三條 伸夫 さんじょう のぶお 先生

来歴等

略歴

1990年 東京医科歯科大学医学部医学科 卒業
2004年 東京医科歯科大学大学院脳神経病態学 助手（現・助教）
2011年 東京医科歯科大学大学院脳神経病態学 講師
2016年 東京医科歯科大学大学院脳神経病態学分野 准教授
2016年 東京医科歯科大学大学院脳神経病態学分野 特任教授

論文

• 1. The presenilin proteins are components of multiple membrane-bound complexes which have different biological activities. Journal of Biological Chemistry 2004; 279(30): 31329-36. (*: equally contributed)

  Gu Y*, Sanjo N*, Chen F*, Hasegawa H, Petit A, Ruan X, Li, W., Shier, C., Kawarai, T., Schmitt-Ulms, G., Westaway, D., St George-Hyslop, P., Fraser, P. E.

• 2. Both the sequence and length of the C-terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. Journal of Biological Chemistry 2004; 279(45): 46455-63

  Hasegawa H, Sanjo N, Chen F, Gu YJ, Shier C, Petit A, Kawarai, T., Katayama, T., Schmidt, S. D., Mathews, P. M., Schmitt-Ulms, G., Fraser, P. E., St George-Hyslop, P.

• 3. Transient abundance of presenilin 1 fragments/nicastrin complex associated with synaptogenesis during development in rat cerebellum. Neurobiol Aging 2006; 27(1): 88-97.

  Uchihara T, Sanjo N, Nakamura A, Han K, Song SY, St George-Hyslop P, Fraser P.

• 4. St George-Hyslop P, Fraser P. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature 2006; 440(7088): 1208-12.

  Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D.

• 5. Fraser, Hidehiro Mizusawa. Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress. Journal of Alzheimer's Disease 2010; 20(1): 261-273

  Haifeng Jin, Nobuo Sanjo, Toshiki Uchihara, Kazuhiko Watabe, Peter St. George-Hyslop, Paul E.

• 6. Fraser. Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related γ-secretase. Neuroscience Lett 2010; 483(1): 53-56

  Nobuo Sanjo, Taiichi Katayama, Hiroshi Hasegawa, Haifeng Jin, Monika Duthie, Howard T.J. Mount, Hidehiro Mizusawa, Peter St George-Hyslop, Paul E.

• 7. Prospective 10-years surveillance for human prion diseases in Japan. Brain 133(10); 2010, 3043-57

  Ichiro Nozaki, Tsuyoshi Hamaguchi, Nobuo Sanjo, Kenji Sakai, Moeko Noguchi-Shinohara, Yosikazu Nakamura, Takeshi Sato, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Fumio Moriwaka, Yusei Shiga, Yoshiyuki Kuroiwa, Masatoyo Nishizawa, Shigeki Kuzuhara, Takashi Inuzuka, Masatoshi Takeda, Shigetoshi Kuroda, Koji Abe, Hiroyuki Murai, Shigeo Murayama, Jun Tateishi, Ichiro Takumi, Susumu Sirabe, Masafumi Harada, Masahito Yamada.

• 8. Multicentre, multiobserver study of diffusion-weighted and fluid-attenuated inversion recovery MRI for the diagnosis of sporadic Creutzfeldt?Jakob disease: a reliability and agreement study. BMJ open. , 2012, 2:e000649

  Koji Fujita, Masafumi Harada, Makoto Sasaki, Tatsuhiko Yuasa, Kenji Sakai, Tsuyoshi Hamaguchi, Nobuo Sanjo, Yusei Shiga, Katsuya Satoh, Ryuichiro Atarashi, Susumu Shirabe, Ken Nagata, Tetsuya Maeda, Shigeo Murayama, Yuishin Izumi, Ryuji Kaji, Masahito Yamada, Hidehiro Mizusawa.

• 9. Visual Reproduction on the Wechsler Memory Scale-Revised as a predictor of Alzheimer’s disease in Japanese patients with mild cognitive impairments. Dementia and Geriatric Cognitive Disorders 35. 165-176, 2013

  Takumi Hori, Nobuo Sanjo, Makoto Tomita, Hidehiro Mizusawa.

• 10. Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases. PLOS ONE, 2013

  Maya Higuma, Nobuo Sanjo, Katsuya Satoh, Yusei Shiga, Kenji Sakai, Ichiro Nozaki, Tsuyoshi Hamaguchi, Yosikazu Nakamura, Tetsuyuki Kitamoto, Susumu Shirabe, Shigeo Murayama, Masahito Yamada, Jun Tateishi, Hidehiro Mizusawa.

著書

• Creutzfeldt-Jakob病. 第12章，In: アルツハイマー病　認知症疾患　臨床医のための実践ガイド. 朝倉書店，2017, pp119-123　東京

• 慢性外傷性脳症. 第13章，In: アルツハイマー病　認知症疾患　臨床医のための実践ガイド. 朝倉書店，2017, pp124-130　東京

• プリオン病. 付録2. 感染症関連ガイドラインと使用上の注意. シリーズ《アクチュアル　脳・神経疾患の臨床》2014: 352-354

• プリオン病　第7章 プリオン病. シリーズ《アクチュアル　脳・神経疾患の臨床》2014: 278-285

• プリオン病. In: 永井良三　シリーズ総監修, E.感染症. 5章　神経内科疾患の診療. 神経内科研修ノート 2014: 372-375