東京科学大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 咬合機能矯正学 准教授
日本矯正歯科学会 会員 日本口蓋裂学会 会員 国際歯科研究学会(IADR) 会員
睡眠呼吸障害、骨軟骨代謝
続きを読む
日本矯正歯科学会 | 会員 |
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日本口蓋裂学会 | 会員 |
国際歯科研究学会(IADR) | 会員 |
東京科学大学病院
2001年
東京医科歯科大学 歯学部 歯学科(2001年3月 長尾優学術奨励賞 受賞)
卒業
2005年
東京医科歯科大学 医歯学総合研究科 咬合機能矯正学 博士課程
修了
2005年
東京医科歯科大学 歯学部附属病院 診療科 育成系診療科 矯正歯科外来
医員(歯病)
2006年
東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 咬合機能矯正学
助教
2010年
アメリカ合衆国・ミシガン大学アナーバー校 歯学部歯科矯正学小児歯科学講座 Prof. Dr. Sunil Kapila Lab
研究員
2010年
日本学術振興会
海外特別研究員
2013年
東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 咬合機能矯正学
講師
2015年
東京医科大学 大学院医学研究科法医学講座
客員研究員
2018年
東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 咬合機能矯正学
講師
2022年
東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 口腔機能再構築学講座 咬合機能矯正学
准教授
Sako E, Hosomichi J.. Alteration of bFGF expression with growth and age in rat molar periodontal ligament. Angle Orthod. 2010.09; 80 (5): 904-911.
Park Y, Hosomichi J, Ge C, Xu J, Franceschi R, Kapila S. Immortalization and characterization of mouse temporomandibular joint disc cell clones with capacity for multi-lineage differentiation. Osteoarthr Cartil. 2015.09; 23 (9): 1532-1542.
Kuma Y, Usumi-Fujita R, Hosomichi J, Oishi S, Maeda H, Nagai H, Shimizu Y, Kaneko S, Shitano C, Suzuki J, Yoshida K, Ono T.. Impairment of nasal airway under intermittent hypoxia during growth period in rats. Arch Oral Biol. 2014.11; 59 (11): 1139-1145.
Shimizu Y, Hosomichi J, Nakamura S, Ono T.. Micro-computed tomography analysis of changes in the periodontal ligament and alveolar bone proper induced by occlusal hypofunction of rat molars. Korean J Orthod. 2014.09; 44 (5): 263-267.
Shitano C, Baba O, Kaneko S, Hosomichi J, Shimizu Y, Shibutani N, Usumi-Fujita R, Takano Y, Ono T.. Alveolar bone loss induced by the orthodontic tooth movement under hypofunctional conditions in rats. Orthodontic Waves. 2013.11; 72 (4): 148-155.
Shimizu Y, Ishida T, Hosomichi J, Kaneko S, Hatano K, Ono T.. Soft diet causes greater alveolar osteopenia in the mandible than in the maxilla. Arch Oral Biol. 2013.08; 58 (8): 907-911.
Usumi-Fujita R, Hosomichi J, Ono N, Shibutani N, Kaneko S, Shimizu Y, Ono T.. Occlusal hypofunction causes periodontal atrophy and VEGF/VEGFR inhibition in tooth movement. Angle Orthod. 2013.01; 83 (1): 48-56.
Kapila S, Park Y, Ahmad N, Hosomichi J, Hayami T, Tacon C.. Mechanisms for relaxin's modulation of MMPs and matrix loss in fibrocartilages. Ital J Anat Embryol. 2013; 118 (1 Suppl): 62-65.
Yasuhiro Shimizu, Jun Hosomichi, Sawa Kaneko, Naoki Shibutani, Takashi Ono. Effect of sympathetic nervous activity on alveolar bone loss induced by occlusal hypofunction in rats. Arch. Oral Biol.. 2011.11; 56 (11): 1404-1411.
