正木 康史 まさき やすふみ 先生

来歴等

論文

• Epidemiological analysis of multicentric and unicentric Castleman disease and TAFRO syndrome in Japan. J Clin Exp Hematop. 2019 Nov 8. doi: 10.3960/jslrt.19021.

  Masak Y, Kawabata H, Fujimoto S, Kawano M, Iwaki N, Kotani T, Nakashima A, Kurose N, Takai K, Suzuki R, Aoki S.

• 2019 updated diagnostic criteria and disease severity classification for TAFRO syndrome. Int J Hematol. 111(1), 155-158.. doi: 10.1007/s12185-019-02780-1.

  Masaki Y, Kawabata H, Takai K, Tsukamoto N, Fujimoto S, Ishigaki Y, Kurose N, Miura K, Nakamura S, Aoki S & Japanese TAFRO syndrome research team.

• The potential role of follicular helper T cells in idiopathic multicentric Castleman disease with and without TAFRO syndrome.Pathol Res Pract. 2019 Oct;215(10):152563. doi: 10.1016/j.prp.2019.152563. Epub 2019 Jul 26.

  Kurose N, Guo X, Shioya A, Mizutani KI, Kumagai M, Fujimoto S, Kawabata H, Masaki Y, Takai K, Aoki S, Nakamura S, Yamada S.

• An extranodal histopathological analysis of idiopathic multicentric Castleman disease with and without TAFRO syndrome. Pathol Res Pract. 2018 Dec 26. pii: S0344-0338(18)31509-7. doi: 10.1016/j.prp.2018.12.025.

  Kurose N, Mizutani KI, Kumagai M, Shioya A, Guo X, Nakada S, Fujimoto S, Kawabata H, Masaki Y, Takai K, Aoki S, Kojima M, Nakamura S, Kida M, Yamada S.

• Intravascular large B-cell lymphoma involving large blood vessels. Pathol Int. 2019 Feb;69(2):97-103. doi: 10.1111/pin.12751. Epub 2019 Jan 23.

  Sato S, Teshima S, Nakamura N, Ohtake T, Kikuchi J, Kishi H, Nomura K, Kurose N, Masaki Y, Tamaru J.

• A case of osteosarcoma manifesting systemic inflammation and histological features mimicking plasma cell type Castleman disease. Intern Medicine, 2017 Dec;96(50):e9220. doi: 10.1097/MD.0000000000009220.

  Fujimoto S, Sakai T, Kawabata H, Kurose N, Yamada S, Doai M, Matoba M, Kawanami HI, Kawanami T, Mizuta S, Fukushima T, Mizumaki Y, Yamaguchi M, Masaki Y.

• Improved prognosis of extranodal NK/T cell lymphoma, nasal type of nasal origin but not extranasal origin. Ann Hematol. 2019 Apr 19. doi: 10.1007/s00277-019-03689-9.

  Yamaguchi M, Suzuki R, Miyazaki K, Amaki J, Takizawa J, Sekiguchi N, Kinoshita S, Tomita N, Wada H, Kobayashi Y, Niitsu N, Ando T, Maeda T, Saito B, Matsuoka H, Sakai R, Kubota N, Masaki Y, Kameoka Y, Asano N, Oguchi M, Katayama N.

• Impaired expression of innate immunityrelated genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD. Mod Rheumatol. 2019 Jul 11:1-7. doi: 10.1080/14397595.2019.1621475.

  Nakamura T, Satoh-Nakamura T, Nakajima A, Kawanami T, Sakai T, Fujita Y, Iwao H, Miki M, Masaki Y, Okazaki T, Ishigaki Y, Kawano M, Yamada K, Matsui S, Saeki T, Kamisawa T, Yamamoto M, Hamano H, Origuchi T, Hirata S, Tanaka Y, Tsuboi H, Sumida T, Okazaki K, Tanaka M, Chiba T, Mimori T, Umehara H.

