七野 浩之 しちの ひろゆき 先生

来歴等

略歴

1989年 山形大学医学部 卒業
1999年 日本大学 助手
2007年 日本大学 助教（医学部小児科）
2013年 公立阿伎留医療センター 小児科 部長
2014年 国立国際医療研究センター病院 小児科
2015年 国立国際医療研究センター病院 小児科 診療科長
2023年 国立国際医療研究センター病院 小児科 医員

論文

• 1. Comprehensive treatment of advanced neuroblastoma involving autologous bone marrow transplant. Acta Pediatrica Japonica. 1995;37:493-499.

  Mugishima H, Harada K, Suzuki T, Chin M, Shimada T, Takamura M, Shichino H, Nagata T.

• 2. Treatment of aplastic anemia with antithymocyteglobulin,　cyclosporinA, methylprednisolone, danazole and recombinant human granulocyte-colony stimulating factor. Acta Pediatrica Japonica. 1996;38:644-647.

  Shichino H, Mugishima H, Takamura M, Shimada T, Suzuki T, Chin M, Harada K, Ryo S, Kojima S.

• 3. Hepatitis B virus infects human bone marrow cells and their progenitors. Nihon University Journal of Medicine. 1996;38;77-87.

  Mugishima H, Shichino H, Harada K.

• 4. Biomarker and morphological characteristics of Epstein-Barr virus- related hemophagocytic lymphohistiocytosis：Medical and Pediatric Oncology.1998;31:131-137.

  Imashuku S, Hibi S, Tabata Y, Sako M, Sekine Y, Hirayama K, Sakazaki H, Maeda　N, Kito H, Shichino H, Mugishima H.

• 5. Karyotypic Analyses of Hepatoblastoma report of two cases and review of the literature suggesting chromosomal loci responsible for the pathogenesis of this disease. Cancer Genetics and Cytogenetics. 1999;114:42-50.

  Nagata T, Mugishima H, Shichino H, Suzuki T, Chin M, Koshinaga S, Inoue M, Harada K.

• 6. Profiling of genes differentially expressed between fetal liver and postnatal liver using high-density oligonucleotide DNA array.　International Journal of Molecular Medicine. 2003;11:713_721.

  Nagata T, Takahashi Y, Ishii Y, Asai S, Sugahara M, Nishida Y, Murata A, Chin M, Shichino H, Koshinaga T, Fukuzawa M, Mugishima H.

• 7. Diagnostic Significance and Clinical Applications of Chimeric Genes in Ewing’s Sarcoma. Biological Pharmaceutical Bulletin.2003;26:585-588.

  Yoshino N, Kojima T, Asami S, Motohashi S, Yoshida Y, Chin M, Shichino H, Yoshida Y, Nemoto N, Kaneko M, Mugishima H, Suzuki T.

• 8. Significance of extensive Mongolian spots in Hunter’s syndrome. British Journal of Dermatology. 2003;148:1173-1178.

  Ochiai T, Ito K, Okada T, Chin M, Shichino H, Mugishima H.

• 9. Usefulness of tyroshine hydroxylase mRNA for diagnosis and detection of minimal residual disease in neuroblastoma. Biological Pharmaceutical Bulletin. 2004;27:315-318.

  Ito R, Asami S, Kagawa S, Motohashi S, Shichino H, Chin M, Yoshida Y, Nemoto N, Mugishima H, Suzuki T.

• 10. The effect of haematopoietic stem cell transplantation on papules with ‘pebbly’ appearance in Hunter’s syndrome. British Journal of Dermatology. 2003;151:207-211.

  Ito K, Ochiai T, Suzuki H, Chin M, Shichino H, Mugishima H.

• 11. Significance of surviving mRNA expression in prognosis of neuroblastoma. Biological Pharmaceutical Bulletin. 2005;28:565-568.　

  Ito R, Asami S, Motohashi S, Ootsuka S, Yamaguchi Y, Chin M, Shichino H, Yoshida Y, Nemoto N, Mugishima H, Suzuki T.

• 12. Ultrastructural findings of cutaneous nerves in patients with Hunter’s syndrome following hematopoietic stem cell transplant. Medical Molecular Morphology. 2005;38:118-122.

  Ochiai T, Ito K, Shichino H, Chin M, Mugishima H.

• 13. Analyses of novel prognostic factors in neuroblastoma patients. Biological Pharmaceutical Bulletin. 2007;30:2294-2299.

  Ootsuka S, Asami S, Sasaki T, Yoshida Y, Nemoto N, Shichino H, Chin M, Mugishima H, Suzuki T.

• 14. Natural history of extensive Mongolian spots in mucopolysaccharidosis type II (Hunter syndrome):　a survey among 52 Japanese patients. Journal of European Academy of Dermatology and Venereology. 2007;21:1082-1085.

