated Ischemic Cardiomyopathy. Surg Today. 2011; 41(8):1029-36

  T Fujita, T Sakaguchi, S Miyagawa, A Saito, N Sekiya, H Izutani, Y Sawa.

• Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case. Surg Today. 2012; 42(2):181-4

  Sawa Y, Miyagawa S, Sakaguchi T, Fujita T, Matsuyama A, Saito A, Shimizu T, Okano T.

• Risk factors for post-transplant low output syndrome. Eur J Cardiothorac Surg. 2012 Sep; 42(3):551-6

  Fujita T, Toda K, Yanase M, Seguchi O, Murata Y, Ishibashi-Ueda H, Kobayashi J, Nakatani T.

• Off-pump coronary artery bypass grafting for a left main lesion due to cardiac allograft vasculopathy in Japan: first report of a case. Surg Today. 2014 Oct; 44(10):1949-52

  Fujita T, Kobayashi J, Hata H, Murata Y, Seguchi O, Yanase M, Shimahara Y, Sato S, Nakatani T.

• Initial Experience of Internal mammary Artery Harvesting with Da Vinci Surgical System for Minimally Invasive Direct Coronary Artery Bypass. Surg Today. 2014 Dec; 44(12):2281-6

  Fujita T, Hata T, Shimahara Y, Sato S, Kobayashi J.

• Pathological analysis of the aortic valve after long-term left ventricular assist device support.　Eur J Cardiothorac Surg. 2014; 46(2):193-7

  Hata H, Fujita T, Ishibashi-Ueda H, Nakatani T, Kobayashi J.

• Right heart failure and benefits of adjuvant tricuspid valve repair in patients undergoing left ventricular assist device implantation. Eur J Cardiothorac Surg. 2014 Nov; 46(5):802-7

  Fujita T, Kobayashi J, Hata H, Seguchi O, Murata Y, Yanase M, Nakatani T.

• Hemodynamic Performance and Durability of Mosaic Bioprostheses for Aortic Valve Replacement, up to 13 Years.　Circ J. 2015; 79(5):1044-51

  Matsumoto Y, Fujita T, Hata H, Shimahara Y, Sato S, Kobayashi J.

• Long-term echocardiographic follow-up of untreated 2+ functional tricuspid regurgitation in patients undergoing mitral valve surgery†. Interact Cardiovasc Thorac Surg. 2016 ; 23(1):96-103

  Kusajima K, Fujita T, Hata H, Shimahara Y, Miura S, Kobayashi J.

• Reducing Prosthesis-Patient Mismatch With Edwards Magna Prosthesis for Aortic Valve Replacement. Circ J. 2017 ;81(4):468-475.

  Kume Y, Fujita T, Fukushima S, Hata H, Shimahara Y, Matsumoto Y, Yamashita K, Kobayashi J.

• Long-Term Outcomes of Suture vs. Ring Tricuspid Annuloplasty for Functional Tricuspid Regurgitation. Circ J. 2017 Sep 25;81(10):1432-1438.

  Hata H, Fujita T, Miura S, Shimahara Y, Kume Y, Matsumoto Y, Yamashita K, Kobayashi J.

• Should annuloplasty prosthesis be selected dependent on the location of prolapse in mitral valve repair for type II dysfunction? J Thorac Cardiovasc Surg. 2017 ;154(6):1915-1924.e6.

  Kawamoto N, Fujita T, Fukushima S, Hata H, Shimahara Y, Asakura K, Kobayashi J.

• Transcatheter Aortic Valve Implantation for Degenerated 19-mm Aortic Bioprosthetic Valve. Circ J. 2017 Dec 25;82(1):289-292

  Yamashita K, Fujita T, Fukushima S, Shimahara Y, Kume Y, Matsumoto Y, Kawamoto N, Hitsumoto T, Ito N, Hamatani Y, Okada A, Takahama H, Amaki M, Hasegawa T, Sugano Y, Kanzaki H, Anzai T, Yasuda S, Kobayashi J.

• Functional mitral stenosis after mitral valve repair for Type II dysfunction: determinants and impacts on long-term outcome. Eur J Cardiothorac Surg. 2018 Sep 1;54(3):453-459.

  Kawamoto N, Fujita T, Fukushima S, Shimahara Y, Kume Y, Matsumoto Y, Yamashita K, Asakura K, Kobayashi J.

• Intracranial mycotic aneurysm is associated with cerebral bleeding post-valve surgery for infective endocarditis. Interact Cardiovasc Thorac Surg. 2018 Nov 1;27(5):635-641.