• Is TAFRO syndrome a subtype of idiopathic multicentric Castleman disease? Am J Hematol. 2019;94:975–983.doi: 10.1002/ajh.25554.

  Fujimoto S, Sakai T, Kawabata H, Kurose N, Yamada S, Takai K, Aoki S, Kuroda J, Ide M, Setoguchi K, Tsukamoto N, Iwao-Kawanami H, Kawanami T, Mizuta S, Fukushima T, Masaki Y.

• on behalf of the Japanese IgG4-Related Disease Working Consortium. IgG4-related disease in the Japanese population:a genome-wide association study. Lancet Rheumatol 2019 August 6, 2019.http://dx.doi.org/10.1016/S2665-9913(19)30006-2

  Terao C, Ota M, Iwasaki T, Shiokawa M, Kawaguchi S, Kuriyama K, Kawaguchi T, Kodama Y, Yamaguchi I, Uchida K, Higasa K, Yamamoto M, Kubota K, Yazumi S, Hirano K, Masaki Y, Maguchi H, Origuchi T, Matsui S, Nakazawa T, Shiomi H, Kamisawa T, Hasebe O, Iwasaki E, Inui K, Tanaka Y, Ohshima K, Akamizu T, Nakamura S, Nakamura S, Saeki T, Umehara H, Shimosegawa T, Mizuno N, Kawano M, Azumi A, Takahashi H, Mimori T, Kamatani Y, Okazaki K, Chiba T, Kawa S, Matsuda F,

• Bortezomib plus dexamethasone versus thalidomide plus dexamethasone for relapsed or refractory multiple myeloma. Cancer Science 2018 DOI:10.1111/cas.13550

  Iida S, Wakabayashi M, Tsukasaki K, Miyamoto K, Maruyama D, Yamamoto K, Takatsuka Y, Kusumoto S, Kuroda J, Ando K, Kikukawa Y, Masaki Y, Kobayashi M, Hanamura I, Asai H, Nagai H, Shimada K, Tsukamoto N, Inoue Y, Tobinai K.

• Tentative diagnostic criteria and disease severity classification for Castleman disease: A report of the research group on Castleman disease in Japan. Mod Rheumatol.28（1）161-167,2018. doi: 10.1080/14397595.2017.1366093.

  Fujimoto S, Koga T, Kawakami A, Kawabata H, Okamoto S, Mizuki M, Yano S, Ide M, Uno K, Yagi K, Kojima T, Mizutani M, Tokumine Y, Nishimoto N, Fujiwara H, Nakatsuka SI, Shiozawa K, Iwaki N, Masaki Y, Yoshizaki K.

• Sjögren’s syndrome manifesting as clinicopathological features of TAFRO syndrome. A case report. Medicine (Baltimore). 2017 Dec;96(50):e9220. doi: 10.1097/MD.0000000000009220.

  Fujimoto S, Kawabata H, Kurose N, Kawanami-Iwao H, Sakai T, Kawanami T, Fujita Y, Fukushima T, Masaki Y.

• Remission of Refractory Ascites and Discontinuation of Hemodialysis after Additional Rituximab to Long-term Glucocorticoid Therapy in a Patient with TAFRO Syndrome. Intern Med 15;57(10):1433-1438,2018

  Tsurumi H, Fujigaki Y, Yamamoto T, Iino R, Taniguchi K, Nagura M, Arai S, Tamura Y, Ota T, Shibata S, Kondo F, Kurose N, Masaki Y, Uchida S.

• The clinicopathological comparison among nodal cases of idiopathic multicentric Castleman disease with and without TAFRO syndrome. Hum Pathol. 2018 Jul;77:130-138. doi: 10.1016/j.humpath.2018.04.001. Epub 2018 Apr 21.