Oishi S, Shimizu Y, Hosomichi J, Kuma Y, Nagai H, Maeda H, Usumi-Fujita R, Kaneko S, Shitano C, Suzuki J, Yoshida K, Ono T. Intermittent hypoxia induces disturbances in craniofacial growth and defects in craniofacial morphology. Arch Oral Biol. 2016.01; 61 115-124.
Shibutani N, Hosomichi J, Ishida Y, Soma K.. Influence of occlusal stimuli on the microvasculature in rat dental pulp. Angle Orthod. 2010.03; 80 (2): 316-321.
Wada H, Hosomichi J, Shimomoto Y, Soma K.. Influence of occlusal hypofunction on the elastic property and bone formation of rat alveolar bone. Orthodontic Waves. 2008.09; 67 (1): 9-14.
Termsuknirandorn S, Hosomichi J, Soma K.. Occlusal stimuli influence on the expression of IGF-1 and the IGF-1 receptor in the rat periodontal ligament. Angle Orthod. 2008.07; 78 (4): 610-616.
Hu FW, Hosomichi J, Kanno Z, Soma K.. The influence of occlusal stimuli on basic fibroblast growth factor expression in the periodontal healing of replanted teeth. J Med Dent Sci. 2008.03; 55 (1): 129-135.
Kishimoto G, Hosomichi J, Muramoto T, Kanno Z, Soma K.. Influence of estrogen cycle on temporomandibular joint synovial membrane in rat with deviated mandible. J Med Dent Sci. 2007.03; 54 (1): 79-85.
Hosomichi J, Yasui N, Koide T, Soma K, Morita I.. Involvement of the collagen I-binding motif in the anti-angiogenic activity of pigment epithelium-derived factor. Biochem Biophys Res Commun. 2005.09; 335 (3): 756-761.
細道 純, 鈴木 拓海, 渋谷 直樹, 細野 香澄, 山口 博之, 隈 陽一郎, 金香 佐和, 笠原 由紀, 大石 修史, 臼見 莉沙, 清水 康広, 小野 卓史. 矯正的歯の移動時におけるKi67およびLGR5陽性歯根膜細胞の局在変化 日本矯正歯科学会大会プログラム・抄録集. 2017.10; 76回 184.
細道純, 中浜健一, 森田育男.. 血管新生抑制因子PEDFによる血管新生の制御. 口腔病学会雑誌. 2003.12; 70 (4): 249.
Sato M, Asano T, Hosomichi J, Ono T, Nakata T. Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells. Biochemical and biophysical research communications. 2018.10; 506 (3): 716-722.
Narubhorn Ongprakobkul, Yuji Ishida, Kasumi Hatano-Sato, Kai Li, Sirima Petdachai, Risa Usumi-Fujita, Jun Hosomichi, Korapin Mahatumarat, Takashi Ono. Effects of local vs systemic administration of CXCR4 inhibitor AMD3100 on orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop. 2022.03;
Li K, Ishida Y, Hatano-Sato K, Ongprakobkul N, Hosomichi J, Usumi-Fujita R, Kaneko S, Yamaguchi H, Ono T. Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats. J Periodontol. 2021.07;
Hong H, Hosomichi J, Maeda H, Ishida Y, Usumi-Fujita R, Yoshida KI, Ono T. Selective β2-Adrenoceptor Blockade Rescues Mandibular Growth Retardation in Adolescent Rats Exposed to Chronic Intermittent Hypoxia. Front Physiol. 2021.06; 12 676270.
Yo-Ichiro Kuma, Jun Hosomichi, Hideyuki Maeda, Shuji Oishi, Risa Usumi-Fujita, Yasuhiro Shimizu, Sawa Kaneko, Jun-Ichi Suzuki, Ken-Ichi Yoshida, Takashi Ono. Intermittent hypoxia induces turbinate mucosal hypertrophy via upregulating the gene expression related to inflammation and EMT in rats. Sleep Breath. 2021.06; 25 (2): 677-684.