  Ochiai T, Suzuki Y, Kato T, Shichino H, Chin M, Mugishima M, Orii T.

• 15. Treatment of Ewing’s sarcoma using an antisense oligodeoxynucleotide to regulate the cell cycle. Biological Pharmaceutical Bulletin. 2008;34:391-394.

  Asami S, Chin M, Sasaki T, Shichino H, Yoshida Y, Nemoto N, Mugishima H, Suzuki T.

• 16. Treatment responses for disseminated intravascular coagulation in 25 children treated with recombinant thrombomodulin: A single institution experience. Thromb Res. 2012;130:e289-293.

  Yagasaki H,Kato M,Shimozawa K,Hirai M,Nishikawa E,Okuma H,Ishii W,Imai Y, Matsumura M, Yonezawa R,Yoshikawa K,Shichino H,Chin M,Mugishima H.

• 17. Immunosuppressive therapy with horse anti-thymocyte globulin and cyclosporine as treatment for fulminant aplastic anemia in children.Ann Hematol. 2014;93(5):747-52.

  Yagasaki H, Shichino H, Ohara A, Kobayashi R, Yabe H, Ohga S, Hamamoto K, Ohtsuka Y, Shimada H, Inoue M, Muramatsu H, Takahashi Y, Kojima S.

• 18. Secondary cancers after a childhood cancer diagnosis: a nationwide hospital-based retrospective cohort study in Japan. Int J Clin Oncol.2015;21(3): 506_516.

  Ishida Y,Qiu D,Miho Maeda,Fujimoto J,Kigasawa H,Kobayashi R,Sato M,Okamura J,Yoshinaga S,Rikiishi T,Hiroyuki Shichino,Kiyotani C,Kudo K,Asami K,Hiroki Hori,Kawaguchi H,Inada H,Adachi S,Atsushi Manabe,Kuroda T.

• 19. Serum Tenascin-C as a Novel Predictor for Risk of Coronary Artery Lesion and Resistance to Intravenous Immunoglobulin in Kawasaki Disease- A Multicenter Retrospective Study.Circ J. 2016;80(11): 2376-2381.

  Okuma Y, Suda K, Nakaoka H, Katsube Y, Mitani Y, Yoshikane Y, Ichida F, Matsushita T,H iroyuki Shichino, Shiraishi I, Abe J, Hiroe M, Yoshida T, Imanaka-Yoshida K.

• 20. Impact of persistent left ventricular regional wall motion abnormalities in childhood cancer survivors after anthracycline therapy: Assessment of global left ventricular myocardial performance by 3D speckle-tracking echocardiography. J Cardiol. 2017 Oct;70(4):396-401.

  Okuma H, Noto N, Tanikawa S, Kanezawa K, Hirai M, Shimozawa K, Yagasaki H, Shichino H, Takahashi S.

• 21. Phase I study of perifosine monotherapy in patients with recurrent or refractory neuroblastoma. Pediatr Blood Cancer 2017;64:e26623

  Kimikazu Matsumoto, Hiroyuki Shichino,Hiroshi Kawamoto, Yoshiyuki Kosaka, Motoaki Chin, Koji Kato, Hideo Mugishima.

• 22. Secondary cancer after a childhood cancer diagnosis: viewpoints considering primary cancer. Int J Clin Oncol. 2018;23:1178-1188.

  Yasushi Ishida, Miho Maeda,Souichi Adachi,Hiroko Inada,Hiroshi Kawaguchi,Hiroki Hori, Atsushi Ogawa, Kazuko Kudo,Chikako Kiyotani,Hiroyuki Shichino, Takeshi Rikiishi, Ryoji Kobayashi, Maho Sato,Jun Okamura,Hiroaki Goto,Atsushi Manabe,Shinji Yoshinaga,Dongmei Qiu, Junichiro Fujimoto, Tatsuo Kuroda.

• 23. Results of a phase II trial for high-risk neuroblastoma treatment protocol JN-H-07: a report from the Japan Childhood Cancer Group Neuroblastoma Committee (JNBSG). Int J Clin Oncol. 2018;23(5):965-973.

  Hishiki T, Matsumoto K, Ohira M4, Kamijo T, Shichino H, Kuroda T, Yoneda A, Soejima T, Nakazawa A, Takimoto T, Yokota I, Teramukai S, Takahashi H, Fukushima T, Kaneko T, Hara J, Kaneko M, Ikeda H, Tajiri T, Nakagawara A.Japan Childhood Cancer Group Neuroblastoma Committee (JNBSG).

• 24. SARS-CoV-2 infection among returnees on charter flights to Japan from Hubei, China: a report from National Center for Global Health and Medicine.Global Health & Medicine. 2020;2(2):107-111.