  Kurose N, Futatsuya C, Mizutani KI, Kumagai M, Shioya A, Guo X, Aikawa A, Nakada S, Fujimoto S, Kawabata H, Masaki Y, Takai K, Aoki S, Kojima M, Nakamura S, Yamada S.

• Activities od the Ishikawa Prefectural joint committee of blood transfusion therapy – Appropriate use of albumin products, educational activities and role of pharmacists- . 社会薬学（Jpn J Soc Pharm） 37(1):2-8,2018

  Sugita N, Tanaka H, Satou H, Hutaki T, Miyamoto M, Yoneda S, Okamoto A, Taniguchi Y, Yamasita I, Nitta M, Komori M, Shiobara S, Kikuchi S, Takami A, Yamazaki H, Masaki Y.

• Dose-adjusted EPOCH chemotherapy for untreated peripheral T-cell lymphomas: a multicenter phase II trial of West-JHOG PTCL0707.Haematologica. 2017Dec;102(12):2097-2103. doi: 10.3324/haematol.2017.167742. Epub 2017 Sep 29.

  Maeda Y, Nishimori H, Yoshida I, Hiramatsu Y, Uno M, Masaki Y, Sunami K, Masunari T, Nawa Y, Yamane H, Gomyo H, Takahashi T, Yano T, Matsuo K, Ohshima K, Nakamura S, Yoshino T, Tanimoto M.

• A Host-Dependent Prognostic Model for Elderly Patients with Diffuse Large B-Cell Lymphoma. Oncologist. 2017 May;22(5):554-560 pii: theoncologist.2016-0260. doi: 10.1634/theoncologist.2016-0260.

  Miura K, Konishi J, Miyake T, Makita M, Hojo A, Masaki Y, Uno M, Ozaki J, Yoshida C, Niiya D, Kitazume K, Maeda Y, Takizawa J, Sakai R, Yano T, Yamamoto K, Sunami K, Hiramatsu Y, Kazutoshi Aoyama, Tsujimura H, Murakami J, Hatta Y, Kanno M.

• The Standard International Prognostic Index for Predicting the Risk of CNS Involvement in DLBCL without Specific Prophylaxis. Leuk Lymphoma. 2018 Jan;59(1):97-104. doi: 10.1080/10428194.2017.1330541.

  Tomita N, Yokoyama M, Yamamoto W, Watanabe R, Shimazu Y, Masaki Y, Tsunoda S, Hashimoto C, Murayama K, Yano T, Okamoto R, Kikuchi A, Tamura K, Sato K, Sunami K, Shibayama H, Takimoto R, Ohshima R, Takahashi H, Moriuchi Y, Kinoshita T, Yamamoto M, Numata A, Nakajima H, Miura I, Takeuchi K.

• Human recombinant Fab fragment from combinatorial libraries of a B cell lymphoma patient recognizes core protein of chondroitin sulfate proteoglycan 4. J Biochem 163(1)61-68,2017. doi.org/10.1093/jb/mvx065

  Egami Y, Narushima Y, Ohshima M, Yoshida A, Yoneta N, Masaki Y, Itoh K.

• A multicenter phase II prospective clinical trial of glucocorticoid for patients with untreated IgG4-related disease.Mod Rheumatol. 2017 Sep;27(5):849-854. doi: 10.1080/14397595.2016.1259602. Epub 2016 Dec 15.

  Masaki Y, Matsui S, Saeki T, Tsuboi H, Hirata S, Izumi Y, Miyashita T, Fujikawa K, Dobashi H, Susaki K, Morimoto H, Takagi K, Kawano M, Origuchi T, Wada Y, Takahashi N, Horikoshi M, Ogishima H, Suzuki Y, Kawanami T, Kawanami Iwao H, Sakai T, Fujita Y, Fukushima T, Saito M, Suzuki R, Morikawa Y, Yoshino T, Nakamura S, Kojima M, Kurose N, Sato Y, Tanaka Y, Sugai S, Sumida T.

• Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 version. Int J Hematol. 2016 Jun;103(6):686-92. doi: 10.1007/s12185-016-1979-1. Epub 2016 Mar 18.

  Masaki Y, Kawabata H, Takai K, Kojima M, Tsukamoto N, Ishigaki Y, Kurose N, Ide M, Murakami J, Nara K, Yamamoto H, Ozawa Y, Takahashi H, Miura K, Miyauchi T, Yoshida S, Momoi A, Awano N, Ikushima S, Ohta Y, Furuta NI, Fujimoto S, Kawanami HI, Sakai T, Kawanami T, Fujita Y, Fukushima　T, Nakamura　S,Kinoshita T , Aoki S.

• Isolation of vascular smooth muscle antigen-reactive CD4(+)αβTh1 clones that induce pulmonary vasculitis in MRL/Mp-Fas(+/+) mice. Cell Immunol. 2016 May;303:50-4. doi: 10.1016/j.cellimm.2016.03.004. Epub 2016 Mar 21.

  Fujita Y, Fujii T, Shimizu H, Sato T, Nakamura T, Iwao H, Nakajima A, Miki M, Sakai T, Kawanami T, Tanaka M, Masaki Y, Fukushima T, Okazaki T, Umehara H, Mimori T.

• CD14+ follicular dendritic cells in lymphoid follicles may play a role in the pathogenesis of IgG4-related disease. Biomedical Res (Tokyo) 36(2) 143-153,2015

  Satoh-Nakamura T, Kurose N, Kawanami T, Nakamura T, Iwao-Kawanami H, NakajimaA, Miki M, Sakai T, Fujita Y, Tanaka M, Fukushima T, Masaki Y.

• Shimosegawa T, Takahashi H, Takahira M, Tanaka A, Topazian M, Umehara H, Webster GJ, Witzig T, Yamamoto M, Zhang W, Chiba T, and Stone JH. International consensus guidance statement on the treatment of IgG4-related disease. Arthritis Rheum 2015 Jul;67(7):1688-99. doi: 10.1002/art.39132.

  Khosroshahi A, Wallace ZS, Crowe JL, Akamizu T, Azumi A, Carruthers MN, Chari S, Della-Torre E, Frulloni L, Goto H, Hart P, Kamisawa T, Kawa S, Kawano M, Kim MH, Kodama Y, Kubota K, Lerch MM, Lohr M, Masaki Y, Matsui S, Mimori T, Nakamura S, Nakazawa T, Ohara H, Okazaki K, Ryu JH, Saeki T, Schleinitz N, Shimatsu A,

• Decreased expression of innate immunity-related genes in peripheral blood mononuclear cells from patients with IgG4-related disease. PLoS One. 2015 May 14;10(5):e0126582. doi: 10.1371/journal.pone.0126582. eCollection 2015.

  Nakajima A, Masaki Y, Nakamura T, Kawanami T, Ishigaki Y, Takegami T, Kawano M, Yamada K, Tsukamoto N, Matsui S, Saeki T, Okazaki K, Kamisawa T, Miyashita T, Yakushijin Y, Fujikawa K, Yamamoto M, Hamano H, Origuchi T, Hirata S, Tsuboi H, Sumida T, Morimoto H, Sato T, Iwao H, Miki M, Sakai T, Fujita Y, Tanaka M, Fukushima T, Okazaki T, Umehara H.

• Prospective clinical study of R-CMD therapy for indolent B-cell lymphoma and mantle cell lymphoma from the Hokuriku Hematology Oncology Study Group. Medical Oncol (2015) 32:232. DOI 10.1007/s12032-015-0677-9

  Sakai T , Masaki Y, Otsuki N, Sakamaki I, Kishi S, Miyazono T, Urasaki Y, Murakami J, Satoh T, Nakamura T, Iwao H, Nakajima A, Kawanami T, Miki M, Fujita Y, Tanaka M, Fukushima T, Okazaki T, Ueda T.