Hong H, Hosomichi J, Maeda H, Lekvijittada K, Oishi S, Ishida Y, Usumi-Fujita R, Kaneko S, Suzuki JI, Yoshida KI, Ono T. Intermittent hypoxia retards mandibular growth and alters RANKL expression in adolescent and juvenile rats. European Journal of Orthodontics. 2020.03;
Tang H, Yonemitsu I, Ikeda Y, Watakabe K, Shibata S, Hosomichi J, Ono T. Effects of unilateral nasal obstruction on the characteristics of jaw-closing muscles in growing rats. The Angle Orthodontist. 2019.01; 89 (1): 102-110.
Uchikawa Y, Hosomichi J, Suzuki JI, Yamaguchi H, Ishida Y, Hatano K, Usumi-Fujita R, Shimizu Y, Kaneko S, Uesugi S, Ono T.. Differential growth of craniofacial and tibial bones to sympathetic hyperactivity-related hypertension in rats. Archives of Oral Biology. 2019.01; 99 73-81.
Hosomichi J, Shibutani N, Yamaguchi H, Hatano K, Kuma Y, Suzuki T, Kaneko S, Ono T. Localization of leucine-rich repeat-containing G-protein-coupled receptor 5- and Ki67-positive periodontal cells expressing runt-related transcription factor 2 during tooth movement. Orthodontic Waves. 2018.12; 77 (4): 197-208.
Wirongrong Wongkitikamjorn, Jun Hosomichi, Eiji Wada, Hideyuki Maeda, Sirichom Satrawaha, Haixin Hong, Yukiko K Hayashi, Ken-Ichi Yoshida, Takashi Ono. Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats. Cureus. 2022.05; 14 (5): e25088.
Hatano K, Ishida Y, Yamaguchi H, Hosomichi J, Suzuki J, Usumi-Fujita R, Shimizu Y, Shibutani N, Kaneko S, Ono T. The chemokine receptor type 4 antagonist, AMD3100, interrupts experimental tooth movement in rats. Archives of Oral Biology. 2018.02; 86 35-39.
Yamaguchi H, Ishida Y, Hosomichi J, Suzuki JI, Hatano K, Usumi-Fujita R, Shimizu Y, Kaneko S, Ono T. Ultrasound microbubble-mediated transfection of NF-κB decoy oligodeoxynucleotide into gingival tissues inhibits periodontitis in rats in vivo PLoS One. 2017.11; 1 (11): e0186264.
Hosomichi J, Maeda H, Kuma Y, Oishi S, Yoshida KI, Ono T. . Differential effects of intermittent hypoxia on phenotypic and metabolic features of airway muscles in weaning- and adolescent-aged rats. Sleep Medicine. 2017.11; 40 e135.
Yamaguchi H, Ishida Y, Hosomichi J, Suzuki J, Usumi-Fujita R, Shimizu Y, Kaneko S, Ono T. A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method. Int J Oral Sci. 2017.06; 9 (2): 80-86.
Kasahara Y, Usumi-Fujita R, Hosomichi J, Kaneko S, Ishida Y, Shibutani N, Shimizu Y, Okito O, Oishi S, Kuma Y, Yamaguchi H, Ono T. Low-intensity pulsed ultrasound reduces periodontal atrophy in occlusal hypofunctional teeth. Angle Orthod. 2017.05; 87 (5): 709-716.
Hosomichi J, Kuma Y, Oishi S, Nagai H, Maeda H, Usumi-Fujita R, Shimizu Y, Kaneko S, Shitano C, Suzuki J, Yoshida K, Ono T. Intermittent hypoxia causes mandibular growth retardation and macroglossia in growing rats. Am J Orthod Dentofacial Orthop. 2017.02; 151 (2): 363-371.
Oishi S, Shimizu Y, Hosomichi J, Kuma Y, Nagai H, Maeda H, Usumi-Fujita R, Kaneko S, Shibutani N , Suzuki J, Yoshida K, Ono T. Intermittent hypoxia Influences alveolar bone proper microstructure via hypoxia-inducible factor and VEGF expression in periodontal ligaments of growing rats. Front phsyiol. 2016.09; 7 Article 416.
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