  Kume Y, Fujita T, Fukushima S, Shimahara Y, Matsumoto Y, Yamashita K, Kawamoto N, Kobayashi J.

• Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis Complicated by Sigmoid Septum. Circ J. 2018 Nov 24;82(12):3090-3099.

  Yamashita K, Fujita T, Fukushima S, Shimahara Y, Kume Y, Matsumoto Y, Kawamoto N, Minami K, Kabata D, Kanzaki H, Izumi C, Anzai T, Kobayashi J.

• Benefit and Risk of Minimally Invasive Mitral Valve Repair for Type II Dysfunction　- Propensity Score-Matched Comparison. Circ J. 2018 Dec 25;83(1):224-231.

  Kawamoto N, Fukushima S, Shimahara Y, Yamasaki T, Matsumoto Y, Yamashita K, Kobayashi J, Fujita T.

• Prosthesis selection for repair of degenerative mitral valve disease. J Cardiol. 2019 Feb;73(2):184-185.

  Fujita T, Fukushima S, Kawamoto N, Kobayashi J.

• Contemporary outcomes of the concomitant CryoMaze procedure. Interact Cardiovasc Thorac Surg. 2019 Jul 1;29(1):28-34.

  Kakuta T, Fukushima S, Minami K, Shimahara Y, Yamasaki T, Matsumoto Y, Yamashita K, Kawamoto N, Tadokoro N, Kabata D, Kobayashi J, Fujita T.

• Multiple Coronary Artery Bypass Grafting for Kawasaki Disease-Associated Coronary Artery Disease. Ann Thorac Surg. 2019 Sep;108(3):799-805.

  Tadokoro N, Fujita T, Fukushima S, Shimahara Y, Matsumoto Y, Yamashita K, Kawamoto N, Tsuda E, Kitamura S, Kobayashi J.

• Early outcomes of transcatheter mitral valve replacement for degenerated bioprosthesis in Japanese (MITRAL VIV study): a four-case series.　Gen Thorac Cardiovasc Surg. 2019 May 25.

  Yamashita K, Fukushima S, Shimahara Y, Okada A, Amaki M, Kanzaki H, Izumi C, Yasuda S, Kobayashi J, Fujita T.

• Early postoperative heparinization reduce hemolysis in patients with HeartMate II devices. J Artif Organs. 2019 Sep 4.(Epub ahead of print)

  Matsumoto Y, Fukushima S, Shimahara Y, Kawamoto N, Tadokoro N, Kuroda K, Nakajima S, Watanabe T, Seguchi O, Yanase M, Fukushima N, Shimizu H, Kobayashi J, Fujita T.

• Benefits of the Modified Bicaval Anastomosis Technique for Orthotopic Heart Transplantation From a Size-Mismatched Marginal Donor. Circ J. 2019 Dec 25;84(1):61-68.

  Matsumoto Y, Fukushima S, Shimahara Y, Kawamoto N, Tadokoro N, Kitamura S, Kobayashi J, Fujita T.　Robotic minimally invasive direct coronary artery bypass for Kawasaki disease. Gen Thorac Cardiovasc Surg. 2019 Sep 25. 30) Kakuta T, Fukushima S, Shimahara Y, Yajima S, Kawamoto N, Tadokoro N, Fukushima N, Kitamura S, Kobayashi J, Fujita T.

• Benefits of the Modified Bicaval Anastomosis Technique for Orthotopic Heart Transplantation From a Size-Mismatched Marginal Donor. Circ J. 2019 Dec 25;84(1):61-68.

  Kakuta T, Fukushima S, Shimahara Y, Yajima S, Kawamoto N, Tadokoro N, Fukushima N, Kitamura S, Kobayashi J, Fujita T.

その他

• 【受賞】2012年　日本外科学会　研究奨励賞

• 【受賞】2012年　国立循環器病研究センター　ティーチング・アウォード

• 【受賞】2014年　国立循環器病研究センター　ティーチング・アウォード

• 【受賞】2018年　日本心臓血管外科学会　平成29年度臨床研究推進助成・多施設共同研究助成

• 【テレビ出演】2018年9月1日（土）　午後3時55分～午後5時30分 ABC朝日放送「完全密着！命を救え！"ナニワ"の名医たち」

• 【テレビ出演】2019年3月10日（日）BS朝日　命を救う！スゴ腕ドクター16～心臓病・不整脈・足のむくみ～