  Hayakawa K , Kutsuna S, Kawamata T, Sugiki Y, Nonaka C, Tanaka K, Shoji M, Nagai M, Tezuka S, Shinya K, Saito H, Harada T, Moriya N, Tsuboi M, Norizuki M, Sugiura Y, Osanai Y, Sugiyama M, Okuhama J, Kanda K, Wakimoto Y, Ujiie M, Morioka S, Yamamoto K, Kinoshita N, Ishikane M, Saito S, Moriyama Y, Ota M, Nakamura K, Nakamoto T, Ide S, Nomoto H, Akiyama Y, Suzuki T, Miyazato Y, Gu Y, Matsunaga N, Tsuzuki S, Fujitomo Y, Kusama Y, Shichino H, Kaneshige M, Yamanaka J, Saito M, Hojo M, Hashimoto M, Izumi S, Takasaki J, Suzuki M, Sakamoto K, Hiroi Y, Emoto S, Tokuhara M, Kobayashi T, Tomiyama K, Nakamura F, Ohmagari N, Sugiyama H.

• 25. A breathing movement sensor for chest radiography during inspiration in children aged less than 3 years: a prospective randomized controlled study.Bio Science Trends. 2020;14(3):200-205.

  Honda M, Haruyama R, Sugiura Y, Ohara K, Mochigi K, Kono Y, Shichino H, Uryu H, Mizoue T, Marutani T, Ebihara T, Uchiyama F, Makise S, Akashi H.

• 26. Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1eRelated Microglial Activation in Neonatal Hypoxic-Ischemic Encephalopathy.Morphologic Consideration.Am J Pathol.2021;191(7):1303-1313.

  Akamatsu T, Sugiyama T, Oshima T, Aoki Y, Mizukami A, Goishi K, Shichino H, Kato N, Takahashi N, Goto YI, Oka A, Itoh M.

• 27. Retrospective Analysis of INRG Clinical and Genomic Factors for 605 Neuroblastomas in Japan: A Report from the Japan Children’s Cancer Group Neuroblastoma Committee (JCCG-JNBSG).Biomolecules 2022, 12, 18. https://doi.org/10.3390/biom12010018

  Ohira M, Nakamura Y, Takimoto T, Nakazawa A, Hishiki T, Matsumoto K, Shichino H, Iehara T, Nagase H, Fukushima T,Yoneda A,Tajiri T, Nakagawara A,Kamijo T.

• 28. Adapting pediatric health care responses to the COVID-19 pandemic in Japan: A clinical perspective.Glob Health Med. 2022 Aug 31;4(4):242-246. doi: 10.35772/ghm.2022.01043.PMID: 36119789 Free PMC article.

  Yamanaka J, Takasago S, Horigome A, Hayashi M, Matsunashi S, Shioda S, Tanaka M, Seki J, Kaneshige M, Akamatsu T, Uryu H, Mochizuki S, Goishi K, Shichino H.

• 29. Outcome of children with relapsed high-risk neuroblastoma in Japan and analysis of the role of allogeneic hematopoietic stem cell transplantation. Jpn J Clin Oncol. 2022 May 5;52(5):486-492. doi: 10.1093/jjco/hyac007.PMID: 35137156

  Hara J, Nitani C, Shichino H, Kuroda T, Hishiki T, Soejima T, Mori T, Matsumoto K, Sasahara Y, Iehara T, Miyamura T, Kosaka Y, Takimoto T, Nakagawara A, Tajiri T; Japan Children’s Cancer Group (JCCG) Neuroblastoma Committee (JNBSG).

著書

• 1. 七野浩之,麦島秀雄:特発性血小板減少性紫斑病. 小児救急医療，小児内科小児外科編集委員会共編東京医学社　東京 1999,645-648

• 2. 七野浩之：神経芽腫.小児疾患の診断治療基準,小児内科小児外科編集委員会共編 第3版 東京医学社 東京2006,568-570

• 3. 七野浩之: 第3章A5インフォームドコンセント・インフォームドアセント.小児科研修ノート,永井良三 改訂第2版 診断と治療社 東京2014,207-209

• 4. 七野浩之：第I部総論 第２章 小児がん D小児がんにおける治療法〔抗がん化学療法〕2抗がん薬各論e．プラチナ製剤．小児血液・腫瘍学,特定非営利活動法人 日本小児血液・がん学会 診断と治療社 東京 2015,134-136

• 5. 佐藤典子,七野浩之：第II部 各論（疾患）第１章 血液・造血器疾患 C免疫異常 ２続発性免疫不全症 小児血液・腫瘍学,特定非営利活動法人 日本小児血液・がん学会　診断と治療社　東京2015,429-433

• 6. 家原知子,七野浩之,檜山英三,松本公一,米田光宏：第6章 神経芽腫．小児がん診療ガイドライン,一般社団法人日本小児血液・がん学会　2016年版　金原出版 東京2016,199-250

その他

• 1. 2022年 共同通信社配信 各地方紙 知ってほしい小児がん 全20回シリーズ