• A case of probable IgG4-related disease involving the unilateral trigeminal nerve of the cheek region. Oral Radiol (2015) 31:193–198

  Yoshida H, Yasuda N, Hayashi T, Tsuji K, Wato M, Gamoh S, Shimizutani K, Akio Tanaka A, Masaki Y, Morita S.

• IgG4-related disease - Diagnostic methods and therapeutic strategies in Japan- J Clin Exp Hematop 2014,54(2):95-101

  Masaki Y, Shimizu H, Nakamura TS, Nakamura T, Nakajima A, Kawanami HI, Miki M, Sakai T, Kawanami T, Fujita Y, Tanaka M, Fukushima T.

• Clinical course after corticosteroid therapy in IgG4-related aortitis/periaortitis and periarteritis: a retrospective multicenter study. Arthritis Res Ther 2014 Jul 23;16(4):R156. doi: 10.1186/ar4671.

  Mizushima I, Inoue D, Yamamoto M, Yamada K, Saeki T, Ubara Y, Matsui S, Masaki Y, Wada T, Kasashima S, Harada K, Takahashi H, Notohara K, Nakanuma Y, Umehara H, Yamagishi M, Kawano M.

著書

• 【共著】臨床医必読最新IgG4関連疾患　改訂第2版．診断と治療社（東京）．編集主幹；岡崎和一、川　茂幸．　 正木康史．II-13. IgG4関連リンパ節症 治療と予後．pp170-172

• 【共著】正木康史、藤本信乃、黒瀬　望、川端　浩．特発性多中心性キャッスルマン病．新薬と臨床J.NewRem.&Clin 68(4)77-81(505-509.2019

• 【共著】正木康史、黒瀬　望、川端　浩． Castleman病，TAFRO症候群・血液専門医の視点より．腎と透析Vol.86増刊号　全身性疾患と腎update. pp307-309. （株）東京医学社　2019年

• 【著】正木康史．IgG4関連疾患の治療．日医雑誌147(2):255-259,2018

• 【著】正木康史. IgG4関連疾患：内科の立場から「教育セミナー3 IgG4関連疾患　耳鼻咽喉科と内科の立場から」口咽科　31（1）77-81,2018

• 【共著】「改訂第3版ステロイドの選び方・使い方ハンドブック」　山本一彦編集. 羊土社（東京都）　2018年3月25日　第2部　各疾患別ステロイドの使い方　 正木康史　2．血液疾患　pp113-139

• 【共著】シェーグレン症候群の診断と治療マニュアル　改訂第3版.(日本シェーグレン症候群学会編集、竹内　勤、川上　純、住田孝之監修) 診断と治療社（東京） 第4章 臨床症状 2 腺外症状 1）血液リンパ増殖性病変 p117-122 第4章 臨床症状 5 IgG4関連疾患 1）診断 p178-186

• 【共著】正木康史. 血管内リンパ腫. 血液疾患最新の治療2017−2019, pp177-179.　小澤敬也、中尾眞二、松村　到編（南江堂）2017年2月25日発行

• 【共著】正木康史.内科学 第11版（矢崎義雄総編集）（朝倉書店）2017年3月20日発行. 16-10 白血球系疾患1）総論（1）白血球減少症pp1967-1970, （2）白血球増加症 pp1970-1972.

• 【共著】北澤淳一、玉井佳子、藤田 浩、牧野茂義、正木康史、大本英次郎、小田秀隆、中村 弘、二木敏彦、黒田　優、立花直樹、松下　正．在宅赤血球輸血ガイド．日本輸血細胞治療学会誌63(5):664-673,2017

特許

• IgG4関連疾患診断用マーカー及びその利用（特許第5704684号「出願番号　特願2010-194326」）・平成27年3月6日「出願年月日　平成22年8月31日」／平成31年3月5日　特定承継による本権の移転

  正木康史、石垣靖人